sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4jwp | ACO | GCN5-related N-acetyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 1.000 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.549 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.520 | |
| 4jxr | ACO | Acetyltransferase | / | 0.509 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.488 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.482 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.481 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.478 | |
| 2ge3 | ACO | Probable acetyltransferase | / | 0.472 | |
| 4kvm | SER_ALA_SER_GLU_1XE | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.471 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.466 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.464 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.464 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.463 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.461 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.459 | |
| 4kub | COA | Uncharacterized protein | / | 0.459 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.458 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.456 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.455 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.455 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.452 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.451 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.450 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.444 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.443 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.441 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.441 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.440 |