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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4jwfSAHtRNA (guanine(9)-N1)-methyltransferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4jwfSAHtRNA (guanine(9)-N1)-methyltransferase/1.000
4jwhSAHtRNA (guanine(9)-N1)-methyltransferase/0.531
1xe55FEPlasmepsin-23.4.23.390.525
2feuCAMCamphor 5-monooxygenase1.14.15.10.524
2dftADPShikimate kinase2.7.1.710.514
3u9eCOALmo1369 protein/0.508
4jwjSAHtRNA (guanine(9)-N1)-methyltransferase/0.508
1v9aSAHUncharacterized protein/0.504
1f20FADNitric oxide synthase, brain1.14.13.390.496
1nooCAHCamphor 5-monooxygenase1.14.15.10.496
3w2jQRODihydroorotate dehydrogenase (fumarate)1.3.98.10.495
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.495
1rfuADPPyridoxal kinase2.7.1.350.494
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.493
3bc3OPTCathepsin L13.4.22.150.493
1uyuCAMCamphor 5-monooxygenase1.14.15.10.492
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.491
3gwfFADCyclohexanone monooxygenase/0.488
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.488
4z4pSAHHistone-lysine N-methyltransferase 2D2.1.1.430.488
4xboSAHtRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ2.1.1.2000.487
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.486
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.486
3a20FMNFMN-binding protein/0.485
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.484
4e2dFMNDehydrogenase/0.484
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.483
3h8bNSYCathepsin L13.4.22.150.482
4xr9NADCalS8/0.482
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.481
2g247IGRenin3.4.23.150.481
4m83ERYOleandomycin glycosyltransferase2.4.10.481
4yaoFMNNADPH--cytochrome P450 reductase/0.481
1xe65FPPlasmepsin-23.4.23.390.480
3bbhSFGRibosomal RNA small subunit methyltransferase Nep12.1.10.480
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.478
1t2cNAIL-lactate dehydrogenase1.1.1.270.478
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.478
3fwjCAMCamphor 5-monooxygenase1.14.15.10.478
3wrjCAMCamphor 5-monooxygenase1.14.15.10.478
4o1mNADEnoyl-acyl carrier reductase/0.478
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.478
1dz8CAMCamphor 5-monooxygenase1.14.15.10.477
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.477
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.477
1kh3ANPArgininosuccinate synthase/0.476
1yrdCAMCamphor 5-monooxygenase1.14.15.10.476
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.476
3toxNAPPutative oxidoreductase/0.476
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.475
1p0fNAPNADP-dependent alcohol dehydrogenase1.1.1.20.475
3p62FMNPentaerythritol tetranitrate reductase/0.475
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.475
3fwfCAMCamphor 5-monooxygenase1.14.15.10.474
3fwgCAMCamphor 5-monooxygenase1.14.15.10.474
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.474
2a7r5GPGMP reductase 2/0.473
3adaNADSubunit alpha of sarocosine oxidase/0.473
3lqfNADGalactitol dehydrogenase/0.473
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.473
1bwsNDPGDP-L-fucose synthase/0.472
3fwiCAMCamphor 5-monooxygenase1.14.15.10.472
3kb1ADPIron-sulfur cluster carrier protein/0.472
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.472
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.472
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.472
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.472
2q7vFADThioredoxin reductase/0.471
3ibqATPPyridoxal kinase/0.471
3omuIBDHeat shock protein 83/0.471
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.471
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.471
4uymVOR14-alpha sterol demethylase Cyp51B/0.471
1dz6CAMCamphor 5-monooxygenase1.14.15.10.470
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.470
3b70NAPEnoyl reductase LovC10.470
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.470
3tr05GPGuanylate kinase/0.470
3wrhCAMCamphor 5-monooxygenase1.14.15.10.470
3wrlCAMCamphor 5-monooxygenase1.14.15.10.470
4djaFAD(6-4) photolyase/0.470
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.470
1o76CAMCamphor 5-monooxygenase1.14.15.10.469
2g1n1IGRenin3.4.23.150.469
2uxoTACHTH-type transcriptional regulator TtgR/0.469
3gwfNAPCyclohexanone monooxygenase/0.469
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.469
3oijSAHRibosomal RNA small subunit methyltransferase NEP1/0.469
3w3oROEDihydroorotate dehydrogenase (fumarate)1.3.98.10.469
4dbzNDPPutative ketoacyl reductase1.3.10.469
4euaCOASuccinyl-CoA:acetate CoA-transferase/0.469
1h51FMNPentaerythritol tetranitrate reductase/0.468
2qboCAMCamphor 5-monooxygenase1.14.15.10.468
3l63CAMCamphor 5-monooxygenase1.14.15.10.468
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.468
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.468
1hdrNADDihydropteridine reductase1.5.1.340.467
1j9zFADNADPH--cytochrome P450 reductase/0.467
1t86CAMCamphor 5-monooxygenase1.14.15.10.467
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.467
3c1y2BADNA integrity scanning protein DisA/0.467
3gfbNADL-threonine 3-dehydrogenase/0.467
4ambDUDPutative glycosyl transferase/0.467
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.466
1pjcNADAlanine dehydrogenase/0.466
3w1xXRODihydroorotate dehydrogenase (fumarate)1.3.98.10.466
4tuvCPZCytochrome P450 1191.140.466
5d3qGDPDynamin-13.6.5.50.466
1l4lNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.465
1rfvADPPyridoxal kinase2.7.1.350.465
1w0kADPATP synthase subunit alpha, mitochondrial/0.465
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.465
2a1oCAMCamphor 5-monooxygenase1.14.15.10.465
2qbmCAMCamphor 5-monooxygenase1.14.15.10.465
3nl6TPSUncharacterized protein/0.465
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.465
4mcc21XtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.465
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.464
1t87CAMCamphor 5-monooxygenase1.14.15.10.464
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.464
3f03FMNPentaerythritol tetranitrate reductase/0.464
3s1dZIRCytokinin dehydrogenase 11.5.99.120.464
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.464
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
2qblCAMCamphor 5-monooxygenase1.14.15.10.463
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.463
3p82FMNPentaerythritol tetranitrate reductase/0.463
4kbyC2EStimulator of interferon genes protein/0.463
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
4yxm2BADNA integrity scanning protein DisA/0.463
1dz4CAMCamphor 5-monooxygenase1.14.15.10.462
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
2el0SAHDiphthine synthase/0.462
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.462
2vkeTACTetracycline repressor protein class D/0.462
3ctyFADProbable thioredoxin reductase/0.462
3w2uROUDihydroorotate dehydrogenase (fumarate)1.3.98.10.462
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.462
4o63NADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.462
4oqyNDP(S)-imine reductase/0.462
4yqfGDPSeptin-9/0.462
1bil0IURenin3.4.23.150.461
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
1h63FMNPentaerythritol tetranitrate reductase/0.461
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.461
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1vyrFMNPentaerythritol tetranitrate reductase/0.461
2a94AP0L-lactate dehydrogenase1.1.1.270.461
2aa3AP0L-lactate dehydrogenase/0.461
2nv4SAMS-adenosyl-L-methionine-binding protein AF_0241/0.461
2zaxCAMCamphor 5-monooxygenase1.14.15.10.461
3f8dFADNADH oxidase/thioredoxin reductase/0.461
3o7bSAHRibosomal RNA small subunit methyltransferase Nep1/0.461
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.461
4q71FADBifunctional protein PutA/0.461
4q72FADBifunctional protein PutA/0.461
1g1aNADdTDP-glucose 4,6-dehydratase/0.460
1l4hNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.460
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.460
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.460
2g20L1ARenin3.4.23.150.460
2q9cGNPSignal recognition particle receptor FtsY/0.460
3mdmFJZCholesterol 24-hydroxylase/0.460
3uylTYDProbable NDP-rhamnosyltransferase/0.460
3w233RODihydroorotate dehydrogenase (fumarate)1.3.98.10.460
4ejmNAPPutative zinc-binding dehydrogenase/0.460
4eu4COASuccinyl-CoA:acetate CoA-transferase/0.460
4l4eCAMCamphor 5-monooxygenase1.14.15.10.460
4lopSB4Mitogen-activated protein kinase 14/0.460
1tj0FADBifunctional protein PutA1.5.5.20.459
1xvaSAMGlycine N-methyltransferase2.1.1.200.459
2p20PRXAcetyl-coenzyme A synthetase/0.459
3f8rNAPNADH oxidase/thioredoxin reductase/0.459
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.459
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.459
3x2eNAIAdenosylhomocysteinase/0.459
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.459
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.459
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.458
2iyfERYOleandomycin glycosyltransferase2.4.10.458
2o4cNADErythronate-4-phosphate dehydrogenase/0.458
3c35KAIGlutamate receptor ionotropic, kainate 1/0.458
3gqvNAPEnoyl reductase LovC10.458
3hllI45Mitogen-activated protein kinase 14/0.458
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.458
3p74FMNPentaerythritol tetranitrate reductase/0.458
3qt62P0Mevalonate diphosphate decarboxylase/0.458
3tjzGNPADP-ribosylation factor 1/0.458
3w1tWRODihydroorotate dehydrogenase (fumarate)1.3.98.10.458
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.458
4ipw1G7Mycocyclosin synthase1.14.21.90.458
4jxrACOAcetyltransferase/0.458
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.458
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.457
1nzdUPGDNA beta-glucosyltransferase/0.457
1w6hTITPlasmepsin-23.4.23.390.457
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.457
2fy4COACholine O-acetyltransferase2.3.1.60.457
2gjlFMNNitronate monooxygenase1.13.12.160.457
2zbaZBATrichothecene 3-O-acetyltransferase/0.457
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.457
3r9uFADThioredoxin reductase/0.457
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.457
3w1rMRODihydroorotate dehydrogenase (fumarate)1.3.98.10.457
4g3rCAMCamphor 5-monooxygenase1.14.15.10.457
4jicFMNGTN Reductase/0.457
5a1tNAIL-lactate dehydrogenase/0.457
5a9sNAPPutative dehydrogenase/0.457
5c41ACPRibokinase/0.457
5cyoGDPSeptin-9/0.457
1t88CAMCamphor 5-monooxygenase1.14.15.10.456
1u71MXADihydrofolate reductase1.5.1.30.456
2a92NAIL-lactate dehydrogenase/0.456
2ft9CHDFatty acid-binding protein 2, liver/0.456
3lxiCAMCytochrome P450/0.456
3s7dLEU_SER_LYS_LYS_MLZN-lysine methyltransferase SMYD2/0.456
3ut5LOCTubulin beta chain/0.456
3w2lVRODihydroorotate dehydrogenase (fumarate)1.3.98.10.456
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.456
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.456
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.456
4hmsFMNPhenazine biosynthesis protein PhzG1.40.456
4k6fNAPPutative Acetoacetyl-CoA reductase/0.456
4kkyCAMCamphor 5-monooxygenase1.14.15.10.456
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.455
1x1aSAMC-20 methyltransferase/0.455
2xfsJ01Uncharacterized protein/0.455
2xvq9DSSerum albumin/0.455
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.455
3pgqGY3Acetyl-CoA carboxylase/0.455
4a802ANMajor pollen allergen Bet v 1-A/0.455
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.455
1bim0QBRenin3.4.23.150.454
1gqtACPRibokinase/0.454
1p9pSAHtRNA (guanine-N(1)-)-methyltransferase/0.454
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2iviACWIsopenicillin N synthase1.21.3.10.454
2yyeAPCSelenide, water dikinase2.7.9.30.454
3a6rFMNFMN-binding protein/0.454
3bbdSAHRibosomal RNA small subunit methyltransferase Nep12.1.10.454
3cyxROCGag-Pol polyprotein3.4.23.160.454
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
3f8pNADNADH oxidase/thioredoxin reductase/0.454
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.454
3gvhNADMalate dehydrogenase/0.454
3lsiFADPyranose 2-oxidase/0.454
3uf6CODLmo1369 protein/0.454
3vqsJT1Genome polyprotein/0.454
4m6jNDPDihydrofolate reductase1.5.1.30.454
1h50FMNPentaerythritol tetranitrate reductase/0.453
2g1s4IGRenin3.4.23.150.453
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.453
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.453
2whqHI6Acetylcholinesterase3.1.1.70.453
2xfyACXBeta-amylase3.2.1.20.453
3ai3NDPNADPH-sorbose reductase/0.453
3bgxMEFThymidylate synthase/0.453
3ggxGGXGag-Pol polyprotein/0.453
3rh7FMNUncharacterized protein/0.453
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.453
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.453
4ji91M3Tyrosine-protein kinase JAK2/0.453
4ke11R6Beta-secretase 13.4.23.460.453
4l4dCAMCamphor 5-monooxygenase1.14.15.10.453
4q73FADBifunctional protein PutA/0.453
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.453
4wjiNAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase/0.453
6cp4CAMCamphor 5-monooxygenase1.14.15.10.453
1kp2ATPArgininosuccinate synthase6.3.4.50.452
1o9bNAIQuinate/shikimate dehydrogenase/0.452
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.452
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.452
2jlaTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.452
2vprTDCTetracycline repressor protein class H/0.452
2y3rTIRTamL/0.452
3d8vUD1Bifunctional protein GlmU/0.452
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.452
3oiiSAHRibosomal RNA small subunit methyltransferase NEP1/0.452
4cd2FOLDihydrofolate reductase1.5.1.30.452
4ly91YYGlucokinase regulatory protein/0.452
4xfjANPArgininosuccinate synthase/0.452
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.451
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.451
1kl2FONSerine hydroxymethyltransferase/0.451
1yw2PGJMitogen-activated protein kinase 14/0.451
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2gnaGDUUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.451
2ii6C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.451
2qw034Z4-chlorobenzoyl CoA ligase/0.451
2vw5BC6ATP-dependent molecular chaperone HSP82/0.451
3b6zCO7Enoyl reductase LovC10.451
3d1yROCGag-Pol polyprotein3.4.23.160.451
3d84NDPDihydrofolate reductase1.5.1.30.451
3ojxFMNNADPH--cytochrome P450 reductase/0.451
3own3OWRenin3.4.23.150.451
4b42942Glucose-1-phosphate thymidylyltransferase/0.451
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4h3zSAHtRNA (guanine-N(1)-)-methyltransferase/0.451
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
4mcb21WtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.451
4xj43ATCyclic GMP-AMP synthase/0.451
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1pd9CO4Dihydrofolate reductase1.5.1.30.450
1ptjNAPNAD(P) transhydrogenase subunit beta1.6.1.20.450
1ra3MTXDihydrofolate reductase1.5.1.30.450
1rneC60Renin3.4.23.150.450
1yc34BCHeat shock protein HSP 90-alpha/0.450
2a87FADThioredoxin reductase1.8.1.90.450
2fy5SOPCholine O-acetyltransferase2.3.1.60.450
2g1o2IGRenin3.4.23.150.450
2jcxNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.450
3c212BADNA integrity scanning protein DisA/0.450
4b4vL34Bifunctional protein FolD/0.450
4f3xNADPutative aldehyde dehydrogenase/0.450
4pvdNDPNADPH-dependent methylglyoxal reductase GRE2/0.450
5e8wSTUTGF-beta receptor type-12.7.11.300.450
5ej5TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.450
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.449
1tv8SAMGTP 3',8-cyclase4.1.99.180.449
2ejvNADL-threonine 3-dehydrogenase/0.449
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.449
3a3gDLZLumazine protein/0.449
3ijoB4DGlutamate receptor 2/0.449
3oqfS51Renin3.4.23.150.449
3oqkS52Renin3.4.23.150.449
3vswR31Renin3.4.23.150.449
4b69FADL-ornithine N(5)-monooxygenase/0.449
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.449
4ek1CAMCamphor 5-monooxygenase1.14.15.10.449
4hgs15GCasein kinase I isoform gamma-32.7.11.10.449
4l4fCAMCamphor 5-monooxygenase1.14.15.10.449
4rcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.449
5ejaTD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.449
1bk0ACVIsopenicillin N synthase1.21.3.10.448
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.448
1yrcCAMCamphor 5-monooxygenase1.14.15.10.448
2bxmIMNSerum albumin/0.448
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.448
2g226IGRenin3.4.23.150.448
2i7pACOPantothenate kinase 32.7.1.330.448
2j08IRFDeoxyribodipyrimidine photo-lyase4.1.99.30.448
2ovhAS0Progesterone receptor/0.448
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.448
3atzFMNProstaglandin F2a synthase/0.448
3b895GP16S rRNA methylase/0.448
3gw9VNILanosterol 14-alpha-demethylase/0.448
3lb8FADPutidaredoxin reductase1.18.1.50.448
3t3r9PLCytochrome P450 2A61.14.130.448
4b79NADProbable short-chain dehydrogenase/0.448
4jx1CAHCamphor 5-monooxygenase1.14.15.10.448
4z38FMNMlnA/0.448
1a8pFADFerredoxin--NADP reductase/0.447
1cf3FADGlucose oxidase1.1.3.40.447
1g6kNADGlucose 1-dehydrogenase1.1.1.470.447
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
1q45FMN12-oxophytodienoate reductase 31.3.1.420.447
1r2jFADFkbI/0.447
1u3dFADCryptochrome-1/0.447
1wntNAPL-xylulose reductase1.1.1.100.447
2il2LIXRenin3.4.23.150.447
2z0ySAMRibosomal RNA small subunit methyltransferase E/0.447
3gcnTYR_GLN_PHESerine endoprotease DegS3.4.21.1070.447
3kpkFADSulfide-quinone reductase/0.447
3lm9ADPPutative fructokinase2.7.1.40.447
3qpvADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.447
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.447
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.447
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.447
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.447
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
1culFOKAdenylate cyclase type 2/0.446
1culFOKAdenylate cyclase type 5/0.446
1dirNADDihydropteridine reductase1.5.1.340.446
1jioDEB6-deoxyerythronolide B hydroxylase/0.446
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1mxiSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.446
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.446
1t2bCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.446
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.446
2a1mCAMCamphor 5-monooxygenase1.14.15.10.446
2abbFMNPentaerythritol tetranitrate reductase/0.446
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
2eglSAHDiphthine synthase/0.446
2owfSAHDiphthine synthase/0.446
2zuiCAMCamphor 5-monooxygenase1.14.15.10.446
3k4nFADPyranose 2-oxidase/0.446
3oixFMNDihydroorotate dehydrogenase/0.446
3ol5SAWCamphor 5-monooxygenase1.14.15.10.446
3own3OXRenin3.4.23.150.446
3p8iFMNPentaerythritol tetranitrate reductase/0.446
4g6gFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.446
4i1iNADMalate dehydrogenase/0.446
4j55031Gag-Pol polyprotein3.4.23.160.446
4looSB4Mitogen-activated protein kinase 14/0.446
4pzkSAHPutative tRNA (cytidine(34)-2'-O)-methyltransferase/0.446
5ifiPRXAcetyl-coenzyme A synthetase/0.446
1dhfFOLDihydrofolate reductase1.5.1.30.445
1gcoNADGlucose 1-dehydrogenase1.1.1.470.445
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.445
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.445
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.445
1phgMYTCamphor 5-monooxygenase1.14.15.10.445
1t85CAMCamphor 5-monooxygenase1.14.15.10.445
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2a1nCAMCamphor 5-monooxygenase1.14.15.10.445
2cv2GSUGlutamate--tRNA ligase6.1.1.170.445
2fznFADBifunctional protein PutA1.5.5.20.445
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.445
2ohjFMNType A flavoprotein FprA10.445
2uxpCLMHTH-type transcriptional regulator TtgR/0.445
2uxuNARHTH-type transcriptional regulator TtgR/0.445
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.445
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.445
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.445
3a4vNADNDP-sugar epimerase/0.445
3lgxATPD-alanine--poly(phosphoribitol) ligase subunit 1/0.445
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.445
3phiNDPShikimate dehydrogenase (NADP(+))/0.445
3tifADPUncharacterized ABC transporter ATP-binding protein MJ0796/0.445
3zkyWT4Isopenicillin N synthase1.21.3.10.445
4b64FADL-ornithine N(5)-monooxygenase/0.445
4nbwNADShort-chain dehydrogenase/reductase SDR/0.445
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.445
1jipKTN6-deoxyerythronolide B hydroxylase/0.444
1ma0NADAlcohol dehydrogenase class-31.1.1.10.444
1p0pBCHCholinesterase3.1.1.80.444
1ualSAHtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.444
1v35NAIEnoyl-ACP reductase/0.444
2af3COAPhosphate acetyltransferase2.3.1.80.444
2ed5SAHDiphthine synthase/0.444
2hfuMEVMevalonate kinase/0.444
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.444
2iko7IGRenin3.4.23.150.444
2y0mACOHistone acetyltransferase KAT8/0.444
2zshGA3Gibberellin receptor GID1A30.444
3bnkFMNFlavoredoxin/0.444
3n4kSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.444
3nk7SAM23S rRNA (adenosine(1067)-2'-O)-methyltransferase/0.444
3v2uATPProtein GAL3/0.444
3vdqNAD3-hydroxybutyrate dehydrogenase/0.444
3w8eNAD3-hydroxybutyrate dehydrogenase/0.444
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.444
4ebfNADPhosphonate dehydrogenase1.20.1.10.444
4g7gVFVLanosterol 14-alpha-demethylase/0.444
4j5j478Gag-Pol polyprotein3.4.23.160.444
4kgkGTPUncharacterized protein/0.444
5bqfNAPProbable hydroxyacid dehydrogenase protein/0.444
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
5ej6TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.444
5emhNAPIridoid synthase1.3.1.990.444
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.444
1bw9NADPhenylalanine dehydrogenase/0.443
1dr3TAPDihydrofolate reductase1.5.1.30.443
1drhNAPDihydrofolate reductase1.5.1.30.443
1me6IVSPlasmepsin-23.4.23.390.443
1nvtNAPShikimate dehydrogenase (NADP(+))/0.443
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.443
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.443
1w51L01Beta-secretase 13.4.23.460.443
2b53D23Cyclin-dependent kinase 22.7.11.220.443
2bz5AB4Heat shock protein HSP 90-alpha/0.443
2e83FMNFMN-binding protein/0.443
2g1r3IGRenin3.4.23.150.443
2i4qUA4Renin3.4.23.150.443
2jb4A14Isopenicillin N synthase1.21.3.10.443
2wb2FADRE11660p/0.443
2zcvNDPQuinone oxidoreductase 21.6.5.20.443
3bg7FADPyranose 2-oxidase/0.443
3bmoNAPPteridine reductase/0.443
3c9sACPThiamine-monophosphate kinase/0.443
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.443
3pw8ACO1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.443
3wrmCAMCamphor 5-monooxygenase1.14.15.10.443
4a862ANMajor pollen allergen Bet v 1-A/0.443
4asuADPATP synthase subunit alpha, mitochondrial/0.443
4dpuAGSMevalonate diphosphate decarboxylase/0.443
4f081RSTyrosine-protein kinase JAK2/0.443
4fuj1U9Urokinase-type plasminogen activator3.4.21.730.443
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.443
4l4cCAMCamphor 5-monooxygenase1.14.15.10.443
4nvk2NYPeroxidase/0.443
4r1lADPPhenylacetate-coenzyme A ligase/0.443
4ypuSAMHistone-lysine N-methyltransferase ASH1L2.1.1.430.443
5bsgNAPPyrroline-5-carboxylate reductase/0.443
5cp4CAMCamphor 5-monooxygenase1.14.15.10.443
1cl0FADThioredoxin reductase1.8.1.90.442
1honGNHAdenylosuccinate synthetase/0.442
1jd0AZMCarbonic anhydrase 124.2.1.10.442
1l4mNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.442
1lbcCYZGlutamate receptor 2/0.442
1lldNADL-lactate dehydrogenase 21.1.1.270.442
1nm5NAPNAD(P) transhydrogenase subunit beta1.6.1.20.442
1z69F425,10-methylenetetrahydromethanopterin reductase/0.442
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.442
2aquDR7Gag-Pol polyprotein3.4.23.160.442
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.442
2cy0NAPShikimate dehydrogenase (NADP(+))/0.442
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.442
2f3rG5PGuanylate kinase2.7.4.80.442
2gv8NDPThiol-specific monooxygenase1.14.130.442
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.442
2oa1FADFlavin-dependent tryptophan halogenase RebH1.14.19.90.442
2oapANPType II secretion system protein (GspE-2)/0.442
2oegUPGUDP-glucose pyrophosphorylase/0.442
2qbuSAHPrecorrin-2 methyltransferase/0.442
2y4gTIRTamL/0.442
3a0tADPSensor histidine kinase/0.442
3a1nNADNDP-sugar epimerase/0.442
3ig6438Urokinase-type plasminogen activator3.4.21.730.442
3k5c0BIBeta-secretase 13.4.23.460.442
3p67FMNPentaerythritol tetranitrate reductase/0.442
3uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
3vsxR32Renin3.4.23.150.442
4a6nFADTetX family tetracycline inactivation enzyme/0.442
4aa4QC0Mitogen-activated protein kinase 14/0.442
4bfvZVVPantothenate kinase2.7.1.330.442
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.442
4hs4FMNChromate reductase/0.442
4i0j842Beta-secretase 13.4.23.460.442
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.442
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.442
4v2gITCTetracycline repressor protein class D/0.442
5hg0SAMPantothenate synthetase/0.442
5jlaNADPutative short-chain dehydrogenase/reductase/0.442
1bygSTUTyrosine-protein kinase CSK/0.441
1g4tFTPThiamine-phosphate synthase/0.441
1ivp1ZKGag-Pol polyprotein/0.441
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.441
1wngSAHDiphthine synthase/0.441
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.441
2ie0ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2m56CAMCamphor 5-monooxygenase1.14.15.10.441
2o12FMNChorismate synthase/0.441
2ojj82AMitogen-activated protein kinase 12.7.11.240.441
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.441
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2w3bNDPDihydrofolate reductase1.5.1.30.441
3aw9GDUNAD-dependent epimerase/dehydratase/0.441
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.441
3ey9TDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.441
3gegNADShort-chain dehydrogenase/reductase SDR/0.441
3p3zP3ZPutative cytochrome P450/0.441
3t2kFADSulfide-quinone reductase/0.441
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.441
4enhFVXCholesterol 24-hydroxylase/0.441
4eo3FMNBacterioferritin comigratory protein/NADH dehydrogenase/0.441
4jldADPAdenylate kinase/0.441
4m2bUPGUDP-glucose pyrophosphorylase/0.441
4qi7FADCellobiose dehydrogenase/0.441
1adfTADAlcohol dehydrogenase E chain1.1.1.10.440
1cnfFADNitrate reductase [NADH]1.7.1.10.440
1d3dBZTProthrombin3.4.21.50.440
1fmjRTLRetinol dehydratase/0.440
1hopGCPAdenylosuccinate synthetase/0.440
1jmhUMPThymidylate synthase/0.440
1udaUFGUDP-glucose 4-epimerase5.1.3.20.440
1zptFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.440
2fj1CTCTetracycline repressor protein class D/0.440
2ghlLIBMitogen-activated protein kinase 14/0.440
2hk9NAPShikimate dehydrogenase (NADP(+))/0.440
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2vwqNAPGlucose 1-dehydrogenase/0.440
2znnS44Peroxisome proliferator-activated receptor alpha/0.440
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.440
2zz0FADThioredoxin reductase 1, cytoplasmic1.8.1.90.440
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.440
3oeeANPATP synthase subunit alpha, mitochondrial/0.440
3oeeANPATP synthase subunit beta, mitochondrial3.6.3.140.440
3rasNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.440
3ru7NADUDP-N-acetylglucosamine 4-epimerase/0.440
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.440
3vvpBNUUncharacterized protein/0.440
4a61ANPPlasmid segregation protein ParM/0.440
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4araC56Acetylcholinesterase3.1.1.70.440
4bb3KKAIsopenicillin N synthase1.21.3.10.440
4bmpFMNProtein NrdI/0.440
4c4oNADSADH/0.440
4du82P0Mevalonate diphosphate decarboxylase/0.440
4ei7GDPPlasmid replication protein RepX/0.440
4jia1K3Tyrosine-protein kinase JAK2/0.440
4kne1CYDihydrofolate reductase1.5.1.30.440
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.440
4tm0FADKtzI/0.440
4xguADPPutative pachytene checkpoint protein 2/0.440