sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 1.000 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.608 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.585 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.506 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.506 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.501 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.500 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.500 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.495 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.494 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.493 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.493 | |
| 3cxh | SMA | Cytochrome b | / | 0.491 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.491 | |
| 1osv | CHC | Bile acid receptor | / | 0.490 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.489 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.488 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.488 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.487 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.487 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.486 | |
| 1ezv | SMA | Cytochrome b | / | 0.485 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.485 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.485 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.485 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.483 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.483 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.483 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.483 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.483 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.482 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.482 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.482 | |
| 4at5 | MUJ | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.482 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.482 | |
| 1kb9 | SMA | Cytochrome b | / | 0.481 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.481 | |
| 3cx5 | SMA | Cytochrome b | / | 0.481 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.481 | |
| 4iae | 1DX | Alr2278 protein | / | 0.481 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.480 | |
| 1kyo | SMA | Cytochrome b | / | 0.479 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.479 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.479 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.479 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.478 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.478 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.477 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.477 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.476 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.475 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.475 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.475 | |
| 4iah | 1DX | Alr2278 protein | / | 0.474 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.474 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.473 | |
| 2oye | IM8 | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.473 | |
| 2qjy | SMA | Cytochrome b | / | 0.473 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.473 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.473 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.473 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.472 | |
| 3h1j | SMA | Cytochrome b | / | 0.472 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.472 | |
| 4aa0 | AA0 | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 1tw2 | ERT | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.471 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 2d3m | COA | 5,7-dihydroxy-2-methylchromone synthase | 2.3.1.216 | 0.471 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.471 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.471 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.471 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.470 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.470 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.470 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.470 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.469 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.469 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.469 | |
| 2y03 | Y01 | Beta-1 adrenergic receptor | / | 0.469 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.469 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.469 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.469 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.469 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.469 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.469 | |
| 2wle | COA | Polysialic acid O-acetyltransferase | / | 0.468 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.468 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.468 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.468 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.468 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.467 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 3kq7 | KQ7 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.467 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.467 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.467 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.467 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.467 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.466 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.466 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 3ffi | 3OB | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.466 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.466 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.466 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.466 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.465 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.465 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.465 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.465 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.465 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.465 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.465 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.465 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.465 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.465 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.464 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.464 | |
| 1ysx | 4EB | Serum albumin | / | 0.464 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 2y02 | Y01 | Beta-1 adrenergic receptor | / | 0.464 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.464 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.464 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.464 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.464 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.464 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.464 | |
| 4irn | FAD | AnaB | / | 0.464 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.463 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.463 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.463 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.463 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.463 | |
| 2y00 | Y01 | Beta-1 adrenergic receptor | / | 0.463 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.463 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.463 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.463 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.463 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.463 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.463 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.463 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.463 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.463 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.463 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.462 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.462 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.462 | |
| 2y5k | YCU | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.462 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.462 | |
| 4jtz | 1NW | Genome polyprotein | 2.7.7.48 | 0.462 | |
| 2c6h | PXI | Cytochrome P450 monooxygenase PikC | / | 0.461 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.461 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.461 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.461 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.461 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.461 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.461 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.460 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 2c0i | L1G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.460 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.460 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.460 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.460 | |
| 3gob | HXX | DdmC | / | 0.460 | |
| 3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3p3e | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.460 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.460 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.460 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.460 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.460 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.460 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.459 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.459 | |
| 1ppj | SMA | Cytochrome b | / | 0.459 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.459 | |
| 2apg | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.459 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.459 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.459 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.459 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.459 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.459 | |
| 2yiu | SMA | Cytochrome b | / | 0.459 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.459 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.459 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.459 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.459 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.459 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.459 | |
| 4hee | 14R | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.459 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.459 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.459 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.458 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.458 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 2d52 | COA | 5,7-dihydroxy-2-methylchromone synthase | 2.3.1.216 | 0.458 | |
| 3aba | FLI | Cytochrome P450 | / | 0.458 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.458 | |
| 3kdu | NKS | Peroxisome proliferator-activated receptor alpha | / | 0.458 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.458 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.458 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.458 | |
| 4fog | C2F | Thymidylate synthase ThyA | / | 0.458 | |
| 4h1m | 0YJ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.458 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.458 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.458 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.457 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 1ppj | ANY | Cytochrome b | / | 0.457 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.457 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.457 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.457 | |
| 3m8q | DJZ | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.457 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.457 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.457 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.457 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.457 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.456 | |
| 1tqm | ANP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.456 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.456 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3eql | MXP | DNA-directed RNA polymerase subunit beta | / | 0.456 | |
| 3eql | MXP | DNA-directed RNA polymerase subunit beta' | / | 0.456 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.456 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.456 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 3zuy | TCH | Transporter | / | 0.456 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.456 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.456 | |
| 4l9q | 9TP | Serum albumin | / | 0.456 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.456 | |
| 1c6y | MK1 | Protease | / | 0.455 | |
| 1pp9 | SMA | Cytochrome b | / | 0.455 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.455 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.455 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.455 | |
| 3rus | ADP | Chaperonin | / | 0.455 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.455 | |
| 4n6b | COA | Uncharacterized protein | / | 0.455 | |
| 4qgi | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.455 | |
| 1kgj | FL8 | Transthyretin | / | 0.454 | |
| 1nav | IH5 | Thyroid hormone receptor alpha | / | 0.454 | |
| 1owl | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.454 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.454 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.454 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.454 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.454 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.454 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.454 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.454 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.454 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.454 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.454 | |
| 4fnd | 3H9 | Enoyl-CoA hydratase | / | 0.454 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.453 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.453 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2iog | IOG | Estrogen receptor | / | 0.453 | |
| 2j5n | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.453 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.453 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.453 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.453 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.453 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.453 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.453 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.453 | |
| 3wec | AUI | Cytochrome P450 | / | 0.453 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.453 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.453 | |
| 4gmg | NAP | Yersiniabactin biosynthetic protein YbtU | / | 0.453 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.453 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.453 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.453 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.453 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.452 | |
| 1kqg | HQO | Formate dehydrogenase, nitrate-inducible, cytochrome b556(Fdn) subunit | / | 0.452 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.452 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.452 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.452 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.452 | |
| 2qjp | SMA | Cytochrome b | / | 0.452 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.452 | |
| 3cgd | NAD | Coenzyme A disulfide reductase | / | 0.452 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.452 | |
| 3glm | COO | Glutaconyl-CoA decarboxylase alpha subunit | / | 0.452 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.452 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.452 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.452 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.452 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.452 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 alpha chain | / | 0.451 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 beta chain | / | 0.451 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.451 | |
| 2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.451 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2ijg | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.451 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.451 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.451 | |
| 3bej | MUF | Bile acid receptor | / | 0.451 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.451 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.451 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.451 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.451 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.451 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.451 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.451 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.451 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.450 | |
| 1gqt | ACP | Ribokinase | / | 0.450 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.450 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.450 | |
| 2q6s | PLB | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.450 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.450 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.450 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.450 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.450 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.450 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.450 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.450 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.450 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.450 | |
| 5ag6 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.450 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.449 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.449 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.449 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.449 | |
| 2go4 | TUX | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.449 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2xir | 00J | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.449 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.449 | |
| 3efl | 706 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.449 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.449 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.449 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.449 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.449 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.449 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.449 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.449 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.449 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.449 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1wrl | TFP | Troponin C, slow skeletal and cardiac muscles | / | 0.448 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.448 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.448 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.448 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.448 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 4eo8 | 0S3 | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.448 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.448 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.447 | |
| 1jut | LYD | Thymidylate synthase | / | 0.447 | |
| 1kyz | FER | Caffeic acid 3-O-methyltransferase | 2.1.1.68 | 0.447 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.447 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.447 | |
| 2gek | GDP | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.447 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.447 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.447 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.447 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3liv | E16 | Protease | / | 0.447 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.447 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.447 | |
| 5ca1 | NZO | Tubulin beta-2 chain | / | 0.447 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.446 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 1xqc | AEJ | Estrogen receptor | / | 0.446 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.446 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.446 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.446 | |
| 3bhl | THG | Thymidylate synthase | / | 0.446 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.446 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 3vnt | 0JA | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.446 | |
| 4agu | D15 | Cyclin-dependent kinase-like 1 | / | 0.446 | |
| 4crs | AGS | Serine/threonine-protein kinase N2 | 2.7.11.13 | 0.446 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.446 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.446 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.446 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.446 | |
| 4ig0 | 1FG | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.446 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 5a27 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1nva | ADP | Pentafunctional AROM polypeptide | / | 0.445 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 2dqs | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.445 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 2y01 | Y01 | Beta-1 adrenergic receptor | / | 0.445 | |
| 3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.445 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.445 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.445 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.445 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 3wxy | COA | Uncharacterized protein | / | 0.445 | |
| 4af3 | VX6 | Aurora kinase B | 2.7.11.1 | 0.445 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.445 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.445 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.445 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.445 | |
| 4y8v | ADP | Acyl-CoA synthetase (NDP forming) | / | 0.445 | |
| 4ykg | NAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.445 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.445 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1tqp | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.444 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.444 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.444 | |
| 2k62 | ITL | Fatty acid-binding protein, liver | / | 0.444 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.444 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.444 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.444 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.444 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 3up0 | D7S | aceDAF-12 | / | 0.444 | |
| 3zux | TCH | Transporter | / | 0.444 | |
| 4ase | AV9 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.444 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.444 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.444 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.444 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.444 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.444 | |
| 1brp | RTL | Retinol-binding protein 4 | / | 0.443 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.443 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.443 | |
| 2bl4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.443 | |
| 2e1t | MLC | Anthocyanin malonyltransferase homolog | / | 0.443 | |
| 2f1k | NAP | Prephenate dehydrogenase | / | 0.443 | |
| 2ibt | NEA | Modification methylase TaqI | 2.1.1.72 | 0.443 | |
| 2jj1 | PIT | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 2jj1 | PIT | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 2jj1 | PIT | ATP synthase subunit gamma, mitochondrial | / | 0.443 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.443 | |
| 2wq6 | FAD | RE11660p | / | 0.443 | |
| 2wug | HPK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.443 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.443 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.443 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.443 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.443 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.443 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.443 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.443 | |
| 4ez7 | 2AN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.443 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4wq4 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.443 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.442 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.442 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.442 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.442 | |
| 2bx8 | AZQ | Serum albumin | / | 0.442 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.442 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.442 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.442 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 2ibz | SMA | Cytochrome b | / | 0.442 | |
| 2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.442 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.442 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.442 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.442 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.442 | |
| 4eyj | N61 | Mitogen-activated protein kinase 13 | 2.7.11.24 | 0.442 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.442 | |
| 4lcf | 1WL | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.442 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.442 | |
| 5ag7 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.442 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.441 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.441 | |
| 1o1v | TCH | Gastrotropin | / | 0.441 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.441 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 2qu6 | 857 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.441 | |
| 3iw8 | HIZ | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.441 | |
| 3r32 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.441 | |
| 3sh0 | SAX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 3vs1 | VSA | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.441 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.441 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.441 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.441 | |
| 4j98 | ACP | Fibroblast growth factor receptor 2 | / | 0.441 | |
| 4ozn | ATP | Ammonium transporter | / | 0.441 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.441 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1kk4 | ACO | Streptogramin A acetyltransferase | 2.3.1 | 0.440 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.440 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.440 | |
| 1sn5 | T3 | Transthyretin | / | 0.440 | |
| 1tez | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.440 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.440 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.440 | |
| 2jiz | STL | ATP synthase subunit alpha, mitochondrial | / | 0.440 | |
| 2jiz | STL | ATP synthase subunit gamma, mitochondrial | / | 0.440 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.440 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.440 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.440 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.440 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.440 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.440 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.440 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.440 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.440 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 4a0m | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 | 0.440 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.440 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.440 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.440 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.440 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.440 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.440 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.440 |