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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4jq7KJQEpidermal growth factor receptor2.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4jq7KJQEpidermal growth factor receptor2.7.10.11.000
4jr3KJREpidermal growth factor receptor2.7.10.10.672
4jq8KJ8Epidermal growth factor receptor2.7.10.10.645
4jrvKJVEpidermal growth factor receptor2.7.10.10.645
1m17AQ4Epidermal growth factor receptor2.7.10.10.626
2itnANPEpidermal growth factor receptor2.7.10.10.618
2itpAEEEpidermal growth factor receptor2.7.10.10.607
2itvANPEpidermal growth factor receptor2.7.10.10.589
2eb3ANPEpidermal growth factor receptor2.7.10.10.580
4i231C9Epidermal growth factor receptor2.7.10.10.576
4riyADPEpidermal growth factor receptor2.7.10.10.576
2itwITQEpidermal growth factor receptor2.7.10.10.575
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.569
2ittAEEEpidermal growth factor receptor2.7.10.10.567
2itxANPEpidermal growth factor receptor2.7.10.10.567
4wkqIREEpidermal growth factor receptor2.7.10.10.564
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.555
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.554
3vjoANPEpidermal growth factor receptor2.7.10.10.554
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.554
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.550
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.549
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.542
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.537
4gk3L87Ephrin type-A receptor 32.7.10.10.537
2of2547Tyrosine-protein kinase Lck2.7.10.20.536
2hk51BMTyrosine-protein kinase HCK2.7.10.20.535
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.530
4hjoAQ4Epidermal growth factor receptor2.7.10.10.529
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.528
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.526
3w33W19Epidermal growth factor receptor2.7.10.10.526
3ac2KSETyrosine-protein kinase Lck2.7.10.20.525
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.523
2y6o1N1Ephrin type-A receptor 42.7.10.10.521
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.520
2of4979Tyrosine-protein kinase Lck2.7.10.20.519
4c02TAKActivin receptor type-12.7.11.300.519
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.516
2gs7ANPEpidermal growth factor receptor2.7.10.10.516
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.515
3vs3VSETyrosine-protein kinase HCK2.7.10.20.515
1py5PY1TGF-beta receptor type-12.7.11.300.513
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.513
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.513
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.511
2xyuQ9GEphrin type-A receptor 42.7.10.10.511
1xkkFMMEpidermal growth factor receptor2.7.10.10.510
1vjy460TGF-beta receptor type-12.7.11.300.509
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.509
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.509
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.509
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.508
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.508
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.508
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.508
4i22IREEpidermal growth factor receptor2.7.10.10.508
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.507
2vwu7X1Ephrin type-B receptor 42.7.10.10.507
2vwx7X4Ephrin type-B receptor 42.7.10.10.507
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.507
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.507
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.504
2ituITQEpidermal growth factor receptor2.7.10.10.503
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.503
3uvp048Mitogen-activated protein kinase 14/0.503
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.502
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.501
3w2sW2REpidermal growth factor receptor2.7.10.10.501
2itqITQEpidermal growth factor receptor2.7.10.10.499
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.499
4bb432WEphrin type-B receptor 42.7.10.10.498
4g2fC07Ephrin type-A receptor 32.7.10.10.498
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.498
2xvdAS6Ephrin type-B receptor 42.7.10.10.494
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.494
2c475IDCasein kinase I isoform gamma-2/0.493
2qo9ANPEphrin type-A receptor 32.7.10.10.493
4gk4L90Ephrin type-A receptor 32.7.10.10.493
3poz03PEpidermal growth factor receptor2.7.10.10.492
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.492
3w2rW2REpidermal growth factor receptor2.7.10.10.492
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.491
3acjKSSTyrosine-protein kinase Lck2.7.10.20.491
3uvqFS8Mitogen-activated protein kinase 14/0.491
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.490
1bygSTUTyrosine-protein kinase CSK/0.489
3dt1P40Mitogen-activated protein kinase 14/0.489
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.489
1u4dDBQActivated CDC42 kinase 1/0.487
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.487
3w32W32Epidermal growth factor receptor2.7.10.10.487
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.487
2io6330Wee1-like protein kinase2.7.10.20.486
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.486
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.486
1u54ACPActivated CDC42 kinase 1/0.485
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.484
4id71G0Activated CDC42 kinase 1/0.484
5cnnANPEpidermal growth factor receptor2.7.10.10.484
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.483
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.483
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.483
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.482
5e8wSTUTGF-beta receptor type-12.7.11.300.482
2itzIREEpidermal growth factor receptor2.7.10.10.481
2qoqANPEphrin type-A receptor 32.7.10.10.481
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.481
4gk2L66Ephrin type-A receptor 32.7.10.10.481
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.481
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.481
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.480
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.479
4j97ACPFibroblast growth factor receptor 2/0.479
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.478
4fob0USALK tyrosine kinase receptor2.7.10.10.478
4kb81QOCasein kinase I isoform delta2.7.11.10.478
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.477
2vwz7X6Ephrin type-B receptor 42.7.10.10.477
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.477
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.477
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.477
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.476
2i0ePDSProtein kinase C beta type2.7.11.130.476
3vryB43Tyrosine-protein kinase HCK2.7.10.20.476
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.475
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.475
1jpaANPEphrin type-B receptor 22.7.10.10.474
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.474
1agwSU2Fibroblast growth factor receptor 1/0.473
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.473
2balPQAMitogen-activated protein kinase 14/0.473
2j7t274Serine/threonine-protein kinase 102.7.11.10.473
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.473
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.473
4aa5NQBMitogen-activated protein kinase 14/0.473
4kba1QMCasein kinase I isoform delta2.7.11.10.473
5e8xSTUTGF-beta receptor type-12.7.11.300.473
3hmm855TGF-beta receptor type-12.7.11.300.472
4u7wNDPMxaA/0.472
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.471
2vwy7X5Ephrin type-B receptor 42.7.10.10.470
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.470
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.469
2wotZZGTGF-beta receptor type-12.7.11.300.469
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.469
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.468
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.468
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.468
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.468
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.468
4c62XWWTyrosine-protein kinase JAK2/0.468
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.468
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
2p5uNADUDP-glucose 4-epimerase/0.467
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.467
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.467
4qnaX11Serine/threonine-protein kinase 242.7.11.10.467
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.466
2rg5279Mitogen-activated protein kinase 14/0.466
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.466
2zybKSLTyrosine-protein kinase Lck2.7.10.20.466
3fklFKLMitogen-activated protein kinase 14/0.466
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.466
4appN53Serine/threonine-protein kinase PAK 42.7.11.10.466
4fyn0VETyrosine-protein kinase SYK2.7.10.20.466
4nks2M2Fibroblast growth factor receptor 1/0.466
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.466
1bwsNDPGDP-L-fucose synthase/0.465
1rw8580TGF-beta receptor type-12.7.11.300.465
2wouZZFTGF-beta receptor type-12.7.11.300.465
3zh8C58Protein kinase C iota type2.7.11.130.465
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.465
4kbc1QJCasein kinase I isoform delta2.7.11.10.465
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.465
1psa0ZLPepsin A3.4.23.10.464
3gc9B45Mitogen-activated protein kinase 112.7.11.240.464
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.464
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.464
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.463
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.463
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
3mpt1GKMitogen-activated protein kinase 14/0.463
4wboANWRhodopsin kinase/0.463
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.463
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.463
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.462
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.462
3s4qNK0Mitogen-activated protein kinase 14/0.462
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.462
4nka2K7Fibroblast growth factor receptor 1/0.462
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
3flwFLWMitogen-activated protein kinase 14/0.461
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.461
3vs1VSATyrosine-protein kinase HCK2.7.10.20.461
4kiq1RAMitogen-activated protein kinase 14/0.461
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.461
1di9MSQMitogen-activated protein kinase 14/0.460
2henADPEphrin type-B receptor 22.7.10.10.460
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.460
4fz60VGTyrosine-protein kinase SYK2.7.10.20.460
4kb81QNCasein kinase I isoform delta2.7.11.10.460
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.460
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
3gxlQIGTGF-beta receptor type-12.7.11.300.459
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.458
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.458
2vww7X2Ephrin type-B receptor 42.7.10.10.458
3gbuATPUncharacterized sugar kinase PH14592.7.10.458
3gubGUBDeath-associated protein kinase 12.7.11.10.458
3tucFPWTyrosine-protein kinase SYK2.7.10.20.458
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.458
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.458
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.457
2izrBRKCasein kinase I isoform gamma-32.7.11.10.457
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3biz61EWee1-like protein kinase2.7.10.20.457
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.457
3s1dZIRCytokinin dehydrogenase 11.5.99.120.457
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.457
1di8DTQCyclin-dependent kinase 22.7.11.220.456
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.456
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.456
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.456
3iw4LW4Protein kinase C alpha type2.7.11.130.456
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.456
4hgt15GCasein kinase I isoform delta2.7.11.10.456
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.456
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.456
2jedLG8Protein kinase C theta type2.7.11.130.455
3btjDEQHTH-type transcriptional regulator QacR/0.455
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.455
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.455
4c58824Cyclin-G-associated kinase2.7.11.10.455
4xwtU5PRibonuclease J/0.455
5aacVGHALK tyrosine kinase receptor2.7.10.10.455
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.454
2vttLZDCyclin-dependent kinase 22.7.11.220.454
3hz5Z64Heat shock protein HSP 90-alpha/0.454
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.454
3s2pPMUCyclin-dependent kinase 22.7.11.220.454
3u9eCOALmo1369 protein/0.454
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.454
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2znq401Peroxisome proliferator-activated receptor delta/0.453
3uyt0CKCasein kinase I isoform delta2.7.11.10.453
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.453
4fnzNZFALK tyrosine kinase receptor2.7.10.10.453
4h9506UDihydrofolate reductase1.5.1.30.453
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.453
5iubCLRAdenosine receptor A2a/0.453
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
1ouk084Mitogen-activated protein kinase 14/0.452
1y0s331Peroxisome proliferator-activated receptor delta/0.452
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.452
2hasC3OVitamin D3 receptor/0.452
2vn0TDZCytochrome P450 2C8/0.452
3ac1KZITyrosine-protein kinase Lck2.7.10.20.452
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.452
3fln3FNMitogen-activated protein kinase 14/0.452
4ckjADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.452
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.452
4kbk1QGCasein kinase I isoform delta2.7.11.10.452
5a3bAPRSIR2 family protein/0.452
1bsvNDPGDP-L-fucose synthase/0.451
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
2hog710Serine/threonine-protein kinase Chk12.7.11.10.451
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.451
3cr0809Wee1-like protein kinase2.7.10.20.451
3el4ROCGag-Pol polyprotein3.4.23.160.451
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3vt7VDXVitamin D3 receptor/0.451
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.451
1gii1PUCyclin-dependent kinase 22.7.11.220.450
2in6839Wee1-like protein kinase2.7.10.20.450
2x9fX9FEphrin type-B receptor 42.7.10.10.450
3dds26BGlycogen phosphorylase, liver form2.4.1.10.450
4aacAAVMitogen-activated protein kinase 14/0.450
4btkDTQTau-tubulin kinase 12.7.11.10.450
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.450
4dymIYZActivin receptor type-12.7.11.300.450
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.450
4kin1M8Mitogen-activated protein kinase 14/0.450
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.450
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.450
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.450
2izt23DCasein kinase I isoform gamma-32.7.11.10.449
2qocANPEphrin type-A receptor 32.7.10.10.449
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.449
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.449
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.449
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.449
3a783EVVitamin D3 receptor/0.449
4djaFAD(6-4) photolyase/0.449
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.449
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.449
4hvh19RTyrosine-protein kinase JAK32.7.10.20.449
1p0hACOMycothiol acetyltransferase2.3.1.1890.448
1ywrLI9Mitogen-activated protein kinase 14/0.448
1zz2B11Mitogen-activated protein kinase 14/0.448
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.448
2py3ACPFibroblast growth factor receptor 2/0.448
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.448
3a62STURibosomal protein S6 kinase beta-12.7.11.10.448
3gfeP37Mitogen-activated protein kinase 14/0.448
3mdvCL6Cholesterol 24-hydroxylase/0.448
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
4ccbOFGALK tyrosine kinase receptor2.7.10.10.448
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.448
4ix6ADPUncharacterized protein/0.448
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.448
1nzdUPGDNA beta-glucosyltransferase/0.447
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.447
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.447
2q9fC3SCholesterol 24-hydroxylase/0.447
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.447
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.447
2z2w770Wee1-like protein kinase2.7.10.20.447
3aidARQGag-Pol polyprotein3.4.23.160.447
3iodA6DPantothenate synthetase6.3.2.10.447
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.447
4f650S9Fibroblast growth factor receptor 1/0.447
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1klkPMDDihydrofolate reductase1.5.1.30.446
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.446
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.446
3fskRO6Mitogen-activated protein kinase 14/0.446
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.446
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.446
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.446
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.445
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
2g2fAGSTyrosine-protein kinase ABL12.7.10.20.445
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.445
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.445
3l8xN4DMitogen-activated protein kinase 14/0.445
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.445
4gt3ATPMitogen-activated protein kinase 12.7.11.240.445
4kkyCAMCamphor 5-monooxygenase1.14.15.10.445
4mgiCMPRap guanine nucleotide exchange factor 4/0.445
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1hfqMOTDihydrofolate reductase1.5.1.30.444
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3gwfFADCyclohexanone monooxygenase/0.444
3oqfS51Renin3.4.23.150.444
3r7eX88Cyclin-dependent kinase 22.7.11.220.444
4fgg0U5Dihydrofolate reductase1.5.1.30.444
4iarERM5-hydroxytryptamine receptor 1B/0.444
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.444
4xhgADPUncharacterized protein/0.444
1fxsNAPGDP-L-fucose synthase/0.443
1t7j478Gag-Pol polyprotein3.4.23.160.443
1u3cFADCryptochrome-1/0.443
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.443
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.443
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.443
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.443
2ghlLIBMitogen-activated protein kinase 14/0.443
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.443
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.443
2pwlACPFibroblast growth factor receptor 2/0.443
2xa4AZ5Tyrosine-protein kinase JAK2/0.443
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.443
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.443
3mtfA3FActivin receptor type-12.7.11.300.443
4aw530KEphrin type-B receptor 42.7.10.10.443
4bbe3O4Tyrosine-protein kinase JAK2/0.443
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.443
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.443
4kf1HT5Aryldialkylphosphatase3.1.8.10.443
5a3cNADSIR2 family protein/0.443
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.442
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.442
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.442
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.442
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.442
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.442
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.442
3gobHXXDdmC/0.442
3i8aN22Dihydrofolate reductase1.5.1.30.442
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3tvuB37Acetyl-CoA carboxylase/0.442
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.442
4c59FEFCyclin-G-associated kinase2.7.11.10.442
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4fz70VHTyrosine-protein kinase SYK2.7.10.20.442
4lopSB4Mitogen-activated protein kinase 14/0.442
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.442
4othDRNSerine/threonine-protein kinase N1/0.442
5aabVGHALK tyrosine kinase receptor2.7.10.10.442
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.442
1h5rTHMGlucose-1-phosphate thymidylyltransferase 1/0.441
1phePIYCamphor 5-monooxygenase1.14.15.10.441
2nq8ZIDEnoyl-ACP reductase/0.441
3mvm39PMitogen-activated protein kinase 14/0.441
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.441
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.441
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.441
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.441
1eh4IC1Casein kinase I homolog 12.7.11.10.440
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.440
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
2b7zMK1Gag-Pol polyprotein/0.440
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.440
2hamC33Vitamin D3 receptor/0.440
2izuP01Casein kinase I isoform gamma-32.7.11.10.440
2pmoHMDProtein kinase 7/0.440
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.440
2qo7ANPEphrin type-A receptor 32.7.10.10.440
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.440
2wipP49Cyclin-dependent kinase 22.7.11.220.440
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.440
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.440
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
3kf7L9GMitogen-activated protein kinase 14/0.440
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.440
3ocgOCGMitogen-activated protein kinase 14/0.440
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.440
3s79ASDAromatase1.14.14.140.440
3wb2YGPUncharacterized protein MJ0488/0.440
3zep1NXTyrosine-protein kinase JAK32.7.10.20.440