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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4j7xSASSepiapterin reductase1.1.1.153

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4j7xSASSepiapterin reductase1.1.1.1531.000
4j7uYTZSepiapterin reductase1.1.1.1530.664
4hwkSFYSepiapterin reductase1.1.1.1530.562
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.528
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.519
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.519
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.518
2ovmAS0Progesterone receptor/0.517
3g8eIS1Nicotinamide phosphoribosyltransferase2.4.2.120.513
4ia1BIVVitamin D3 receptor A/0.513
4ia7BIVVitamin D3 receptor A/0.512
2gpuOHTEstrogen-related receptor gamma/0.511
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.509
3vt7VDXVitamin D3 receptor/0.508
4ia3BIVVitamin D3 receptor A/0.507
2ovhAS0Progesterone receptor/0.506
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.506
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.506
4o281QSNicotinamide phosphoribosyltransferase2.4.2.120.506
3jwm5WBDihydrofolate reductase/0.505
4kfp1R7Nicotinamide phosphoribosyltransferase2.4.2.120.505
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.504
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.504
2hl0A3SThreonine--tRNA ligase6.1.1.30.504
1fmlRTLRetinol dehydratase/0.502
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.501
4a83DXCMajor pollen allergen Bet v 1-A/0.501
1ppjANYCytochrome b/0.499
5hs1VORLanosterol 14-alpha demethylase/0.499
1nhz486Glucocorticoid receptor/0.498
2fzhDH1Dihydrofolate reductase1.5.1.30.498
4m6p20RNicotinamide phosphoribosyltransferase2.4.2.120.498
1dtpAPUDiphtheria toxin/0.496
3cseN22Uncharacterized protein/0.496
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.496
2fszOHTEstrogen receptor beta/0.495
1vj3TABDihydrofolate reductase1.5.1.30.494
2bj4OHTEstrogen receptor/0.494
2fziDH3Dihydrofolate reductase1.5.1.30.494
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.494
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.494
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.494
3qly55VUncharacterized protein/0.493
1dajMOTDihydrofolate reductase1.5.1.30.492
1x8lOXRRetinol dehydratase/0.492
4h9506UDihydrofolate reductase1.5.1.30.492
3p3zP3ZPutative cytochrome P450/0.491
3jwcEKBDihydrofolate reductase/0.490
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.490
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.489
4ia2BIVVitamin D3 receptor A/0.489
4ruoBIVVitamin D3 receptor A/0.489
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.488
3kpzZNEVitamin D3 receptor/0.488
4x5iFOLDihydrofolate reductase1.5.1.30.488
1wsvTHHAminomethyltransferase, mitochondrial/0.487
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.487
3p99LNPLanosterol 14-alpha-demethylase/0.487
1hfqMOTDihydrofolate reductase1.5.1.30.486
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.486
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.486
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.486
3ipq965Oxysterols receptor LXR-alpha/0.486
3qlxQLRUncharacterized protein/0.486
4g1d0VKVitamin D3 receptor A/0.486
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.485
1uy9PU6Heat shock protein HSP 90-alpha/0.485
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.485
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.483
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.483
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.483
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.482
3fwfCAMCamphor 5-monooxygenase1.14.15.10.482
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.482
4nx6FOLDihydrofolate reductase1.5.1.30.482
1klkPMDDihydrofolate reductase1.5.1.30.481
1m13HYFNuclear receptor subfamily 1 group I member 2/0.481
1o5rFR9Adenosine deaminase3.5.4.40.481
1uyhPU0Heat shock protein HSP 90-alpha/0.481
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.481
2p7zOHTEstrogen-related receptor gamma/0.481
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.481
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.481
1errRALEstrogen receptor/0.480
1fmjRTLRetinol dehydratase/0.480
2hasC3OVitamin D3 receptor/0.480
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.480
2qjySMACytochrome b/0.480
3fwjCAMCamphor 5-monooxygenase1.14.15.10.480
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.480
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.480
4h9614QDihydrofolate reductase1.5.1.30.480
1qknRALEstrogen receptor beta/0.479
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
2g0gSP0Peroxisome proliferator-activated receptor gamma/0.479
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.479
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.479
3vtcTK3Vitamin D3 receptor/0.479
3w5q3KLVitamin D3 receptor/0.479
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.479
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.478
2x9dITCTetracycline repressor protein class D/0.478
2yatEEUEstrogen receptor/0.478
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.478
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.478
3h3r14HCollagen type IV alpha-3-binding protein/0.478
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.478
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.478
3u8hBHPPhospholipase A2, membrane associated/0.478
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.478
4iteTEYVitamin D3 receptor/0.478
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.478
1r2jFADFkbI/0.477
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.477
2w8y486Progesterone receptor/0.477
2zlaVDBVitamin D3 receptor/0.477
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.477
3w5p4OAVitamin D3 receptor/0.477
4ixgIXGDihydrofolate reductase1.5.1.30.477
4rujVDXVitamin D3 receptor A/0.477
4rupH97Vitamin D3 receptor A/0.477
1diuBDMDihydrofolate reductase1.5.1.30.476
1uymPU3Heat shock protein HSP 90-beta/0.476
1wxyFRKAdenosine deaminase3.5.4.40.476
2fpcSCGStrictosidine synthase4.3.3.20.476
2gvjDGBNicotinamide phosphoribosyltransferase2.4.2.120.476
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.476
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.476
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.476
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.476
4b2wBZ0Glucose-1-phosphate thymidylyltransferase/0.476
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.476
4irnFADAnaB/0.476
1axwMTXThymidylate synthase/0.475
1cd2FOLDihydrofolate reductase1.5.1.30.475
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.475
1uofPNNDeacetoxycephalosporin C synthase1.14.20.10.475
1uomPTIEstrogen receptor/0.475
2uxpCLMHTH-type transcriptional regulator TtgR/0.475
3sf6FDAGlutaryl-CoA dehydrogenase/0.475
3tm5SFGUncharacterized protein/0.475
4b1rITCTetracycline repressor protein class D/0.475
4mlp2CXCryptochrome-2/0.475
1cjkFOKAdenylate cyclase type 2/0.474
1cjkFOKAdenylate cyclase type 5/0.474
1rx6DDFDihydrofolate reductase1.5.1.30.474
2pnuENMAndrogen receptor/0.474
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.474
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
3sa27DRDihydrofolate reductase/0.474
2z3uCRRCytochrome P450/0.473
2zb8IMNProstaglandin reductase 21.3.1.480.473
3gwfFADCyclohexanone monooxygenase/0.473
3hz5Z64Heat shock protein HSP 90-alpha/0.473
3qlzQLZUncharacterized protein/0.473
3v49PK0Androgen receptor/0.473
4fhi0S4Vitamin D3 receptor A/0.473
4fj2QSO17beta-hydroxysteroid dehydrogenase/0.473
1ie9VDXVitamin D3 receptor/0.472
1iyzNDPProbable quinone oxidoreductase/0.472
1upw444Oxysterols receptor LXR-beta/0.472
2fwyH64Heat shock protein HSP 90-alpha/0.472
2hcdBIVVitamin D3 receptor A/0.472
2ij7TPFMycocyclosin synthase1.14.21.90.472
2jf9OHTEstrogen receptor/0.472
3c3xNAPEugenol synthase 11.1.1.3180.472
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.472
3stv3HOMethylketone synthase I/0.472
3zkyWT4Isopenicillin N synthase1.21.3.10.472
4q0a4OAVitamin D3 receptor A/0.472
4wa9AXITyrosine-protein kinase ABL12.7.10.20.472
1uy8PU5Heat shock protein HSP 90-alpha/0.471
2z97CAMCamphor 5-monooxygenase1.14.15.10.471
2zbaZBATrichothecene 3-O-acetyltransferase/0.471
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
3vrtYS2Vitamin D3 receptor/0.471
3vtdTKDVitamin D3 receptor/0.471
4a81DXCMajor pollen allergen Bet v 1-A/0.471
4h9753SDihydrofolate reductase1.5.1.30.471
4jlj1NMDeoxycytidine kinase2.7.1.740.471
4nh82LCHeat shock protein HSP 90-alpha/0.471
1adfTADAlcohol dehydrogenase E chain1.1.1.10.470
1pq6965Oxysterols receptor LXR-beta/0.470
1uyuCAMCamphor 5-monooxygenase1.14.15.10.470
2aclREARetinoic acid receptor RXR-alpha/0.470
2o4rVD5Vitamin D3 receptor/0.470
3eej53RUncharacterized protein/0.470
3eem53VUncharacterized protein/0.470
3h3t16HCollagen type IV alpha-3-binding protein/0.470
3qj5022Alcohol dehydrogenase class-31.1.1.10.470
3vrvYSDVitamin D3 receptor/0.470
3w0c6DSVitamin D3 receptor/0.470
5d3fFSC14-3-3 protein zeta/delta/0.470
1disBDMDihydrofolate reductase1.5.1.30.469
1mczRMNBenzoylformate decarboxylase4.1.1.70.469
1o76CAMCamphor 5-monooxygenase1.14.15.10.469
1qxlFR8Adenosine deaminase3.5.4.40.469
1rx8FOLDihydrofolate reductase1.5.1.30.469
1sq5ADPPantothenate kinase2.7.1.330.469
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3oom507Activin receptor type-12.7.11.300.469
3v94WYQPhosphodiesterase/0.469
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.469
4ele31IDihydrofolate reductase/0.469
4lwwLWWNicotinamide phosphoribosyltransferase2.4.2.120.469
4m2xTMQDihydrofolate reductase1.5.1.30.469
2m56CAMCamphor 5-monooxygenase1.14.15.10.468
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
3d75NBBPheromone-binding protein ASP1/0.468
3eek53SUncharacterized protein/0.468
3l0lHC3Nuclear receptor ROR-gamma/0.468
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
3wiyLC6Induced myeloid leukemia cell differentiation protein Mcl-1/0.468
4eh9IRGMitogen-activated protein kinase 14/0.468
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.468
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.468
1bwlFMNNADPH dehydrogenase 11.6.99.10.467
1drbMTXDihydrofolate reductase1.5.1.30.467
1dz6CAMCamphor 5-monooxygenase1.14.15.10.467
1o6qR17Squalene--hopene cyclase4.2.1.1290.467
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.467
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.467
1uydPU8Heat shock protein HSP 90-alpha/0.467
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.467
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.467
2ewpTXFEstrogen-related receptor gamma/0.467
2harOCCVitamin D3 receptor/0.467
2uxoTACHTH-type transcriptional regulator TtgR/0.467
3csdEMOPutative ketoacyl reductase1.3.10.467
3vrwYS5Vitamin D3 receptor/0.467
2vn0TDZCytochrome P450 2C8/0.466
3d0bSNXHeat shock protein HSP 90-alpha/0.466
3inwJZBHeat shock protein HSP 90-alpha/0.466
3jw5TOPDihydrofolate reductase/0.466
3jzfJZKBiotin carboxylase6.3.4.140.466
3och2MXDihydrofolate reductase1.5.1.30.466
3otwCOAPhosphopantetheine adenylyltransferase/0.466
4cd2FOLDihydrofolate reductase1.5.1.30.466
4eh4IRGMitogen-activated protein kinase 14/0.466
4qa0SHHHistone deacetylase 83.5.1.980.466
5ab7MLCNonspecific lipid-transfer protein, putative/0.466
1ezfIN0Squalene synthase2.5.1.210.465
1ndzFR5Adenosine deaminase3.5.4.40.465
1thnADPAnti-sigma F factor/0.465
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
2z7gEH9Adenosine deaminase3.5.4.40.465
2zl9VDAVitamin D3 receptor/0.465
3fzwEQUSteroid Delta-isomerase5.3.3.10.465
3m7rVDXVitamin D3 receptor/0.465
3p9tTCLRepressor/0.465
3q9bB3NAcetylpolyamine amidohydrolase/0.465
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.465
3u8dU8DPhospholipase A2, membrane associated/0.465
3w5tLHPVitamin D3 receptor/0.465
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
4dbw511Aldo-keto reductase family 1 member C3/0.465
4efuEFUHeat shock protein HSP 90-alpha/0.465
4egnTWOCytochrome P450/0.465
4g210VPVitamin D3 receptor A/0.465
4i2q1BTGag-Pol polyprotein2.7.7.490.465
4ltsLTSNicotinamide phosphoribosyltransferase2.4.2.120.465
4o71CPBBromodomain-containing protein 4/0.465
4psbGA3Cytokinin-specific binding protein/0.465
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.465
5cccDDFDihydrofolate reductase1.5.1.30.465
1iwiCAMCamphor 5-monooxygenase1.14.15.10.464
1m7aMQUDihydrofolate reductase1.5.1.30.464
1s3yTQTDihydrofolate reductase1.5.1.30.464
1uy7PU4Heat shock protein HSP 90-alpha/0.464
2vbpVB1Isopenicillin N synthase1.21.3.10.464
3datMTXDihydrofolate reductase/0.464
3vt9YI4Vitamin D3 receptor/0.464
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.464
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.464
4hw219HInduced myeloid leukemia cell differentiation protein Mcl-1/0.464
4itfTFYVitamin D3 receptor/0.464
4jx1CAHCamphor 5-monooxygenase1.14.15.10.464
1db1VDXVitamin D3 receptor/0.463
1e26GPBDihydrofolate reductase1.5.1.30.463
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
1rdtL79Retinoic acid receptor RXR-alpha/0.463
1s0zEB1Vitamin D3 receptor/0.463
1yrdCAMCamphor 5-monooxygenase1.14.15.10.463
2a1nCAMCamphor 5-monooxygenase1.14.15.10.463
2po7CHDFerrochelatase, mitochondrial4.99.1.10.463
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.463
3h18PMSEsterase/lipase/0.463
3w5rLOAVitamin D3 receptor/0.463
4fogC2FThymidylate synthase ThyA/0.463
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.463
4kfo1QSNicotinamide phosphoribosyltransferase2.4.2.120.463
4ryvZEAProtein LlR18A/0.463
1rkhVD2Vitamin D3 receptor/0.462
1tvrTB9Gag-Pol polyprotein2.7.7.490.462
1uyePU9Heat shock protein HSP 90-alpha/0.462
1x8vESLLanosterol 14-alpha demethylase1.14.13.700.462
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
3lakKR1Gag-Pol polyprotein2.7.7.490.462
3mqe416Prostaglandin G/H synthase 21.14.99.10.462
3nmpPYVAbscisic acid receptor PYL2/0.462
3qiyQI1Botulinum neurotoxin type A3.4.24.690.462
3vruYS3Vitamin D3 receptor/0.462
3vtbTKAVitamin D3 receptor/0.462
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.462
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
4l4bCAMCamphor 5-monooxygenase1.14.15.10.462
1aoeGW3Dihydrofolate reductase1.5.1.30.461
1dnaCB3Thymidylate synthase/0.461
1dz8CAMCamphor 5-monooxygenase1.14.15.10.461
1s9qOHTEstrogen-related receptor gamma/0.461
1umlFR4Adenosine deaminase3.5.4.40.461
2hb7O1CVitamin D3 receptor/0.461
2hc4VDXVitamin D3 receptor A/0.461
2qimZEAClass 10 plant pathogenesis-related protein/0.461
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.461
4bfpSWYTankyrase-22.4.2.300.461
4g3rCAMCamphor 5-monooxygenase1.14.15.10.461
4nb6444Nuclear receptor ROR-gamma/0.461
4o701QKBromodomain-containing protein 4/0.461
4phlPILPhosphodiesterase/0.461
1aiqCB3Thymidylate synthase/0.460
1iiuRTLRetinol-binding protein 4/0.460
1v7aFRCAdenosine deaminase3.5.4.40.460
2cd2FOLDihydrofolate reductase1.5.1.30.460
2iko7IGRenin3.4.23.150.460
2yiuSMACytochrome b/0.460
3bqdDAYGlucocorticoid receptor/0.460
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3g5hYTTMycocyclosin synthase1.14.21.90.460
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.460
3qm4PN0Cytochrome P450 2D6/0.460
3roy22ZCyclin-dependent kinase 22.7.11.220.460
3tk3CPZCytochrome P450 2B41.14.14.10.460
4dsbA8SAbscisic acid receptor PYL3/0.460
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.460
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.460
4jlk1NODeoxycytidine kinase2.7.1.740.460
4jnm1LJNicotinamide phosphoribosyltransferase2.4.2.120.460
4r20AERCytochrome P450 family 17 polypeptide 2/0.460
5cvhADPCasein kinase II subunit alpha2.7.11.10.460
1nooCAHCamphor 5-monooxygenase1.14.15.10.459
1s19MC9Vitamin D3 receptor/0.459
1t88CAMCamphor 5-monooxygenase1.14.15.10.459
1yinCM3Estrogen receptor/0.459
2dvlFADAcyl-CoA dehydrogenase/0.459
2ftoCB3Thymidylate synthase/0.459
2hl1A3SThreonine--tRNA ligase6.1.1.30.459
2iyaZIOOleandomycin glycosyltransferase/0.459
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.459
2q9fC3SCholesterol 24-hydroxylase/0.459
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.459
2ykjYKJHeat shock protein HSP 90-alpha/0.459
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.459
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.459
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
3ibdCPZCytochrome P450 2B61.14.130.459
3junAKDPhenazine biosynthesis protein A/B/0.459
3l6jZ90Alr2278 protein/0.459
3stxBKAMethylketone synthase I/0.459
3td8D2RDihydrofolate reductase1.5.1.30.459
3zr7OR8Progesterone receptor/0.459
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.459
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.459
4elb34RDihydrofolate reductase/0.459
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4jx1CAMCamphor 5-monooxygenase1.14.15.10.459
4l49CAMCamphor 5-monooxygenase1.14.15.10.459
4l4dCAMCamphor 5-monooxygenase1.14.15.10.459
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.459
4xe606UDihydrofolate reductase1.5.1.30.459
5cp4CAMCamphor 5-monooxygenase1.14.15.10.459
1ao8MTXDihydrofolate reductase1.5.1.30.458
1ay0TPPTransketolase 12.2.1.10.458
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
1cjuFOKAdenylate cyclase type 2/0.458
1cjuFOKAdenylate cyclase type 5/0.458
1dz4CAMCamphor 5-monooxygenase1.14.15.10.458
1gwqZTWEstrogen receptor/0.458
1oc1ASVIsopenicillin N synthase1.21.3.10.458
1sepBIOSepiapterin reductase1.1.1.1530.458
1txiTX5Vitamin D3 receptor/0.458
1v79FR7Adenosine deaminase3.5.4.40.458
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.458
3adaNADSubunit alpha of sarocosine oxidase/0.458
3hl7I46Mitogen-activated protein kinase 14/0.458
3ix4TX1Transcriptional activator protein LasR/0.458
3mdmFJZCholesterol 24-hydroxylase/0.458
3nj0PYVAbscisic acid receptor PYL2/0.458
3pqbVGPPutative oxidoreductase/0.458
3w0gW07Vitamin D3 receptor/0.458
3wrmCAMCamphor 5-monooxygenase1.14.15.10.458
4az3S35Lysosomal protective protein3.4.16.50.458
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.458
5aluHD2Bifunctional epoxide hydrolase 23.1.3.760.458
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.457
1rt2TNKGag-Pol polyprotein2.7.7.490.457
1suoCPZCytochrome P450 2B41.14.14.10.457
1zprCB3Thymidylate synthase/0.457
2bu9HFVIsopenicillin N synthase1.21.3.10.457
2i4qUA4Renin3.4.23.150.457
2j9lATPH(+)/Cl(-) exchange transporter 5/0.457
2pioDHTAndrogen receptor/0.457
2piuDHTAndrogen receptor/0.457
2w98P1ZProstaglandin reductase 21.3.1.480.457
2zzaFOLDihydrofolate reductase/0.457
3b9lAZZSerum albumin/0.457
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.457
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3h3qH13Collagen type IV alpha-3-binding protein/0.457
3l63CAMCamphor 5-monooxygenase1.14.15.10.457
3srsM23Dihydrofolate reductase1.5.1.30.457
4bgg844Activin receptor type-12.7.11.300.457
4bquCLRJapanin/0.457
4g1z0VPVitamin D3 receptor A/0.457
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.457
4hy6FJ1Heat shock protein HSP 90-alpha/0.457
4i8vBHFCytochrome P450 1A11.14.14.10.457
4iyg1HUStrictosidine synthase4.3.3.20.457
4l4cCAMCamphor 5-monooxygenase1.14.15.10.457
4mv1ADPBiotin carboxylase6.3.4.140.457
4nc3ERM5-hydroxytryptamine receptor 2B/0.457
4uyg73BBromodomain-containing protein 2/0.457
4x5gFOLDihydrofolate reductase1.5.1.30.457
5prcATZReaction center protein L chain/0.457
1og5SWFCytochrome P450 2C9/0.456
1pp9SMACytochrome b/0.456
1uy6PU3Heat shock protein HSP 90-alpha/0.456
1uyfPU1Heat shock protein HSP 90-alpha/0.456
1ysx4EBSerum albumin/0.456
2piwDHTAndrogen receptor/0.456
2pogWSTEstrogen receptor/0.456
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.456
2ykcYKCHeat shock protein HSP 90-alpha/0.456
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
2zawCAMCamphor 5-monooxygenase1.14.15.10.456
3a1l2CCCytochrome P450/0.456
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.456
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.456
3dauMTXDihydrofolate reductase1.5.1.30.456
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
3pe2E1BCasein kinase II subunit alpha2.7.11.10.456
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.456
3s7a684Dihydrofolate reductase1.5.1.30.456
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.456
4dymIYZActivin receptor type-12.7.11.300.456
4ek1CAMCamphor 5-monooxygenase1.14.15.10.456
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.456
4ib4ERM5-hydroxytryptamine receptor 2B/0.456
4j6dTESCytochrome P450 monooxygenase/0.456
1gebCAMCamphor 5-monooxygenase1.14.15.10.455
1ndeMONEstrogen receptor beta/0.455
1rx3MTXDihydrofolate reductase1.5.1.30.455
1rx5DDFDihydrofolate reductase1.5.1.30.455
1uzwCDHIsopenicillin N synthase1.21.3.10.455
1zeoC01Peroxisome proliferator-activated receptor gamma/0.455
1zrzBI1Protein kinase C iota type2.7.11.130.455
2bbqPFGThymidylate synthase/0.455
2jb4A14Isopenicillin N synthase1.21.3.10.455
2tscCB3Thymidylate synthase/0.455
2zlcVDXVitamin D3 receptor/0.455
3fwgCAMCamphor 5-monooxygenase1.14.15.10.455
3p67FMNPentaerythritol tetranitrate reductase/0.455
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.455
3up3XCAaceDAF-12/0.455
3vg9ZMAAdenosine receptor A2a/0.455
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.455
4b5bBBEGlucose-1-phosphate thymidylyltransferase/0.455
4ejh0QACytochrome P450 2A131.14.14.10.455
4ez8DHFThymidylate synthase2.1.1.450.455
4iaq2GM5-hydroxytryptamine receptor 1B/0.455
4rrdA3TProbable threonine--tRNA ligase 26.1.1.30.455
4uymVOR14-alpha sterol demethylase Cyp51B/0.455
6cp4CAMCamphor 5-monooxygenase1.14.15.10.455
1dyrTOPDihydrofolate reductase1.5.1.30.454
1u0hFOKAdenylate cyclase type 2/0.454
1u0hFOKAdenylate cyclase type 5/0.454
1y4lSVRBasic phospholipase A2 homolog 2/0.454
1yrcCAMCamphor 5-monooxygenase1.14.15.10.454
2bgjFADNADPH:ferredoxin reductase/0.454
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2lbaCHOFatty acid binding protein 6/0.454
2q70DC8Estrogen receptor/0.454
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
3d90NOGProgesterone receptor/0.454
3elm24FCollagenase 33.4.240.454
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
3q44D50M1 family aminopeptidase3.4.110.454
3r6xX84Cyclin-dependent kinase 22.7.11.220.454
4bbhNHWGlycylpeptide N-tetradecanoyltransferase/0.454
4gevCB3Thymidylate synthase/0.454
4h9814QUncharacterized protein/0.454
4j6cSTRCytochrome P450 monooxygenase/0.454
4kfn1QRNicotinamide phosphoribosyltransferase2.4.2.120.454
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.454
4nx7FOLDihydrofolate reductase1.5.1.30.454
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.454
1e7aPFLSerum albumin/0.453
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.453
1tkaN3TTransketolase 12.2.1.10.453
2aaxPDNMineralocorticoid receptor/0.453
2jfaRALEstrogen receptor/0.453
2q7kTESAndrogen receptor/0.453
2qblCAMCamphor 5-monooxygenase1.14.15.10.453
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.453
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.453
3c15FOKAdenylate cyclase type 2/0.453
3c15FOKAdenylate cyclase type 5/0.453
3lxeTORCarbonic anhydrase 14.2.1.10.453
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.453
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3qlwN22Dihydrofolate reductase1.5.1.30.453
3stw2TDMethylketone synthase I/0.453
4a2jAS0Progesterone receptor/0.453
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.453
4hu1V13Carbonic anhydrase 134.2.1.10.453
4m4922YL-lactate dehydrogenase A chain1.1.1.270.453
4odoFK5Peptidyl-prolyl cis-trans isomerase/0.453
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.453
4rtsSAMDNA adenine methylase2.1.1.720.453
4zthGG5Mitogen-activated protein kinase 14/0.453
5a0112VO-glycosyltransferase/0.453
1bzfTMQDihydrofolate reductase1.5.1.30.452
1gs4ZK5Androgen receptor/0.452
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1nasASESepiapterin reductase1.1.1.1530.452
1r8qAFBCytohesin-2/0.452
1r8qAFBADP-ribosylation factor 1/0.452
1rx7FOLDihydrofolate reductase1.5.1.30.452
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
2b55D31Cyclin-dependent kinase 22.7.11.220.452
2feuCAMCamphor 5-monooxygenase1.14.15.10.452
2hl2SSAThreonine--tRNA ligase6.1.1.30.452
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3ha5SFGHydroxymycolate synthase MmaA42.1.10.452
3vt65YIVitamin D3 receptor/0.452
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.452
4g1y0VOVitamin D3 receptor A/0.452
4lsjLSJGlucocorticoid receptor/0.452
4mryCEIObelin/0.452
4oal245Cytokinin dehydrogenase 4/0.452
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.452
4xwtU5PRibonuclease J/0.452
5stdUNNScytalone dehydratase4.2.1.940.452
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.451
1cjvFOKAdenylate cyclase type 2/0.451
1cjvFOKAdenylate cyclase type 5/0.451
1eioGCHGastrotropin/0.451
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
1osvCHCBile acid receptor/0.451
1ppjSMACytochrome b/0.451
1t87CAMCamphor 5-monooxygenase1.14.15.10.451
1u1d181Uridine phosphorylase2.4.2.30.451
1zdwFLVPrenyltransferase/0.451
2f8pCEIObelin/0.451
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.451
2pirDHTAndrogen receptor/0.451
2qk8MTXDihydrofolate reductase/0.451
2xvhFADPutative flavin-containing monooxygenase/0.451
2xviFADPutative flavin-containing monooxygenase/0.451
2y60M8FIsopenicillin N synthase1.21.3.10.451
2z4jDHTAndrogen receptor/0.451
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.451
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.451
3ddpRC8Cyclin-dependent kinase 22.7.11.220.451
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3fhxPXLPyridoxal kinase2.7.1.350.451
3qdd94MHeat shock protein HSP 90-alpha/0.451
3srwQ27Dihydrofolate reductase1.5.1.30.451
3t3r9PLCytochrome P450 2A61.14.130.451
3tqbFOLDihydrofolate reductase/0.451
3w0hW12Vitamin D3 receptor/0.451
4a0sCO8Octenoyl-CoA reductase/carboxylase/0.451
4enhFVXCholesterol 24-hydroxylase/0.451
4fgh0U6Dihydrofolate reductase1.5.1.30.451
4i6gFADCryptochrome-2/0.451
4jr51LSNicotinamide phosphoribosyltransferase2.4.2.120.451
4lva20MNicotinamide phosphoribosyltransferase2.4.2.120.451
4tuvCPZCytochrome P450 1191.140.451
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.451
3emlZMAAdenosine receptor A2a/0.451
1fm99CRRetinoic acid receptor RXR-alpha/0.450
1jutLYDThymidylate synthase/0.450
1kquBR4Phospholipase A2, membrane associated/0.450
1ly4COQDihydrofolate reductase1.5.1.30.450
1ndyFR3Adenosine deaminase3.5.4.40.450
1rd4L08Integrin alpha-L/0.450
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.450
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
2d29FADAcyl-CoA dehydrogenase/0.450
2e1zB4PPropionate kinase/0.450
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.450
2nn7M29Carbonic anhydrase 14.2.1.10.450
2p1u4TNRetinoic acid receptor RXR-alpha/0.450
2pauD5M5'-deoxynucleotidase YfbR/0.450
2pvlP55Casein kinase II subunit alpha2.7.11.10.450
2w6nOA2Biotin carboxylase6.3.4.140.450
2w6oOA3Biotin carboxylase6.3.4.140.450
2zjwREFCasein kinase II subunit alpha2.7.11.10.450
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
3fwiCAMCamphor 5-monooxygenase1.14.15.10.450
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
3new3NEMitogen-activated protein kinase 14/0.450
3oafOAGDihydrofolate reductase1.5.1.30.450
3oapREARetinoic acid receptor RXR-alpha/0.450
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.450
3own3OWRenin3.4.23.150.450
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.450
3qtrX36Cyclin-dependent kinase 22.7.11.220.450
3w0jT08Vitamin D3 receptor/0.450
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.450
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.450
4b4gKKTGlucose-1-phosphate thymidylyltransferase/0.450
4bb3KKAIsopenicillin N synthase1.21.3.10.450
4bchT7ZCyclin-dependent kinase 92.7.11.220.450
4boeCLRJapanin/0.450
4eh6IRGMitogen-activated protein kinase 14/0.450
4j6i1JVPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4kkyCAMCamphor 5-monooxygenase1.14.15.10.450
4m6q20TNicotinamide phosphoribosyltransferase2.4.2.120.450
4udaDEXMineralocorticoid receptor/0.450
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.450
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.450
1i9hBNIStreptavidin/0.449
1kzjCB3Thymidylate synthase/0.449
1opbRETRetinol-binding protein 2/0.449
1re9DSOCamphor 5-monooxygenase1.14.15.10.449
1t86CAMCamphor 5-monooxygenase1.14.15.10.449
1zg32HIIsoflavone 4'-O-methyltransferase/0.449
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2qg2A91Heat shock protein HSP 90-alpha/0.449
3acw651Dehydrosqualene synthase/0.449
3aqaBYHBromodomain-containing protein 2/0.449
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.449
3cppCAMCamphor 5-monooxygenase1.14.15.10.449
3d76NBBPheromone-binding protein ASP1/0.449
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.449
3fl8RARDihydrofolate reductase/0.449
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
3ix8TX3Transcriptional activator protein LasR/0.449
3lkhLT6Genome polyprotein2.7.7.480.449
3m08RARDihydrofolate reductase1.5.1.30.449
3mtfA3FActivin receptor type-12.7.11.300.449
3tdaPN0Cytochrome P450 2D6/0.449
4aosNAPSteroid monooxygenase/0.449
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4ead0NPThymidine phosphorylase2.4.2.40.449
4jlt8PRCytochrome P450 2B41.14.14.10.449
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.449
4oicA8SBet v I allergen-like/0.449
5hyrESTEstrogen receptor/0.449
1bwsNDPGDP-L-fucose synthase/0.448
1cjtFOKAdenylate cyclase type 2/0.448
1cjtFOKAdenylate cyclase type 5/0.448
1crbRTLRetinol-binding protein 1/0.448
1dhjMTXDihydrofolate reductase1.5.1.30.448
1i59ADPChemotaxis protein CheA2.7.13.30.448
1mvsDTMDihydrofolate reductase1.5.1.30.448
1rk3VDXVitamin D3 receptor/0.448
1xp1AIHEstrogen receptor/0.448
2cppCAMCamphor 5-monooxygenase1.14.15.10.448
2wi4ZZ4Heat shock protein HSP 90-alpha/0.448
3dl9V2HVitamin D 25-hydroxylase/0.448
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3o0iP54Heat shock protein HSP 90-alpha/0.448
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3sai9DRDihydrofolate reductase/0.448
3uvvREARetinoic acid receptor RXR-alpha/0.448
3zoiM2WIsopenicillin N synthase1.21.3.10.448
4i22IREEpidermal growth factor receptor2.7.10.10.448
4jnc1LFBifunctional epoxide hydrolase 23.1.3.760.448
4ktl1CQCytochrome P450/0.448
4l4aCAMCamphor 5-monooxygenase1.14.15.10.448
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.448
4r21STRCytochrome P450 family 17 polypeptide 2/0.448
4u7wNDPMxaA/0.448
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
5k2dZMAAdenosine receptor A2a/0.448
1dyjDDFDihydrofolate reductase1.5.1.30.447
1e7qNAPGDP-L-fucose synthase/0.447
1i59ANPChemotaxis protein CheA2.7.13.30.447
1ie8KH1Vitamin D3 receptor/0.447
1kt6RTLRetinol-binding protein 4/0.447
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
1n83CLRNuclear receptor ROR-alpha/0.447
1obnASVIsopenicillin N synthase1.21.3.10.447
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1rfuADPPyridoxal kinase2.7.1.350.447
1sreHABStreptavidin/0.447
1uhhCZPAequorin-2/0.447
1xp9AIJEstrogen receptor/0.447
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.447
1z5cADPType 2 DNA topoisomerase 6 subunit B/0.447
2b1z17MEstrogen receptor/0.447
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.447
2i1vADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.447
2obxINI6,7-dimethyl-8-ribityllumazine synthase 22.5.1.780.447
2pitDHTAndrogen receptor/0.447
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.447
2w9gTOPDihydrofolate reductase1.5.1.30.447
3bgxMEFThymidylate synthase/0.447
3drcMTXDihydrofolate reductase1.5.1.30.447
3ft8MOJHeat shock protein HSP 90-alpha/0.447
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
4a84DXCMajor pollen allergen Bet v 1-A/0.447
4awp99AHeat shock protein HSP 90-alpha/0.447
4b4bGJBGlucose-1-phosphate thymidylyltransferase/0.447
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.447
4ipw1G7Mycocyclosin synthase1.14.21.90.447
4iq71G9Mycocyclosin synthase1.14.21.90.447
4lb2DM5Serum albumin/0.447
4rrrA3TThreonine--tRNA ligase6.1.1.30.447
4wqmFADToluene-4-monooxygenase electron transfer component1.18.1.30.447
5ikqJMSProstaglandin G/H synthase 21.14.99.10.447
1bifAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.446
1dg7WRBDihydrofolate reductase1.5.1.30.446
1kceCB3Thymidylate synthase/0.446
1qzfFOLBifunctional dihydrofolate reductase-thymidylate synthase/0.446
1wl4COAAcetyl-CoA acetyltransferase, cytosolic2.3.1.90.446
1xj7DHTAndrogen receptor/0.446
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.446
2gvcFADThiol-specific monooxygenase1.14.130.446
2izfBTNStreptavidin/0.446
2o4jVD4Vitamin D3 receptor/0.446
2ociTYCValacyclovir hydrolase3.10.446
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.446
2xy93ESAngiotensin-converting enzyme3.2.10.446
3d78NBBPheromone-binding protein ASP1/0.446
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3i0rRT3Gag-Pol polyprotein2.7.7.490.446
3jynNDPQuinone oxidoreductase/0.446
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3m31FADEndoplasmic oxidoreductin-11.8.40.446
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.446
3p8z36AGenome polyprotein2.1.1.560.446
3qlrQLRDihydrofolate reductase1.5.1.30.446
3rpnGTXGlutathione S-transferase kappa 12.5.1.180.446
3s79ASDAromatase1.14.14.140.446
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.446
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.446
4apuA2KProgesterone receptor/0.446
4elg52JDihydrofolate reductase/0.446
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4g2gTDHMycocyclosin synthase1.14.21.90.446
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4jlm1NNDeoxycytidine kinase2.7.1.740.446
4lvg20ONicotinamide phosphoribosyltransferase2.4.2.120.446
4oaeCLMUncharacterized protein/0.446
4rrfA3SThreonine--tRNA ligase6.1.1.30.446
4rtmSAMDNA adenine methylase2.1.1.720.446
4zm6ACON-acetyl-beta-D glucosaminidase/0.446
4z9g1Q5Corticotropin-releasing factor receptor 1/0.446
1ddtAPUDiphtheria toxin/0.445
1dhiMTXDihydrofolate reductase1.5.1.30.445
1fm4DXCMajor pollen allergen Bet v 1-L/0.445
1fxoTMPGlucose-1-phosphate thymidylyltransferase/0.445
1jomFFODihydrofolate reductase1.5.1.30.445
1tdrMTXDihydrofolate reductase1.5.1.30.445
1xddAAYIntegrin alpha-L/0.445
2bxqIMNSerum albumin/0.445
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
2imfTOM2-hydroxychromene-2-carboxylate isomerase5.99.1.40.445
2r64740Cyclin-dependent kinase 22.7.11.220.445
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.445
2xvq9DSSerum albumin/0.445
2xweAMFGlucosylceramidase3.2.1.450.445
2yisI46Mitogen-activated protein kinase 14/0.445
3c1oNAPEugenol synthase/0.445
3dd125DGlycogen phosphorylase, liver form2.4.1.10.445
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3freTOPDihydrofolate reductase1.5.1.30.445
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3g6zA7TRenin3.4.23.150.445
3gcoVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.445
3gncQQQGlutaryl-CoA dehydrogenase/0.445
3inxJZCHeat shock protein HSP 90-alpha/0.445
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3jziJZLBiotin carboxylase6.3.4.140.445
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.445
3nup3NUCyclin-dependent kinase 62.7.11.220.445
3stdMQ0Scytalone dehydratase4.2.1.940.445
3wrhCAMCamphor 5-monooxygenase1.14.15.10.445
4awo99BHeat shock protein HSP 90-alpha/0.445
4b42942Glucose-1-phosphate thymidylyltransferase/0.445
4e0u0MVCyclic dipeptide N-prenyltransferase/0.445
4e2bFMNDehydrogenase/0.445
4grb0XGCasein kinase II subunit alpha2.7.11.10.445
4hxs1A3Bromodomain-containing protein 4/0.445
4qa2SHHHistone deacetylase 83.5.1.980.445
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.445
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.445
1bv7XV6Gag-Pol polyprotein3.4.23.160.444
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.444
1pq944BOxysterols receptor LXR-beta/0.444
1s9pDESEstrogen-related receptor gamma/0.444
1uykPUXHeat shock protein HSP 90-alpha/0.444
2agvTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.444
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.444
2c3u2TPPyruvate synthase/0.444
2h55DZ8Heat shock protein HSP 90-alpha/0.444
2oaxSNLMineralocorticoid receptor/0.444
2rqfJH3Hemolymph juvenile hormone binding protein/0.444
2vcmM11Isopenicillin N synthase1.21.3.10.444
2vqbFADPutative flavin-containing monooxygenase/0.444
2xlrFADPutative flavin-containing monooxygenase/0.444
2z2w770Wee1-like protein kinase2.7.10.20.444
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
3fc6REARetinoic acid receptor RXR-alpha/0.444
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.444
3ghvGHCDihydrofolate reductase1.5.1.30.444
3h3sH15Collagen type IV alpha-3-binding protein/0.444
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
3q33ACOHistone acetyltransferase RTT1092.3.1.480.444
3q9xEMOCasein kinase II subunit alpha2.7.11.10.444
3sa16DRDihydrofolate reductase/0.444
3srqQ19Dihydrofolate reductase1.5.1.30.444
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
3zhtTD9Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.444
4asjN6AGlucose-1-phosphate thymidylyltransferase/0.444
4bqrIBHEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4elf35IDihydrofolate reductase/0.444
4g95OAGDihydrofolate reductase1.5.1.30.444
4iae1DXAlr2278 protein/0.444
4ict1EDMycocyclosin synthase1.14.21.90.444
4ivy1GTEstrogen receptor/0.444
4jvmXDIEstrogen sulfotransferase2.8.2.40.444
4kjjFOLDihydrofolate reductase1.5.1.30.444
4l4xNDPAmphI/0.444
4mr61K0Bromodomain-containing protein 2/0.444
4p6wMOFGlucocorticoid receptor/0.444
4pztSOPHistone acetyltransferase p300/0.444
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.444
4udcDEXGlucocorticoid receptor/0.444
4x5jFOLDihydrofolate reductase1.5.1.30.444
4y8wSTRSteroid 21-hydroxylase/0.444
4yekTHMThymidine phosphorylase/0.444
5ab6CAANonspecific lipid-transfer protein, putative/0.444
1blzACVIsopenicillin N synthase1.21.3.10.443
1dr3HBIDihydrofolate reductase1.5.1.30.443
1nceCB3Thymidylate synthase/0.443
1s36CEIObelin/0.443
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.443
1unlRRCCyclin-dependent-like kinase 52.7.11.10.443
1ykdCMPAdenylate cyclase/0.443
2bf7HBIPteridine reductase 11.5.1.330.443
2fai459Estrogen receptor/0.443
2fwzH71Heat shock protein HSP 90-alpha/0.443
2hbhXE4Vitamin D3 receptor A/0.443
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.443
2yk2YJXHeat shock protein HSP 90-alpha/0.443
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3eel53TUncharacterized protein/0.443
3hub469Mitogen-activated protein kinase 14/0.443
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.443
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.443
3jw3TOPDihydrofolate reductase/0.443
3kxoKXOHematopoietic prostaglandin D synthase/0.443
3nxuRITCytochrome P450 3A4/0.443
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.443
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.443
3vt8YI3Vitamin D3 receptor/0.443
3w0tHPULactoylglutathione lyase4.4.1.50.443
3wrjCAMCamphor 5-monooxygenase1.14.15.10.443
4asyN5YGlucose-1-phosphate thymidylyltransferase/0.443
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.443
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.443
4bfsZVSPantothenate kinase2.7.1.330.443
4dlcUMPDeoxyuridine triphosphatase, putative/0.443
4g67SAHUncharacterized ACR, COG1565 superfamily/0.443
4men25KBromodomain-containing protein 4/0.443
4qe6JN3Bile acid receptor/0.443
4rrxLURProstaglandin G/H synthase 21.14.99.10.443
5ifiPRXAcetyl-coenzyme A synthetase/0.443
5k2cZMAAdenosine receptor A2a/0.443
1h1pCMGCyclin-dependent kinase 22.7.11.220.442
1h35R01Squalene--hopene cyclase4.2.1.1290.442
1iwjCAMCamphor 5-monooxygenase1.14.15.10.442
1kt3RTLRetinol-binding protein 4/0.442
1rf7DHFDihydrofolate reductase1.5.1.30.442
1t7tDHTAndrogen receptor/0.442
2hvcLGDAndrogen receptor/0.442
2ihvTPPN(2)-(2-carboxyethyl)arginine synthase/0.442
2npnSAMPutative cobalamin synthesis related protein/0.442
2pklDHTAndrogen receptor/0.442
2qe4JJ3Estrogen receptor/0.442
2qgtEEDEstrogen receptor/0.442
2rhrEMOPutative ketoacyl reductase1.3.10.442
2v5aLZLBiotin carboxylase6.3.4.140.442
2xgoZKDUncharacterized protein/0.442
2yloTESAndrogen receptor/0.442
2ylpTESAndrogen receptor/0.442
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.442
2ze2T27Gag-Pol polyprotein2.7.7.490.442
3cv9VDXVitamin D3 dihydroxylase/0.442
3dxjNE6DNA-directed RNA polymerase subunit beta/0.442
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.442
3fywXCFDihydrofolate reductase1.5.1.30.442
3gwfNAPCyclohexanone monooxygenase/0.442
3jpuTY4Transcriptional activator protein LasR/0.442
3mnrSD1Heat shock protein HSP 90-alpha/0.442
3oqkS52Renin3.4.23.150.442
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3r0tFU9Casein kinase II subunit alpha2.7.11.10.442
4bmpFMNProtein NrdI/0.442
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.442
4dhyS41Glucokinase2.7.1.20.442
4g20484Vitamin D3 receptor A/0.442
4g47TZFMycocyclosin synthase1.14.21.90.442
4kf1HT5Aryldialkylphosphatase3.1.8.10.442
4ktf1TMCytochrome P450/0.442
4ktkKTKCytochrome P450/0.442
4m8hR4MRetinoic acid receptor RXR-alpha/0.442
4olfHFGProline--tRNA ligase6.1.1.150.442
4x5fFOLDihydrofolate reductase1.5.1.30.442
4z1fH71Heat shock protein 75 kDa, mitochondrial/0.442
5e8ySTUTGF-beta receptor type-22.7.11.300.442
5kghACOPredicted acetyltransferase/0.442
7dfrFOLDihydrofolate reductase1.5.1.30.442
1bk0ACVIsopenicillin N synthase1.21.3.10.441
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1gij2PUCyclin-dependent kinase 22.7.11.220.441
1k749CRRetinoic acid receptor RXR-alpha/0.441
1ly3COGDihydrofolate reductase1.5.1.30.441
1metDMPGag-Pol polyprotein3.4.23.160.441
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.441
1t5zDHTAndrogen receptor/0.441
1uyiPUZHeat shock protein HSP 90-alpha/0.441
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2hb8MVDVitamin D3 receptor/0.441
2ihuTP9N(2)-(2-carboxyethyl)arginine synthase/0.441
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.441
2pulACPMethylthioribose kinase2.7.1.1000.441
2q5qTPWIndole-3-pyruvate decarboxylase4.1.1.740.441
2qjpSMACytochrome b/0.441
2vkeTACTetracycline repressor protein class D/0.441
2vqoTFGHistone deacetylase 43.5.1.980.441
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.441
2yeiXQIHeat shock protein HSP 90-alpha/0.441
2ykbYKBHeat shock protein HSP 90-alpha/0.441
2yltFADPhenylacetone monooxygenase1.14.13.920.441
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
3biz61EWee1-like protein kinase2.7.10.20.441
3gfbNADL-threonine 3-dehydrogenase/0.441
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.441
3ielU5PRibonuclease TTHA02523.10.441
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3kytHC2Nuclear receptor ROR-gamma/0.441
3pe6ZYHMonoglyceride lipase/0.441
3qwiCUE17beta-hydroxysteroid dehydrogenase/0.441
3vt3VDXVitamin D3 receptor/0.441
3w0iO11Vitamin D3 receptor/0.441
3w78CBDFMN-dependent NADH-azoreductase/0.441
4bhw01KHistone acetyltransferase p300/0.441
4c68NHWGlycylpeptide N-tetradecanoyltransferase/0.441
4eiyZMAAdenosine receptor A2a/0.441
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.441
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4h9tHL4Phosphotriesterase/0.441
4hnc0UTMandelate racemase/0.441
4ihl1F514-3-3 protein zeta/delta/0.441
4mzuTYDWxcM-like protein/0.441
4qa1B3NHistone deacetylase 83.5.1.980.441
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.441
5c8yACPTubulin tyrosine ligase/0.441
5kf9ACOPredicted acetyltransferase/0.441
1fbyREARetinoic acid receptor RXR-alpha/0.440
1gwrESTEstrogen receptor/0.440
1tduCB3Thymidylate synthase/0.440
1xowR18Androgen receptor/0.440
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
2fnaADPUncharacterized protein/0.440
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.440
2hamC33Vitamin D3 receptor/0.440
2i0ePDSProtein kinase C beta type2.7.11.130.440
2iviACWIsopenicillin N synthase1.21.3.10.440
2p15EZTEstrogen receptor/0.440
2q7iTESAndrogen receptor/0.440
2vzmNRBCytochrome P450 monooxygenase PikC/0.440
2w71L23Biotin carboxylase6.3.4.140.440
2zaxCAMCamphor 5-monooxygenase1.14.15.10.440
3bgrT27Gag-Pol polyprotein2.7.7.490.440
3bt9DEQHTH-type transcriptional regulator QacR/0.440
3falREARetinoic acid receptor RXR-alpha/0.440
3lu8IQXSerum albumin/0.440
3nga3NGCasein kinase II subunit alpha2.7.11.10.440
3r1qX75Cyclin-dependent kinase 22.7.11.220.440
3r7iX9ICyclin-dependent kinase 22.7.11.220.440
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.440
3ry2BTNStreptavidin/0.440
3ttiKBIMitogen-activated protein kinase 102.7.11.240.440
3v4aPK1Androgen receptor/0.440
3w0yDS4Vitamin D3 receptor/0.440
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.440
3zs5SB2Mitogen-activated protein kinase 14/0.440
4a51DQ8Kinesin-like protein KIF11/0.440
4a6eASEAcetylserotonin O-methyltransferase2.1.1.40.440
4b3aTACTetracycline repressor protein class D/0.440
4bfxZVXPantothenate kinase2.7.1.330.440
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.440
4dfrMTXDihydrofolate reductase1.5.1.30.440
4dijBLFE3 ubiquitin-protein ligase Mdm26.3.20.440
4dk70KSOxysterols receptor LXR-beta/0.440
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4eh7IRGMitogen-activated protein kinase 14/0.440
4fgg0U5Dihydrofolate reductase1.5.1.30.440
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4gub0Y4Casein kinase II subunit alpha2.7.11.10.440
4ixfIXFDihydrofolate reductase1.5.1.30.440
4jdaA9SAbscisic acid receptor PYL3/0.440
4o74R78Bromodomain-containing protein 4/0.440
4o761M3Bromodomain-containing protein 4/0.440
4rrgA3TThreonine--tRNA ligase6.1.1.30.440
4rtrSAMDNA adenine methylase2.1.1.720.440
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.440
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.440
5k2bZMAAdenosine receptor A2a/0.440
4djhJDCKappa-type opioid receptor/0.440