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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4j75TYMTryptophan--tRNA ligase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4j75TYMTryptophan--tRNA ligase/1.000
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.553
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.540
2qujTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.540
3jxeTYMTryptophan--tRNA ligase/0.518
3kt3TYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.514
1i6kTYMTryptophan--tRNA ligase6.1.1.20.477
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.472
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.471
1jil485Tyrosine--tRNA ligase/0.463
1vbmYSATyrosine--tRNA ligase6.1.1.10.459
1n2hPAJPantothenate synthetase6.3.2.10.457
3tr05GPGuanylate kinase/0.456
1x1aSAMC-20 methyltransferase/0.446
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.442
2gjlFMNNitronate monooxygenase1.13.12.160.440