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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ikeADPAdenylate kinase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4ikeADPAdenylate kinase/1.000
4jldADPAdenylate kinase/0.627
4jloADPAdenylate kinase/0.602
4jl5ADPAdenylate kinase/0.589
4mkhAP5Adenylate kinase/0.580
4jkyADPAdenylate kinase/0.571
4jl6ADPAdenylate kinase/0.551
4cf7ADPAdenylate kinase/0.525
4typAP5Adenylate kinase/0.523
3tlxADPAdenylate kinase 2/0.514
3dl0AP5Adenylate kinase/0.496
4qbfAP5Adenylate kinase/0.482
1zioAP5Adenylate kinase/0.473
1e4yAP5Adenylate kinase/0.464
2ql6ADPNicotinamide riboside kinase 1/0.458
2qajAP5Adenylate kinase/0.451
4qbiAP5Adenylate kinase/0.449
1e4vAP5Adenylate kinase/0.441