sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4iif | CTS | Beta-glucosidase 1 | 3.2.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4iif | CTS | Beta-glucosidase 1 | 3.2.1.21 | 1.000 | |
| 4d6q | PD2 | Lysine-specific demethylase 4D | 1.14.11 | 0.497 | |
| 1fkd | 818 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.458 | |
| 1p72 | THM | Thymidine kinase | / | 0.456 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.452 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.452 | |
| 1tww | HH2 | Dihydropteroate synthase | / | 0.451 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.449 | |
| 1qs2 | NAD | Vip2Ac | / | 0.448 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.447 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.447 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.446 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.446 | |
| 4a1o | AMZ | Bifunctional purine biosynthesis protein PurH | 2.1.2.3 | 0.445 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.444 | |
| 3px2 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.444 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.443 | |
| 2jj8 | AZZ | Deoxynucleoside kinase | / | 0.443 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.443 | |
| 4kq1 | U5P | Glycogen [starch] synthase | / | 0.442 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.440 |