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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ihl1F514-3-3 protein zeta/delta

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4ihl1F514-3-3 protein zeta/delta/1.000
2o98FSC14-3-3-like protein C/0.504
5d3fFSC14-3-3 protein zeta/delta/0.483
3e6yCW114-3-3-like protein C/0.461
3smkCW714-3-3 protein sigma/0.458
1jmgUMPThymidylate synthase/0.457
1bidUMPThymidylate synthase/0.445
1njaDCMThymidylate synthase/0.440
1tsvUMPThymidylate synthase/0.440