sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ie5 | MD6 | Alpha-ketoglutarate-dependent dioxygenase FTO |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4ie5 | MD6 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 1.000 | |
| 4ie0 | PD2 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.612 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.612 | |
| 1gx1 | CDP | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.463 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1i7l | ATP | Synapsin-2 | / | 0.447 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.445 | |
| 3uu1 | 14B | Anthranilate phosphoribosyltransferase | / | 0.445 | |
| 4eaj | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.444 | |
| 4do0 | DZA | Histone lysine demethylase PHF8 | 1.14.11.27 | 0.443 | |
| 3m3z | 3F5 | Heat shock cognate 71 kDa protein | / | 0.440 |