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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ie0PD2Alpha-ketoglutarate-dependent dioxygenase FTO

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4ie0PD2Alpha-ketoglutarate-dependent dioxygenase FTO/1.000
4ie5MD6Alpha-ketoglutarate-dependent dioxygenase FTO/0.537
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.513
1i7lATPSynapsin-2/0.462
3t4hMD5Alpha-ketoglutarate-dependent dioxygenase AlkB1.14.11.330.454
2a4nCOAAac(6')-Ii protein/0.448
4bjzFADProbable salicylate monooxygenase/0.446
2c3qGTXGlutathione S-transferase theta-12.5.1.180.443