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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4i121BCBeta-secretase 13.4.23.46

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4i121BCBeta-secretase 13.4.23.461.000
4i111CHBeta-secretase 13.4.23.460.656
2ohr8IPBeta-secretase 13.4.23.460.600
4i1c1BEBeta-secretase 13.4.23.460.595
4i0z1BBBeta-secretase 13.4.23.460.565
2va6H24Beta-secretase 13.4.23.460.551
4i0f1BFBeta-secretase 13.4.23.460.550
2ohp6IPBeta-secretase 13.4.23.460.549
4ha513WBeta-secretase 13.4.23.460.545
2ohq7IPBeta-secretase 13.4.23.460.538
3bugAEHBeta-secretase 13.4.23.460.528
5c1mCLRMu-type opioid receptor/0.527
2va7C27Beta-secretase 13.4.23.460.525
4drm0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.520
2xncFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.517
4j1c1HOBeta-secretase 13.4.23.460.516
3zmg6Z0Beta-secretase 13.4.23.460.515
4drp0MDPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.515
3exo5MSBeta-secretase 13.4.23.460.514
4j171HQBeta-secretase 13.4.23.460.514
3zc3FADFerredoxin--NADP reductase1.18.1.20.511
1lnmDTXBilin-binding protein/0.510
4djv0KMBeta-secretase 13.4.23.460.510
1f20FADNitric oxide synthase, brain1.14.13.390.507
4jtrIZPAldo-keto reductase family 1 member C2/0.507
2e8qSAHDiphthine synthase/0.506
3c3xNAPEugenol synthase 11.1.1.3180.506
4fs4H24Beta-secretase 13.4.23.460.505
4n3l2FNProthrombin3.4.21.50.503
1lkeDOGBilin-binding protein/0.502
2ek7SAHDiphthine synthase/0.502
2ohuIP7Beta-secretase 13.4.23.460.502
1h22E10Acetylcholinesterase3.1.1.70.501
1jwtBLIProthrombin3.4.21.50.501
4dro0MDPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.501
4j0y1H6Beta-secretase 13.4.23.460.501
1qgzFADFerredoxin--NADP reductase1.18.1.20.500
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.499
4b67NAPL-ornithine N(5)-monooxygenase/0.496
4bamMM9Prothrombin3.4.21.50.496
4j1e1HMBeta-secretase 13.4.23.460.496
4kbyC2EStimulator of interferon genes protein/0.496
2rehFADNitroalkane oxidase1.7.3.10.495
1qvuPRLHTH-type transcriptional regulator QacR/0.494
2zfr46UProthrombin3.4.21.50.494
2zhw12UProthrombin3.4.21.50.494
4b1c1B1Beta-secretase 13.4.23.460.494
1gawFADFerredoxin/0.493
1qh0FADFerredoxin--NADP reductase1.18.1.20.493
2pksG44Prothrombin3.4.21.50.493
3c1oNAPEugenol synthase/0.493
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.492
2d1oFA4Stromelysin-13.4.24.170.491
2pb4SAHDiphthine synthase/0.491
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.491
4jfi1KTPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.491
4lc71WPBeta-secretase 13.4.23.460.491
4lxm1YUBeta-secretase 13.4.23.460.491
2emrSAHDiphthine synthase/0.490
3c1kT15Prothrombin3.4.21.50.490
3fpkFADFerredoxin-NADP reductase/0.490
3zkyWT4Isopenicillin N synthase1.21.3.10.490
4layI63Peptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.490
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.489
1vzdCB3Thymidylate synthase/0.489
2anmCDOProthrombin3.4.21.50.489
3biu10UProthrombin3.4.21.50.489
3ho2N323-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.489
2e07SAHDiphthine synthase/0.488
2pncCLUPrimary amine oxidase, liver isozyme/0.488
3mjrAC2Deoxycytidine kinase2.7.1.740.488
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.488
1b2lNDCAlcohol dehydrogenase1.1.1.10.487
2vn1FK5Peptidylprolyl isomerase/0.487
2xi4AFTAcetylcholinesterase3.1.1.70.487
3af1GDPPantothenate kinase2.7.1.330.487
3e6eDCSAlanine racemase/0.487
4bfxZVXPantothenate kinase2.7.1.330.487
4ure1PSCyclohexanol dehydrogenase/0.487
2pb6SAHDiphthine synthase/0.486
2w6oOA3Biotin carboxylase6.3.4.140.486
1g63FMNEpidermin decarboxylase4.1.10.485
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.485
4a87NARMajor pollen allergen Bet v 1-A/0.485
1eveE20Acetylcholinesterase3.1.1.70.484
1ta6177Prothrombin3.4.21.50.484
1vceSAHDiphthine synthase/0.484
2emuSAHDiphthine synthase/0.484
2zg050UProthrombin3.4.21.50.484
2zhq27UProthrombin3.4.21.50.484
3qgf46FGenome polyprotein2.7.7.480.484
4mlp2CXCryptochrome-2/0.484
2ha6SCKAcetylcholinesterase3.1.1.70.483
2v3hI25Prothrombin3.4.21.50.483
3fsjD7KBenzoylformate decarboxylase4.1.1.70.483
3h3sH15Collagen type IV alpha-3-binding protein/0.483
3wqmB29Diterpene synthase3.1.7.80.483
4j1k1HGBeta-secretase 13.4.23.460.483
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.483
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.482
2qiqCYVReplicase polyprotein 1ab/0.482
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.482
4drkI63Peptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.482
1gjrFADFerredoxin--NADP reductase1.18.1.20.481
2dv4SAHDiphthine synthase/0.481
2en5SAHDiphthine synthase/0.481
3ivcFG4Pantothenate synthetase6.3.2.10.481
4djx0KQBeta-secretase 13.4.23.460.481
4hzt0ZABeta-secretase 13.4.23.460.481
5erm210Fusicoccadiene synthase4.2.3.430.481
1c4vIH2Prothrombin3.4.21.50.480
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.480
1x1bSAHC-20 methyltransferase/0.480
1zgcA2EAcetylcholinesterase3.1.1.70.480
2dv7SAHDiphthine synthase/0.480
2ehlSAHDiphthine synthase/0.480
2huxSAHDiphthine synthase/0.480
2zgb21UProthrombin3.4.21.50.480
3gdsVAL_TYR_TYR_PHESerine endoprotease DegS3.4.21.1070.480
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.480
1d3dBZTProthrombin3.4.21.50.479
1ikiREYD-alanyl-D-alanine carboxypeptidase3.4.16.40.479
2zhf49UProthrombin3.4.21.50.479
3gwfFADCyclohexanone monooxygenase/0.479
4jp91M5Beta-secretase 13.4.23.460.479
4y7cFMNNADPH--cytochrome P450 reductase/0.479
1fnbFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.478
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.478
1w76GNTAcetylcholinesterase3.1.1.70.478
1yqsBSAD-alanyl-D-alanine carboxypeptidase3.4.16.40.478
2dv3SAHDiphthine synthase/0.478
2ea4F79Methionine aminopeptidase 2/0.478
4a86H35Major pollen allergen Bet v 1-A/0.478
4b4w9L9Bifunctional protein FolD/0.478
1hb3SCVIsopenicillin N synthase1.21.3.10.477
2e1zB4PPropionate kinase/0.477
2p6lSAHDiphthine synthase/0.477
2zda32UProthrombin3.4.21.50.477
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.477
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.477
4b63NAPL-ornithine N(5)-monooxygenase/0.477
4j0p1H8Beta-secretase 13.4.23.460.477
4q0kGA3Phytohormone-binding protein/0.477
4rheFMNFlavin prenyltransferase UbiX/0.477
1e7qNAPGDP-L-fucose synthase/0.476
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.476
1zgbA1EAcetylcholinesterase3.1.1.70.476
3autNAIGlucose 1-dehydrogenase 41.1.1.470.476
3eksCY9Actin-5C/0.476
3mytEQUSteroid Delta-isomerase5.3.3.10.476
3s7dLEU_SER_LYS_LYS_MLZN-lysine methyltransferase SMYD2/0.476
4bftZVTPantothenate kinase2.7.1.330.476
4djy0KRBeta-secretase 13.4.23.460.476
4i101BSBeta-secretase 13.4.23.460.476
4jlm1NNDeoxycytidine kinase2.7.1.740.476
4relKMPGlycosyltransferase/0.476
1t4u81AProthrombin3.4.21.50.475
2w02ATPAcsD/0.475
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.475
4b7754MBeta-secretase 13.4.23.460.475
1fkbRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.474
1mueCDDProthrombin3.4.21.50.474
1mvtDTMDihydrofolate reductase1.5.1.30.474
1w87FADFerredoxin--NADP reductase1.18.1.20.474
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.474
1z71L17Prothrombin3.4.21.50.474
2x86ADPADP-L-glycero-D-manno-heptose-6-epimerase/0.474
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.474
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.474
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.474
4ax9N5NProthrombin3.4.21.50.474
4jpe1M7Beta-secretase 13.4.23.460.474
1bjkFADFerredoxin--NADP reductase1.18.1.20.473
1zgi382Prothrombin3.4.21.50.473
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.473
2bjuIH4Plasmepsin-23.4.23.390.473
2ipjFFAAldo-keto reductase family 1 member C2/0.473
2zgx29UProthrombin3.4.21.50.473
4dc0NDPPutative ketoacyl reductase1.3.10.473
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.473
1go2FADFerredoxin--NADP reductase1.18.1.20.472
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.472
3gcoVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.472
4afhL0BAchbp/0.472
4c43FADFerredoxin--NADP reductase1.18.1.20.472
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.472
4f0e0RUPoly [ADP-ribose] polymerase 152.4.2.300.472
4jtqNAPAldo-keto reductase family 1 member C2/0.472
4rn615UProthrombin3.4.21.50.472
1cnfFADNitrate reductase [NADH]1.7.1.10.471
1e62FADFerredoxin--NADP reductase1.18.1.20.471
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.471
1sb1165Prothrombin3.4.21.50.471
1w35FADFerredoxin--NADP reductase1.18.1.20.471
1x1cSAHC-20 methyltransferase/0.471
2eh5SAHDiphthine synthase/0.471
2fb35ADGTP 3',8-cyclase4.1.99.180.471
2pcmSAHDiphthine synthase/0.471
2zcvNDPQuinone oxidoreductase 21.6.5.20.471
2zdv37UProthrombin3.4.21.50.471
3udk095Beta-secretase 13.4.23.460.471
4b68NAPL-ornithine N(5)-monooxygenase/0.471
4b70WM9Beta-secretase 13.4.23.460.471
4bfvZVVPantothenate kinase2.7.1.330.471
4frjDWBBeta-secretase 13.4.23.460.471
4ise1FWGlucokinase2.7.1.20.471
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.470
1oc1ASVIsopenicillin N synthase1.21.3.10.470
2cbqTH2Neocarzinostatin/0.470
3f6891UProthrombin3.4.21.50.470
4bahMELProthrombin3.4.21.50.470
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.470
5a4vQUEGlutathione S-transferase F22.5.1.180.470
7kmeACE_0BN_CHG_PRRProthrombin3.4.21.50.470
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.469
1ppjANYCytochrome b/0.469
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.469
2wd8VGFPteridine reductase/0.469
2zf051UProthrombin3.4.21.50.469
2zff53UProthrombin3.4.21.50.469
3dhk23UProthrombin3.4.21.50.469
3dqrJI2Nitric oxide synthase, brain1.14.13.390.469
3fktSIIBeta-secretase 13.4.23.460.469
3lzxNAPFerredoxin--NADP reductase 21.18.1.20.469
3qftFADNADPH--cytochrome P450 reductase/0.469
3qwc98PProthrombin3.4.21.50.469
3vg10GTBeta-secretase 13.4.23.460.469
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.469
4gsuDWZL,D-transpeptidase 22.3.20.469
4isg1FYGlucokinase2.7.1.20.469
5irnADPNucleotide binding oligomerization domain containing 2/0.469
1u2rSO1Elongation factor 2/0.468
1vfsDCSAlanine racemase/0.468
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.468
2ek4SAHDiphthine synthase/0.468
2ohjFMNType A flavoprotein FprA10.468
2r6gATPMaltose/maltodextrin import ATP-binding protein MalK/0.468
2wzySQXSoluble acetylcholine receptor/0.468
3a6qFMNFMN-binding protein/0.468
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.468
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.468
3dux64UProthrombin3.4.21.50.468
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.468
3rtnRTNBeta-secretase 13.4.23.460.468
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.468
4eb7PLPCysteine desulfurase IscS 2/0.468
1dduDDUThymidylate synthase/0.467
1e64FADFerredoxin--NADP reductase1.18.1.20.467
1qgyFADFerredoxin--NADP reductase1.18.1.20.467
1ut6A8NAcetylcholinesterase3.1.1.70.467
1ypkCCRProthrombin3.4.21.50.467
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.467
2cekN8TAcetylcholinesterase3.1.1.70.467
2e8sSAHDiphthine synthase/0.467
2ejzSAHDiphthine synthase/0.467
2rc6FADFerredoxin--NADP reductase/0.467
3u8l09QAcetylcholine-binding protein/0.467
4bb3KKAIsopenicillin N synthase1.21.3.10.467
4wctFADFructosyl amine:oxygen oxidoreductase/0.467
1ae8AZLProthrombin3.4.21.50.466
1bil0IURenin3.4.23.150.466
1wngSAHDiphthine synthase/0.466
2bdyUNBProthrombin3.4.21.50.466
2eglSAHDiphthine synthase/0.466
2eniSAHDiphthine synthase/0.466
2owgSAHDiphthine synthase/0.466
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.466
3bnkFMNFlavoredoxin/0.466
3hy9098A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.466
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.466
4b7zQ4QAcetylcholinesterase3.1.1.70.466
4emrMGPRibosome inactivating protein/0.466
4jpc1M6Beta-secretase 13.4.23.460.466
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.466
1ef92CPMethylmalonyl-CoA decarboxylase4.1.1.410.465
1k22MELProthrombin3.4.21.50.465
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.465
1xs7MMIBeta-secretase 13.4.23.460.465
2eleSAHDiphthine synthase/0.465
2il2LIXRenin3.4.23.150.465
2nq8ZIDEnoyl-ACP reductase/0.465
2p5fSAHDiphthine synthase/0.465
2rqfJH3Hemolymph juvenile hormone binding protein/0.465
3bk2U5PRibonuclease J/0.465
4bqtC5ESoluble acetylcholine receptor/0.465
4drn0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.465
4ih61EPGenome polyprotein2.7.7.480.465
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.465
1njaDCMThymidylate synthase/0.464
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.464
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.464
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.464
1t4v14AProthrombin3.4.21.50.464
1tsvUMPThymidylate synthase/0.464
2dg4RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.464
2e16SAHDiphthine synthase/0.464
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.464
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.464
2ziq26UProthrombin3.4.21.50.464
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.464
3aosJH2Hemolymph juvenile hormone binding protein/0.464
3g11P9C3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.464
3k1wBFXRenin3.4.23.150.464
3ojxFMNNADPH--cytochrome P450 reductase/0.464
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.464
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.464
4c717RD3-oxoacyl-ACP synthase/0.464
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.464
1ewyFADFerredoxin--NADP reductase1.18.1.20.463
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.463
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.463
2fe4GDPRas-related protein Rab-6B/0.463
2r6jNDPEugenol synthase 11.1.1.3180.463
2vkeTACTetracycline repressor protein class D/0.463
2zscBTNTamavidin2/0.463
3h0vM2TS-adenosylmethionine decarboxylase proenzyme4.1.1.500.463
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.463
3qiyQI1Botulinum neurotoxin type A3.4.24.690.463
4azy7F3Beta-secretase 13.4.23.460.463
4b66NAPL-ornithine N(5)-monooxygenase/0.463
4bjbP34Tankyrase-22.4.2.300.463
4j3lAJ5Tankyrase-22.4.2.300.463
4jtrIBPAldo-keto reductase family 1 member C2/0.463
4kouC04Uncharacterized protein/0.463
4phlPILPhosphodiesterase/0.463
4u150HKMuscarinic acetylcholine receptor M3/0.463
1fmlRTLRetinol dehydratase/0.462
1nm6L86Prothrombin3.4.21.50.462
1queFADFerredoxin--NADP reductase1.18.1.20.462
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.462
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
2cleF6FTryptophan synthase alpha chain/0.462
2dxwSAHDiphthine synthase/0.462
2qe2452Polyprotein/0.462
2r6hFADNa(+)-translocating NADH-quinone reductase subunit F/0.462
2w6zL21Biotin carboxylase6.3.4.140.462
2znk31UProthrombin3.4.21.50.462
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3gwfNAPCyclohexanone monooxygenase/0.462
3h3r14HCollagen type IV alpha-3-binding protein/0.462
3ntqNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.462
3rthRTHBeta-secretase 13.4.23.460.462
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.462
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.462
4dd8BATDisintegrin and metalloproteinase domain-containing protein 83.4.240.462
4jtqFLPAldo-keto reductase family 1 member C2/0.462
4k6fNAPPutative Acetoacetyl-CoA reductase/0.462
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.462
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.462
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.462
1a8rGTPGTP cyclohydrolase 13.5.4.160.461
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
1ta2176Prothrombin3.4.21.50.461
1trgCB3Thymidylate synthase/0.461
2huvSAHDiphthine synthase/0.461
2j3qTFLAcetylcholinesterase3.1.1.70.461
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.461
2pcaSAHDiphthine synthase/0.461
2vdyHCYCorticosteroid-binding globulin/0.461
2zfq45UProthrombin3.4.21.50.461
3gn2AX8Pteridine reductase/0.461
3ho9N3A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.461
3vf60H6Glucokinase2.7.1.20.461
3w5uFADFerredoxin/0.461
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.461
4b4vL34Bifunctional protein FolD/0.461
4j0v1H7Beta-secretase 13.4.23.460.461
4jt91NSNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.461
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.461
4mv1ADPBiotin carboxylase6.3.4.140.461
4y0kNAPAntE/0.461
1c7oPPGHemolysin/0.460
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1hb1OCVIsopenicillin N synthase1.21.3.10.460
1kuyCOTSerotonin N-acetyltransferase/0.460
1pqc444Oxysterols receptor LXR-beta/0.460
2aouCQAHistamine N-methyltransferase2.1.1.80.460
2ay95PVAromatic-amino-acid aminotransferase2.6.1.570.460
2gv8NDPThiol-specific monooxygenase1.14.130.460
2vq7FADPutative flavin-containing monooxygenase/0.460
2zfp19UProthrombin3.4.21.50.460
2zjuIM4Acetylcholine-binding protein/0.460
3biv11UProthrombin3.4.21.50.460
3h2sNDPPutative NADH-flavin reductase/0.460
3qto10PProthrombin3.4.21.50.460
3rvhHQ2Lysine-specific demethylase 4A1.14.110.460
3swcSAHHistone-lysine N-methyltransferase EHMT1/0.460
3udn09BBeta-secretase 13.4.23.460.460
3w4k3LDD-amino-acid oxidase1.4.3.30.460
4bfsZVSPantothenate kinase2.7.1.330.460
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
4jq1NPSAldo-keto reductase family 1 member C2/0.460
4p9dTMPDeoxycytidylate deaminase/0.460
4to4DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.460
4uymVOR14-alpha sterol demethylase Cyp51B/0.460
1b2rFADFerredoxin--NADP reductase1.18.1.20.459
1bwsNDPGDP-L-fucose synthase/0.459
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.459
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.459
1zrb062Prothrombin3.4.21.50.459
2ejjSAHDiphthine synthase/0.459
2ejkSAHDiphthine synthase/0.459
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.459
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.459
2jgsBTNAvidin/0.459
2ovhAS0Progesterone receptor/0.459
2p6dSAHDiphthine synthase/0.459
3dz7O8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.459
3ihgVAKAklavinone 12-hydroxylase RdmE/0.459
3nn6HNK6-hydroxy-L-nicotine oxidase/0.459
3u4o08EGenome polyprotein2.7.7.480.459
3up0D7SaceDAF-12/0.459
4afeGGYSerine/threonine-protein kinase Nek22.7.11.10.459
4bj9UHBTankyrase-22.4.2.300.459
4e2wJHZMethyltransferase/0.459
4j0t6T9Beta-secretase 13.4.23.460.459
5bu2ADPUncharacterized protein/0.459
1dgfNDPCatalase1.11.1.60.458
1vbiNADMalate/L-lactate dehydrogenase family protein/0.458
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.458
1ywgNADGlyceraldehyde-3-phosphate dehydrogenase/0.458
2cjfRP43-dehydroquinate dehydratase4.2.1.100.458
2p9dSAHDiphthine synthase/0.458
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3ndjJHZMethyltransferase/0.458
3qeoLLTDeoxycytidine kinase2.7.1.740.458
3vo2FADFerredoxin--NADP reductase/0.458
3zv7NHGAcetylcholinesterase3.1.1.70.458
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.458
4b64NAPL-ornithine N(5)-monooxygenase/0.458
4b78KGGBeta-secretase 13.4.23.460.458
4g090VDHistidinol dehydrogenase/0.458
1dr5NAPDihydrofolate reductase1.5.1.30.457
1j4hSUBPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.457
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.457
1mxfMTXPutative pteridine reductase 2/0.457
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.457
1pq944BOxysterols receptor LXR-beta/0.457
1rszDIHPurine nucleoside phosphorylase2.4.2.10.457
1tllFMNNitric oxide synthase, brain1.14.13.390.457
1tsxUMPThymidylate synthase/0.457
2dshSAHDiphthine synthase/0.457
2e8rSAHDiphthine synthase/0.457
2ed5SAHDiphthine synthase/0.457
2ekaSAHDiphthine synthase/0.457
2pcgSAHDiphthine synthase/0.457
2w6pOA4Biotin carboxylase6.3.4.140.457
2xejOKDGlutamate carboxypeptidase 23.4.17.210.457
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.457
3hiiPNTAmiloride-sensitive amine oxidase [copper-containing]/0.457
3lqfNADGalactitol dehydrogenase/0.457
3o5rFK5Peptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.457
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3ug8IMNAldo-keto reductase family 1 member C3/0.457
4bs4A64Tankyrase-22.4.2.300.457
4du6GTPGTP cyclohydrolase 1/0.457
4f6w0SSCyclin-dependent kinase 82.7.11.220.457
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.457
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.457
4rvfTYDD-mycarose 3-C-methyltransferase/0.457
5dsyUHBPoly [ADP-ribose] polymerase 22.4.2.300.457
1f4fTP3Thymidylate synthase/0.456
1ny2ARG_PRO_PRO_GLYProthrombin3.4.21.50.456
1p0pBCHCholinesterase3.1.1.80.456
1zgv501Prothrombin3.4.21.50.456
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.456
2p2xSAHDiphthine synthase/0.456
2rh9IGPTryptophan synthase alpha chain/0.456
2x91LPRAngiotensin-converting enzyme3.4.15.10.456
2znoS44Peroxisome proliferator-activated receptor gamma/0.456
3kmxG00Beta-secretase 13.4.23.460.456
3sfh1DIHistone deacetylase 83.5.1.980.456
3v2uATPProtein GAL3/0.456
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.456
3zoiM2WIsopenicillin N synthase1.21.3.10.456
4ax8SAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.456
4ead0NPThymidine phosphorylase2.4.2.40.456
4k4fK4FTankyrase-12.4.2.300.456
4qa0SHHHistone deacetylase 83.5.1.980.456
4twnB96Ephrin type-A receptor 32.7.10.10.456
1amoFMNNADPH--cytochrome P450 reductase/0.455
1q45FMN12-oxophytodienoate reductase 31.3.1.420.455
1umaIN2Prothrombin3.4.21.50.455
1w51L01Beta-secretase 13.4.23.460.455
2c4iBTNAvidin/0.455
2dsgSAHDiphthine synthase/0.455
2dxvSAHDiphthine synthase/0.455
2egbSAHDiphthine synthase/0.455
2mokFMNFlavodoxin 1/0.455
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.455
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.455
2xvv9DNSerum albumin/0.455
3awhFMNFMN-binding protein/0.455
3bhrTHGThymidylate synthase/0.455
3dr7GPDGDP-perosamine synthase/0.455
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3pl8FADPyranose 2-oxidase/0.455
4b00I6XBeta-secretase 13.4.23.460.455
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
4mv8ACPBiotin carboxylase6.3.4.140.455
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.455
1d8fSPIStromelysin-13.4.24.170.454
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.454
1mmaADPMyosin-2 heavy chain/0.454
1pg2ADNMethionine--tRNA ligase6.1.1.100.454
1x1dSAHC-20 methyltransferase/0.454
1zeoC01Peroxisome proliferator-activated receptor gamma/0.454
2dg3RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.454
2e8hSAHDiphthine synthase/0.454
2flhZEACytokinin-specific binding protein/0.454
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.454
2qx7NAPEugenol synthase 11.1.1.3180.454
2vbpVB1Isopenicillin N synthase1.21.3.10.454
2y035FWBeta-1 adrenergic receptor/0.454
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.454
3csjCBLGlutathione S-transferase P2.5.1.180.454
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.454
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.454
3h0bB35Beta-secretase 13.4.23.460.454
3zsrO3NIntegrase/0.454
4acuQN7Beta-secretase 13.4.23.460.454
4cezO3NIntegrase/0.454
4fhd0TTSpore photoproduct lyase/0.454
4xnw2IDP2Y purinoceptor 1/0.454
3uonQNBMuscarinic acetylcholine receptor M2/0.454
1c4uIH1Prothrombin3.4.21.50.453
1dduCB3Thymidylate synthase/0.453
1dnpMHFDeoxyribodipyrimidine photo-lyase4.1.99.30.453
1dr3TAPDihydrofolate reductase1.5.1.30.453
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.453
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.453
2c42TPPPyruvate synthase/0.453
2g1n1IGRenin3.4.23.150.453
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.453
2p6kSAHDiphthine synthase/0.453
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.453
2rfiSAHHistone-lysine N-methyltransferase EHMT1/0.453
2ym1FADPhenylacetone monooxygenase1.14.13.920.453
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.453
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.453
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.453
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.453
3nx2FERFerulic acid decarboxylase/0.453
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.453
3zbtFADFerredoxin--NADP reductase1.18.1.20.453
4alxIZNAcetylcholine-binding protein/0.453
4dz5NAPAldo-keto reductase family 1 member C3/0.453
5hynSAHHistone-lysine N-methyltransferase EZH22.1.1.430.453
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.452
1l2sSTCBeta-lactamase3.5.2.60.452
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.452
1sqi8694-hydroxyphenylpyruvate dioxygenase/0.452
1vftDCSAlanine racemase/0.452
1w4lGL8Acetylcholinesterase3.1.1.70.452
1w6jR71Lanosterol synthase5.4.99.70.452
2b5oFADFerredoxin--NADP reductase1.18.1.20.452
2bn4FMNNADPH--cytochrome P450 reductase/0.452
2e08SAHDiphthine synthase/0.452
2eeqSAHDiphthine synthase/0.452
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.452
2jf0HBPAcetylcholinesterase3.1.1.70.452
2x7hPFNProstaglandin reductase 310.452
2xlrFADPutative flavin-containing monooxygenase/0.452
2zc922UProthrombin3.4.21.50.452
3eq02TSProthrombin3.4.21.50.452
3fznD7KBenzoylformate decarboxylase4.1.1.70.452
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.452
3hucG97Mitogen-activated protein kinase 14/0.452
3rl45GPMetallophosphoesterase MPPED23.10.452
3ske054Genome polyprotein2.7.7.480.452
4a83DXCMajor pollen allergen Bet v 1-A/0.452
4acxS8ZBeta-secretase 13.4.23.460.452
4bfpSWYTankyrase-22.4.2.300.452
4cukNAID-lactate dehydrogenase/0.452
4flkY10Methionine aminopeptidase 1/0.452
4h6pFMNChromate reductase/0.452
5c1gGDUHisto-blood group ABO system transferase/0.452
1afeALZProthrombin3.4.21.50.451
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.451
1by5GLY_GLY_GLY_AHO_AHO_AHO_FEFerrichrome-iron receptor/0.451
1fkjFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.451
1gj5130Prothrombin3.4.21.50.451
1gpnHUBAcetylcholinesterase3.1.1.70.451
1n6lGTPRas-related protein Rab-5A/0.451
1qtqQSIGlutamine--tRNA ligase6.1.1.180.451
1wm1PTBProline iminopeptidase3.4.11.50.451
1yryMSGPurine nucleoside phosphorylase2.4.2.10.451
1yw8A75Methionine aminopeptidase 2/0.451
2bvs2CEProthrombin3.4.21.50.451
2ed3SAHDiphthine synthase/0.451
2el0SAHDiphthine synthase/0.451
2eldSAHDiphthine synthase/0.451
2fxuBIDActin, alpha skeletal muscle/0.451
2hizLIJBeta-secretase 13.4.23.460.451
2pchSAHDiphthine synthase/0.451
2qxxTTPdCTP deaminase3.5.4.130.451
2w71L23Biotin carboxylase6.3.4.140.451
2xysSY9Soluble acetylcholine receptor/0.451
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.451
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3h2lYAKGenome polyprotein2.7.7.480.451
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3qgi33FGenome polyprotein2.7.7.480.451
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.451
3s8pSAMHistone-lysine N-methyltransferase KMT5B2.1.1.430.451
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.451
4d89BXDBeta-secretase 13.4.23.460.451
4xo7ASDAldo-keto reductase family 1 member C2/0.451
5dv2C5PCCR4-NOT transcription complex subunit 6-like3.1.13.40.451
5iosFADFlavin-dependent thymidylate synthase2.1.1.1480.451
1d6w00RProthrombin3.4.21.50.450
1fwmCB3Thymidylate synthase/0.450
1j37X8ZAngiotensin-converting enzyme3.4.15.10.450
1mc0PCGcGMP-dependent 3',5'-cyclic phosphodiesterase/0.450
1ot7IU5Bile acid receptor/0.450
1qjfACSIsopenicillin N synthase1.21.3.10.450
1ypmRA4Prothrombin3.4.21.50.450
1yzqGNPRas-related protein Rab-6A/0.450
2fr1NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.450
2pj4414Carboxypeptidase B/0.450
2whqHI6Acetylcholinesterase3.1.1.70.450
2xujTZ5Acetylcholinesterase3.1.1.70.450
2xvhFADPutative flavin-containing monooxygenase/0.450
3bi4298Polyamine oxidase FMS1/0.450
3f0aACOSpermidine N(1)-acetyltransferase/0.450
3iaaTYDCalG2/0.450
3kej3EJCollagenase 33.4.240.450
3oqkS52Renin3.4.23.150.450
3pkaY02Methionine aminopeptidase 2/0.450
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.450
4a81DXCMajor pollen allergen Bet v 1-A/0.450
4baoMVFProthrombin3.4.21.50.450
4hh4SAHCcbJ/0.450
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.450
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.450
4z4pSAHHistone-lysine N-methyltransferase 2D2.1.1.430.450
1dr2TAPDihydrofolate reductase1.5.1.30.449
1gveNAPAflatoxin B1 aldehyde reductase member 310.449
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.449
1jdvADNPurine nucleoside phosphorylase/0.449
1ogjFADFerredoxin--NADP reductase1.18.1.20.449
1pd9CO4Dihydrofolate reductase1.5.1.30.449
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.449
2cmfF11Acetylcholinesterase3.1.1.70.449
2e15SAHDiphthine synthase/0.449
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.449
2watCOAFatty acid synthase subunit alpha2.3.1.860.449
3bgxMEFThymidylate synthase/0.449
3g6zA7TRenin3.4.23.150.449
3kmyD8YBeta-secretase 13.4.23.460.449
3mauEXTPutative sphingosine-1-phosphate lyase/0.449
3p74FMNPentaerythritol tetranitrate reductase/0.449
3rsv3RSBeta-secretase 13.4.23.460.449
3wipACHAcetylcholine-binding protein/0.449
4jq2SUZAldo-keto reductase family 1 member C2/0.449
1acjTHAAcetylcholinesterase3.1.1.70.448
1clqGDPDNA-directed DNA polymerase/0.448
1fkhSBXPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.448
1h5nPGDDimethyl sulfoxide/trimethylamine N-oxide reductase1.7.2.30.448
1h85FADFerredoxin--NADP reductase1.18.1.20.448
1m9m6NINitric oxide synthase, endothelial1.14.13.390.448
1mu6CDAProthrombin3.4.21.50.448
1muuGDXGDP-mannose 6-dehydrogenase1.1.1.1320.448
1n5dNDPCarbonyl reductase [NADPH] 1/0.448
1njcDCMThymidylate synthase/0.448
1o2eANNPhospholipase A23.1.1.40.448
1obnASVIsopenicillin N synthase1.21.3.10.448
1rkwPNTHTH-type transcriptional regulator QacR/0.448
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.448
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.448
2b36NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2b99RDLRiboflavin synthase2.5.1.90.448
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.448
2gz7D3FOrf1a polyprotein/0.448
2zjnF1NBeta-secretase 13.4.23.460.448
2zvbSAHPrecorrin-3 C17-methyltransferase/0.448
3a20FMNFMN-binding protein/0.448
3c0zSHHHistone deacetylase 73.5.1.980.448
3friSAH16S rRNA methylase/0.448
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.448
3ig6438Urokinase-type plasminogen activator3.4.21.730.448
3kkoGNPRas-related protein M-Ras/0.448
3lkhLT6Genome polyprotein2.7.7.480.448
3mjhGTPRas-related protein Rab-5A/0.448
3qwbNDPProbable quinone oxidoreductase1.6.5.50.448
4d03FADPhenylacetone monooxygenase1.14.13.920.448
4e31JHZMethyltransferase/0.448
4fuiUI3Urokinase-type plasminogen activator3.4.21.730.448
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.448
4jicFMNGTN Reductase/0.448
4xzjNADPutative NAD(+)--arginine ADP-ribosyltransferase Vis2.4.2.310.448
5arkUMPRibonuclease 43.1.270.448
1ja0FMNNADPH--cytochrome P450 reductase/0.447
1puaCOAHAT A1/0.447
1rjgSAHLeucine carboxyl methyltransferase 12.1.1.2330.447
1rxjBNIStreptavidin/0.447
1s3uTQDDihydrofolate reductase1.5.1.30.447
1t7o152Carnitine O-acetyltransferase2.3.1.70.447
1t91GTPRas-related protein Rab-7a/0.447
1umcTDP2-oxoisovalerate dehydrogenase subunit alpha1.2.4.40.447
1umcTDP2-oxoisovalerate dehydrogenase subunit beta1.2.4.40.447
2abaSTRPentaerythritol tetranitrate reductase/0.447
2abbFMNPentaerythritol tetranitrate reductase/0.447
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.447
2an9GDPGuanylate kinase2.7.4.80.447
2bdzE64Mexicain3.4.220.447
2cbjOANO-GlcNAcase NagJ/0.447
2e94364Geranylgeranyl pyrophosphate synthase/0.447
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.447
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.447
2ffqGSPRas-related protein Rab-6B/0.447
2fj1CTCTetracycline repressor protein class D/0.447
2hutSAHDiphthine synthase/0.447
2iviACWIsopenicillin N synthase1.21.3.10.447
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.447
2owvSAHDiphthine synthase/0.447
2p2qPRXAcetyl-coenzyme A synthetase/0.447
3bwcSAMSpermidine synthase, putative/0.447
3csoXNIGenome polyprotein2.7.7.480.447
3fhxPLPPyridoxal kinase2.7.1.350.447
3gsiTHGDimethylglycine oxidase1.5.3.100.447
3h3qH13Collagen type IV alpha-3-binding protein/0.447
3oadLPORenin3.4.23.150.447
3ojwFMNNADPH--cytochrome P450 reductase/0.447
3qt62P0Mevalonate diphosphate decarboxylase/0.447
3tq8TOPDihydrofolate reductase/0.447
3vjlW94Dipeptidyl peptidase 4/0.447
4baqM4ZProthrombin3.4.21.50.447
4imfSI3N-acetylneuraminate lyase/0.447
4j6dTESCytochrome P450 monooxygenase/0.447
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.447
4q4kFMNUncharacterized protein/0.447
4wljIK2Kynurenine--oxoglutarate transaminase 12.6.1.70.447
4xr9NADCalS8/0.447
4y7cFADNADPH--cytochrome P450 reductase/0.447
4u163C0Muscarinic acetylcholine receptor M3/0.447
1ci7UMPThymidylate synthase2.1.1.450.446
1i7mCGS-adenosylmethionine decarboxylase proenzyme4.1.1.500.446
1mczRMNBenzoylformate decarboxylase4.1.1.70.446
1qpf858Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.446
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.446
1tu8GTXGlutathione S-transferase 22.5.1.180.446
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.446
1ypjUIBProthrombin3.4.21.50.446
2aa71CAMineralocorticoid receptor/0.446
2aclL05Oxysterols receptor LXR-alpha/0.446
2cntCOARibosomal-protein-alanine acetyltransferase/0.446
2eh2SAHDiphthine synthase/0.446
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2hr8SAHDiphthine synthase/0.446
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2ociTYCValacyclovir hydrolase3.10.446
2r0pK2CPutative FAD-monooxygenase/0.446
2uuk897Prothrombin3.4.21.50.446
2xlpNAPPutative flavin-containing monooxygenase/0.446
3bbpGTPRas-related protein Rab-6A/0.446
3dz6M8ES-adenosylmethionine decarboxylase proenzyme4.1.1.500.446
3f3y4OABile salt sulfotransferase2.8.2.140.446
3f4bTCLEnoyl-acyl carrier protein reductase/0.446
3geyP34Poly [ADP-ribose] polymerase 152.4.2.300.446
3h59H59Genome polyprotein2.7.7.480.446
3lpkZ76Beta-secretase 13.4.23.460.446
3nd6ATPPhosphopantetheine adenylyltransferase/0.446
3ojxFADNADPH--cytochrome P450 reductase/0.446
3rdqDTBStreptavidin/0.446
3udq09EBeta-secretase 13.4.23.460.446
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.446
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.446
4cfc7NVIntegrase/0.446
4dk70KSOxysterols receptor LXR-beta/0.446
4eji0QACytochrome P450 2A131.14.14.10.446
4enhFVXCholesterol 24-hydroxylase/0.446
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.446
4glx0XSDNA ligase6.5.1.20.446
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.446
4opuFDAConserved Archaeal protein/0.446
4rrrA3TThreonine--tRNA ligase6.1.1.30.446
4uugPXGBranched-chain amino acid aminotransferase, putative/0.446
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.446
1aa6MGDFormate dehydrogenase H1.1.99.330.445
1cjtFOKAdenylate cyclase type 2/0.445
1cjtFOKAdenylate cyclase type 5/0.445
1fndFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.445
1frbZSTAldose reductase-related protein 2/0.445
1mrqSTRAldo-keto reductase family 1 member C1/0.445
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
1toiHCIAspartate aminotransferase2.6.1.10.445
1uumFMNDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.445
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.445
1zxlJP1Enoyl-ACP reductase/0.445
2bt4CA23-dehydroquinate dehydratase4.2.1.100.445
2egsSAHDiphthine synthase/0.445
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.445
2gyuHI6Acetylcholinesterase3.1.1.70.445
2lfoGCHFatty acid-binding protein, liver/0.445
2pciSAHDiphthine synthase/0.445
2qw8NAPEugenol synthase 11.1.1.3180.445
2uxoTACHTH-type transcriptional regulator TtgR/0.445
2vijC44Beta-secretase 13.4.23.460.445
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.445
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.445
3hl0NADMaleylacetate reductase/0.445
3k5dXLIBeta-secretase 13.4.23.460.445
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.445
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.445
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
4arbC57Acetylcholinesterase3.1.1.70.445
4bfzZVZPantothenate kinase2.7.1.330.445
4f5yC2EStimulator of interferon genes protein/0.445
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4hfp15UProthrombin3.4.21.50.445
4jqaID8Aldo-keto reductase family 1 member C2/0.445
4qa2SHHHistone deacetylase 83.5.1.980.445
4uajFADNa(+)-translocating NADH-quinone reductase subunit F/0.445
4xvrGNPGTPase HRas/0.445
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.445
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.445
1d2hSAHGlycine N-methyltransferase2.1.1.200.444
1dr3HBIDihydrofolate reductase1.5.1.30.444
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.444
1mvsDTMDihydrofolate reductase1.5.1.30.444
1o6qR17Squalene--hopene cyclase4.2.1.1290.444
1oz0MS1Bifunctional purine biosynthesis protein PURH2.1.2.30.444
1xyyFMNFlavodoxin/0.444
1z5vGSPTubulin gamma-1 chain/0.444
1z7yAA5Cysteine synthase 12.5.1.470.444
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.444
2aovC2MHistamine N-methyltransferase2.1.1.80.444
2eh4SAHDiphthine synthase/0.444
2ek2SAHDiphthine synthase/0.444
2hxdDUPdCTP deaminase, dUMP-forming3.5.4.300.444
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.444
2j62GSZO-GlcNAcase NagJ/0.444
2pb5SAHDiphthine synthase/0.444
2q3eNAIUDP-glucose 6-dehydrogenase1.1.1.220.444
3cic316Beta-secretase 13.4.23.460.444
3e39FMNNitroreductase/0.444
3f63GTXGlutathione transferase GST1-4/0.444
3gnvXNZGenome polyprotein2.7.7.480.444
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3pkbY16Methionine aminopeptidase 2/0.444
3r2fPB0Beta-secretase 13.4.23.460.444
3u8n09SAcetylcholine-binding protein/0.444
3zv5BPYCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.444
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.444
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.444
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.444
4gd40WSLysine-specific demethylase 4A1.14.110.444
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.444
4j3mAJ8Tankyrase-22.4.2.300.444
4req5ADMethylmalonyl-CoA mutase large subunit5.4.99.20.444
4xq9NADHomospermidine synthase2.5.1.440.444
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.444
5cxv0HKMuscarinic acetylcholine receptor M1/0.444
1a4wQWEProthrombin3.4.21.50.443
1bkfFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.443
1c9wNAPAldose reductase-related protein 2/0.443
1gky5GPGuanylate kinase2.7.4.80.443
1j9zFADNADPH--cytochrome P450 reductase/0.443
1krrACOGalactoside O-acetyltransferase2.3.1.180.443
1mepBTNStreptavidin/0.443
1nbiSAMGlycine N-methyltransferase2.1.1.200.443
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.443
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.443
1ogiFADFerredoxin--NADP reductase1.18.1.20.443
1swpBTNStreptavidin/0.443
1t2cNAIL-lactate dehydrogenase1.1.1.270.443
1u1jC2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 12.1.1.140.443
1xagNAD3-dehydroquinate synthase/0.443
1xm1GAHProthrombin3.4.21.50.443
2dekSAHDiphthine synthase/0.443
2g0gSP0Peroxisome proliferator-activated receptor gamma/0.443
2g247IGRenin3.4.23.150.443
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.443
2g263LGRenin3.4.23.150.443
2ij7TPFMycocyclosin synthase1.14.21.90.443
2p2jPRXAcetyl-coenzyme A synthetase/0.443
3b6pTMPThree-prime repair exonuclease 13.1.11.20.443
3fhxPXLPyridoxal kinase2.7.1.350.443
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
3p82FMNPentaerythritol tetranitrate reductase/0.443
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.443
3wquATPCell division protein FtsA/0.443
4biwANPSensor histidine kinase CpxA/0.443
4g67SAHUncharacterized ACR, COG1565 superfamily/0.443
4idpGNPAtlastin-13.6.50.443
4jv3N32Beta-ketoacyl synthase/0.443
4l5b1UXDeoxycytidine kinase2.7.1.740.443
4nbuCAA3-oxoacyl-(Acyl-carrier-protein) reductase/0.443
4o6fSAHN-lysine methyltransferase SMYD2/0.443
4qofFMNRibosyldihydronicotinamide dehydrogenase [quinone]/0.443
4rxqDUTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.443
4yfy1YJVioF/0.443
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.443
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.443
4u140HKMuscarinic acetylcholine receptor M3/0.443
1bk0ACVIsopenicillin N synthase1.21.3.10.442
1cs4FOKAdenylate cyclase type 2/0.442
1cs4FOKAdenylate cyclase type 5/0.442
1e66HUXAcetylcholinesterase3.1.1.70.442
1gj4132Prothrombin3.4.21.50.442
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.442
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1ihiIU5Aldo-keto reductase family 1 member C2/0.442
1ja1FMNNADPH--cytochrome P450 reductase/0.442
1m9jCLWNitric oxide synthase, endothelial1.14.13.390.442
1po7TZDBenzoylformate decarboxylase4.1.1.70.442
1r00SAHAclacinomycin 10-hydroxylase RdmB4.1.10.442
1u65CP0Acetylcholinesterase3.1.1.70.442
2bf4FADNADPH--cytochrome P450 reductase/0.442
2g21L1BRenin3.4.23.150.442
2gevCOKPantothenate kinase2.7.1.330.442
2nr4FMNConserved protein/0.442
2pswCOAN-alpha-acetyltransferase 50/0.442
2uxhQUEHTH-type transcriptional regulator TtgR/0.442
2wm3NFLNmrA-like family domain-containing protein 1/0.442
2xupTZ5Acetylcholinesterase3.1.1.70.442
2zevIPEGeranylgeranyl pyrophosphate synthase/0.442
2zi224UProthrombin3.4.21.50.442
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.442
3b1dPLSBetaC-S lyase/0.442
3dt2GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.442
3f8wADNPurine nucleoside phosphorylase/0.442
3hatGLY_VAL_ARG_RNGProthrombin3.4.21.50.442
3i7g732Collagenase 33.4.240.442
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.442
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.442
3w3zGTPGTP-binding nuclear protein Ran/0.442
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.442
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.442
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.442
4bfq083Soluble acetylcholine receptor/0.442
4bjcRPBTankyrase-22.4.2.300.442
4d9eLCSD-cysteine desulfhydrase/0.442
4dh60KNBeta-secretase 13.4.23.460.442
4dq1UMPThymidylate synthase/0.442
4fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.442
4fapARDSerine/threonine-protein kinase mTOR2.7.11.10.442
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.442
4l33F70Tankyrase-22.4.2.300.442
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.442
4q71FADBifunctional protein PutA/0.442
4rrwLURProstaglandin G/H synthase 21.14.99.10.442
4rrzLURProstaglandin G/H synthase 21.14.99.10.442
4ua3COAN-alpha-acetyltransferase 402.3.10.442
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
4xrbNDPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.442
1flmFMNFMN-binding protein/0.441
1h74ADPHomoserine kinase2.7.1.390.441
1h8hATPATP synthase subunit alpha, mitochondrial/0.441
1h8hATPATP synthase subunit beta, mitochondrial3.6.3.140.441
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1lcbTMPThymidylate synthase/0.441
1q13TESProstaglandin-E(2) 9-reductase1.1.1.1890.441
1s17GNRPeptide deformylase/0.441
1sm4FADFerredoxin--NADP reductase/0.441
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.441
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
2igqSAHHistone-lysine N-methyltransferase EHMT1/0.441
2jb4A14Isopenicillin N synthase1.21.3.10.441
2oazI96Methionine aminopeptidase 2/0.441
2owkSAHDiphthine synthase/0.441
2x9vTMQPteridine reductase/0.441
2xuoTZ4Acetylcholinesterase3.1.1.70.441
2zevB71Geranylgeranyl pyrophosphate synthase/0.441
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.441
3cukFADD-amino-acid oxidase1.4.3.30.441
3frkTQPQdtB/0.441
3g1oRF1HTH-type transcriptional regulator EthR/0.441
3ivgFG5Pantothenate synthetase6.3.2.10.441
3owj1ELCasein kinase II subunit alpha2.7.11.10.441
3phiNDPShikimate dehydrogenase (NADP(+))/0.441
3q9bB3NAcetylpolyamine amidohydrolase/0.441
3wleNAD(R)-specific carbonyl reductase/0.441
4a8v2ANMajor pollen allergen Bet v 1-J/0.441
4b0qGMFBeta-secretase 13.4.23.460.441
4ck2NVUIntegrase/0.441
4cojCTPUncharacterized protein/0.441
4eueNAITrans-2-enoyl-CoA reductase [NADH]/0.441
4i0h1BLBeta-secretase 13.4.23.460.441
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.441
4lutDCSAlanine racemase/0.441
4tqoPQQMethanol dehydrogenase protein, large subunit/0.441
4ts7ADPPurine phosphoribosyltransferase (GpT-1)/0.441
4wbdADPPutative cysteine ligase BshC/0.441
4zgsNADPutative D-lactate dehydrogenase/0.441
5ah5LSSLeucine--tRNA ligase/0.441
1lc3NADBiliverdin reductase A1.3.1.240.440
1lceTMFThymidylate synthase/0.440
1m78NDPDihydrofolate reductase1.5.1.30.440
1nbhSAMGlycine N-methyltransferase2.1.1.200.440
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.440
1qy2IPZMajor urinary protein 1/0.440
1towCRZFatty acid-binding protein, adipocyte/0.440
1vyrFMNPentaerythritol tetranitrate reductase/0.440
1yhjR6CPyridoxal kinase2.7.1.350.440
2aqbTL63-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.440
2gvvDI9Diisopropyl-fluorophosphatase3.1.8.20.440
2pdaTPPPyruvate synthase/0.440
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.440
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.440
2wd9IBPAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.440
2y1w849Histone-arginine methyltransferase CARM1/0.440
2zxgS23Aminopeptidase N3.4.11.20.440
3a26MTAtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.440
3dgaUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.440
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.440
3ekuCY9Actin-5C/0.440
3fvlBHKCarboxypeptidase A13.4.17.10.440
3h3t16HCollagen type IV alpha-3-binding protein/0.440
3nrcTCLEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
3nutSAHPrecorrin-3 methylase/0.440
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
3pm1ETHTH-type transcriptional regulator QacR/0.440
3pvcFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.440
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.440
3qvrFADGlucose oxidase1.1.3.40.440
3t6iNC8Endothiapepsin3.4.23.220.440
3to3ATPPetrobactin biosynthesis protein AsbB/0.440
4b0532DBeta-secretase 13.4.23.460.440
4ey6GNTAcetylcholinesterase3.1.1.70.440
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.440
4hlm16STankyrase-22.4.2.300.440
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.440
4mk928RGenome polyprotein2.7.7.480.440
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.440
4oztP1AEcdysone receptor, putative/0.440
4pghSAMCaffeic acid O-methyltransferase/0.440
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.440
4z87GDPInosine-5'-monophosphate dehydrogenase/0.440
5cflC2EStimulator of interferon genes protein/0.440
5ero210Fusicoccadiene synthase2.5.1.290.440
6coxS58Prostaglandin G/H synthase 21.14.99.10.440