Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4hnf16WCasein kinase I isoform delta2.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4hnf16WCasein kinase I isoform delta2.7.11.11.000
3uyt0CKCasein kinase I isoform delta2.7.11.10.587
4kbk1QGCasein kinase I isoform delta2.7.11.10.587
4kb81QNCasein kinase I isoform delta2.7.11.10.555
2izrBRKCasein kinase I isoform gamma-32.7.11.10.545
4yuqKS1Calmodulin-like domain protein kinase/0.543
4i22IREEpidermal growth factor receptor2.7.10.10.538
4hni16WCasein kinase I isoform epsilon2.7.11.10.537
1eh4IC1Casein kinase I homolog 12.7.11.10.535
4g170VNCasein kinase I isoform gamma-32.7.11.10.532
4kba1QMCasein kinase I isoform delta2.7.11.10.530
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.529
3uzp0CKCasein kinase I isoform delta2.7.11.10.528
3gubGUBDeath-associated protein kinase 12.7.11.10.526
2wotZZGTGF-beta receptor type-12.7.11.300.523
3gxlQIGTGF-beta receptor type-12.7.11.300.523
3fln3FNMitogen-activated protein kinase 14/0.521
2izsBRQCasein kinase I isoform gamma-32.7.11.10.511
2b1pAIZMitogen-activated protein kinase 102.7.11.240.508
3mtfA3FActivin receptor type-12.7.11.300.508
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.506
3ttjJBIMitogen-activated protein kinase 102.7.11.240.506
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.506
1bygSTUTyrosine-protein kinase CSK/0.505
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.505
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.505
1u4dDBQActivated CDC42 kinase 1/0.503
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.503
4ic7ANPMitogen-activated protein kinase 72.7.11.240.503
2o0uC0MMitogen-activated protein kinase 102.7.11.240.501
4lopSB4Mitogen-activated protein kinase 14/0.501
5e8wSTUTGF-beta receptor type-12.7.11.300.501
1csnATPCasein kinase I homolog 12.7.11.10.500
4loqSB4Mitogen-activated protein kinase 14/0.500
4dymIYZActivin receptor type-12.7.11.300.499
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.497
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.497
3mvl38PMitogen-activated protein kinase 14/0.497
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.497
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.496
4c4jX21Dual specificity protein kinase TTK2.7.12.10.496
4riyADPEpidermal growth factor receptor2.7.10.10.495
4bgg844Activin receptor type-12.7.11.300.493
3gc9B45Mitogen-activated protein kinase 112.7.11.240.492
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.490
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.489
2iw94SPCyclin-dependent kinase 22.7.11.220.489
2j0lANPFocal adhesion kinase 12.7.10.20.489
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.489
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.489
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.489
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.488
3hl7I47Mitogen-activated protein kinase 14/0.488
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.488
3gu83GUDeath-associated protein kinase 12.7.11.10.487
4ewqMWLMitogen-activated protein kinase 14/0.487
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.487
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.486
4kb81QOCasein kinase I isoform delta2.7.11.10.486
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.485
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.485
3kf7L9GMitogen-activated protein kinase 14/0.485
3w33W19Epidermal growth factor receptor2.7.10.10.485
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.485
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.485
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.484
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.484
2excJNKMitogen-activated protein kinase 102.7.11.240.483
2iw84SPCyclin-dependent kinase 22.7.11.220.483
4eok4SPCyclin-dependent kinase 22.7.11.220.483
4eor4SPCyclin-dependent kinase 22.7.11.220.483
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.483
1h1s4SPCyclin-dependent kinase 22.7.11.220.482
1oiyN41Cyclin-dependent kinase 22.7.11.220.482
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.482
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.482
4g160VMCasein kinase I isoform gamma-32.7.11.10.482
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.482
1gih1PUCyclin-dependent kinase 22.7.11.220.481
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.481
3mpaSB2Mitogen-activated protein kinase 14/0.481
3roc29AMitogen-activated protein kinase 14/0.481
4hgt15GCasein kinase I isoform delta2.7.11.10.481
1oi9N20Cyclin-dependent kinase 22.7.11.220.480
3c50ADPRhodopsin kinase/0.480
3oqkS52Renin3.4.23.150.480
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.480
3ttiKBIMitogen-activated protein kinase 102.7.11.240.480
2x1nX1NCyclin-dependent kinase 22.7.11.220.479
2zdt46CMitogen-activated protein kinase 102.7.11.240.479
4zseANPEpidermal growth factor receptor2.7.10.10.479
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.478
3zewSTUEphrin type-B receptor 42.7.10.10.478
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.478
4ih8B43Calmodulin-domain protein kinase 1/0.478
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.477
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.477
3hmm855TGF-beta receptor type-12.7.11.300.477
3sheI85MAP kinase-activated protein kinase 32.7.11.10.477
2ckeIQUDeath-associated protein kinase 2/0.476
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.476
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.476
2ittAEEEpidermal growth factor receptor2.7.10.10.475
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.475
3bu5ATPInsulin receptor2.7.10.10.475
3nww3NWMitogen-activated protein kinase 14/0.475
1ywrLI9Mitogen-activated protein kinase 14/0.474
2j0k4STFocal adhesion kinase 12.7.10.20.474
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.474
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.474
4aacAAVMitogen-activated protein kinase 14/0.474
4ez50RSCyclin-dependent kinase 62.7.11.220.474
4kiq1RAMitogen-activated protein kinase 14/0.474
1vjy460TGF-beta receptor type-12.7.11.300.473
2ghmLICMitogen-activated protein kinase 14/0.473
3flsFLSMitogen-activated protein kinase 14/0.473
3igoANPCalmodulin-domain protein kinase 1, putative/0.473
4bcoT6QCyclin-dependent kinase 22.7.11.220.473
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.473
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.472
4c4h7RODual specificity protein kinase TTK2.7.12.10.472
4f650S9Fibroblast growth factor receptor 1/0.472
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.472
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.471
4fv9E71Mitogen-activated protein kinase 12.7.11.240.471
4gk2L66Ephrin type-A receptor 32.7.10.10.471
1ir3ANPInsulin receptor2.7.10.10.470
1k6cMK1Gag-Pol polyprotein3.4.23.160.470
2w05FRTCyclin-dependent kinase 22.7.11.220.470
1u54ACPActivated CDC42 kinase 1/0.469
1v0pPVBCell division control protein 2 homolog2.7.11.220.469
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.469
3oom507Activin receptor type-12.7.11.300.469
3ormAGSSerine/threonine protein kinase/0.469
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.469
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.469
4bcmT7ZCyclin-dependent kinase 22.7.11.220.469
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.469
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.469
4xhgADPUncharacterized protein/0.469
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
1k6tXN1Gag-Pol polyprotein3.4.23.160.468
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.468
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.468
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.468
3s2pPMUCyclin-dependent kinase 22.7.11.220.468
4c02TAKActivin receptor type-12.7.11.300.468
4e4m0NHTyrosine-protein kinase JAK2/0.468
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.468
4fx360KCyclin-dependent kinase 22.7.11.220.468
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
3l8p0CEAngiopoietin-1 receptor2.7.10.10.467
4aa4QC0Mitogen-activated protein kinase 14/0.467
4c4f7CEDual specificity protein kinase TTK2.7.12.10.467
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.467
4ux9ANPMitogen-activated protein kinase 82.7.11.240.467
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.467
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.467
1k6pXN3Gag-Pol polyprotein3.4.23.160.466
1zyjBI5Mitogen-activated protein kinase 14/0.466
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.466
3a4pDFQHepatocyte growth factor receptor2.7.10.10.466
3a62STURibosomal protein S6 kinase beta-12.7.11.10.466
3hvcGG5Mitogen-activated protein kinase 14/0.466
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.466
4kbc1QJCasein kinase I isoform delta2.7.11.10.466
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.466
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.466
4qmzB49Serine/threonine-protein kinase 242.7.11.10.466
1xjdSTUProtein kinase C theta type2.7.11.130.465
2etm7PYFocal adhesion kinase 12.7.10.20.465
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.465
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.465
3vs1VSATyrosine-protein kinase HCK2.7.10.20.465
4jq8KJ8Epidermal growth factor receptor2.7.10.10.465
4nk92K5Fibroblast growth factor receptor 1/0.465
4qmpDKISerine/threonine-protein kinase 242.7.11.10.465
5auwQUEDeath-associated protein kinase 12.7.11.10.465
1rw8580TGF-beta receptor type-12.7.11.300.464
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.464
2jedLG8Protein kinase C theta type2.7.11.130.464
3qu0X40Cyclin-dependent kinase 22.7.11.220.464
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.464
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.464
3umw596Serine/threonine-protein kinase pim-12.7.11.10.464
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.464
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.464
4b99R4LMitogen-activated protein kinase 72.7.11.240.464
4hvi19STyrosine-protein kinase JAK32.7.10.20.464
4nks2M2Fibroblast growth factor receptor 1/0.464
5cvhADPCasein kinase II subunit alpha2.7.11.10.464
1aq1STUCyclin-dependent kinase 22.7.11.220.463
1di8DTQCyclin-dependent kinase 22.7.11.220.463
1g5sI17Cyclin-dependent kinase 22.7.11.220.463
1gqtACPRibokinase/0.463
2q59240Peroxisome proliferator-activated receptor gamma/0.463
2vwy7X5Ephrin type-B receptor 42.7.10.10.463
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.463
3rk507ZCyclin-dependent kinase 22.7.11.220.463
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.463
1p4fDRGDeath-associated protein kinase 12.7.11.10.462
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.462
2pvnP63Casein kinase II subunit alpha2.7.11.10.462
3ddpRC8Cyclin-dependent kinase 22.7.11.220.462
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.462
4hgs15GCasein kinase I isoform gamma-32.7.11.10.462
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.462
1ie3NADMalate dehydrogenase/0.461
2btsU32Cyclin-dependent kinase 22.7.11.220.461
2itnANPEpidermal growth factor receptor2.7.10.10.461
2itpAEEEpidermal growth factor receptor2.7.10.10.461
2vww7X2Ephrin type-B receptor 42.7.10.10.461
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.461
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.461
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.461
3nwq2NCGag-Pol polyprotein3.4.23.160.461
3nwxKVSGag-Pol polyprotein3.4.23.160.461
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4cfnJYMCyclin-dependent kinase 22.7.11.220.461
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.461
2c475IDCasein kinase I isoform gamma-2/0.460
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.460
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.460
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.460
3fi3JK2Mitogen-activated protein kinase 102.7.11.240.460
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.460
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.460
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.460
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.460
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.460
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.459
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.459
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.459
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.459
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.459
3b6zCO7Enoyl reductase LovC10.459
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.459
3fmjFMJMitogen-activated protein kinase 14/0.459
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.459
3qaiXNNKetohexokinase/0.459
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.459
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
5ap57RODual specificity protein kinase TTK2.7.12.10.459
5dpvSKEAurora kinase A2.7.11.10.459
1h1r6CPCyclin-dependent kinase 22.7.11.220.458
1wbmBLLPol protein/0.458
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.458
2ghlLIBMitogen-activated protein kinase 14/0.458
2wouZZFTGF-beta receptor type-12.7.11.300.458
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.458
3tmz06XCytochrome P450 2B41.14.14.10.458
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.458
4eh60ONMitogen-activated protein kinase 14/0.458
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.458
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.458
4wboANWRhodopsin kinase/0.458
1oiuN76Cyclin-dependent kinase 22.7.11.220.457
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.457
2qo9ANPEphrin type-A receptor 32.7.10.10.457
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.457
2xrwANPMitogen-activated protein kinase 82.7.11.240.457
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.457
3dt1P40Mitogen-activated protein kinase 14/0.457
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.457
4eoi1ROCyclin-dependent kinase 22.7.11.220.457
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.457
4o0wADNAurora kinase A2.7.11.10.457
4qbjNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.457
1jpaANPEphrin type-B receptor 22.7.10.10.456
2chlDKICasein kinase I isoform gamma-32.7.11.10.456
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.456
3fmkFMKMitogen-activated protein kinase 14/0.456
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.456
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.456
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2j0m4STFocal adhesion kinase 12.7.10.20.455
2vwz7X6Ephrin type-B receptor 42.7.10.10.455
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.455
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
3fklFKLMitogen-activated protein kinase 14/0.455
3ggfGVDSerine/threonine-protein kinase 26/0.455
3my5RFZCyclin-dependent kinase 22.7.11.220.455
3q92XNBKetohexokinase/0.455
3uvqFS8Mitogen-activated protein kinase 14/0.455
4ia2BIVVitamin D3 receptor A/0.455
4kip1R9Mitogen-activated protein kinase 14/0.455
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.455
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.455
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.454
2dfvNADL-threonine 3-dehydrogenase/0.454
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.454
2pz5ACPFibroblast growth factor receptor 2/0.454
2uzlC94Cyclin-dependent kinase 22.7.11.220.454
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.454
3ddqRRCCyclin-dependent kinase 22.7.11.220.454
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.454
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.454
4fv7E94Mitogen-activated protein kinase 12.7.11.240.454
4hvh19RTyrosine-protein kinase JAK32.7.10.20.454
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.454
4mwhATPCasein kinase II subunit alpha2.7.11.10.454
4ogrADNCyclin-dependent kinase 92.7.11.220.454
4pkl1GHUncharacterized protein/0.454
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.454
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.453
2hog710Serine/threonine-protein kinase Chk12.7.11.10.453
2itqITQEpidermal growth factor receptor2.7.10.10.453
2itzIREEpidermal growth factor receptor2.7.10.10.453
2pvhP19Casein kinase II subunit alpha2.7.11.10.453
3a9wNADNDP-sugar epimerase/0.453
3fhyATPPyridoxal kinase2.7.1.350.453
3kvxFMYMitogen-activated protein kinase 102.7.11.240.453
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.453
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.453
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.453
4wkqIREEpidermal growth factor receptor2.7.10.10.453
5aacVGHALK tyrosine kinase receptor2.7.10.10.453
5dt0SKEAurora kinase A2.7.11.10.453
5e8xSTUTGF-beta receptor type-12.7.11.300.453
1ke7LS3Cyclin-dependent kinase 22.7.11.220.452
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.452
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.452
2w1fL0FAurora kinase A2.7.11.10.452
2yn8STUEphrin type-B receptor 42.7.10.10.452
3dogNNNCyclin-dependent kinase 22.7.11.220.452
3hx4ANPCalmodulin-domain protein kinase 1/0.452
3oqfS51Renin3.4.23.150.452
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.452
4deeADPAurora kinase A2.7.11.10.452
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.452
4g6oE28Mitogen-activated protein kinase 12.7.11.240.452
4grb0XGCasein kinase II subunit alpha2.7.11.10.452
4j97ACPFibroblast growth factor receptor 2/0.452
4jqeANPCasein kinase II subunit alpha2.7.11.10.452
1c70L75Protease/0.451
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1ke6LS2Cyclin-dependent kinase 22.7.11.220.451
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.451
1tvoFRZMitogen-activated protein kinase 12.7.11.240.451
2h96893Mitogen-activated protein kinase 82.7.11.240.451
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.451
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.451
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.451
4gk4L90Ephrin type-A receptor 32.7.10.10.451
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.451
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.451
1oguST8Cyclin-dependent kinase 22.7.11.220.450
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.450
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.450
2wqeADPAurora kinase A2.7.11.10.450
2x9fX9FEphrin type-B receptor 42.7.10.10.450
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.450
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.450
1oirHDYCyclin-dependent kinase 22.7.11.220.449
2g226IGRenin3.4.23.150.449
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.449
2qa2FADPolyketide oxygenase CabE/0.449
2vu3LZECyclin-dependent kinase 22.7.11.220.449
2vx17X8Ephrin type-B receptor 42.7.10.10.449
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.449
3iw4LW4Protein kinase C alpha type2.7.11.130.449
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.449
3qtzX42Cyclin-dependent kinase 22.7.11.220.449
3rkb12ZCyclin-dependent kinase 22.7.11.220.449
3vquO22Dual specificity protein kinase TTK2.7.12.10.449
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.449
3zh8C58Protein kinase C iota type2.7.11.130.449
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.449
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.449
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.449
4jr7GNPCasein kinase II subunit alpha2.7.11.10.449
4nka2K7Fibroblast growth factor receptor 1/0.449
5e8ySTUTGF-beta receptor type-22.7.11.300.449
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
1bxoPP7Penicillopepsin-13.4.23.200.448
1m17AQ4Epidermal growth factor receptor2.7.10.10.448
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.448
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.448
1wvxBD4Death-associated protein kinase 12.7.11.10.448
1xl2189Gag-Pol polyprotein3.4.23.160.448
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.448
2c7xNRBCytochrome P450 monooxygenase PikC/0.448
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.448
2gs7ANPEpidermal growth factor receptor2.7.10.10.448
3nxe2NCProtease/0.448
3oroAGSSerine/threonine protein kinase/0.448
4c4iX20Dual specificity protein kinase TTK2.7.12.10.448
4cy8FDA2-hydroxybiphenyl-3-monooxygenase/0.448
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.448
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.448
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
1hiiC20Gag-Pol polyprotein/0.447
1unlRRCCyclin-dependent-like kinase 52.7.11.10.447
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.447
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.447
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2o2u738Mitogen-activated protein kinase 102.7.11.240.447
2vgoAD5Aurora kinase B-A2.7.11.10.447
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.447
3c4zADPRhodopsin kinase/0.447
3gu6ADPDeath-associated protein kinase 12.7.11.10.447
3nux3NVCyclin-dependent kinase 62.7.11.220.447
4bcnT9NCyclin-dependent kinase 22.7.11.220.447
4bcqTJFCyclin-dependent kinase 22.7.11.220.447
4c4g7RODual specificity protein kinase TTK2.7.12.10.447
4e730NRMitogen-activated protein kinase 82.7.11.240.447
4fkw62KCyclin-dependent kinase 22.7.11.220.447
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.447
4xgxADPFAD:protein FMN transferase/0.447
5drdATPAurora kinase A2.7.11.10.447
5dt4ATPAurora kinase A2.7.11.10.447
1rfvADPPyridoxal kinase2.7.1.350.446
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.446
2balPQAMitogen-activated protein kinase 14/0.446
2fgiPD1Fibroblast growth factor receptor 1/0.446
2vx07X7Ephrin type-B receptor 42.7.10.10.446
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.446
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.446
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.446
3s4qNK0Mitogen-activated protein kinase 14/0.446
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.446
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.446
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.446
3w32W32Epidermal growth factor receptor2.7.10.10.446
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.446
4ansVGHALK tyrosine kinase receptor2.7.10.10.446
4foc0UUALK tyrosine kinase receptor2.7.10.10.446
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.446
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.446
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.446
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.446
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1r78FMDCyclin-dependent kinase 22.7.11.220.445
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.445
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.445
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.445
2j0j4STFocal adhesion kinase 12.7.10.20.445
2pwlACPFibroblast growth factor receptor 2/0.445
3t113T1Gag-Pol polyprotein3.4.23.160.445
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.445
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.445
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1e9hINRCyclin-dependent kinase 22.7.11.220.444
1h1q2A6Cyclin-dependent kinase 22.7.11.220.444
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.444
1xddAAYIntegrin alpha-L/0.444
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.444
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.444
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.444
2of2547Tyrosine-protein kinase Lck2.7.10.20.444
2xikJ60Serine/threonine-protein kinase 252.7.11.10.444
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.444
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.444
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.444
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4fod0UVALK tyrosine kinase receptor2.7.10.10.444
4gmy0X5Tyrosine-protein kinase JAK2/0.444
4lfiGNPCasein kinase II subunit alpha2.7.11.10.444
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.444
5dr9SKEAurora kinase A2.7.11.10.444
1gii1PUCyclin-dependent kinase 22.7.11.220.443
1ig1ANPDeath-associated protein kinase 12.7.11.10.443
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.443
1py5PY1TGF-beta receptor type-12.7.11.300.443
2b52D42Cyclin-dependent kinase 22.7.11.220.443
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.443
2ijmADPFocal adhesion kinase 12.7.10.20.443
2j9mPY8Cyclin-dependent kinase 22.7.11.220.443
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.443
2pzpACPFibroblast growth factor receptor 2/0.443
2x3nFADProbable FAD-dependent monooxygenase/0.443
3aw9NADNAD-dependent epimerase/dehydratase/0.443
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.443
3cktYDPGag-Pol polyprotein3.4.23.160.443
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.443
3h0sB38Acetyl-CoA carboxylase/0.443
3lfqA28Cyclin-dependent kinase 22.7.11.220.443
3nynSGVG protein-coupled receptor kinase 62.7.11.160.443
3ortAGSSerine/threonine protein kinase/0.443
3pe6ZYHMonoglyceride lipase/0.443
4btkDTQTau-tubulin kinase 12.7.11.10.443
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.443
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.443
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.443
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.443
5auuLU2Death-associated protein kinase 12.7.11.10.443
1m2rMNYCasein kinase II subunit alpha2.7.11.10.442
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.442
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.442
2bfyH1NAurora kinase B-A2.7.11.10.442
2c6o4SPCyclin-dependent kinase 22.7.11.220.442
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.442
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.442
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.442
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.442
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.442
3a1nNADNDP-sugar epimerase/0.442
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.442
3eljGS7Mitogen-activated protein kinase 82.7.11.240.442
3k5uPFQAurora kinase A2.7.11.10.442
3lfnA27Cyclin-dependent kinase 22.7.11.220.442
3r9dX6BCyclin-dependent kinase 22.7.11.220.442
3rni21ZCyclin-dependent kinase 22.7.11.220.442
3s0o50ZCyclin-dependent kinase 22.7.11.220.442
3zsi52PMitogen-activated protein kinase 14/0.442
4anqVGHALK tyrosine kinase receptor2.7.10.10.442
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.442
4bcpT3CCyclin-dependent kinase 22.7.11.220.442
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
4cqlNADEstradiol 17-beta-dehydrogenase 81.1.1.620.442
4erwSTUCyclin-dependent kinase 22.7.11.220.442
4hvg19QTyrosine-protein kinase JAK32.7.10.20.442
4mxaBK7Calmodulin-like domain protein kinase isoenzyme gamma, related/0.442
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
1bxqPP8Penicillopepsin-13.4.23.200.441
1pmn984Mitogen-activated protein kinase 102.7.11.240.441
1zz2B11Mitogen-activated protein kinase 14/0.441
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.441
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.441
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.441
2vwx7X4Ephrin type-B receptor 42.7.10.10.441
2wecPP5Penicillopepsin-13.4.23.200.441
2wpa889Cyclin-dependent kinase 22.7.11.220.441
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.441
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.441
3el51UNGag-Pol polyprotein/0.441
3iw7IPKMitogen-activated protein kinase 14/0.441
3t2zFADSulfide-quinone reductase/0.441
3vryB43Tyrosine-protein kinase HCK2.7.10.20.441
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.441
4dgnLU2Casein kinase II subunit alpha2.7.11.10.441
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.441
4h3ySAHtRNA (guanine-N(1)-)-methyltransferase/0.441
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.441
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.441
5dt3ATPAurora kinase A2.7.11.10.441
1dhrNADDihydropteridine reductase1.5.1.340.440
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.440
1ouy094Mitogen-activated protein kinase 14/0.440
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.440
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.440
2p4yC03Peroxisome proliferator-activated receptor gamma/0.440
2pmoHMDProtein kinase 7/0.440
2pvlP55Casein kinase II subunit alpha2.7.11.10.440
2xru400Aurora kinase A2.7.11.10.440
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.440
3fi4FI4Mitogen-activated protein kinase 14/0.440
3flzFLZMitogen-activated protein kinase 14/0.440
3mqe416Prostaglandin G/H synthase 21.14.99.10.440
3ocgOCGMitogen-activated protein kinase 14/0.440
3oev3OEProteasome subunit beta type-53.4.25.10.440
3oev3OEProteasome subunit beta type-63.4.25.10.440
3qa2XNAKetohexokinase/0.440
3r7vZ02Cyclin-dependent kinase 22.7.11.220.440
4anmWULCasein kinase II subunit alpha2.7.11.10.440
4eol1ROCyclin-dependent kinase 22.7.11.220.440
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.440
4nifANPMitogen-activated protein kinase 12.7.11.240.440
4o701QKBromodomain-containing protein 4/0.440
4xumIMNPeroxisome proliferator-activated receptor gamma/0.440
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.440
5e92ANPTGF-beta receptor type-22.7.11.300.440