sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 1.000 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.696 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.677 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.671 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.660 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.626 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.618 | |
| 3r94 | FLR | Aldo-keto reductase family 1 member C3 | / | 0.614 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.614 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.595 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.592 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.585 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.585 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.583 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.581 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.575 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.569 | |
| 3ufy | NPX | Aldo-keto reductase family 1 member C3 | / | 0.562 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.561 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.557 | |
| 3r58 | NPS | Aldo-keto reductase family 1 member C3 | / | 0.549 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.543 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.520 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.491 | |
| 4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.491 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.461 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.460 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.447 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3gsi | THG | Dimethylglycine oxidase | 1.5.3.10 | 0.447 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.445 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4n1f | CZH | Obelin | / | 0.445 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 4hcy | 0YN | Transketolase | / | 0.443 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.442 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.442 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.441 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.441 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.440 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.440 |