scPDB - Distribution of Binding site Similarity values of 4hkn entry / Site 1

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4hkn	LU2	Tankyrase-2	2.4.2.30

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4hkn	LU2	Tankyrase-2	2.4.2.30	1.000
4l31	F08	Tankyrase-2	2.4.2.30	0.642
3kr8	XAV	Tankyrase-2	2.4.2.30	0.639
4kzu	A73	Tankyrase-2	2.4.2.30	0.618
4l0i	1UW	Tankyrase-2	2.4.2.30	0.610
4buf	F36	Tankyrase-2	2.4.2.30	0.609
4l0s	1UZ	Tankyrase-2	2.4.2.30	0.608
4l10	A63	Tankyrase-2	2.4.2.30	0.608
4bu9	08C	Tankyrase-2	2.4.2.30	0.605
4bud	29F	Tankyrase-2	2.4.2.30	0.603
4iue	AJ4	Tankyrase-2	2.4.2.30	0.599
4l0t	1V0	Tankyrase-2	2.4.2.30	0.599
4hlf	15Z	Tankyrase-2	2.4.2.30	0.593
4hkk	AGI	Tankyrase-2	2.4.2.30	0.592
4buu	F38	Tankyrase-2	2.4.2.30	0.586
4l34	1VG	Tankyrase-2	2.4.2.30	0.581
4hlk	431	Tankyrase-2	2.4.2.30	0.580
4l2f	1V3	Tankyrase-2	2.4.2.30	0.576
4bux	F35	Tankyrase-2	2.4.2.30	0.575
4hlg	20B	Tankyrase-2	2.4.2.30	0.575
4bue	JQF	Tankyrase-2	2.4.2.30	0.570
5aku	29F	Tankyrase-2	2.4.2.30	0.570
4kzl	20D	Tankyrase-2	2.4.2.30	0.569
4hl5	15W	Tankyrase-2	2.4.2.30	0.567
4l2k	1V8	Tankyrase-2	2.4.2.30	0.567
4but	31F	Tankyrase-2	2.4.2.30	0.563
4bui	W2E	Tankyrase-2	2.4.2.30	0.560
4hmh	F94	Tankyrase-2	2.4.2.30	0.559
4l33	F70	Tankyrase-2	2.4.2.30	0.559
4j22	AJ7	Tankyrase-2	2.4.2.30	0.558
4l32	1VF	Tankyrase-2	2.4.2.30	0.556
4l2g	1V4	Tankyrase-2	2.4.2.30	0.551
4l0v	1V1	Tankyrase-2	2.4.2.30	0.546
4avw	G18	Tankyrase-2	2.4.2.30	0.542
4hlh	20D	Tankyrase-2	2.4.2.30	0.539
4bus	32F	Tankyrase-2	2.4.2.30	0.529
4hlm	16S	Tankyrase-2	2.4.2.30	0.525
4j21	AJ6	Tankyrase-2	2.4.2.30	0.524
3p0p	NNF	Tankyrase-2	2.4.2.30	0.511
4hki	FLN	Tankyrase-2	2.4.2.30	0.500
4pnr	G18	Tankyrase-2	2.4.2.30	0.494
4buw	F33	Tankyrase-2	2.4.2.30	0.493
4tkg	09L	Tankyrase-2	2.4.2.30	0.489
4bjb	P34	Tankyrase-2	2.4.2.30	0.483
4bs4	A64	Tankyrase-2	2.4.2.30	0.477
4msk	2C8	Tankyrase-1	2.4.2.30	0.472
4l09	1UR	Tankyrase-2	2.4.2.30	0.459
4buv	16I	Tankyrase-2	2.4.2.30	0.445
4j3l	AJ5	Tankyrase-2	2.4.2.30	0.443