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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4h4vFADBiphenyl dioxygenase ferredoxin reductase subunit

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4h4vFADBiphenyl dioxygenase ferredoxin reductase subunit/1.000
2gqwFADFerredoxin reductase/0.749
2gr3FADFerredoxin reductase/0.675
4h4sFADBiphenyl dioxygenase ferredoxin reductase subunit/0.667
4h4pFADBiphenyl dioxygenase ferredoxin reductase subunit/0.651
4h50FADBiphenyl dioxygenase ferredoxin reductase subunit/0.583
4h4tFADBiphenyl dioxygenase ferredoxin reductase subunit/0.560
4h4rFADBiphenyl dioxygenase ferredoxin reductase subunit/0.550
4h4yFADBiphenyl dioxygenase ferredoxin reductase subunit/0.522
1f3pFADFerredoxin reductase/0.514
3gd3FADApoptosis-inducing factor 1, mitochondrial1.1.10.509
4h4zFADBiphenyl dioxygenase ferredoxin reductase subunit/0.489
4emjFADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component1.18.1.30.480
1gv4FADApoptosis-inducing factor 1, mitochondrial1.1.10.479
5fs6FADApoptosis-inducing factor 1, mitochondrial1.1.10.479
3ef6FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component1.18.1.30.477
4h4wFADBiphenyl dioxygenase ferredoxin reductase subunit/0.467
2yvjFADFerredoxin reductase/0.460
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.457
4bv6FADApoptosis-inducing factor 1, mitochondrial1.1.10.449
4liiFADApoptosis-inducing factor 1, mitochondrial1.1.10.449
2gr0FADFerredoxin reductase/0.447
4burFADApoptosis-inducing factor 1, mitochondrial1.1.10.443