sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4h3y | SAH | tRNA (guanine-N(1)-)-methyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4h3y | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 1.000 | |
| 4h3z | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.570 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.461 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.460 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.458 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.456 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.454 | |
| 3s3r | 0IW | Cathepsin B-like peptidase (C01 family) | / | 0.452 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.450 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.450 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.446 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.443 | |
| 4irn | FAD | AnaB | / | 0.443 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3cge | NDP | Coenzyme A disulfide reductase | / | 0.441 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.441 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.440 |