Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4h0n | SAH | Dnmt2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4h0n | SAH | Dnmt2 | / | 1.000 | |
| 3qv2 | SAH | 5-cytosine DNA methyltransferase | / | 0.471 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.454 | |
| 3pt9 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.451 | |
| 8mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.449 | |
| 4wxx | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.442 | |
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.441 | |
| 2zcj | SAH | Modification methylase HhaI | 2.1.1.37 | 0.440 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 5mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.440 |