sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 1.000 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.507 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.506 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.505 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.496 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.488 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.483 | |
| 4dvg | GSP | Rho family GTPase | / | 0.482 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.477 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.473 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.465 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.464 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.463 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.462 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.460 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.457 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.450 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.449 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.449 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.442 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4mit | GTP | Rho-related protein racC | / | 0.442 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.441 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.441 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.441 | |
| 3c16 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.440 |