Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.301.000
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.769
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.766
3c49KU8Poly [ADP-ribose] polymerase 32.4.2.300.668
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.520
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.519
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.517
1uk0FRMPoly [ADP-ribose] polymerase 12.4.2.300.500
3c4hDRLPoly [ADP-ribose] polymerase 32.4.2.300.484
4r5wXAVPoly [ADP-ribose] polymerase 12.4.2.300.481
1uk1FRQPoly [ADP-ribose] polymerase 12.4.2.300.475
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.472
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.462
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.452
4l6s1WQPoly [ADP-ribose] polymerase 12.4.2.300.447