sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 1.000 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.655 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.601 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.567 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.554 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.540 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.538 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.536 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.530 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.529 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.524 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.516 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.514 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.503 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.498 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.498 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.497 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.491 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.491 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.475 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.473 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.470 | |
| 2bac | FAD | Putative aminooxidase | / | 0.470 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.467 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.463 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.463 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.460 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.458 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.457 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.457 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.456 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.456 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.455 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.452 | |
| 5dp2 | NAP | CurF | / | 0.452 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.450 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.446 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.444 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.440 |