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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4gtm7TMProtein farnesyltransferase subunit beta2.5.1.58

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4gtm7TMProtein farnesyltransferase subunit beta2.5.1.581.000
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.642
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.629
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.616
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.615
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.608
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.605
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.602
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.594
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.592
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.591
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.589
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.586
1s63778Protein farnesyltransferase subunit beta2.5.1.580.579
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.575
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.573
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.572
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.562
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.562
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.557
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.553
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.527
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.514
4gto7TOProtein farnesyltransferase subunit beta2.5.1.580.508
1n4qLYS_CYS_VAL_ILE_LEUGeranylgeranyl transferase type-1 subunit beta2.5.1.590.504
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.503
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.499
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.484
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.481
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.479
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.474
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.470
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.464
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.464
3sfy3FYUncharacterized protein/0.461
3q7fED2Uncharacterized protein/0.445