Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4gtlFADFlavin-dependent thymidylate synthase2.1.1.148

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4gtlFADFlavin-dependent thymidylate synthase2.1.1.1481.000
1o29FADFlavin-dependent thymidylate synthase2.1.1.1480.496
1kq4FADFlavin-dependent thymidylate synthase2.1.1.1480.486
3n0cFADFlavin-dependent thymidylate synthase2.1.1.1480.483
3n0bFADFlavin-dependent thymidylate synthase2.1.1.1480.480
3g4aFADFlavin-dependent thymidylate synthase2.1.1.1480.469
5iosFADFlavin-dependent thymidylate synthase2.1.1.1480.459