sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4gp6 | ADP | Metallophosphoesterase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4gp6 | ADP | Metallophosphoesterase | / | 1.000 | |
| 4jsy | GTP | Metallophosphoesterase | / | 0.586 | |
| 4qm6 | GTP | Metallophosphoesterase | / | 0.580 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.485 | |
| 3tqc | ADP | Pantothenate kinase | / | 0.483 | |
| 1rj9 | GCP | Signal recognition particle receptor FtsY | / | 0.469 | |
| 3w8r | ACP | Uridine kinase | / | 0.465 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.459 | |
| 3pfi | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.459 | |
| 1w5t | ADP | ORC1-type DNA replication protein 2 | / | 0.456 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.455 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.455 | |
| 4k10 | NI9 | Farnesyl pyrophosphate synthase | / | 0.453 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.450 | |
| 4y8v | ADP | Acyl-CoA synthetase (NDP forming) | / | 0.449 | |
| 1sb8 | UD2 | WbpP | / | 0.448 | |
| 2w02 | ATP | AcsD | / | 0.448 | |
| 3jsz | UPG | Uncharacterized protein | / | 0.445 | |
| 4mb2 | ATP | Uncharacterized protein | / | 0.443 | |
| 3h5n | ATP | MccB protein | / | 0.442 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 |