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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.29

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.291.000
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.645
4gkt0O1Queuine tRNA-ribosyltransferase2.4.2.290.614
3sm0AEKQueuine tRNA-ribosyltransferase2.4.2.290.602
3ge7AFQQueuine tRNA-ribosyltransferase2.4.2.290.595
4gg90WWQueuine tRNA-ribosyltransferase2.4.2.290.594
4fps0UXQueuine tRNA-ribosyltransferase2.4.2.290.571
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.564
1q63AIQQueuine tRNA-ribosyltransferase2.4.2.290.542
4fr10V2Queuine tRNA-ribosyltransferase2.4.2.290.529
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.522
1y5vNE8Queuine tRNA-ribosyltransferase2.4.2.290.509
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.509
1efzPRFQueuine tRNA-ribosyltransferase2.4.2.290.500
2z1wBDIQueuine tRNA-ribosyltransferase2.4.2.290.500
4fsa0V3Queuine tRNA-ribosyltransferase2.4.2.290.493
4giy0WYQueuine tRNA-ribosyltransferase2.4.2.290.493
1f3eDPZQueuine tRNA-ribosyltransferase2.4.2.290.491
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.486
4hqvQEIQueuine tRNA-ribosyltransferase2.4.2.290.484
1q66KMBQueuine tRNA-ribosyltransferase2.4.2.290.475
1y5wNEZQueuine tRNA-ribosyltransferase2.4.2.290.473
4hvxQEIQueuine tRNA-ribosyltransferase2.4.2.290.470
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.468
2z1xPRFQueuine tRNA-ribosyltransferase2.4.2.290.465
4q8pCKRQueuine tRNA-ribosyltransferase2.4.2.290.464
1q65BHBQueuine tRNA-ribosyltransferase2.4.2.290.456
3eigMTXDihydrofolate reductase1.5.1.30.456
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.455
1n71COAAac(6')-Ii protein/0.452
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.451
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.448
3lfeZ84Mitogen-activated protein kinase 14/0.447
1pxgPRFQueuine tRNA-ribosyltransferase2.4.2.290.444
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.444
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.444
4h9753SDihydrofolate reductase1.5.1.30.444
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.443
3bi6396Wee1-like protein kinase2.7.10.20.442
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.442
4hshQEIQueuine tRNA-ribosyltransferase2.4.2.290.442
4u0oMTALipoyl synthase 2/0.441
3gcq1BUMitogen-activated protein kinase 14/0.440
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.440