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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4gd40WSLysine-specific demethylase 4A1.14.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4gd40WSLysine-specific demethylase 4A1.14.111.000
3pdqKC6Lysine-specific demethylase 4A1.14.110.739
4bis8HQLysine-specific demethylase 4A1.14.110.600
2wwjY28Lysine-specific demethylase 4A/0.598
2vd7PD2Lysine-specific demethylase 4A1.14.110.594
4lxlPD2Lysine-specific demethylase 4B1.14.110.582
3rvhHQ2Lysine-specific demethylase 4A1.14.110.575
4d6qPD2Lysine-specific demethylase 4D1.14.110.574
4bfzZVZPantothenate kinase2.7.1.330.477
1r58AO5Methionine aminopeptidase 2/0.459
2qimZEAClass 10 plant pathogenesis-related protein/0.459
2ea2F77Methionine aminopeptidase 2/0.456
2g1s4IGRenin3.4.23.150.455
2g1r3IGRenin3.4.23.150.453
2gv8NDPThiol-specific monooxygenase1.14.130.453
1rneC60Renin3.4.23.150.452
2g226IGRenin3.4.23.150.452
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.451
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.450
2ea4F79Methionine aminopeptidase 2/0.449
4bfwZVWPantothenate kinase2.7.1.330.448
3enkUPGUDP-glucose 4-epimerase/0.442
2ga2A19Methionine aminopeptidase 2/0.441
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441