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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4gcxPRFQueuine tRNA-ribosyltransferase2.4.2.29

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4gcxPRFQueuine tRNA-ribosyltransferase2.4.2.291.000
4hqvQEIQueuine tRNA-ribosyltransferase2.4.2.290.800
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.791
4hvxQEIQueuine tRNA-ribosyltransferase2.4.2.290.740
3bllBPQQueuine tRNA-ribosyltransferase2.4.2.290.708
4hshQEIQueuine tRNA-ribosyltransferase2.4.2.290.687
1f3eDPZQueuine tRNA-ribosyltransferase2.4.2.290.652
4h7zGUNQueuine tRNA-ribosyltransferase2.4.2.290.623
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.617
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.601
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.290.601
3bloQEIQueuine tRNA-ribosyltransferase2.4.2.290.588
1efzPRFQueuine tRNA-ribosyltransferase2.4.2.290.580
4fps0UXQueuine tRNA-ribosyltransferase2.4.2.290.575
4gg90WWQueuine tRNA-ribosyltransferase2.4.2.290.565
2bbf344Queuine tRNA-ribosyltransferase2.4.2.290.563
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.554
2z1wBDIQueuine tRNA-ribosyltransferase2.4.2.290.553
3bldPRFQueuine tRNA-ribosyltransferase2.4.2.290.549
2z1xPRFQueuine tRNA-ribosyltransferase2.4.2.290.543
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.541
1pxgPRFQueuine tRNA-ribosyltransferase2.4.2.290.537
3ge7AFQQueuine tRNA-ribosyltransferase2.4.2.290.535
3sm0AEKQueuine tRNA-ribosyltransferase2.4.2.290.529
4fsa0V3Queuine tRNA-ribosyltransferase2.4.2.290.529
1q63AIQQueuine tRNA-ribosyltransferase2.4.2.290.513
4giy0WYQueuine tRNA-ribosyltransferase2.4.2.290.508
1x8b824Wee1-like protein kinase2.7.10.20.503
2qzrS79Queuine tRNA-ribosyltransferase2.4.2.290.497
1p0ePRFQueuine tRNA-ribosyltransferase2.4.2.290.496
3gc52MQQueuine tRNA-ribosyltransferase2.4.2.290.492
1lbbKAIGlutamate receptor 2/0.491
4gki0JNAminoglycoside 3'-phosphotransferase AphA1-IAB/0.491
3hv3R49Mitogen-activated protein kinase 14/0.490
3s7a684Dihydrofolate reductase1.5.1.30.488
3biz61EWee1-like protein kinase2.7.10.20.485
4jeyPLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.485
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.483
1r5yDQUQueuine tRNA-ribosyltransferase2.4.2.290.482
4ndnSAMS-adenosylmethionine synthase isoform type-22.5.1.60.482
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.480
4fevPP1Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.480
1n3sGTPGTP cyclohydrolase 13.5.4.160.479
4dju0KKBeta-secretase 13.4.23.460.478
2z2w770Wee1-like protein kinase2.7.10.20.477
4iilRBFMembrane lipoprotein TpN38(b)/0.477
4jlm1NNDeoxycytidine kinase2.7.1.740.477
4ts7ADPPurine phosphoribosyltransferase (GpT-1)/0.476
5dozNDPJamJ/0.476
1synF89Thymidylate synthase/0.475
1zy5ANPeIF-2-alpha kinase GCN2/0.475
4lutDCSAlanine racemase/0.475
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.474
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.474
4h1e10JBeta-secretase 13.4.23.460.474
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.473
1pd8CO4Dihydrofolate reductase1.5.1.30.472
2bakAQZMitogen-activated protein kinase 14/0.472
4a9yAQZMitogen-activated protein kinase 14/0.472
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
1kruIPTGalactoside O-acetyltransferase2.3.1.180.471
2io6330Wee1-like protein kinase2.7.10.20.471
3zkyWT4Isopenicillin N synthase1.21.3.10.471
4bfuZVUPantothenate kinase2.7.1.330.471
1gky5GPGuanylate kinase2.7.4.80.470
1mrqSTRAldo-keto reductase family 1 member C1/0.470
2clfF6FTryptophan synthase alpha chain/0.470
4iaq2GM5-hydroxytryptamine receptor 1B/0.470
4q8pCKRQueuine tRNA-ribosyltransferase2.4.2.290.470
4u0k744Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.470
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.469
2pl0STITyrosine-protein kinase Lck2.7.10.20.469
1efaNPFLactose operon repressor/0.468
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.468
3iktNADRedox-sensing transcriptional repressor Rex/0.468
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.468
3x04GNPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.468
4f3gKAIGlutamate receptor 3/0.468
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.468
1q65BHBQueuine tRNA-ribosyltransferase2.4.2.290.467
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.467
3fr28CAFatty acid-binding protein, adipocyte/0.467
4a4l939Serine/threonine-protein kinase PLK12.7.11.210.467
4bgbADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases/0.467
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.467
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
1fw0KAIGlutamate receptor 2/0.466
2ed3SAHDiphthine synthase/0.466
3cqeP91Wee1-like protein kinase2.7.10.20.466
1yhjR6CPyridoxal kinase2.7.1.350.465
1diaL24C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.464
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.464
2xejOKDGlutamate carboxypeptidase 23.4.17.210.464
2yac937Serine/threonine-protein kinase PLK12.7.11.210.464
3nxyD2HDihydrofolate reductase1.5.1.30.464
3znrNU9Histone deacetylase 73.5.1.980.464
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.464
4l2zS7MS-adenosylmethionine synthase/0.464
1krv147Galactoside O-acetyltransferase2.3.1.180.463
2bfmTOPPteridine reductase 11.5.1.330.463
3bi6396Wee1-like protein kinase2.7.10.20.463
3zdfNADGlyceraldehyde-3-phosphate dehydrogenase/0.463
4bj9UHBTankyrase-22.4.2.300.463
1dr4HBIDihydrofolate reductase1.5.1.30.462
1el4CTZObelin/0.462
2in6839Wee1-like protein kinase2.7.10.20.462
2pupADPMethylthioribose kinase2.7.1.1000.462
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.462
4iyg1HUStrictosidine synthase4.3.3.20.462
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.461
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
1s7gNADNAD-dependent protein deacylase 2/0.461
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.461
2x06NADL-sulfolactate dehydrogenase/0.460
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.460
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.460
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.460
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.460
5k2cZMAAdenosine receptor A2a/0.460
2clmF6FTryptophan synthase alpha chain/0.459
2x9vTMQPteridine reductase/0.459
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3h3qH13Collagen type IV alpha-3-binding protein/0.459
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.459
3owxXRARibosyldihydronicotinamide dehydrogenase [quinone]/0.459
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4b6l9ZPSerine/threonine-protein kinase PLK32.7.11.210.459
3emlZMAAdenosine receptor A2a/0.459
1rxjBNIStreptavidin/0.458
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.458
1ygjRMCPyridoxal kinase2.7.1.350.458
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2bn4FMNNADPH--cytochrome P450 reductase/0.458
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.458
2jf6S55Strictosidine-O-beta-D-glucosidase3.2.1.1050.458
2ydoADNAdenosine receptor A2a/0.458
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3fr5I4AFatty acid-binding protein, adipocyte/0.458
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.458
3znsNU7Histone deacetylase 73.5.1.980.458
4o6fSAHN-lysine methyltransferase SMYD2/0.458
4tjy3GNTankyrase-22.4.2.300.458
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.457
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.457
2cbjOANO-GlcNAcase NagJ/0.457
2xvfFADPutative flavin-containing monooxygenase/0.457
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.457
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.457
3ojiPYVAbscisic acid receptor PYL3/0.457
3q3cNADNAD-dependent L-serine dehydrogenase/0.457
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.457
4bftZVTPantothenate kinase2.7.1.330.457
4bubADPUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase/0.457
4px9ADPATP-dependent RNA helicase DDX3X3.6.4.130.457
4z9rNADOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.457
5dp2NAPCurF/0.457
4mqt2CUMuscarinic acetylcholine receptor M2/0.457
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1qv1CZHObelin/0.456
1xddAAYIntegrin alpha-L/0.456
2ejzSAHDiphthine synthase/0.456
3aw9GDUNAD-dependent epimerase/dehydratase/0.456
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.456
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.456
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
1p33MTXPteridine reductase 11.5.1.330.455
2j415GPGuanylate kinase/0.455
3eon341Glutaryl-CoA dehydrogenase/0.455
3mteSAM16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.455
3v0o4GWHisto-blood group ABO system transferase/0.455
4iarERM5-hydroxytryptamine receptor 1B/0.455
4klnAGSTransitional endoplasmic reticulum ATPase3.6.4.60.455
4y1bNAPAntE/0.455
1ne4RP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.454
1yw8A75Methionine aminopeptidase 2/0.454
2w6zL21Biotin carboxylase6.3.4.140.454
3axsSFGtRNA (guanine(26)-N(2)/guanine(27)-N(2))-dimethyltransferase/0.454
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.454
3dgeADPSensor histidine kinase/0.454
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3fhxPLPPyridoxal kinase2.7.1.350.454
3qfrFMNNADPH--cytochrome P450 reductase/0.454
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.454
5j60FADThioredoxin reductase/0.454
3rfmCFFAdenosine receptor A2a/0.454
1wm1PTBProline iminopeptidase3.4.11.50.453
2cjfRP43-dehydroquinate dehydratase4.2.1.100.453
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.453
2potGUNQueuine tRNA-ribosyltransferase2.4.2.290.453
2rehFADNitroalkane oxidase1.7.3.10.453
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.453
3gieACPSensor histidine kinase DesK2.7.13.30.453
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.453
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4s1iPLPPyridoxal kinase, putative/0.453
4u7wNDPMxaA/0.453
5k2aZMAAdenosine receptor A2a/0.453
5iua6DXAdenosine receptor A2a/0.453
2vcmM11Isopenicillin N synthase1.21.3.10.452
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3arvSAUChitinase A/0.452
3e5aVX6Aurora kinase A2.7.11.10.452
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.452
3vt7VDXVitamin D3 receptor/0.452
3vv8B02Beta-secretase 13.4.23.460.452
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.452
4bdrKAIGlutamate receptor ionotropic, kainate 2/0.452
4ea2RWZDehydrosqualene synthase/0.452
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4jpe1M7Beta-secretase 13.4.23.460.452
1ye6NAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.451
2wn6NDPADP-ribosyltransferase enzymatic component/0.451
2xtbKRMAdenosine kinase, putative/0.451
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.451
3ihgVAKAklavinone 12-hydroxylase RdmE/0.451
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3lpfZ77Beta-glucuronidase3.2.1.310.451
3nxtD2EDihydrofolate reductase1.5.1.30.451
4e0u0MVCyclic dipeptide N-prenyltransferase/0.451
4ixfIXFDihydrofolate reductase1.5.1.30.451
2yczI32Beta-1 adrenergic receptor/0.451
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.450
2ph5NADHomospermidine synthase/0.450
2vd0D27Hematopoietic prostaglandin D synthase/0.450
2wgs1AZGlutamine synthetase6.3.1.20.450
3b05FNRIsopentenyl-diphosphate delta-isomerase/0.450
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.450
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.450
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.450
4djx0KQBeta-secretase 13.4.23.460.450
4eoi1ROCyclin-dependent kinase 22.7.11.220.450
4eol1ROCyclin-dependent kinase 22.7.11.220.450
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.450
1lb9DNQGlutamate receptor 2/0.449
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.449
2bn4FADNADPH--cytochrome P450 reductase/0.449
2xeiARKGlutamate carboxypeptidase 23.4.17.210.449
3frdDHFDihydrofolate reductase1.5.1.30.449
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
3pdqKC6Lysine-specific demethylase 4A1.14.110.449
4b78KGGBeta-secretase 13.4.23.460.449
2mokFMNFlavodoxin 1/0.448
2qcxPF1Aminopyrimidine aminohydrolase/0.448
2vt4P32Beta-1 adrenergic receptor/0.448
2w3aTOPDihydrofolate reductase1.5.1.30.448
3cr0809Wee1-like protein kinase2.7.10.20.448
3hk1B64Fatty acid-binding protein, adipocyte/0.448
3rsv3RSBeta-secretase 13.4.23.460.448
3vilSA0Beta-glucosidase/0.448
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.448
4azy7F3Beta-secretase 13.4.23.460.448
4bfwZVWPantothenate kinase2.7.1.330.448
4bwaN0BPyrrolysine--tRNA ligase/0.448
4ddrMMVDihydrofolate reductase1.5.1.30.448
5iu86DZAdenosine receptor A2a/0.448
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.447
1g7vPAI2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.447
1og1TADT-cell ecto-ADP-ribosyltransferase 2/0.447
1v7aFRCAdenosine deaminase3.5.4.40.447
2pufGUNHTH-type transcriptional repressor PurR/0.447
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.447
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.447
4gusFADLysine-specific histone demethylase 1B10.447
4h3f10OBeta-secretase 13.4.23.460.447
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.447
4stdBFSScytalone dehydratase4.2.1.940.447
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.447
5fsxADPUncharacterized protein/0.447
1bucFADAcyl-CoA dehydrogenase, short-chain specific1.3.8.10.446
1ix1BB2Peptide deformylase/0.446
2a9z26AAdenosine kinase2.7.1.200.446
2fjeFADAdenylylsulfate reductase, subunit A (AprA)/0.446
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.446
3occDIHPurine nucleoside phosphorylase DeoD-type/0.446
3q44D50M1 family aminopeptidase3.4.110.446
3rl45GPMetallophosphoesterase MPPED23.10.446
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
3x065GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.446
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4cdmFO1Deoxyribodipyrimidine photolyase/0.446
4da8BG2Purine nucleoside phosphorylase DeoD-type2.4.2.10.446
4fal0T0Aldo-keto reductase family 1 member C3/0.446
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.446
4plpNADHomospermidine synthase2.5.1.440.446
4u0mGTPCyclic GMP-AMP synthase/0.446
3uzaT4GAdenosine receptor A2a/0.446
1qv0CZHObelin/0.445
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.445
1yw7A41Methionine aminopeptidase 2/0.445
2icyUPGUTP--glucose-1-phosphate uridylyltransferase 22.7.7.90.445
2nsd4PIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2zb8IMNProstaglandin reductase 21.3.1.480.445
3dfrMTXDihydrofolate reductase1.5.1.30.445
3fhxPXLPyridoxal kinase2.7.1.350.445
3r7mSUZAldo-keto reductase family 1 member C3/0.445
3w3zGTPGTP-binding nuclear protein Ran/0.445
3zknWZVBeta-secretase 23.4.23.450.445
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.445
4frkDWDBeta-secretase 13.4.23.460.445
4jbtASDCytochrome P450 monooxygenase/0.445
4kbn25UDihydrofolate reductase1.5.1.30.445
4qzuRTLRetinol-binding protein 2/0.445
1mlzPLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.444
1sg0STLRibosyldihydronicotinamide dehydrogenase [quinone]/0.444
1u1cBAUUridine phosphorylase2.4.2.30.444
1ve3SAMUncharacterized protein/0.444
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2f3815MAldo-keto reductase family 1 member C3/0.444
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.444
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.444
2puiADPMethylthioribose kinase2.7.1.1000.444
3gb4D3MDdmC/0.444
3sqyQ11Dihydrofolate reductase1.5.1.30.444
3udq09EBeta-secretase 13.4.23.460.444
3v2bAR6Poly [ADP-ribose] polymerase 152.4.2.300.444
4b7754MBeta-secretase 13.4.23.460.444
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.444
4xrgNADHomospermidine synthase2.5.1.440.444
1a9cGTPGTP cyclohydrolase 13.5.4.160.443
1bk0ACVIsopenicillin N synthase1.21.3.10.443
1qiqACCIsopenicillin N synthase1.21.3.10.443
1wc0APCAdenylate cyclase/0.443
1xzqFONtRNA modification GTPase MnmE3.6.50.443
1z6tADPApoptotic protease-activating factor 1/0.443
2a4xBLMMitomycin-binding protein/0.443
2wqoVGKSerine/threonine-protein kinase Nek22.7.11.10.443
2z7gEH9Adenosine deaminase3.5.4.40.443
3co93MSGenome polyprotein2.7.7.480.443
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.443
3lfzADPUncharacterized protein MJ1225/0.443
3n87N873-dehydroquinate dehydratase4.2.1.100.443
3nxrD2DDihydrofolate reductase1.5.1.30.443
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.443
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
3up3XCAaceDAF-12/0.443
3x025GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.443
4bfxZVXPantothenate kinase2.7.1.330.443
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4dxlC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.443
4g95OAGDihydrofolate reductase1.5.1.30.443
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.443
4tx9AMZPhosphoribosyl isomerase A/0.443
4xba5GPAprataxin-like protein30.443
5k2bZMAAdenosine receptor A2a/0.443
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1n5vNOMActVA 6 protein/0.442
1pd9CO4Dihydrofolate reductase1.5.1.30.442
1t0iFMNNAD(P)H-dependent FMN reductase LOT6/0.442
1typNAPTrypanothione reductase1.8.1.120.442
2przOMPOrotate phosphoribosyltransferase 12.4.2.100.442
3l5dBDVBeta-secretase 13.4.23.460.442
3rvhHQ2Lysine-specific demethylase 4A1.14.110.442
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.442
3vaqADNPutative adenosine kinase/0.442
3vi5M4MHematopoietic prostaglandin D synthase/0.442
3zloX8UBcl-2-like protein 1/0.442
3zoiM2WIsopenicillin N synthase1.21.3.10.442
4b0532DBeta-secretase 13.4.23.460.442
4bb3KKAIsopenicillin N synthase1.21.3.10.442
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.442
4iae1DXAlr2278 protein/0.442
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.442
4mv1ADPBiotin carboxylase6.3.4.140.442
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.442
1hfqMOTDihydrofolate reductase1.5.1.30.441
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1jdzFMBPurine nucleoside phosphorylase/0.441
1towCRZFatty acid-binding protein, adipocyte/0.441
1u1gBBBUridine phosphorylase2.4.2.30.441
1uzwCDHIsopenicillin N synthase1.21.3.10.441
1zdwFLVPrenyltransferase/0.441
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.441
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.441
2nnqT4BFatty acid-binding protein, adipocyte/0.441
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.441
2vroNDP3,4-dehydroadipyl-CoA semialdehyde dehydrogenase/0.441
2x23TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
3anmSYD1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.441
3fr4F8AFatty acid-binding protein, adipocyte/0.441
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.441
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.441
4cnkFADL-amino acid oxidase/0.441
4dbs0HVAldo-keto reductase family 1 member C3/0.441
4eb7PLPCysteine desulfurase IscS 2/0.441
4kd79DRDihydrofolate reductase1.5.1.30.441
5c1gGDUHisto-blood group ABO system transferase/0.441
1ex75GPGuanylate kinase2.7.4.80.440
1obnASVIsopenicillin N synthase1.21.3.10.440
1sq5ADPPantothenate kinase2.7.1.330.440
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2a3bCFFEndochitinase B13.2.1.140.440
2bfaCB3Pteridine reductase 11.5.1.330.440
2cleF6FTryptophan synthase alpha chain/0.440
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.440
2j9lATPH(+)/Cl(-) exchange transporter 5/0.440
2w3vTOPDihydrofolate reductase/0.440
2y53NAP3,4-dehydroadipyl-CoA semialdehyde dehydrogenase/0.440
3d5wADPSerine/threonine-protein kinase PLK/0.440
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3e9sTTTReplicase polyprotein 1ab3.4.220.440
3hy4N5G5-formyltetrahydrofolate cyclo-ligase6.3.3.20.440
3njoPYVAbscisic acid receptor PYR1/0.440
3tptADPSerine/threonine-protein kinase toxin HipA/0.440
4d9eLCSD-cysteine desulfhydrase/0.440
4edz0O5Hematopoietic prostaglandin D synthase/0.440
4gt8ADPSensor protein VraS2.7.13.30.440
4kak06UDihydrofolate reductase1.5.1.30.440
2ycxP32Beta-1 adrenergic receptor/0.440
5g53NECAdenosine receptor A2a/0.440