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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ga8SBIAldo-keto reductase family 1 member B101.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4ga8SBIAldo-keto reductase family 1 member B101.1.11.000
2inzOHPAldose reductase1.1.1.210.617
2pdyFIDAldose reductase1.1.1.210.607
3ghsLDTAldose reductase1.1.1.210.593
2pdwFIDAldose reductase1.1.1.210.586
2fz9ZSTAldose reductase1.1.1.210.581
3g5eQ74Aldose reductase1.1.1.210.580
1z3n3NAAldose reductase1.1.1.210.579
2i16LDTAldose reductase1.1.1.210.578
2f2kTGGAldose reductase1.1.1.210.572
2iqdLPAAldose reductase1.1.1.210.572
4wevSUZAldo-keto reductase family 1 member B101.1.10.572
2pdxZSTAldose reductase1.1.1.210.571
3mb9ZSTAldose reductase1.1.1.210.569
2fzdTOLAldose reductase1.1.1.210.566
2qxwLDTAldose reductase1.1.1.210.565
3s3gTLTAldose reductase1.1.1.210.565
3ghrLDTAldose reductase1.1.1.210.564
1ieiZESAldose reductase1.1.1.210.561
1us0LDTAldose reductase1.1.1.210.560
2hvoZSTAldose reductase1.1.1.210.558
5liu388Aldo-keto reductase family 1 member B101.1.10.558
3u2cSUZAldose reductase1.1.1.210.557
4gabFIDAldo-keto reductase family 1 member B101.1.10.557
4gca2X9Aldose reductase1.1.1.210.555
1ah0SBIAldose reductase1.1.1.210.551
1pwlBFIAldose reductase1.1.1.210.551
2iki388Aldose reductase1.1.1.210.551
2dv0ZSTAldose reductase1.1.1.210.546
2hv5ZSTAldose reductase1.1.1.210.546
3m4h388Aldose reductase1.1.1.210.540
2ikj393Aldose reductase1.1.1.210.539
3m0iZSTAldose reductase1.1.1.210.539
1ekoI84Aldose reductase1.1.1.210.538
3lboLDTAldose reductase1.1.1.210.537
2is72CLAldose reductase1.1.1.210.533
2pdu393Aldose reductase1.1.1.210.532
3ld5LDTAldose reductase1.1.1.210.532
3ghuLDTAldose reductase1.1.1.210.527
2i17LDTAldose reductase1.1.1.210.526
1el3I84Aldose reductase1.1.1.210.525
3lz5LDTAldose reductase1.1.1.210.524
1t40ID5Aldose reductase1.1.1.210.522
3lenZSTAldose reductase1.1.1.210.521
3m64393Aldose reductase1.1.1.210.519
3mc5393Aldose reductase1.1.1.210.519
2pdn47DAldose reductase1.1.1.210.518
2agtFIDAldose reductase1.1.1.210.514
2duzZSTAldose reductase1.1.1.210.513
2fz8ZSTAldose reductase1.1.1.210.513
1h22E10Acetylcholinesterase3.1.1.70.512
1isgAGSADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.512
2pdp393Aldose reductase1.1.1.210.512
3t423T4Aldose reductase1.1.1.210.511
4wljIK2Kynurenine--oxoglutarate transaminase 12.6.1.70.509
3v35NTIAldose reductase1.1.1.210.508
1frbZSTAldose reductase-related protein 2/0.506
2pdmZSTAldose reductase1.1.1.210.506
2w6cBM4Acetylcholinesterase3.1.1.70.506
3lqlLDTAldose reductase1.1.1.210.506
4yu153NAldose reductase1.1.1.210.506
1q84TZ4Acetylcholinesterase3.1.1.70.505
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.505
5d6lCAUBeta-2 adrenergic receptor/0.505
2j3qTFLAcetylcholinesterase3.1.1.70.504
2pdc393Aldose reductase1.1.1.210.504
3cv7C2UAlcohol dehydrogenase [NADP(+)]1.1.1.20.504
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.503
2duxZSTAldose reductase1.1.1.210.503
2pdkSBIAldose reductase1.1.1.210.503
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.503
2cekN8TAcetylcholinesterase3.1.1.70.502
2evmFC2Methionine aminopeptidase/0.502
1t41ID5Aldose reductase1.1.1.210.501
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.501
3pkdY10Methionine aminopeptidase 2/0.498
4fam0SZAldo-keto reductase family 1 member C3/0.497
2ikhLITAldose reductase1.1.1.210.495
2pdj393Aldose reductase1.1.1.210.495
2gyuHI6Acetylcholinesterase3.1.1.70.494
1e1fPSG4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.493
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.493
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.493
4dbs0HVAldo-keto reductase family 1 member C3/0.493
4ey7E20Acetylcholinesterase3.1.1.70.493
4m0f1YKAcetylcholinesterase3.1.1.70.493
2pdq47DAldose reductase1.1.1.210.492
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.492
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.492
1d3dBZTProthrombin3.4.21.50.491
1u65CP0Acetylcholinesterase3.1.1.70.491
1z8962PAldose reductase1.1.1.210.491
2fzbTOLAldose reductase1.1.1.210.491
2pd5ZSTAldose reductase1.1.1.210.491
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.489
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.489
2nvcITAAldose reductase1.1.1.210.489
2pdbZSTAldose reductase1.1.1.210.489
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.489
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.489
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.489
4ey6GNTAcetylcholinesterase3.1.1.70.489
1w4lGL8Acetylcholinesterase3.1.1.70.488
2pb1NFGGlucan 1,3-beta-glucosidase/0.488
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.488
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.486
2pdiZSTAldose reductase1.1.1.210.486
4lcw1VYMajor histocompatibility complex class I-related gene protein/0.486
4pnmNU1Tankyrase-22.4.2.300.485
1zgcA2EAcetylcholinesterase3.1.1.70.484
2ct8MSPMethionine--tRNA ligase6.1.1.100.484
2xugTZ4Acetylcholinesterase3.1.1.70.484
3p2vDOYAldose reductase1.1.1.210.484
2xi4AFTAcetylcholinesterase3.1.1.70.483
4jtrIZPAldo-keto reductase family 1 member C2/0.483
1ut6A8NAcetylcholinesterase3.1.1.70.482
2evcFC3Methionine aminopeptidase/0.482
3fvuIACKynurenine--oxoglutarate transaminase 12.6.1.70.482
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.482
3vilSA0Beta-glucosidase/0.482
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.482
1w87FADFerredoxin--NADP reductase1.18.1.20.481
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.481
3upr1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.481
4jqaID8Aldo-keto reductase family 1 member C2/0.481
2gg8U15Methionine aminopeptidase/0.480
4p9dTMPDeoxycytidylate deaminase/0.480
2p99YE6Methionine aminopeptidase/0.479
2xltNA0Putative flavin-containing monooxygenase/0.479
3h4gFIDAlcohol dehydrogenase [NADP(+)]1.1.1.20.479
4n3l2FNProthrombin3.4.21.50.479
1rkwPNTHTH-type transcriptional regulator QacR/0.478
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.478
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.478
1ta6177Prothrombin3.4.21.50.477
2ckmAA7Acetylcholinesterase3.1.1.70.477
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.477
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.476
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.476
3iu9T07Methionine aminopeptidase 2/0.476
3q9bB3NAcetylpolyamine amidohydrolase/0.476
4mqt2CUMuscarinic acetylcholine receptor M2/0.476
1ry0PG2Aldo-keto reductase family 1 member C3/0.475
1zgbA1EAcetylcholinesterase3.1.1.70.475
2bjsACVIsopenicillin N synthase1.21.3.10.475
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.475
2xuhTZ4Acetylcholinesterase3.1.1.70.475
3ai0PNWBeta-glucosidase/0.475
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.474
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.473
1zuaTOLAldo-keto reductase family 1 member B101.1.10.473
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.473
2q94A04Methionine aminopeptidase/0.473
4azaMGOEukaryotic translation initiation factor 4E/0.473
1hb3SCVIsopenicillin N synthase1.21.3.10.472
1s36CEIObelin/0.472
1yw9A84Methionine aminopeptidase 2/0.472
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.472
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.472
3casASD3-oxo-5-beta-steroid 4-dehydrogenase/0.472
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.472
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.472
1odjGMPPurine nucleoside phosphorylase/0.471
2xufTZ4Acetylcholinesterase3.1.1.70.471
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.471
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3uyk0CXProbable NDP-rhamnosyltransferase/0.471
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.471
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.471
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.471
4jq4IMNAldo-keto reductase family 1 member C2/0.471
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.470
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
2ipjFFAAldo-keto reductase family 1 member C2/0.470
2xujTZ5Acetylcholinesterase3.1.1.70.470
2xukTZ5Acetylcholinesterase3.1.1.70.470
4b7zQ4QAcetylcholinesterase3.1.1.70.470
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
4j7gTRHPCZA361.3/0.470
1jumBERHTH-type transcriptional regulator QacR/0.469
1rxjBNIStreptavidin/0.469
1zq5E04Aldo-keto reductase family 1 member C3/0.469
3dt2GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.469
4arbC57Acetylcholinesterase3.1.1.70.469
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.468
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3klbFMNUncharacterized protein/0.468
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.468
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.468
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.468
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.468
5dsg0HKMuscarinic acetylcholine receptor M4/0.468
1c23MPHMethionine aminopeptidase/0.467
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.467
1obnASVIsopenicillin N synthase1.21.3.10.467
1ry8RUTAldo-keto reductase family 1 member C3/0.467
1s2cFLFAldo-keto reductase family 1 member C3/0.467
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.467
3irhDTPHD domain protein/0.467
4je5PLPAromatic/aminoadipate aminotransferase 12.6.1.390.467
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.467
1mrqSTRAldo-keto reductase family 1 member C1/0.466
1q83TZ5Acetylcholinesterase3.1.1.70.466
2fahGDPPhosphoenolpyruvate carboxykinase [GTP], mitochondrial4.1.1.320.466
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.466
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.466
3uonQNBMuscarinic acetylcholine receptor M2/0.466
1lkeDOGBilin-binding protein/0.465
2iviACWIsopenicillin N synthase1.21.3.10.465
2jf0HBPAcetylcholinesterase3.1.1.70.465
2q92B23Methionine aminopeptidase/0.465
2w3mFOLDihydrofolate reductase1.5.1.30.465
3br3ETHTH-type transcriptional regulator QacR/0.465
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.465
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.465
4flkY10Methionine aminopeptidase 1/0.465
4jq3ZOMAldo-keto reductase family 1 member C2/0.465
4jtrIBPAldo-keto reductase family 1 member C2/0.465
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.464
2jb4A14Isopenicillin N synthase1.21.3.10.464
3g70A5TRenin3.4.23.150.464
3ziuLSSLeucyl-tRNA synthetase/0.464
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
1d3pBT3Prothrombin3.4.21.50.463
1hfrMOTDihydrofolate reductase1.5.1.30.463
1nbhSAMGlycine N-methyltransferase2.1.1.200.463
2gywOBIAcetylcholinesterase3.1.1.70.463
2jl1NAPTriphenylmethane reductase/0.463
4epq0RRPoly(ADP-ribose) glycohydrolase/0.463
4fliY16Methionine aminopeptidase 1/0.463
1bk0ACVIsopenicillin N synthase1.21.3.10.462
1qtiGNTAcetylcholinesterase3.1.1.70.462
2xuqTZ4Acetylcholinesterase3.1.1.70.462
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.462
3pkcY08Methionine aminopeptidase 2/0.462
3t0kDCQSulfide-quinone reductase/0.462
3wqmB29Diterpene synthase3.1.7.80.462
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.462
1w6rGNTAcetylcholinesterase3.1.1.70.461
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.461
2pdlTOLAldose reductase1.1.1.210.461
2wnbC5PCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 12.4.99.40.461
2zevIPEGeranylgeranyl pyrophosphate synthase/0.461
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1xnzFCDMethionine aminopeptidase/0.460
2a3bCFFEndochitinase B13.2.1.140.460
2po3T4K4-dehydrase/0.460
2q93B21Methionine aminopeptidase/0.460
2xupTZ5Acetylcholinesterase3.1.1.70.460
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.460
3g72A6TRenin3.4.23.150.460
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.460
4dk70KSOxysterols receptor LXR-beta/0.460
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.460
4u140HKMuscarinic acetylcholine receptor M3/0.460
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.459
1odcA8BAcetylcholinesterase3.1.1.70.459
1s1rNAPAldo-keto reductase family 1 member C3/0.459
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.459
2g1a5HGClass B acid phosphatase3.1.3.20.459
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.459
2aot2PMHistamine N-methyltransferase2.1.1.80.458
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.458
2qimZEAClass 10 plant pathogenesis-related protein/0.458
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.458
3iu8T03Methionine aminopeptidase 2/0.458
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.458
3to3ATPPetrobactin biosynthesis protein AsbB/0.458
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.458
3znqSS8D-amino-acid oxidase1.4.3.30.458
4ikuSHXMethionine aminopeptidase 1/0.458
1vf3GDNGlutathione S-transferase 32.5.1.180.457
2y6fM9FIsopenicillin N synthase1.21.3.10.457
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.457
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.457
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.457
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.457
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.457
4kn0MTXFolate receptor beta/0.457
4wbdADPPutative cysteine ligase BshC/0.457
1ah3TOLAldose reductase1.1.1.210.456
1dr4HBIDihydrofolate reductase1.5.1.30.456
1ef3FIDAldose reductase1.1.1.210.456
1kyyINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
2aj4ANPGalactokinase2.7.1.60.456
2e82IM3D-amino-acid oxidase1.4.3.30.456
2fs4PZ1Renin3.4.23.150.456
2gvcFADThiol-specific monooxygenase1.14.130.456
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.456
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.456
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.456
4uugPXGBranched-chain amino acid aminotransferase, putative/0.456
5cxv0HKMuscarinic acetylcholine receptor M1/0.456
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.455
1jf0CZHObelin/0.455
1vfsDCSAlanine racemase/0.455
1vkgCRIHistone deacetylase 83.5.1.980.455
2gg0U11Methionine aminopeptidase/0.455
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.455
3oadLPORenin3.4.23.150.455
3rsv3RSBeta-secretase 13.4.23.460.455
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.455
4bfuZVUPantothenate kinase2.7.1.330.455
4jx1CAHCamphor 5-monooxygenase1.14.15.10.455
4kfjFOLDihydrofolate reductase1.5.1.30.455
4xoqF42Coenzyme F420:L-glutamate ligase/0.455
1eveE20Acetylcholinesterase3.1.1.70.454
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
1vftDCSAlanine racemase/0.454
2aovC2MHistamine N-methyltransferase2.1.1.80.454
2g263LGRenin3.4.23.150.454
2gg9U16Methionine aminopeptidase/0.454
2wmdZZ0NmrA-like family domain-containing protein 1/0.454
2xuoTZ4Acetylcholinesterase3.1.1.70.454
2ycnP61Tyrosine phenol-lyase4.1.99.20.454
3gwfFADCyclohexanone monooxygenase/0.454
4a81DXCMajor pollen allergen Bet v 1-A/0.454
4m6kFOLDihydrofolate reductase1.5.1.30.454
4nv7COAArylamine N-acetyltransferase/0.454
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.453
2hzqSTRApolipoprotein D/0.453
2w6pOA4Biotin carboxylase6.3.4.140.453
2wzySQXSoluble acetylcholine receptor/0.453
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.453
3pkeY10Methionine aminopeptidase 2/0.453
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.453
3r8gIZPAldo-keto reductase family 1 member C3/0.453
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.453
4br3U85Choline kinase alpha2.7.1.320.453
4iktTFVMethionine aminopeptidase 1/0.453
4n3r2GUTankyrase-12.4.2.300.453
4tjy3GNTankyrase-22.4.2.300.453
1acjTHAAcetylcholinesterase3.1.1.70.452
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.452
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.452
1uhhCZPAequorin-2/0.452
2b8jADNClass B acid phosphatase3.1.3.20.452
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.452
2xysSY9Soluble acetylcholine receptor/0.452
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.452
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.452
3htjETEbrA repressor/0.452
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.452
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.452
3nxtD2EDihydrofolate reductase1.5.1.30.452
4nv14TGFormyl transferase/0.452
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.451
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.451
1qv0CZHObelin/0.451
1r5gAO1Methionine aminopeptidase 2/0.451
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.451
2gg3U13Methionine aminopeptidase/0.451
2vqqTFGHistone deacetylase 43.5.1.980.451
3h0bB35Beta-secretase 13.4.23.460.451
3hl0NADMaleylacetate reductase/0.451
3rtnRTNBeta-secretase 13.4.23.460.451
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.451
4hlf15ZTankyrase-22.4.2.300.451
4m6l21VDihydrofolate reductase1.5.1.30.451
4nv1TYDFormyl transferase/0.451
1lnmDTXBilin-binding protein/0.450
1pj6FOLDimethylglycine oxidase1.5.3.100.450
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.450
2ipw2CLAldose reductase1.1.1.210.450
2pdh47DAldose reductase1.1.1.210.450
3dgeADPSensor histidine kinase/0.450
3ugrIMNAldo-keto reductase family 1 member C3/0.450
3voiRCBGlucanase/0.450
4bj9UHBTankyrase-22.4.2.300.450
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.450
4l341VGTankyrase-22.4.2.300.450
5ds309LPoly [ADP-ribose] polymerase 12.4.2.300.450
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.449
1z5uCMPClass B acid phosphatase/0.449
2io6330Wee1-like protein kinase2.7.10.20.449
2pd9FIDAldose reductase1.1.1.210.449
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.449
2vi5Y196,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
2xlpFADPutative flavin-containing monooxygenase/0.449
3cv6HXSAldo-keto reductase family 1 member C21/0.449
3e4aQIXInsulin-degrading enzyme3.4.24.560.449
3f0aACOSpermidine N(1)-acetyltransferase/0.449
3gx9TXDMorphinone reductase/0.449
3n0hTOPDihydrofolate reductase1.5.1.30.449
3pkaY02Methionine aminopeptidase 2/0.449
4fljY08Methionine aminopeptidase 1/0.449
4to1DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.449
1blzACVIsopenicillin N synthase1.21.3.10.448
1jdzFMBPurine nucleoside phosphorylase/0.448
1pq944BOxysterols receptor LXR-beta/0.448
1rpwDIDHTH-type transcriptional regulator QacR/0.448
2gmvUN8Phosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.448
2vrjNCWBeta-glucosidase A3.2.1.210.448
3c1kT15Prothrombin3.4.21.50.448
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3l7gM44Xaa-Pro dipeptidase3.4.13.90.448
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.448
4b66NAPL-ornithine N(5)-monooxygenase/0.448
4d6qPD2Lysine-specific demethylase 4D1.14.110.448
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.448
4psbGA3Cytokinin-specific binding protein/0.448
5a4vQUEGlutathione S-transferase F22.5.1.180.448
4u150HKMuscarinic acetylcholine receptor M3/0.448
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.447
1kmsLIHDihydrofolate reductase1.5.1.30.447
1pd8CO4Dihydrofolate reductase1.5.1.30.447
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.447
1xf0ASDAldo-keto reductase family 1 member C3/0.447
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.447
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.447
2wm3NFLNmrA-like family domain-containing protein 1/0.447
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.447
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.447
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3fznD7KBenzoylformate decarboxylase4.1.1.70.447
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
3pqbVGPPutative oxidoreductase/0.447
3ptqNFGBeta-glucosidase 12/0.447
3qwc98PProthrombin3.4.21.50.447
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
4dz5NAPAldo-keto reductase family 1 member C3/0.447
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.446
1hb1OCVIsopenicillin N synthase1.21.3.10.446
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.446
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.446
2j83BATUlilysin3.4.240.446
2lfoGCHFatty acid-binding protein, liver/0.446
2vbdV10Isopenicillin N synthase1.21.3.10.446
2zrxFMNIsopentenyl-diphosphate delta-isomerase/0.446
3b9oFMNAlkane monoxygenase/0.446
3c1oNAPEugenol synthase/0.446
3c35KAIGlutamate receptor ionotropic, kainate 1/0.446
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3r8hZOMAldo-keto reductase family 1 member C3/0.446
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
3v0o4GWHisto-blood group ABO system transferase/0.446
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
4bamMM9Prothrombin3.4.21.50.446
4jtqNAPAldo-keto reductase family 1 member C2/0.446
4y1bNAPAntE/0.446
5dsyUHBPoly [ADP-ribose] polymerase 22.4.2.300.446
1nzq162Prothrombin3.4.21.50.445
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.445
2f3815MAldo-keto reductase family 1 member C3/0.445
2ga2A19Methionine aminopeptidase 2/0.445
2ggbU17Methionine aminopeptidase/0.445
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.445
2vdyHCYCorticosteroid-binding globulin/0.445
2xveFADPutative flavin-containing monooxygenase/0.445
3c4hDRLPoly [ADP-ribose] polymerase 32.4.2.300.445
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3qeoLLTDeoxycytidine kinase2.7.1.740.445
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.445
4bjbP34Tankyrase-22.4.2.300.445
4jzr4JREgl nine homolog 1/0.445
4kn2LYAFolate receptor beta/0.445
4l4v1VYMajor histocompatibility complex class I-related gene protein/0.445
4n9qFMNFMN-dependent NADH-azoreductase 1/0.445
4nqgCZHMitrocomin/0.445
4qg1DTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.445
4rxrDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.445
5d4vYGPUncharacterized protein MJ0489/0.445
5dg3U21Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase/0.445
1dgbNDPCatalase1.11.1.60.444
1ffyMRCIsoleucine--tRNA ligase6.1.1.50.444
1mvsDTMDihydrofolate reductase1.5.1.30.444
1r58AO5Methionine aminopeptidase 2/0.444
1zrb062Prothrombin3.4.21.50.444
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.444
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2vqoTFGHistone deacetylase 43.5.1.980.444
3qgf46FGenome polyprotein2.7.7.480.444
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.444
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.444
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.444
4fllYZ6Methionine aminopeptidase 1/0.444
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.444
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.444
4xo7ASDAldo-keto reductase family 1 member C2/0.444
1e66HUXAcetylcholinesterase3.1.1.70.443
1mxfMTXPutative pteridine reductase 2/0.443
1p33MTXPteridine reductase 11.5.1.330.443
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.443
1ve3SAMUncharacterized protein/0.443
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.443
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.443
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
2wo7ASVIsopenicillin N synthase1.21.3.10.443
2xnvVU3Soluble acetylcholine receptor/0.443
3b9gIMHIAG-nucleoside hydrolase/0.443
3dr7GPDGDP-perosamine synthase/0.443
3f3y4OABile salt sulfotransferase2.8.2.140.443
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.443
3qe2FMNNADPH--cytochrome P450 reductase/0.443
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3qwhKMP17beta-hydroxysteroid dehydrogenase/0.443
3rupADPBiotin carboxylase6.3.4.140.443
3w5uFADFerredoxin/0.443
3zkyWT4Isopenicillin N synthase1.21.3.10.443
4bftZVTPantothenate kinase2.7.1.330.443
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.443
4pabTHGDimethylglycine dehydrogenase, mitochondrial1.5.8.40.443
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.443
3d4sTIMBeta-2 adrenergic receptor/0.443
1e2nRCAThymidine kinase/0.442
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.442
1pqc444Oxysterols receptor LXR-beta/0.442
1s0jMUSTrans-sialidase/0.442
1ye6NAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.442
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.442
2b82ADNClass B acid phosphatase3.1.3.20.442
2bfaCB3Pteridine reductase 11.5.1.330.442
2g274LGRenin3.4.23.150.442
2v8pCDP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.442
2vq7NAPPutative flavin-containing monooxygenase/0.442
2zhw12UProthrombin3.4.21.50.442
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.442
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3i9kNADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase3.2.2.60.442
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3mjrAC2Deoxycytidine kinase2.7.1.740.442
3ocw3AMLipoprotein E/0.442
3ojwFMNNADPH--cytochrome P450 reductase/0.442
3qftFADNADPH--cytochrome P450 reductase/0.442
3rviRVIBeta-secretase 13.4.23.460.442
4a86H35Major pollen allergen Bet v 1-A/0.442
4bz8J38Histone deacetylase/0.442
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.442
4gki0JNAminoglycoside 3'-phosphotransferase AphA1-IAB/0.442
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4ixt1H1Halohydrin dehalogenase/0.442
4jt91NSNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.442
4kn104JFolate receptor beta/0.442
4l321VFTankyrase-22.4.2.300.442
5fd8A5APutative carboxypeptidase yocD/0.442
3ny9JSZBeta-2 adrenergic receptor/0.442
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.441
1amoFADNADPH--cytochrome P450 reductase/0.441
1dx6GNTAcetylcholinesterase3.1.1.70.441
1ex75GPGuanylate kinase2.7.4.80.441
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.441
2ok7A2PFerredoxin--NADP reductase, apicoplast/0.441
2pdfZSTAldose reductase1.1.1.210.441
3c36KAIGlutamate receptor ionotropic, kainate 1/0.441
3d2dRENReticuline oxidase1.21.3.30.441
3ghtLDTAldose reductase1.1.1.210.441
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.441
3uelA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.441
3v2uATPProtein GAL3/0.441
3zo7K6HMuconolactone Delta-isomerase/0.441
4dbuBT9Aldo-keto reductase family 1 member C3/0.441
4j7hTRHPCZA361.3/0.441
4jtqFLPAldo-keto reductase family 1 member C2/0.441
4l6s1WQPoly [ADP-ribose] polymerase 12.4.2.300.441
4paaTHGDimethylglycine dehydrogenase, mitochondrial1.5.8.40.441
4rxqDUTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.441
4x9dU5PUncharacterized protein MJ1435/0.441
4xt8TMQPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.441
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.441
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.441
5d5aCAUBeta-2 adrenergic receptor/0.441
1ej3CZHAequorin-2/0.440
1esmCOAPantothenate kinase2.7.1.330.440
1isjNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.440
1ivrCBAAspartate aminotransferase, mitochondrial2.6.1.10.440
1m2xMCOMetallo-beta-lactamase type 2/0.440
1s3vTQDDihydrofolate reductase1.5.1.30.440
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.440
1yw8A75Methionine aminopeptidase 2/0.440
2cbqTH2Neocarzinostatin/0.440
2ea4F79Methionine aminopeptidase 2/0.440
2fjeFADAdenylylsulfate reductase, subunit A (AprA)/0.440
2gmuPDGPutative pyridoxamine 5-phosphate-dependent dehydrase/0.440
2mt9FMNFlavodoxin 2/0.440
2zryFNRIsopentenyl-diphosphate delta-isomerase/0.440
3arvSAUChitinase A/0.440
3d27W29Methionine aminopeptidase/0.440
3pm1ETHTH-type transcriptional regulator QacR/0.440
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.440
3vhmNPKAvidin/0.440
4c5oFADPutative monooxygenase/0.440
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
4jq1NPSAldo-keto reductase family 1 member C2/0.440
4k88HFGBifunctional glutamate/proline--tRNA ligase6.1.1.150.440