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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4g8bHL6Alpha/beta hydrolase fold protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4g8bHL6Alpha/beta hydrolase fold protein/1.000
4g8cC6LAlpha/beta hydrolase fold protein/0.581
4iarERM5-hydroxytryptamine receptor 1B/0.529
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.520
1pq944BOxysterols receptor LXR-beta/0.513
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.510
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.509
1upw444Oxysterols receptor LXR-beta/0.508
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.508
5uviZMAAdenosine receptor A2a/0.508
3h3r14HCollagen type IV alpha-3-binding protein/0.507
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.505
1pq6965Oxysterols receptor LXR-beta/0.503
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.501
4h4o506Gag-Pol polyprotein2.7.7.490.500
3dolGWIPol protein/0.497
5k2dZMAAdenosine receptor A2a/0.497
5iubCLRAdenosine receptor A2a/0.496
1zdwFLVPrenyltransferase/0.495
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.495
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.495
2wetFADTryptophan 5-halogenase/0.494
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.494
4bb3KKAIsopenicillin N synthase1.21.3.10.494
5k2aZMAAdenosine receptor A2a/0.494
3w6hAZMCarbonic anhydrase 14.2.1.10.493
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.493
4pnmNU1Tankyrase-22.4.2.300.493
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.493
1hb1OCVIsopenicillin N synthase1.21.3.10.492
2po7CHDFerrochelatase, mitochondrial4.99.1.10.491
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.491
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.491
4g67SAHUncharacterized ACR, COG1565 superfamily/0.491
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.490
3nr4PYVAbscisic acid receptor PYL2/0.490
5iu4ZMAAdenosine receptor A2a/0.490
5k2cZMAAdenosine receptor A2a/0.490
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.489
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.488
3emlZMAAdenosine receptor A2a/0.488
1osvCHCBile acid receptor/0.487
2c27ACOMycothiol acetyltransferase2.3.1.1890.487
3zoiM2WIsopenicillin N synthase1.21.3.10.487
3d5fL41Peroxisome proliferator-activated receptor delta/0.486
5iu86DZAdenosine receptor A2a/0.486
2rqfJH3Hemolymph juvenile hormone binding protein/0.485
3h3sH15Collagen type IV alpha-3-binding protein/0.485
4g95OAGDihydrofolate reductase1.5.1.30.485
4h4m494Gag-Pol polyprotein2.7.7.490.485
4jlm1NNDeoxycytidine kinase2.7.1.740.485
4v12POGMaoC like domain protein/0.485
5k2bZMAAdenosine receptor A2a/0.485
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.484
3tdaPN0Cytochrome P450 2D6/0.484
3zkyWT4Isopenicillin N synthase1.21.3.10.484
1p8dCO1Oxysterols receptor LXR-beta/0.483
2vcmM11Isopenicillin N synthase1.21.3.10.483
3aosJH2Hemolymph juvenile hormone binding protein/0.483
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.483
3oquA8SAbscisic acid receptor PYL9/0.483
4iae1DXAlr2278 protein/0.483
5g53NECAdenosine receptor A2a/0.483
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.482
3ddw055Glycogen phosphorylase, liver form2.4.1.10.482
3vrbFTNSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/0.482
3vrbFTNCytochrome b-large subunit/0.482
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.481
2bu9HFVIsopenicillin N synthase1.21.3.10.481
3e01PZ2Gag-Pol polyprotein2.7.7.490.481
4rrxLURProstaglandin G/H synthase 21.14.99.10.481
1a50FIPTryptophan synthase alpha chain/0.480
1hb3SCVIsopenicillin N synthase1.21.3.10.480
1ie9VDXVitamin D3 receptor/0.480
1qiqACCIsopenicillin N synthase1.21.3.10.480
2aclL05Oxysterols receptor LXR-alpha/0.480
2ym1FADPhenylacetone monooxygenase1.14.13.920.480
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.480
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
2fjeFADAdenylylsulfate reductase, subunit A (AprA)/0.479
3c14FOKAdenylate cyclase type 2/0.479
3c14FOKAdenylate cyclase type 5/0.479
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.479
3i0sRT7Gag-Pol polyprotein2.7.7.490.479
3nmpPYVAbscisic acid receptor PYL2/0.479
4iah1DXAlr2278 protein/0.479
1txiTX5Vitamin D3 receptor/0.478
2xlsFADPutative flavin-containing monooxygenase/0.478
2zlcVDXVitamin D3 receptor/0.478
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.478
3oafOAGDihydrofolate reductase1.5.1.30.478
3qlwN22Dihydrofolate reductase1.5.1.30.478
3v49PK0Androgen receptor/0.478
3v94WYQPhosphodiesterase/0.478
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.478
1luqBTNStreptavidin/0.477
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
1db1VDXVitamin D3 receptor/0.476
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.476
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.476
2igyA2TPlasmepsin 2/0.476
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.476
3uyk0CXProbable NDP-rhamnosyltransferase/0.476
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.476
4rw4494Gag-Pol polyprotein2.7.7.490.476
1nenDNTSuccinate dehydrogenase iron-sulfur subunit1.3.5.10.475
1nenDNTSuccinate dehydrogenase cytochrome b556 subunit/0.475
1pqc444Oxysterols receptor LXR-beta/0.475
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.475
1rx8FOLDihydrofolate reductase1.5.1.30.475
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.475
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.475
3dokGWJPol protein/0.475
4bfzZVZPantothenate kinase2.7.1.330.475
1lcwSHMStreptavidin/0.474
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.474
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.474
2fziDH3Dihydrofolate reductase1.5.1.30.474
2igxA1TPlasmepsin 2/0.474
3dr1C5DVitamin D3 receptor A/0.474
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
3dyaPZLGag-Pol polyprotein2.7.7.490.474
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
3frkTQPQdtB/0.474
3qls55VDihydrofolate reductase1.5.1.30.474
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
5jtbZMAAdenosine receptor A2a/0.474
1a5sFIPTryptophan synthase alpha chain/0.473
3da24MDCarbonic anhydrase 134.2.1.10.473
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.473
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.473
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.473
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.473
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.473
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.473
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.473
1f5fDHTSex hormone-binding globulin/0.472
3nga3NGCasein kinase II subunit alpha2.7.11.10.472
4bx7B4FStreptavidin/0.472
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.471
1bk0ACVIsopenicillin N synthase1.21.3.10.471
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.471
1uzwCDHIsopenicillin N synthase1.21.3.10.471
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.471
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
1klkPMDDihydrofolate reductase1.5.1.30.470
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.470
2izlIMIStreptavidin/0.470
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.470
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.470
3b9lAZZSerum albumin/0.470
3h3t16HCollagen type IV alpha-3-binding protein/0.470
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.470
4b1iA8PPoly(ADP-ribose) glycohydrolase3.2.1.1430.470
4h9tHL4Phosphotriesterase/0.470
4mr61K0Bromodomain-containing protein 2/0.470
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.470
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.470
1kt6RTLRetinol-binding protein 4/0.469
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.469
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.469
2ovhAS0Progesterone receptor/0.469
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.469
3gb4D3MDdmC/0.469
4a83DXCMajor pollen allergen Bet v 1-A/0.469
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.469
1rd4L08Integrin alpha-L/0.468
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.468
1s3uTQDDihydrofolate reductase1.5.1.30.468
1v7aFRCAdenosine deaminase3.5.4.40.468
3ipq965Oxysterols receptor LXR-alpha/0.468
3vt65YIVitamin D3 receptor/0.468
4bfvZVVPantothenate kinase2.7.1.330.468
4bfwZVWPantothenate kinase2.7.1.330.468
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.468
4jln18VDeoxycytidine kinase2.7.1.740.468
4rvnCOAPhenylacetate-coenzyme A ligase/0.468
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.468
4ure1PSCyclohexanol dehydrogenase/0.468
2rtoIMIStreptavidin/0.467
2zl9VDAVitamin D3 receptor/0.467
3atzFMNProstaglandin F2a synthase/0.467
3dg8RJ6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.467
3ghvGHCDihydrofolate reductase1.5.1.30.467
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.467
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.467
4blcNDPCatalase1.11.1.60.467
4fm5DF0Prostaglandin G/H synthase 21.14.99.10.467
4mv8ACPBiotin carboxylase6.3.4.140.467
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.467
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.467
4k5y1Q5Corticotropin-releasing factor receptor 1/0.467
1aoeGW3Dihydrofolate reductase1.5.1.30.466
1blzACVIsopenicillin N synthase1.21.3.10.466
1i91INQCarbonic anhydrase 24.2.1.10.466
1mvsDTMDihydrofolate reductase1.5.1.30.466
1pd9CO4Dihydrofolate reductase1.5.1.30.466
1s3vTQDDihydrofolate reductase1.5.1.30.466
1sezFADProtoporphyrinogen oxidase, mitochondrial1.3.3.40.466
1w06W05Isopenicillin N synthase1.21.3.10.466
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.466
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.466
1z6tADPApoptotic protease-activating factor 1/0.466
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.466
2vn0TDZCytochrome P450 2C8/0.466
2y6fM9FIsopenicillin N synthase1.21.3.10.466
3b6zCO7Enoyl reductase LovC10.466
3c1xCKKHepatocyte growth factor receptor2.7.10.10.466
3eem53VUncharacterized protein/0.466
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.466
4fhh0U3Vitamin D3 receptor A/0.466
3sn6P0GBeta-2 adrenergic receptor/0.466
1dg5TOPDihydrofolate reductase1.5.1.30.465
1ia4TQ6Dihydrofolate reductase1.5.1.30.465
1obnASVIsopenicillin N synthase1.21.3.10.465
1sreHABStreptavidin/0.465
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.465
2vbpVB1Isopenicillin N synthase1.21.3.10.465
3atyFMNProstaglandin F2a synthase/0.465
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
3pd3A3TThreonine--tRNA ligase6.1.1.30.465
3vt45YIVitamin D3 receptor/0.465
3w0hW12Vitamin D3 receptor/0.465
4bj9UHBTankyrase-22.4.2.300.465
4dk70KSOxysterols receptor LXR-beta/0.465
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.464
1srhMOBStreptavidin/0.464
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
2izhBTNStreptavidin/0.464
2q70DC8Estrogen receptor/0.464
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.464
3kpzZNEVitamin D3 receptor/0.464
3qlrQLRDihydrofolate reductase1.5.1.30.464
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
4a802ANMajor pollen allergen Bet v 1-A/0.464
4dscA8SAbscisic acid receptor PYL3/0.464
4eiyZMAAdenosine receptor A2a/0.464
4iteTEYVitamin D3 receptor/0.464
4l1xSTRAldo-keto reductase family 1 member C2/0.464
4mlp2CXCryptochrome-2/0.464
4twnB96Ephrin type-A receptor 32.7.10.10.464
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.463
1kt3RTLRetinol-binding protein 4/0.463
1zq5E04Aldo-keto reductase family 1 member C3/0.463
2bpoNAPNADPH--cytochrome P450 reductase/0.463
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
2w6mOA1Biotin carboxylase6.3.4.140.463
2w9hTOPDihydrofolate reductase1.5.1.30.463
3dlgGWEGag-Pol polyprotein2.7.7.490.463
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.463
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3lakKR1Gag-Pol polyprotein2.7.7.490.463
3vrwYS5Vitamin D3 receptor/0.463
4e2dFMNDehydrogenase/0.463
4fhd0TTSpore photoproduct lyase/0.463
4g1y0VOVitamin D3 receptor A/0.463
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
4rujVDXVitamin D3 receptor A/0.463
4rupH97Vitamin D3 receptor A/0.463
4y9lFADAcyl-CoA dehydrogenase family member 11/0.463
5fm7ADPRuvB-like helicase/0.463
5hbsRTLRetinol-binding protein 1/0.463
5iua6DXAdenosine receptor A2a/0.463
1crbRTLRetinol-binding protein 1/0.462
1vf2GTXGlutathione S-transferase 32.5.1.180.462
1zoyUQ1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.462
1zoyUQ1Succinate dehydrogenase cytochrome b560 subunit, mitochondrial/0.462
2gvcFADThiol-specific monooxygenase1.14.130.462
2j9lATPH(+)/Cl(-) exchange transporter 5/0.462
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.462
2zbaZBATrichothecene 3-O-acetyltransferase/0.462
3b9oFMNAlkane monoxygenase/0.462
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.462
3ewrAPRReplicase polyprotein 1a3.4.220.462
3fznD7KBenzoylformate decarboxylase4.1.1.70.462
3pqbVGPPutative oxidoreductase/0.462
3zkuHCVIsopenicillin N synthase1.21.3.10.462
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.462
4q0kGA3Phytohormone-binding protein/0.462
1cjkFOKAdenylate cyclase type 2/0.461
1cjkFOKAdenylate cyclase type 5/0.461
1e7aPFLSerum albumin/0.461
1kmsLIHDihydrofolate reductase1.5.1.30.461
1xuoLA1Integrin alpha-L/0.461
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.461
2r0cFADPutative FAD-monooxygenase/0.461
2tpsTPSThiamine-phosphate synthase/0.461
3bloQEIQueuine tRNA-ribosyltransferase2.4.2.290.461
3dccD9ZCarbonic anhydrase 24.2.1.10.461
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.461
3lanKBTGag-Pol polyprotein2.7.7.490.461
3lkhLT6Genome polyprotein2.7.7.480.461
3vt7VDXVitamin D3 receptor/0.461
4ia3BIVVitamin D3 receptor A/0.461
4jucTPPBenzoylformate decarboxylase4.1.1.70.461
4nieNBHNuclear receptor ROR-gamma/0.461
5hs1VORLanosterol 14-alpha demethylase/0.461
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.460
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.460
1ot7IU5Bile acid receptor/0.460
1rh3MTXDihydrofolate reductase1.5.1.30.460
1yrxFMNAppA protein/0.460
2bxqIMNSerum albumin/0.460
2xvw9NRSerum albumin/0.460
2zaxCAMCamphor 5-monooxygenase1.14.15.10.460
3eej53RUncharacterized protein/0.460
3fnu006HAP protein/0.460
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.460
3oimVZ5Carbonic anhydrase 24.2.1.10.460
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.460
3s79ASDAromatase1.14.14.140.460
4ejh0QACytochrome P450 2A131.14.14.10.460
4li61XOTankyrase-12.4.2.300.460
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.460
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.460
1m79MQ1Dihydrofolate reductase1.5.1.30.459
1oyaFMNNADPH dehydrogenase 11.6.99.10.459
2gpjFADSiderophore-interacting protein/0.459
2hamC33Vitamin D3 receptor/0.459
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.459
2rm2W43Genome polyprotein/0.459
2zscBTNTamavidin2/0.459
3cseN22Uncharacterized protein/0.459
3pd2A3SThreonine--tRNA ligase6.1.1.30.459
3vtbTKAVitamin D3 receptor/0.459
3w0yDS4Vitamin D3 receptor/0.459
4bfsZVSPantothenate kinase2.7.1.330.459
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4du6GTPGTP cyclohydrolase 1/0.459
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.459
4mfb29TGag-Pol polyprotein2.7.7.490.459
4qzuRTLRetinol-binding protein 2/0.459
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.459
1mvtDTMDihydrofolate reductase1.5.1.30.458
1qjfACSIsopenicillin N synthase1.21.3.10.458
1sze173Cytochrome b2, mitochondrial1.1.2.30.458
2ar8FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.458
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.458
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.458
2yloTESAndrogen receptor/0.458
2zlaVDBVitamin D3 receptor/0.458
3a1l2CCCytochrome P450/0.458
3a783EVVitamin D3 receptor/0.458
3elySAHMethyltransferase/0.458
3szfDCQSulfide-quinone reductase/0.458
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.458
3vrtYS2Vitamin D3 receptor/0.458
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.458
4j6bPLOCytochrome P450 monooxygenase/0.458
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.458
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.457
1df7MTXDihydrofolate reductase1.5.1.30.457
1fmjRTLRetinol dehydratase/0.457
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.457
1fxfMJIPhospholipase A2, major isoenzyme3.1.1.40.457
1ia3TQ5Dihydrofolate reductase1.5.1.30.457
1x8lOXRRetinol dehydratase/0.457
2cjfRP43-dehydroquinate dehydratase4.2.1.100.457
2iyaZIOOleandomycin glycosyltransferase/0.457
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.457
2rtfBTNStreptavidin/0.457
2vbdV10Isopenicillin N synthase1.21.3.10.457
2wsiFADFAD synthase2.7.7.20.457
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
2zhw12UProthrombin3.4.21.50.457
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.457
3g70A5TRenin3.4.23.150.457
3ixp834Ecdysone receptor/0.457
3t8xT8XT-cell surface glycoprotein CD1b/0.457
3w5rLOAVitamin D3 receptor/0.457
4at0FADPossible succinate dehydrogenase/0.457
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.457
4itfTFYVitamin D3 receptor/0.457
4jq4IMNAldo-keto reductase family 1 member C2/0.457
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.457
4z9g1Q5Corticotropin-releasing factor receptor 1/0.457
1e2nRCAThymidine kinase/0.456
2bfpH4BPteridine reductase 11.5.1.330.456
2c4iBTNAvidin/0.456
2fzhDH1Dihydrofolate reductase1.5.1.30.456
2hc4VDXVitamin D3 receptor A/0.456
2iviACWIsopenicillin N synthase1.21.3.10.456
2ociTYCValacyclovir hydrolase3.10.456
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.456
2xvv9DNSerum albumin/0.456
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.456
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.456
3pm1ETHTH-type transcriptional regulator QacR/0.456
3t3r9PLCytochrome P450 2A61.14.130.456
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.456
4bmpFMNProtein NrdI/0.456
4epq0RRPoly(ADP-ribose) glycohydrolase/0.456
4g1d0VKVitamin D3 receptor A/0.456
4g1z0VPVitamin D3 receptor A/0.456
4gh5NADShort-chain dehydrogenase/reductase SDR/0.456
4h9753SDihydrofolate reductase1.5.1.30.456
4m6l21VDihydrofolate reductase1.5.1.30.456
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.456
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.456
1dr2TAPDihydrofolate reductase1.5.1.30.455
1fvpFMANon-fluorescent flavoprotein/0.455
1if5FBTCarbonic anhydrase 24.2.1.10.455
1jpaANPEphrin type-B receptor 22.7.10.10.455
1pr9NAPL-xylulose reductase1.1.1.100.455
1ra8FOLDihydrofolate reductase1.5.1.30.455
2aa71CAMineralocorticoid receptor/0.455
2dhfDZFDihydrofolate reductase1.5.1.30.455
2dvlFADAcyl-CoA dehydrogenase/0.455
2hasC3OVitamin D3 receptor/0.455
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.455
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.455
2wggTLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.455
3dmjGWEPol protein/0.455
3t0kDCQSulfide-quinone reductase/0.455
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.455
4a862ANMajor pollen allergen Bet v 1-A/0.455
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.455
4fhi0S4Vitamin D3 receptor A/0.455
4k9pTPPBenzoylformate decarboxylase4.1.1.70.455
4oal245Cytokinin dehydrogenase 4/0.455
7stdCRPScytalone dehydratase4.2.1.940.455
3qakUKAAdenosine receptor A2a/0.455
1g28FMNPHY3/0.454
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
1qknRALEstrogen receptor beta/0.454
1rkhVD2Vitamin D3 receptor/0.454
1zrzBI1Protein kinase C iota type2.7.11.130.454
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.454
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.454
2fszOHTEstrogen receptor beta/0.454
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.454
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.454
2pmdGNPTranslation initiation factor 2 subunit gamma/0.454
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.454
2rh9IGPTryptophan synthase alpha chain/0.454
2v59LZKBiotin carboxylase6.3.4.140.454
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.454
3gl2D3MDdmC/0.454
3kb0A8SAbscisic acid receptor PYL2/0.454
3p6nDSOCamphor 5-monooxygenase1.14.15.10.454
3v4aPK1Androgen receptor/0.454
3vruYS3Vitamin D3 receptor/0.454
3w78CBDFMN-dependent NADH-azoreductase/0.454
4c2jCOA3-ketoacyl-CoA thiolase, mitochondrial2.3.1.160.454
4e2bFMNDehydrogenase/0.454
4h9506UDihydrofolate reductase1.5.1.30.454
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.454
3vw7VPXProteinase-activated receptor 1/0.454
1kl2FONSerine hydroxymethyltransferase/0.453
1klmSPPGag-Pol polyprotein2.7.7.490.453
1kt7RTLRetinol-binding protein 4/0.453
1ml6GBXGlutathione S-transferase A22.5.1.180.453
1oc1ASVIsopenicillin N synthase1.21.3.10.453
1rt2TNKGag-Pol polyprotein2.7.7.490.453
1rxhBNIStreptavidin/0.453
1s36CEIObelin/0.453
1srgMHBStreptavidin/0.453
2acwUPGGlycosyltransferase/0.453
2ardFDAFlavin-dependent tryptophan halogenase PrnA1.14.19.90.453
2fhnBNIAvidin-related protein 4/5/0.453
2g44T3OEstrogen receptor/0.453
2rhgIGPTryptophan synthase alpha chain/0.453
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.453
3dds26BGlycogen phosphorylase, liver form2.4.1.10.453
3di6PDZGag-Pol polyprotein2.7.7.490.453
3dleGFAGag-Pol polyprotein2.7.7.490.453
3imgBZ2Pantothenate synthetase6.3.2.10.453
3w9rA8SAbscisic acid receptor PYL9/0.453
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4jqh1MFAlr2278 protein/0.453
4jvr1MTE3 ubiquitin-protein ligase Mdm26.3.20.453
4k7aDHTAndrogen receptor/0.453
4kf1HT5Aryldialkylphosphatase3.1.8.10.453
4l0qNADAlcohol dehydrogenase class-3/0.453
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.453
5c1mCLRMu-type opioid receptor/0.453
5ikrID8Prostaglandin G/H synthase 21.14.99.10.453
1dhfFOLDihydrofolate reductase1.5.1.30.452
1wxjIPLTryptophan synthase alpha chain/0.452
1zsbAZMCarbonic anhydrase 24.2.1.10.452
2be2R22Gag-Pol polyprotein2.7.7.490.452
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.452
2fzjDH3Dihydrofolate reductase1.5.1.30.452
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.452
2o4jVD4Vitamin D3 receptor/0.452
2pnuENMAndrogen receptor/0.452
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
3c3xNAPEugenol synthase 11.1.1.3180.452
3eon341Glutaryl-CoA dehydrogenase/0.452
3h3qH13Collagen type IV alpha-3-binding protein/0.452
3mytEQUSteroid Delta-isomerase5.3.3.10.452
3qly55VUncharacterized protein/0.452
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
3t1a5MAGag-Pol polyprotein2.7.7.490.452
3vhhVHHAvidin/0.452
3vt5YI2Vitamin D3 receptor/0.452
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.452
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.452
4n1gCEIObelin/0.452
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
4tuvCPZCytochrome P450 1191.140.452
5cdtPFBAlcohol dehydrogenase E chain1.1.1.10.452
4zj8SUVOrexin receptor type 1/0.452
1l8qADPChromosomal replication initiator protein DnaA/0.451
1n1eNDEGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.451
1nm6L86Prothrombin3.4.21.50.451
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.451
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.451
1txtCAAHMG-CoA synthase/0.451
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.451
1xj7DHTAndrogen receptor/0.451
1ygkRRCPyridoxal kinase2.7.1.350.451
2clhF19Tryptophan synthase alpha chain/0.451
2pauD5M5'-deoxynucleotidase YfbR/0.451
2w6oOA3Biotin carboxylase6.3.4.140.451
3bi5FADPolyamine oxidase FMS1/0.451
3q43D66M1 family aminopeptidase3.4.110.451
3siiA1RUncharacterized protein/0.451
4cfbOM3Integrase/0.451
4cjqVXOIntegrase/0.451
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.451
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.451
4j0s1H3Bromodomain-containing protein 4/0.451
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
4tkg09LTankyrase-22.4.2.300.451
4umyNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.451
4wa9AXITyrosine-protein kinase ABL12.7.10.20.451
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.451
5cdsPFBAlcohol dehydrogenase E chain1.1.1.10.451
3pwhZMAAdenosine receptor A2a/0.451
1dr3TAPDihydrofolate reductase1.5.1.30.450
1g45FSBCarbonic anhydrase 24.2.1.10.450
1g6oADPCag alpha/0.450
1h35R01Squalene--hopene cyclase4.2.1.1290.450
1q6t600Tyrosine-protein phosphatase non-receptor type 13.1.3.480.450
1s0zEB1Vitamin D3 receptor/0.450
1swpBTNStreptavidin/0.450
1u0hFOKAdenylate cyclase type 2/0.450
1u0hFOKAdenylate cyclase type 5/0.450
1x7e244Estrogen receptor/0.450
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
1yinCM3Estrogen receptor/0.450
2dvoITTdITP/XTP pyrophosphatase3.6.1.190.450
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.450
2p5uNADUDP-glucose 4-epimerase/0.450
2qenADPWalker-Type ATPase/0.450
2qpyDHTAndrogen receptor/0.450
2qw034Z4-chlorobenzoyl CoA ligase/0.450
2rr1W8RGenome polyprotein/0.450
2rtmIMIStreptavidin/0.450
2vmyFFOSerine hydroxymethyltransferase/0.450
2y60M8FIsopenicillin N synthase1.21.3.10.450
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3c6uM22Gag-Pol polyprotein2.7.7.490.450
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3f3y4OABile salt sulfotransferase2.8.2.140.450
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.450
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.450
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3w0jT08Vitamin D3 receptor/0.450
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.450
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4g210VPVitamin D3 receptor A/0.450
4j26ESTEstrogen receptor beta/0.450
4klaCHDFerrochelatase, mitochondrial4.99.1.10.450
4la7A1OAbscisic acid receptor PYL2/0.450
4nhmUN9Prolyl 3,4-dihydroxylase TPA11.14.110.450
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.450
5cc9DDFDihydrofolate reductase1.5.1.30.450
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.450
1bwlFMNNADPH dehydrogenase 11.6.99.10.449
1cqp803Integrin alpha-L/0.449
1ia1NDPDihydrofolate reductase1.5.1.30.449
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1rj6AZMCarbonic anhydrase 144.2.1.10.449
1v79FR7Adenosine deaminase3.5.4.40.449
1yhjR6CPyridoxal kinase2.7.1.350.449
2fbwCBESuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.449
2fbwCBESuccinate dehydrogenase cytochrome b, large subunit/0.449
2ftoCB3Thymidylate synthase/0.449
2g263LGRenin3.4.23.150.449
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.449
2harOCCVitamin D3 receptor/0.449
2izfBTNStreptavidin/0.449
2p9dSAHDiphthine synthase/0.449
2w71L23Biotin carboxylase6.3.4.140.449
2xgs44PUncharacterized protein/0.449
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3eek53SUncharacterized protein/0.449
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
3t88S0N1,4-dihydroxy-2-naphthoyl-CoA synthase/0.449
3w5p4OAVitamin D3 receptor/0.449
4ap1NAPSteroid monooxygenase/0.449
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4jbtASDCytochrome P450 monooxygenase/0.449
4l5b1UXDeoxycytidine kinase2.7.1.740.449
1c1bGCAGag-Pol polyprotein2.7.7.490.448
1cd2FOLDihydrofolate reductase1.5.1.30.448
1dr3HBIDihydrofolate reductase1.5.1.30.448
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1ie8KH1Vitamin D3 receptor/0.448
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1kt5RTLRetinol-binding protein 4/0.448
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
1ppjANYCytochrome b/0.448
1rk3VDXVitamin D3 receptor/0.448
1tdrMTXDihydrofolate reductase1.5.1.30.448
1tvrTB9Gag-Pol polyprotein2.7.7.490.448
1u3s797Estrogen receptor beta/0.448
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.448
1xq3R18Androgen receptor/0.448
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
2bxmIMNSerum albumin/0.448
2hb8MVDVitamin D3 receptor/0.448
2hr8SAHDiphthine synthase/0.448
2jb4A14Isopenicillin N synthase1.21.3.10.448
2jgsBTNAvidin/0.448
2r0pK2CPutative FAD-monooxygenase/0.448
2rteBTNStreptavidin/0.448
2zi53L1Deoxycytidine kinase2.7.1.740.448
3d4bDZDNAD-dependent protein deacetylase/0.448
3mqe416Prostaglandin G/H synthase 21.14.99.10.448
3w0c6DSVitamin D3 receptor/0.448
3zlnH0YBcl-2-like protein 1/0.448
3zqtTESAndrogen receptor/0.448
4cmfPXGUncharacterized protein/0.448
4fv7E94Mitogen-activated protein kinase 12.7.11.240.448
4g2i0VQVitamin D3 receptor/0.448
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.448
4ia7BIVVitamin D3 receptor A/0.448
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.448
4kjjFOLDihydrofolate reductase1.5.1.30.448
4o1mNADEnoyl-acyl carrier reductase/0.448
4ojb198Androgen receptor/0.448
4py243EMethionine--tRNA ligase/0.448
4z87GDPInosine-5'-monophosphate dehydrogenase/0.448
5irnADPNucleotide binding oligomerization domain containing 2/0.448
1adfTADAlcohol dehydrogenase E chain1.1.1.10.447
1bn3AL6Carbonic anhydrase 24.2.1.10.447
1dg7WRBDihydrofolate reductase1.5.1.30.447
1l0lFMXCytochrome b/0.447
1nlmUD1UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase/0.447
1pxxDIFProstaglandin G/H synthase 21.14.99.10.447
1tj0FADBifunctional protein PutA1.5.5.20.447
1xzqFONtRNA modification GTPase MnmE3.6.50.447
1yc2NADNAD-dependent protein deacylase 2/0.447
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.447
2cleF6FTryptophan synthase alpha chain/0.447
2fdyD4GCytochrome P450 2A61.14.130.447
2hb7O1CVitamin D3 receptor/0.447
2ij7TPFMycocyclosin synthase1.14.21.90.447
2iwuNP5ATP-dependent molecular chaperone HSP82/0.447
2trsIPLTryptophan synthase alpha chain/0.447
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.447
2x7hPFNProstaglandin reductase 310.447
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.447
2z7gEH9Adenosine deaminase3.5.4.40.447
2zjwREFCasein kinase II subunit alpha2.7.11.10.447
2zuiCAMCamphor 5-monooxygenase1.14.15.10.447
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.447
3d73NBBPheromone-binding protein ASP1/0.447
3gncQQQGlutaryl-CoA dehydrogenase/0.447
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.447
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
3hu1AGSTransitional endoplasmic reticulum ATPase3.6.4.60.447
3nrcTCLEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
3ry2BTNStreptavidin/0.447
3u8hBHPPhospholipase A2, membrane associated/0.447
3zc3NAPFerredoxin--NADP reductase1.18.1.20.447
4a6eASEAcetylserotonin O-methyltransferase2.1.1.40.447
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
4dpy2P0Mevalonate diphosphate decarboxylase/0.447
4flpJQ1Bromodomain testis-specific protein/0.447
4g8zTOPDihydrofolate reductase1.5.1.30.447
4glx0XSDNA ligase6.5.1.20.447
4j1p1K0Bromodomain-containing protein 2/0.447
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.447
4wriOKAOkadaic acid binding protein 2-alpha/0.447
4xugF9FTryptophan synthase alpha chain/0.447
1ddrMTXDihydrofolate reductase1.5.1.30.446
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1h51FMNPentaerythritol tetranitrate reductase/0.446
1kqgHQOFormate dehydrogenase, nitrate-inducible, cytochrome b556(Fdn) subunit/0.446
1rfuADPPyridoxal kinase2.7.1.350.446
1s9qOHTEstrogen-related receptor gamma/0.446
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.446
1vj3TABDihydrofolate reductase1.5.1.30.446
1w4zNAPPutative ketoacyl reductase1.3.10.446
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.446
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.446
2f3815MAldo-keto reductase family 1 member C3/0.446
2hcdBIVVitamin D3 receptor A/0.446
2rhrEMOPutative ketoacyl reductase1.3.10.446
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.446
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.446
3ielU5PRibonuclease TTHA02523.10.446
3ol5SAWCamphor 5-monooxygenase1.14.15.10.446
3qeoLLTDeoxycytidine kinase2.7.1.740.446
3qykIE2Carbonic anhydrase 24.2.1.10.446
3s3vTOPDihydrofolate reductase1.5.1.30.446
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4f700STCyclin-dependent kinase 82.7.11.220.446
4hh0FMNAppA protein/0.446
4i1nFOLDihydrofolate reductase1.5.1.30.446
4l9kEHFSerum albumin/0.446
4nfhPFBAlcohol dehydrogenase E chain1.1.1.10.446
4o701QKBromodomain-containing protein 4/0.446
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.446
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.446
4tjy3GNTankyrase-22.4.2.300.446
4yvbBTNStreptavidin/0.446
1bsvNDPGDP-L-fucose synthase/0.445
1fmlRTLRetinol dehydratase/0.445
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.445
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.445
1mk5BTNStreptavidin/0.445
1p4mADPRiboflavin kinase2.7.1.260.445
1uhhCZPAequorin-2/0.445
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.445
1ygjRMCPyridoxal kinase2.7.1.350.445
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.445
2a9y26AAdenosine kinase2.7.1.200.445
2ao6R18Androgen receptor/0.445
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.445
2e0nSAHPrecorrin-2 C20-methyltransferase/0.445
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.445
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.445
2jh6894Prothrombin3.4.21.50.445
2v34CTN4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.445
3aw9NADNAD-dependent epimerase/dehydratase/0.445
3biz61EWee1-like protein kinase2.7.10.20.445
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.445
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.445
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3k1wBFXRenin3.4.23.150.445
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.445
3pe2E1BCasein kinase II subunit alpha2.7.11.10.445
3q44D50M1 family aminopeptidase3.4.110.445
3vg9ZMAAdenosine receptor A2a/0.445
3vt8YI3Vitamin D3 receptor/0.445
3vtdTKDVitamin D3 receptor/0.445
3w0aDS5Vitamin D3 receptor/0.445
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.445
4dc0NDPPutative ketoacyl reductase1.3.10.445
4jhiEMUNodulin-13/0.445
4jtrIBPAldo-keto reductase family 1 member C2/0.445
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4nqgCZHMitrocomin/0.445
4q0a4OAVitamin D3 receptor A/0.445
5difGNPGTP-binding nuclear protein Ran/0.445
1dtpAPUDiphtheria toxin/0.444
1fm4DXCMajor pollen allergen Bet v 1-L/0.444
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.444
1lf3EH5Plasmepsin-23.4.23.390.444
1u3r338Estrogen receptor beta/0.444
1umcTDP2-oxoisovalerate dehydrogenase subunit alpha1.2.4.40.444
1umcTDP2-oxoisovalerate dehydrogenase subunit beta1.2.4.40.444
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2x7jTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.444
2xw19NVSerum albumin/0.444
2ylwFADPhenylacetone monooxygenase1.14.13.920.444
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.444
3gtsD3MDdmC/0.444
3gwfNAPCyclohexanone monooxygenase/0.444
3ibqATPPyridoxal kinase/0.444
3jpuTY4Transcriptional activator protein LasR/0.444
3mtfA3FActivin receptor type-12.7.11.300.444
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.444
3uylTYDProbable NDP-rhamnosyltransferase/0.444
4a9iP9IBromodomain-containing protein 2/0.444
4b5pACOAlpha-tubulin N-acetyltransferase 1/0.444
4dneDTBStreptavidin/0.444
4e9aQAPPeptide deformylase/0.444
4fkxCDPNucleoside diphosphate kinase/0.444
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.444
4gg1TZDBenzoylformate decarboxylase4.1.1.70.444
4h9614QDihydrofolate reductase1.5.1.30.444
4j0r1H2Bromodomain-containing protein 4/0.444
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.444
4kne1CYDihydrofolate reductase1.5.1.30.444
4m4821BSodium-dependent dopamine transporter/0.444
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.444
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
1ddsMTXDihydrofolate reductase1.5.1.30.443
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.443
1jf0CZHObelin/0.443
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.443
1u1d181Uridine phosphorylase2.4.2.30.443
1upcTPPN(2)-(2-carboxyethyl)arginine synthase/0.443
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.443
2b5j3ACGag-Pol polyprotein2.7.7.490.443
2bf7HBIPteridine reductase 11.5.1.330.443
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2in6839Wee1-like protein kinase2.7.10.20.443
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2wp9CBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.443
2wp9CBESuccinate dehydrogenase cytochrome b556 subunit/0.443
2wu2CBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.443
2wu2CBESuccinate dehydrogenase cytochrome b556 subunit/0.443
2x6tNAPADP-L-glycero-D-manno-heptose-6-epimerase/0.443
2xvfFADPutative flavin-containing monooxygenase/0.443
3akkADPSerine/threonine-protein kinase CtkA2.7.11.10.443
3drcMTXDihydrofolate reductase1.5.1.30.443
3fp0FP015-O-acetyltransferase/0.443
3ix9MTXDihydrofolate reductase1.5.1.30.443
3nmhPYVAbscisic acid receptor PYL2/0.443
3q5pTACMultidrug-efflux transporter 1 regulator/0.443
3qiyQI1Botulinum neurotoxin type A3.4.24.690.443
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3vdqNAD3-hydroxybutyrate dehydrogenase/0.443
3znqSS8D-amino-acid oxidase1.4.3.30.443
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.443
4b4w9L9Bifunctional protein FolD/0.443
4bfxZVXPantothenate kinase2.7.1.330.443
4c1fX8ZMetallo-beta-lactamase type 2/0.443
4chyC5QIntegrase/0.443
4g20484Vitamin D3 receptor A/0.443
4k6mSAHGenome polyprotein/0.443
4r1lADPPhenylacetate-coenzyme A ligase/0.443
4r20AERCytochrome P450 family 17 polypeptide 2/0.443
4rrrA3TThreonine--tRNA ligase6.1.1.30.443
4ruoBIVVitamin D3 receptor A/0.443
4yntFDAGlucose oxidase, putative/0.443
5d3fFSC14-3-3 protein zeta/delta/0.443
8catNDPCatalase1.11.1.60.443
1hk4T44Serum albumin/0.442
1hniAAAGag-Pol polyprotein2.7.7.490.442
1lczBH7Streptavidin/0.442
1o6qR17Squalene--hopene cyclase4.2.1.1290.442
1q6s214Tyrosine-protein phosphatase non-receptor type 13.1.3.480.442
1rtiHEFGag-Pol polyprotein2.7.7.490.442
1yplRA8Prothrombin3.4.21.50.442
2aylFLPProstaglandin G/H synthase 11.14.99.10.442
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.442
2g274LGRenin3.4.23.150.442
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.442
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.442
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
2p6lSAHDiphthine synthase/0.442
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
2vqoTFGHistone deacetylase 43.5.1.980.442
2z4jDHTAndrogen receptor/0.442
3arvSAUChitinase A/0.442
3dcsMZMCarbonic anhydrase 24.2.1.10.442
3dv0TPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.442
3dv0TPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.442
3fr5I4AFatty acid-binding protein, adipocyte/0.442
3i587NA2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase/0.442
3l0lHC3Nuclear receptor ROR-gamma/0.442
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.442
3nxxNDPDihydrofolate reductase1.5.1.30.442
3o3jBB4Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.442
3r6pA8SAbscisic acid receptor PYL10/0.442
3t195MAGag-Pol polyprotein2.7.7.490.442
3thrC2FGlycine N-methyltransferase2.1.1.200.442
3wrmCAMCamphor 5-monooxygenase1.14.15.10.442
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4an4DUDPutative glycosyl transferase/0.442
4bftZVTPantothenate kinase2.7.1.330.442
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.442
4hlwTESAndrogen receptor/0.442
4iyg1HUStrictosidine synthase4.3.3.20.442
4j6cSTRCytochrome P450 monooxygenase/0.442
4orkGDPBifunctional AAC/APH2.3.10.442
4otyLURProstaglandin G/H synthase 21.14.99.10.442
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.442
4wudANPDNA gyrase subunit B/0.442
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.442
4zm6ACON-acetyl-beta-D glucosaminidase/0.442
5agyGTBTau class glutathione S-transferase/0.442
5h8tRTLRetinol-binding protein 1/0.442
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.442
1g60SAMModification methylase MboII2.1.1.720.441
1icqOPD12-oxophytodienoate reductase 11.3.1.420.441
1mrqSTRAldo-keto reductase family 1 member C1/0.441
1mxtFAECholesterol oxidase1.1.3.60.441
1pt8ACOFormyl-CoA:oxalate CoA-transferase/0.441
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.441
1tkaN3TTransketolase 12.2.1.10.441
1u65CP0Acetylcholinesterase3.1.1.70.441
1x7jGENEstrogen receptor beta/0.441
2fs4PZ1Renin3.4.23.150.441
2rs1W84Genome polyprotein/0.441
2yltFADPhenylacetone monooxygenase1.14.13.920.441
3akm11DFatty acid-binding protein, intestinal/0.441
3bi2FADPolyamine oxidase FMS1/0.441
3fu83DMLaccase-11.10.3.20.441
3g7jGTXGlutathione transferase GST1-4/0.441
3ha5SFGHydroxymycolate synthase MmaA42.1.10.441
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
3i0rRT3Gag-Pol polyprotein2.7.7.490.441
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.441
3n39FMNProtein NrdI/0.441
3n8yDIFProstaglandin G/H synthase 11.14.99.10.441
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3otqMZLBifunctional epoxide hydrolase 23.3.2.100.441
3rvhHQ2Lysine-specific demethylase 4A1.14.110.441
3sfh1DIHistone deacetylase 83.5.1.980.441
3sigAR6Uncharacterized protein/0.441
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
3wznBTNStreptavidin/0.441
3zc3FADFerredoxin--NADP reductase1.18.1.20.441
4a9nA9NBromodomain-containing protein 2/0.441
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.441
4ead0NPThymidine phosphorylase2.4.2.40.441
4esoNAPPutative oxidoreductase/0.441
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.441
4ia1BIVVitamin D3 receptor A/0.441
4ihiNADProbable pyrroline-5-carboxylate dehydrogenase RocA/0.441
4jlk1NODeoxycytidine kinase2.7.1.740.441
4nh82LCHeat shock protein HSP 90-alpha/0.441
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.441
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.441
5ab6CAANonspecific lipid-transfer protein, putative/0.441
4s0vSUVOrexin receptor type 2/0.441
1ay0TPPTransketolase 12.2.1.10.440
1d6w00RProthrombin3.4.21.50.440
1df8BTNStreptavidin/0.440
1e92HBIPteridine reductase 11.5.1.330.440
1fxsNAPGDP-L-fucose synthase/0.440
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
1kh3ANPArgininosuccinate synthase/0.440
1mepBTNStreptavidin/0.440
1n83CLRNuclear receptor ROR-alpha/0.440
1q6nP90Tyrosine-protein phosphatase non-receptor type 13.1.3.480.440
1rf9DBRCamphor 5-monooxygenase1.14.15.10.440
1s19MC9Vitamin D3 receptor/0.440
1swpBTQStreptavidin/0.440
1ttm667Carbonic anhydrase 24.2.1.10.440
1uhjCZBAequorin-2/0.440
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1yye196Estrogen receptor beta/0.440
2aviBTNAvidin/0.440
2ek3SAHDiphthine synthase/0.440
2hx44HXNitric oxide synthase, brain1.14.13.390.440
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.440
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.440
2mokFMNFlavodoxin 1/0.440
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.440
2v58LZJBiotin carboxylase6.3.4.140.440
2wsbNADGalactitol dehydrogenase/0.440
3br3ETHTH-type transcriptional regulator QacR/0.440
3e6c3C4Cyclic nucleotide-binding protein/0.440
3ia4MTXDihydrofolate reductase/0.440
3jynNDPQuinone oxidoreductase/0.440
3kjm245Cytokinin dehydrogenase 11.5.99.120.440
3lqfNADGalactitol dehydrogenase/0.440
3lxeTORCarbonic anhydrase 14.2.1.10.440
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3nbpJGZGag-Pol polyprotein2.7.7.490.440
3p67FMNPentaerythritol tetranitrate reductase/0.440
3p6pA6BCamphor 5-monooxygenase1.14.15.10.440
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.440
3qftNAPNADPH--cytochrome P450 reductase/0.440
3qlxQLRUncharacterized protein/0.440
3qm4PN0Cytochrome P450 2D6/0.440
3rg9WRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
4aosNAPSteroid monooxygenase/0.440
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.440
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
4ele31IDihydrofolate reductase/0.440
4fhf0TTSpore photoproduct lyase/0.440
4g7gVFVLanosterol 14-alpha-demethylase/0.440
4gdaBTNStreptavidin/0.440
4h2nFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.440
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.440
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.440
4l8u9AZSerum albumin/0.440
4lrg1XBBromodomain-containing protein 4/0.440
4o95245Cytokinin dehydrogenase 4/0.440
4uyg73BBromodomain-containing protein 2/0.440
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.440