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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.11.000
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.757
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.747
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.734
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.719
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.709
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.706
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.652
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.648
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.645
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.641
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.640
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.637
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.634
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.634
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.633
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.633
2hog710Serine/threonine-protein kinase Chk12.7.11.10.632
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.632
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.627
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.623
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.617
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.614
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.613
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.612
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.611
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.608
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.607
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.605
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.605
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.603
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.601
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.598
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.598
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.597
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.596
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.595
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.595
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.595
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.595
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.590
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.589
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.589
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.589
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.588
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.588
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.586
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.586
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.585
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.584
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.584
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.578
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.577
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.577
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.575
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.574
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.572
1zys199Serine/threonine-protein kinase Chk12.7.11.10.570
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.568
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.567
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.566
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.566
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.565
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.565
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.565
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.565
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.563
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.563
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.562
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.562
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.559
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.558
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.557
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.556
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.555
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.554
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.552
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.552
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.552
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.549
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.549
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.548
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.548
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.547
4qmpDKISerine/threonine-protein kinase 242.7.11.10.546
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.546
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.546
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.545
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.544
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.543
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.543
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.542
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.542
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.541
3gubGUBDeath-associated protein kinase 12.7.11.10.540
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.540
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.539
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.539
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.539
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.537
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.537
3zh8C58Protein kinase C iota type2.7.11.130.537
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.535
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.535
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.535
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.532
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.532
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.530
2i40BLZCyclin-dependent kinase 22.7.11.220.530
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.530
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.530
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.530
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.529
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.529
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.529
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.528
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.528
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.527
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.527
4erwSTUCyclin-dependent kinase 22.7.11.220.525
3a62STURibosomal protein S6 kinase beta-12.7.11.10.523
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.522
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.522
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.522
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.522
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.521
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.519
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.519
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.518
2x1nX1NCyclin-dependent kinase 22.7.11.220.518
3zep1NXTyrosine-protein kinase JAK32.7.10.20.518
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.518
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.517
1xjdSTUProtein kinase C theta type2.7.11.130.516
1zrzBI1Protein kinase C iota type2.7.11.130.516
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.515
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.514
4fv6E57Mitogen-activated protein kinase 12.7.11.240.514
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.513
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.512
4jqeANPCasein kinase II subunit alpha2.7.11.10.512
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.511
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.510
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.510
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.510
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.508
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.508
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.508
3sheI85MAP kinase-activated protein kinase 32.7.11.10.508
2cchATPCyclin-dependent kinase 22.7.11.220.507
2wpa889Cyclin-dependent kinase 22.7.11.220.507
4qmzB49Serine/threonine-protein kinase 242.7.11.10.507
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.506
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.506
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.506
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.506
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.505
2uzbC75Cyclin-dependent kinase 22.7.11.220.505
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.504
1aq1STUCyclin-dependent kinase 22.7.11.220.503
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.503
3t8oATPRhodopsin kinase/0.503
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.503
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.501
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.501
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.500
3i60E86Mitogen-activated protein kinase 12.7.11.240.500
4gmy0X5Tyrosine-protein kinase JAK2/0.500
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.499
4fkv61KCyclin-dependent kinase 22.7.11.220.499
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.498
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.498
3rkb12ZCyclin-dependent kinase 22.7.11.220.498
4fkr45KCyclin-dependent kinase 22.7.11.220.498
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.498
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.498
1pkdUCNCyclin-dependent kinase 22.7.11.220.497
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.497
3gu6ADPDeath-associated protein kinase 12.7.11.10.497
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.497
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.496
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.496
2c5nCK8Cyclin-dependent kinase 22.7.11.220.496
2wxvWXVCyclin-dependent kinase 22.7.11.220.495
3c4xATPRhodopsin kinase/0.494
4hvh19RTyrosine-protein kinase JAK32.7.10.20.494
4jia1K3Tyrosine-protein kinase JAK2/0.494
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.494
2vd5BI8Myotonin-protein kinase2.7.11.10.493
2b7aIZATyrosine-protein kinase JAK2/0.492
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.492
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.492
4fv9E71Mitogen-activated protein kinase 12.7.11.240.492
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.491
3zdu38RCyclin-dependent kinase-like 32.7.11.220.491
1e9hINRCyclin-dependent kinase 22.7.11.220.490
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.490
3rni21ZCyclin-dependent kinase 22.7.11.220.490
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.490
4gu610NFocal adhesion kinase 12.7.10.20.490
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.490
2uzlC94Cyclin-dependent kinase 22.7.11.220.489
3qxpX64Cyclin-dependent kinase 22.7.11.220.489
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.489
4ivd15TTyrosine-protein kinase JAK1/0.489
4qnaX11Serine/threonine-protein kinase 242.7.11.10.489
2j0m4STFocal adhesion kinase 12.7.10.20.488
3eyhIZATyrosine-protein kinase JAK1/0.488
4qmySTUSerine/threonine-protein kinase 242.7.11.10.488
3gu7ADPDeath-associated protein kinase 12.7.11.10.487
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.487
1gih1PUCyclin-dependent kinase 22.7.11.220.486
2vgoAD5Aurora kinase B-A2.7.11.10.486
2xikJ60Serine/threonine-protein kinase 252.7.11.10.486
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
4bgg844Activin receptor type-12.7.11.300.486
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.486
4fx360KCyclin-dependent kinase 22.7.11.220.486
5auwQUEDeath-associated protein kinase 12.7.11.10.486
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.485
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.485
2in6839Wee1-like protein kinase2.7.10.20.485
5e8wSTUTGF-beta receptor type-12.7.11.300.485
2j9mPY8Cyclin-dependent kinase 22.7.11.220.484
3bqr4RBDeath-associated protein kinase 3/0.484
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.484
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.484
4yuqKS1Calmodulin-like domain protein kinase/0.484
1oiyN41Cyclin-dependent kinase 22.7.11.220.483
1wvxBD4Death-associated protein kinase 12.7.11.10.483
3my5RFZCyclin-dependent kinase 22.7.11.220.483
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.483
3rk507ZCyclin-dependent kinase 22.7.11.220.483
4fkw62KCyclin-dependent kinase 22.7.11.220.483
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.483
5e92ANPTGF-beta receptor type-22.7.11.300.483
2j0lANPFocal adhesion kinase 12.7.10.20.482
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.482
3r9dX6BCyclin-dependent kinase 22.7.11.220.482
3tnwF18Cyclin-dependent kinase 22.7.11.220.482
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.482
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.482
1bygSTUTyrosine-protein kinase CSK/0.481
1g5sI17Cyclin-dependent kinase 22.7.11.220.481
1oguST8Cyclin-dependent kinase 22.7.11.220.481
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.481
2iw84SPCyclin-dependent kinase 22.7.11.220.481
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.481
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.481
3zewSTUEphrin type-B receptor 42.7.10.10.481
4acm7YGCyclin-dependent kinase 22.7.11.220.481
4bgh3I6Cyclin-dependent kinase 22.7.11.220.481
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.481
5auxKMPDeath-associated protein kinase 12.7.11.10.481
5av2KMPDeath-associated protein kinase 12.7.11.10.481
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.480
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.480
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.480
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.479
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.479
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.479
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.479
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.479
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.479
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.478
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.478
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.478
4j97ACPFibroblast growth factor receptor 2/0.478
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.477
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.477
4brxKGWFocal adhesion kinase 12.7.10.20.477
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.477
1fvv107Cyclin-dependent kinase 22.7.11.220.476
2vv9IM9Cyclin-dependent kinase 22.7.11.220.476
3ztxZTXAurora kinase B-A2.7.11.10.476
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.476
4gk2L66Ephrin type-A receptor 32.7.10.10.476
4wboANWRhodopsin kinase/0.476
2bkzSBCCyclin-dependent kinase 22.7.11.220.475
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.475
3pe2E1BCasein kinase II subunit alpha2.7.11.10.475
3rk708ZCyclin-dependent kinase 22.7.11.220.475
4eor4SPCyclin-dependent kinase 22.7.11.220.475
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.475
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.475
4fv8E63Mitogen-activated protein kinase 12.7.11.240.475
5auvAGIDeath-associated protein kinase 12.7.11.10.475
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.474
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.474
4ek610KCyclin-dependent kinase 22.7.11.220.474
4ivb1J5Tyrosine-protein kinase JAK1/0.474
1oitHDTCyclin-dependent kinase 22.7.11.220.473
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.473
3bi6396Wee1-like protein kinase2.7.10.20.473
4eomATPCyclin-dependent kinase 22.7.11.220.473
4ivc1J6Tyrosine-protein kinase JAK1/0.473
1gij2PUCyclin-dependent kinase 22.7.11.220.472
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.472
1yvj4STTyrosine-protein kinase JAK32.7.10.20.472
2bheBRYCyclin-dependent kinase 22.7.11.220.472
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.472
3raiX85Cyclin-dependent kinase 22.7.11.220.472
3ral04ZCyclin-dependent kinase 22.7.11.220.472
2j0k4STFocal adhesion kinase 12.7.10.20.471
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.471
3rak03ZCyclin-dependent kinase 22.7.11.220.471
1pxpCK8Cyclin-dependent kinase 22.7.11.220.470
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.470
1w0xOLOCyclin-dependent kinase 22.7.11.220.470
2acxANPG protein-coupled receptor kinase 62.7.11.160.470
2izt23DCasein kinase I isoform gamma-32.7.11.10.470
2wipP49Cyclin-dependent kinase 22.7.11.220.470
2z2w770Wee1-like protein kinase2.7.10.20.470
4bcnT9NCyclin-dependent kinase 22.7.11.220.470
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.470
1fvt106Cyclin-dependent kinase 22.7.11.220.469
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.469
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.469
2j0j4STFocal adhesion kinase 12.7.10.20.469
2wihP48Cyclin-dependent kinase 22.7.11.220.469
2xneASHAurora kinase A2.7.11.10.469
3cr0809Wee1-like protein kinase2.7.10.20.469
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.469
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.469
4ek816KCyclin-dependent kinase 22.7.11.220.469
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.469
4l9i8PRRhodopsin kinase/0.469
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.469
4y93746Tyrosine-protein kinase/0.469
5e8xSTUTGF-beta receptor type-12.7.11.300.469
1pyePM1Cyclin-dependent kinase 22.7.11.220.468
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.468
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.468
1ykr628Cyclin-dependent kinase 22.7.11.220.468
2ckeIQUDeath-associated protein kinase 2/0.468
2jkkBI9Focal adhesion kinase 12.7.10.20.468
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.468
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.468
4gk3L87Ephrin type-A receptor 32.7.10.10.468
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.468
5av047XDeath-associated protein kinase 12.7.11.10.468
3dfcANPDeath-associated protein kinase 12.7.11.10.467
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.467
3qtxX43Cyclin-dependent kinase 22.7.11.220.467
3rpv26ZCyclin-dependent kinase 22.7.11.220.467
3uli1N3Cyclin-dependent kinase 22.7.11.220.467
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.467
4e4m0NHTyrosine-protein kinase JAK2/0.467
4qo9627Serine/threonine-protein kinase 242.7.11.10.467
5av3KMPDeath-associated protein kinase 12.7.11.10.467
1unlRRCCyclin-dependent-like kinase 52.7.11.10.466
2hckQUETyrosine-protein kinase HCK2.7.10.20.466
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.466
2xyuQ9GEphrin type-A receptor 42.7.10.10.466
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.466
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.466
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.466
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.466
2qo9ANPEphrin type-A receptor 32.7.10.10.465
2w06FRVCyclin-dependent kinase 22.7.11.220.465
2yn8STUEphrin type-B receptor 42.7.10.10.465
3c4wATPRhodopsin kinase/0.465
3iok1P6Tyrosine-protein kinase JAK2/0.465
1u54ACPActivated CDC42 kinase 1/0.464
2c6tDT5Cyclin-dependent kinase 22.7.11.220.464
2w1hL0FCyclin-dependent kinase 22.7.11.220.464
3ggfGVDSerine/threonine-protein kinase 26/0.464
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.464
3rjc06ZCyclin-dependent kinase 22.7.11.220.464
4bcmT7ZCyclin-dependent kinase 22.7.11.220.464
4bcqTJFCyclin-dependent kinase 22.7.11.220.464
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.464
2znnS44Peroxisome proliferator-activated receptor alpha/0.463
3flwFLWMitogen-activated protein kinase 14/0.463
3mtfA3FActivin receptor type-12.7.11.300.463
3qwkX62Cyclin-dependent kinase 22.7.11.220.463
3zmmF9JTyrosine-protein kinase JAK2/0.463
4c62XWWTyrosine-protein kinase JAK2/0.463
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.463
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.463
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.462
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.462
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.462
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.462
3eb0DRKUncharacterized protein/0.462
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.462
3r8lZ30Cyclin-dependent kinase 22.7.11.220.462
4fko20KCyclin-dependent kinase 22.7.11.220.462
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.462
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.462
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.462
1finATPCyclin-dependent kinase 22.7.11.220.461
2eufLQQCyclin-dependent kinase 62.7.11.220.461
2w05FRTCyclin-dependent kinase 22.7.11.220.461
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.461
3qtqX35Cyclin-dependent kinase 22.7.11.220.461
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.461
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.461
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.461
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.461
4wsqKSAAP2-associated protein kinase 12.7.11.10.461
5dt0SKEAurora kinase A2.7.11.10.461
2jkqVG8Focal adhesion kinase 12.7.10.20.460
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.460
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.460
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.460
5dr6SKEAurora kinase A2.7.11.10.460
1h1pCMGCyclin-dependent kinase 22.7.11.220.459
1h1s4SPCyclin-dependent kinase 22.7.11.220.459
1ke5LS1Cyclin-dependent kinase 22.7.11.220.459
2c6iDT1Cyclin-dependent kinase 22.7.11.220.459
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.459
2yaaATPDeath-associated protein kinase 2/0.459
3at4CCKCasein kinase II subunit alpha2.7.11.10.459
3ddpRC8Cyclin-dependent kinase 22.7.11.220.459
3gu5ANPDeath-associated protein kinase 12.7.11.10.459
3pj8404Cyclin-dependent kinase 22.7.11.220.459
3py0SU9Cyclin-dependent kinase 22.7.11.220.459
3r1qX75Cyclin-dependent kinase 22.7.11.220.459
3r7iX9ICyclin-dependent kinase 22.7.11.220.459
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.459
4hvi19STyrosine-protein kinase JAK32.7.10.20.459
1pxmCK5Cyclin-dependent kinase 22.7.11.220.458
2bfyH1NAurora kinase B-A2.7.11.10.458
2c6dANPAurora kinase A2.7.11.10.458
2yac937Serine/threonine-protein kinase PLK12.7.11.210.458
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.458
3r9hZ67Cyclin-dependent kinase 22.7.11.220.458
4hge15VTyrosine-protein kinase JAK2/0.458
4k771Q4Tyrosine-protein kinase JAK1/0.458
5dr9SKEAurora kinase A2.7.11.10.458
1eh4IC1Casein kinase I homolog 12.7.11.10.457
1urwI1PCyclin-dependent kinase 22.7.11.220.457
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2vwz7X6Ephrin type-B receptor 42.7.10.10.457
2x6dX6DAurora kinase A2.7.11.10.457
2xb7GUIALK tyrosine kinase receptor2.7.10.10.457
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.457
3ti1B49Cyclin-dependent kinase 22.7.11.220.457
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.457
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4eok4SPCyclin-dependent kinase 22.7.11.220.457
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.457
1gii1PUCyclin-dependent kinase 22.7.11.220.456
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.456
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.456
2r3lSCWCyclin-dependent kinase 22.7.11.220.456
2uzdC85Cyclin-dependent kinase 22.7.11.220.456
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.456
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.456
3qu0X40Cyclin-dependent kinase 22.7.11.220.456
3r9oZ71Cyclin-dependent kinase 22.7.11.220.456
4a9rRU5Serine/threonine-protein kinase Chk22.7.11.10.456
4btjATPTau-tubulin kinase 12.7.11.10.456
1oecAA2Fibroblast growth factor receptor 2/0.455
1oiuN76Cyclin-dependent kinase 22.7.11.220.455
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.455
1u3cFADCryptochrome-1/0.455
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.455
2b52D42Cyclin-dependent kinase 22.7.11.220.455
2c5yMTWCyclin-dependent kinase 22.7.11.220.455
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.455
2w17I19Cyclin-dependent kinase 22.7.11.220.455
3a7hATPSerine/threonine-protein kinase 242.7.11.10.455
3bhtMFRCyclin-dependent kinase 22.7.11.220.455
3biz61EWee1-like protein kinase2.7.10.20.455
3dogNNNCyclin-dependent kinase 22.7.11.220.455
3lctADPALK tyrosine kinase receptor2.7.10.10.455
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.455
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.455
4fks46KCyclin-dependent kinase 22.7.11.220.455
4i22IREEpidermal growth factor receptor2.7.10.10.455
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.455
1bwsNDPGDP-L-fucose synthase/0.454
1u3dFADCryptochrome-1/0.454
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.454
2bhhRYUCyclin-dependent kinase 22.7.11.220.454
2dwbANPAurora kinase A2.7.11.10.454
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.454
2wotZZGTGF-beta receptor type-12.7.11.300.454
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.454
3ezvEZVCyclin-dependent kinase 22.7.11.220.454
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.454
3nynSGVG protein-coupled receptor kinase 62.7.11.160.454
3sqq99ZCyclin-dependent kinase 22.7.11.220.454
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.454
4dgnLU2Casein kinase II subunit alpha2.7.11.10.454
4qmlANPSerine/threonine-protein kinase 242.7.11.10.454
1vjy460TGF-beta receptor type-12.7.11.300.453
1y91CT9Cyclin-dependent kinase 22.7.11.220.453
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.453
2vx17X8Ephrin type-B receptor 42.7.10.10.453
4ambDUDPutative glycosyl transferase/0.453
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.453
4iva1J5Tyrosine-protein kinase JAK2/0.453
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.453
4nka2K7Fibroblast growth factor receptor 1/0.453
2c4g514Cyclin-dependent kinase 22.7.11.220.452
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.452
2uzeC95Cyclin-dependent kinase 22.7.11.220.452
2xa4AZ5Tyrosine-protein kinase JAK2/0.452
3gu83GUDeath-associated protein kinase 12.7.11.10.452
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.452
3rk909ZCyclin-dependent kinase 22.7.11.220.452
3s0o50ZCyclin-dependent kinase 22.7.11.220.452
3vf80JETyrosine-protein kinase SYK2.7.10.20.452
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.452
4c61LMMTyrosine-protein kinase JAK2/0.452
1h1r6CPCyclin-dependent kinase 22.7.11.220.451
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.451
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.451
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2h96893Mitogen-activated protein kinase 82.7.11.240.451
2of4979Tyrosine-protein kinase Lck2.7.10.20.451
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.451
2xmyCDKCyclin-dependent kinase 22.7.11.220.451
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.451
4g2fC07Ephrin type-A receptor 32.7.10.10.451
1oi9N20Cyclin-dependent kinase 22.7.11.220.450
1wvySTUDeath-associated protein kinase 12.7.11.10.450
2pywADPMethylthioribose kinase2.7.1.1000.450
2zdt46CMitogen-activated protein kinase 102.7.11.240.450
3a1eACPProbable copper-exporting P-type ATPase A3.6.3.540.450
3lfqA28Cyclin-dependent kinase 22.7.11.220.450
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.450
3pxkPXKFocal adhesion kinase 12.7.10.20.450
3rvg17PTyrosine-protein kinase JAK2/0.450
3wblPDYCyclin-dependent kinase 22.7.11.220.450
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.450
4ei40Q2Tyrosine-protein kinase JAK1/0.450
4gg70J8Hepatocyte growth factor receptor2.7.10.10.450
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.450
4ysjADPCalmodulin-like domain protein kinase/0.450
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.450
3emg685Tyrosine-protein kinase SYK2.7.10.20.449
3hx4ANPCalmodulin-domain protein kinase 1/0.449
3q5iANPProtein kinase, putative/0.449
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.449
3r73X87Cyclin-dependent kinase 22.7.11.220.449
3rmf20ZCyclin-dependent kinase 22.7.11.220.449
3s2pPMUCyclin-dependent kinase 22.7.11.220.449
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.449
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.449
1pxlCK4Cyclin-dependent kinase 22.7.11.220.448
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.448
2izrBRKCasein kinase I isoform gamma-32.7.11.10.448
2pvnP63Casein kinase II subunit alpha2.7.11.10.448
2pym1UNGag-Pol polyprotein3.4.23.160.448
2vx07X7Ephrin type-B receptor 42.7.10.10.448
2x4f16XMyosin light chain kinase family member 42.7.11.10.448
2xnbY8LCyclin-dependent kinase 22.7.11.220.448
3s1h56ZCyclin-dependent kinase 22.7.11.220.448
3sw418KCyclin-dependent kinase 22.7.11.220.448
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.448
4e200MYNon-receptor tyrosine-protein kinase TYK22.7.10.20.448
4iwd1JCHepatocyte growth factor receptor2.7.10.10.448
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.448
4o0wADNAurora kinase A2.7.11.10.448
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.448
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.447
3qtrX36Cyclin-dependent kinase 22.7.11.220.447
4e6d0NUTyrosine-protein kinase JAK2/0.447
4fkt48KCyclin-dependent kinase 22.7.11.220.447
4grb0XGCasein kinase II subunit alpha2.7.11.10.447
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.447
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.447
1di8DTQCyclin-dependent kinase 22.7.11.220.446
1ol5ADPAurora kinase A2.7.11.10.446
1xddAAYIntegrin alpha-L/0.446
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.446
3a3gDLZLumazine protein/0.446
3bhy7CPDeath-associated protein kinase 3/0.446
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.446
3r6xX84Cyclin-dependent kinase 22.7.11.220.446
4dgo0JWCasein kinase II subunit alpha2.7.11.10.446
5e8ySTUTGF-beta receptor type-22.7.11.300.446
5f8eSAHPossible transcriptional regulatory protein/0.446
1k6cMK1Gag-Pol polyprotein3.4.23.160.445
1ke6LS2Cyclin-dependent kinase 22.7.11.220.445
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.445
1v0oINRCell division control protein 2 homolog2.7.11.220.445
2fvdLIACyclin-dependent kinase 22.7.11.220.445
2x9fX9FEphrin type-B receptor 42.7.10.10.445
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.445
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.445
3ibqATPPyridoxal kinase/0.445
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.445
3rm719ZCyclin-dependent kinase 22.7.11.220.445
4f081RSTyrosine-protein kinase JAK2/0.445
4fob0USALK tyrosine kinase receptor2.7.10.10.445
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.445
1lf3EH5Plasmepsin-23.4.23.390.444
1oirHDYCyclin-dependent kinase 22.7.11.220.444
2f2cAP9Cyclin-dependent kinase 62.7.11.220.444
2ijmADPFocal adhesion kinase 12.7.10.20.444
2py3ACPFibroblast growth factor receptor 2/0.444
2y6o1N1Ephrin type-A receptor 42.7.10.10.444
3du8553Glycogen synthase kinase-3 beta2.7.11.260.444
3lfnA27Cyclin-dependent kinase 22.7.11.220.444
3nieANPMitogen-activated protein kinase/0.444
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.444
3sw719KCyclin-dependent kinase 22.7.11.220.444
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.444
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.444
4eoi1ROCyclin-dependent kinase 22.7.11.220.444
4fod0UVALK tyrosine kinase receptor2.7.10.10.444
4gk4L90Ephrin type-A receptor 32.7.10.10.444
4lopSB4Mitogen-activated protein kinase 14/0.444
1bxoPP7Penicillopepsin-13.4.23.200.443
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.443
1vyzN5BCyclin-dependent kinase 22.7.11.220.443
2b53D23Cyclin-dependent kinase 22.7.11.220.443
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.443
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.443
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.443
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3r8vZ62Cyclin-dependent kinase 22.7.11.220.443
3sfeFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.443
4aqc88ATyrosine-protein kinase JAK2/0.443
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.443
4f640S8Fibroblast growth factor receptor 1/0.443
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.443
3sn6P0GBeta-2 adrenergic receptor/0.443
1kfbIGPTryptophan synthase alpha chain/0.442
2etm7PYFocal adhesion kinase 12.7.10.20.442
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
3ddqRRCCyclin-dependent kinase 22.7.11.220.442
3h3r14HCollagen type IV alpha-3-binding protein/0.442
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.442
3qc9ADPRhodopsin kinase/0.442
4a6nFADTetX family tetracycline inactivation enzyme/0.442
4ji91M3Tyrosine-protein kinase JAK2/0.442
5dt3ATPAurora kinase A2.7.11.10.442
1ke7LS3Cyclin-dependent kinase 22.7.11.220.441
2j4z626Aurora kinase A2.7.11.10.441
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.441
3w18N13Aurora kinase A2.7.11.10.441
4aguD15Cyclin-dependent kinase-like 1/0.441
4d4sBI9Focal adhesion kinase 12.7.10.20.441
4ehzJAKTyrosine-protein kinase JAK1/0.441
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.441
4hvg19QTyrosine-protein kinase JAK32.7.10.20.441
4loqSB4Mitogen-activated protein kinase 14/0.441
5dt4ATPAurora kinase A2.7.11.10.441
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.441
1k6pXN3Gag-Pol polyprotein3.4.23.160.440
1ke9LS5Cyclin-dependent kinase 22.7.11.220.440
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.440
2r3jSCJCyclin-dependent kinase 22.7.11.220.440
3bbrBHYGlutamate receptor 2/0.440
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.440
3qqlX03Cyclin-dependent kinase 22.7.11.220.440
4fyn0VETyrosine-protein kinase SYK2.7.10.20.440
4fz60VGTyrosine-protein kinase SYK2.7.10.20.440