Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ft4 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4ft4 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 1.000 | |
| 1skm | SAH | Modification methylase HhaI | 2.1.1.37 | 0.512 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.502 | |
| 3mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.495 | |
| 1fjx | SAH | Modification methylase HhaI | 2.1.1.37 | 0.494 | |
| 1mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.489 | |
| 2hmy | SAM | Modification methylase HhaI | 2.1.1.37 | 0.484 | |
| 2i9k | SAH | Modification methylase HhaI | 2.1.1.37 | 0.477 | |
| 9mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.474 | |
| 2uyh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.465 | |
| 4wxx | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.456 | |
| 5mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.456 | |
| 10mh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.453 | |
| 8mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.449 | |
| 2zcj | SAH | Modification methylase HhaI | 2.1.1.37 | 0.448 | |
| 2z6u | SAH | Modification methylase HhaI | 2.1.1.37 | 0.447 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.445 | |
| 3pt9 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.440 |