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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4fsa0V3Queuine tRNA-ribosyltransferase2.4.2.29

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4fsa0V3Queuine tRNA-ribosyltransferase2.4.2.291.000
1y5wNEZQueuine tRNA-ribosyltransferase2.4.2.290.577
4gkt0O1Queuine tRNA-ribosyltransferase2.4.2.290.572
4gg90WWQueuine tRNA-ribosyltransferase2.4.2.290.538
3ge7AFQQueuine tRNA-ribosyltransferase2.4.2.290.534
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.517
4hshQEIQueuine tRNA-ribosyltransferase2.4.2.290.501
4fps0UXQueuine tRNA-ribosyltransferase2.4.2.290.490
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.486
4fr10V2Queuine tRNA-ribosyltransferase2.4.2.290.486
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.290.463
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.458
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.456
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.452
1f3eDPZQueuine tRNA-ribosyltransferase2.4.2.290.444
1r5yDQUQueuine tRNA-ribosyltransferase2.4.2.290.444
4giy0WYQueuine tRNA-ribosyltransferase2.4.2.290.441