Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4fj5DTPDNA-directed DNA polymerase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4fj5DTPDNA-directed DNA polymerase/1.000
4dtjTTPDNA-directed DNA polymerase/0.841
4fjjTTPDNA-directed DNA polymerase/0.811
4dtmDCPDNA-directed DNA polymerase/0.756
3ne6DCPDNA-directed DNA polymerase/0.689
4fjlDGTDNA-directed DNA polymerase/0.688
3supDCPDNA-directed DNA polymerase/0.677
4m3tATPDNA-directed DNA polymerase/0.656
4m3xATPDNA-directed DNA polymerase/0.653
4dtpDGTDNA-directed DNA polymerase/0.642
4dtoDCPDNA-directed DNA polymerase/0.635
4fk4DGTDNA-directed DNA polymerase/0.624
4m42ATPDNA-directed DNA polymerase/0.613
4fjmDCPDNA-directed DNA polymerase/0.611
3lzjCTPDNA-directed DNA polymerase/0.596
4khyTTPDNA-directed DNA polymerase/0.593
4dtxTTPDNA-directed DNA polymerase/0.591
4ptfDCPDNA polymerase epsilon catalytic subunit A2.7.7.70.496