sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4f1q | 0RZ | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4f1q | 0RZ | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 1.000 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.592 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.568 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.558 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.557 | |
| 4l6s | 1WQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.554 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.551 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.537 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.537 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.536 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.534 | |
| 3c4h | DRL | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.532 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.527 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.524 | |
| 2rcw | AAI | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.522 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.522 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.521 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.520 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.520 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.518 | |
| 4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.518 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.510 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.509 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.508 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.508 | |
| 1uk0 | FRM | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.506 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.506 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.502 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.502 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.500 | |
| 5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.500 | |
| 1thz | 326 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.498 | |
| 2g6p | HM2 | Methionine aminopeptidase 1 | / | 0.498 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.494 | |
| 1typ | NAP | Trypanothione reductase | 1.8.1.12 | 0.494 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.493 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.492 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.492 | |
| 1azl | FMN | Flavodoxin | / | 0.491 | |
| 4hlm | 16S | Tankyrase-2 | 2.4.2.30 | 0.491 | |
| 4kdr | SAH | Ubiquinone biosynthesis O-methyltransferase | / | 0.490 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.489 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.489 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.488 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.487 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.487 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.486 | |
| 3c1o | NAP | Eugenol synthase | / | 0.485 | |
| 4kxj | P34 | Nucleoprotein | / | 0.485 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.484 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.484 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.483 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.483 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.483 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.482 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.482 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.482 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.482 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.482 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 1zm4 | TAD | Exotoxin A | 2.4.2.36 | 0.481 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.481 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.481 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.479 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.479 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.479 | |
| 1pw1 | HEL | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.478 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.478 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.478 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.478 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 1fxv | PNN | Penicillin G acylase | 3.5.1.11 | 0.477 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.476 | |
| 2rd6 | 78P | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.476 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.476 | |
| 2gmu | PDG | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.475 | |
| 2po3 | T4K | 4-dehydrase | / | 0.475 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.475 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.475 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.475 | |
| 1dmw | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.474 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.474 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.473 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.473 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.473 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.473 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.472 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.472 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.472 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.472 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.471 | |
| 2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.471 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.471 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.471 | |
| 4daj | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.470 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.469 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.469 | |
| 1uk1 | FRQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.469 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.469 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.469 | |
| 2mt9 | FMN | Flavodoxin 2 | / | 0.469 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.469 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.469 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.469 | |
| 3rl4 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.469 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.469 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.469 | |
| 4bs4 | A64 | Tankyrase-2 | 2.4.2.30 | 0.469 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.468 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.468 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.468 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.468 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.468 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.468 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.468 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.468 | |
| 4l0t | 1V0 | Tankyrase-2 | 2.4.2.30 | 0.468 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
| 2c97 | JCL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.467 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.467 | |
| 3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.467 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.466 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.466 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.466 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.466 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.466 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.466 | |
| 4ckc | SAH | mRNA-capping enzyme catalytic subunit | 2.1.1.56 | 0.466 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.466 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 2gg9 | U16 | Methionine aminopeptidase | / | 0.465 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.465 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.465 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.465 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.465 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.465 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.464 | |
| 1lrm | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.464 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.464 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.464 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.464 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.464 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.464 | |
| 3vc2 | SAH | Geranyl diphosphate 2-C-methyltransferase | 2.1.1.255 | 0.464 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.464 | |
| 1fnb | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.463 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.463 | |
| 3cvk | N34 | Genome polyprotein | 2.7.7.48 | 0.463 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.463 | |
| 3nhp | HGZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.463 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.463 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.463 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.463 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.463 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1xk9 | P34 | Exotoxin A | 2.4.2.36 | 0.462 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 2c2b | SAM | Threonine synthase 1, chloroplastic | 4.2.3.1 | 0.462 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.462 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.462 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.462 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.462 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.462 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.462 | |
| 1c7o | PPG | Hemolysin | / | 0.461 | |
| 1sm4 | FAD | Ferredoxin--NADP reductase | / | 0.461 | |
| 1yun | ATP | Probable nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.461 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.461 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.461 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.461 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.461 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.461 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.461 | |
| 4qen | SAH | Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4 | 2.1.1.43 | 0.461 | |
| 4wbd | ADP | Putative cysteine ligase BshC | / | 0.461 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.461 | |
| 1e64 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.460 | |
| 1g6o | ADP | Cag alpha | / | 0.460 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.460 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.460 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.460 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.460 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.460 | |
| 2tsr | UMP | Thymidylate synthase | 2.1.1.45 | 0.460 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3ksl | SZH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.460 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.460 | |
| 4a99 | MIY | TetX family tetracycline inactivation enzyme | / | 0.460 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.460 | |
| 5agk | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.460 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 1wl4 | COA | Acetyl-CoA acetyltransferase, cytosolic | 2.3.1.9 | 0.459 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.459 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.459 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.459 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.459 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.459 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.459 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.459 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1que | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.458 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.458 | |
| 3qvi | K95 | HAP protein | / | 0.458 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.458 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.458 | |
| 4bvn | P32 | Beta-1 adrenergic receptor | / | 0.458 | |
| 4h6p | FMN | Chromate reductase | / | 0.458 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4isf | 1FX | Glucokinase | 2.7.1.2 | 0.458 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.458 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.458 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.458 | |
| 4xwt | U5P | Ribonuclease J | / | 0.458 | |
| 1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.457 | |
| 1rxj | BNI | Streptavidin | / | 0.457 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.457 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.457 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.457 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 3zpq | XF5 | Beta-1 adrenergic receptor | / | 0.457 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.457 | |
| 4hej | 14D | Thymidylate kinase | / | 0.457 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.457 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.456 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.456 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.456 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.456 | |
| 3ha3 | SAH | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.456 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.456 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.456 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.456 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.456 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.455 | |
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.455 | |
| 2ejz | SAH | Diphthine synthase | / | 0.455 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.455 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.455 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.455 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.455 | |
| 4was | COO | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.455 | |
| 1aku | FMN | Flavodoxin | / | 0.454 | |
| 1fml | RTL | Retinol dehydratase | / | 0.454 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.454 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.454 | |
| 1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.454 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.454 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.454 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.454 | |
| 3keo | NAD | Redox-sensing transcriptional repressor Rex | / | 0.454 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4bup | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.454 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.454 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.454 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.453 | |
| 1xi2 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.453 | |
| 1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 0.453 | |
| 2gl0 | ADN | Uncharacterized protein | / | 0.453 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.453 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.453 | |
| 2r8o | T5X | Transketolase 1 | / | 0.453 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.453 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.453 | |
| 4hlh | 20D | Tankyrase-2 | 2.4.2.30 | 0.453 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
| 1dtp | APU | Diphtheria toxin | / | 0.452 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.452 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 2oli | IOP | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.452 | |
| 3er9 | 3AT | Poly(A) polymerase catalytic subunit | 2.7.7.19 | 0.452 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.452 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.452 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.452 | |
| 4b6l | 9ZP | Serine/threonine-protein kinase PLK3 | 2.7.11.21 | 0.452 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.452 | |
| 4qtn | NNR | Nicotinamide riboside transporter PnuC | / | 0.452 | |
| 4xp4 | COC | Sodium-dependent dopamine transporter | / | 0.452 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.452 | |
| 1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.451 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.451 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.451 | |
| 1u2r | SO1 | Elongation factor 2 | / | 0.451 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.451 | |
| 2ycw | CAU | Beta-1 adrenergic receptor | / | 0.451 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 3gam | MXX | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.451 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.451 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.451 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 5c80 | URI | Uridine phosphorylase | / | 0.451 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.450 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.450 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.450 | |
| 1z5u | CMP | Class B acid phosphatase | / | 0.450 | |
| 2e20 | B4P | Propionate kinase | / | 0.450 | |
| 2rc6 | FAD | Ferredoxin--NADP reductase | / | 0.450 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.450 | |
| 2x3j | ATP | AcsD | / | 0.450 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.450 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.450 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3owx | XRA | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.450 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.450 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.450 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.450 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.450 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.450 | |
| 4qak | 2AM | RNA 2',3'-cyclic phosphodiesterase | / | 0.450 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.450 | |
| 4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.450 | |
| 5erm | 210 | Fusicoccadiene synthase | 4.2.3.43 | 0.450 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.450 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.450 | |
| 5f8u | P32 | Beta-1 adrenergic receptor | / | 0.450 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.449 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.449 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.449 | |
| 1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.449 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 1wdk | ACO | 3-ketoacyl-CoA thiolase | / | 0.449 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.449 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.449 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2y03 | 5FW | Beta-1 adrenergic receptor | / | 0.449 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3arv | SAU | Chitinase A | / | 0.449 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.449 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.449 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.449 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.449 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.449 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.449 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 4iue | AJ4 | Tankyrase-2 | 2.4.2.30 | 0.449 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.449 | |
| 4phl | PIL | Phosphodiesterase | / | 0.449 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.449 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.448 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.448 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.448 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.448 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.448 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 2pid | YSA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.448 | |
| 2w02 | ATP | AcsD | / | 0.448 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.448 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.448 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.448 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.448 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4bux | F35 | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 4dyn | 0MR | Nucleoprotein | / | 0.448 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.448 | |
| 4fox | UMP | Thymidylate synthase ThyA | / | 0.448 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.448 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.448 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.447 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.447 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3frk | TQP | QdtB | / | 0.447 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.447 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.447 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.447 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.447 | |
| 4amj | CVD | Beta-1 adrenergic receptor | / | 0.447 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.447 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4bek | XK0 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4bz8 | J38 | Histone deacetylase | / | 0.447 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 4f3g | KAI | Glutamate receptor 3 | / | 0.447 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.447 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.447 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 4kzl | 20D | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.447 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.447 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.447 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.446 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.446 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.446 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.446 | |
| 2vbv | FMN | Riboflavin kinase | 2.7.1.161 | 0.446 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.446 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 3clx | X22 | E3 ubiquitin-protein ligase XIAP | 6.3.2 | 0.446 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3nt5 | NAI | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.446 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 1gaw | FAD | Ferredoxin | / | 0.445 | |
| 1j9g | FMN | Flavodoxin | / | 0.445 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1lke | DOG | Bilin-binding protein | / | 0.445 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.445 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.445 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.445 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.445 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.445 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.445 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 4bvh | OCZ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.445 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.445 | |
| 4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4lut | DCS | Alanine racemase | / | 0.445 | |
| 4lxl | PD2 | Lysine-specific demethylase 4B | 1.14.11 | 0.445 | |
| 4msk | 2C8 | Tankyrase-1 | 2.4.2.30 | 0.445 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.445 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.445 | |
| 4to4 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 5doz | NDP | JamJ | / | 0.445 | |
| 2y04 | 68H | Beta-1 adrenergic receptor | / | 0.445 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.445 | |
| 1bx0 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.444 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.444 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1fnd | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.444 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.444 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.444 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1w87 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.444 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.444 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3hdq | GDU | UDP-galactopyranose mutase | / | 0.444 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.444 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.444 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.444 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 4iks | TFD | Methionine aminopeptidase 1 | / | 0.444 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.444 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.444 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.444 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.443 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.443 | |
| 1pl1 | ABY | Glutathione S-transferase A1 | 2.5.1.18 | 0.443 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.443 | |
| 2ed4 | FAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.443 | |
| 2ohh | FMN | Type A flavoprotein FprA | 1 | 0.443 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 2z4z | SC0 | Geranylgeranyl pyrophosphate synthase | / | 0.443 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3af4 | GCP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3c74 | ANU | Uridine phosphorylase | 2.4.2.3 | 0.443 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.443 | |
| 3m53 | SAH | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.443 | |
| 3n61 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 3nhk | VAP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.443 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 3zxi | TYA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.443 | |
| 4afh | L0B | Achbp | / | 0.443 | |
| 4da5 | 0H7 | Choline kinase alpha | 2.7.1.32 | 0.443 | |
| 4hmh | F94 | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 4nbj | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.443 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.443 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.443 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.443 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.443 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1vfs | DCS | Alanine racemase | / | 0.442 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.442 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2qe2 | 452 | Polyprotein | / | 0.442 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.442 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 2xvv | 9DN | Serum albumin | / | 0.442 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.442 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.442 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.442 | |
| 3irh | DTP | HD domain protein | / | 0.442 | |
| 3jt6 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3tpr | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3wth | IM4 | Acetylcholine-binding protein | / | 0.442 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.442 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.442 | |
| 4djx | 0KQ | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.442 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.442 | |
| 5ex0 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.442 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.442 | |
| 1g7u | PEP | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.441 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.441 | |
| 1tg2 | H2B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.441 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.441 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.441 | |
| 2r8p | T6F | Transketolase 1 | / | 0.441 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.441 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.441 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.441 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.441 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.441 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.441 | |
| 4buw | F33 | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.441 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.441 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.441 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4l34 | 1VG | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.441 | |
| 4ydd | MGD | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.441 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.441 | |
| 1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.440 | |
| 1fnc | FDA | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.440 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.440 | |
| 1ux0 | THU | Cytidine deaminase | 3.5.4.5 | 0.440 | |
| 1vp5 | NAP | Oxidoreductase, aldo/keto reductase family | / | 0.440 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.440 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.440 | |
| 2dsg | SAH | Diphthine synthase | / | 0.440 | |
| 2g7y | MO9 | Cathepsin S | 3.4.22.27 | 0.440 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.440 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2v57 | PRL | TetR family transcriptional regulator | / | 0.440 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.440 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.440 | |
| 3kr8 | XAV | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 3r96 | ACO | MccE protein | / | 0.440 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4k38 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.440 | |
| 4l32 | 1VF | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.440 | |
| 4nv1 | TYD | Formyl transferase | / | 0.440 | |
| 4qfx | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.440 | |
| 5fmm | MGT | Polymerase basic protein 2 | / | 0.440 |