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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4el9AFERibosomal protein S6 kinase alpha-32.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4el9AFERibosomal protein S6 kinase alpha-32.7.11.11.000
3ubdSL0Ribosomal protein S6 kinase alpha-32.7.11.10.706
4gueQCTRibosomal protein S6 kinase alpha-32.7.11.10.662
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.525
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.514
3reyXACAdenosine receptor A2a/0.513
3vt7VDXVitamin D3 receptor/0.507
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.506
5hs1VORLanosterol 14-alpha demethylase/0.504
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.503
4rbs0RVMetallo-beta-lactamase type 2/0.501
2agvTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.500
1x8lOXRRetinol dehydratase/0.499
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.499
4ia3BIVVitamin D3 receptor A/0.497
4ia7BIVVitamin D3 receptor A/0.497
5ab7MLCNonspecific lipid-transfer protein, putative/0.497
1ie8KH1Vitamin D3 receptor/0.494
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.494
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.494
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.492
2z3uCRRCytochrome P450/0.492
3ar7TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.492
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.492
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.492
2vcmM11Isopenicillin N synthase1.21.3.10.491
1xlsREARetinoic acid receptor RXR-alpha/0.490
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.490
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.489
2dqsTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.489
2oaxSNLMineralocorticoid receptor/0.489
2wo7ASVIsopenicillin N synthase1.21.3.10.489
3a1l2CCCytochrome P450/0.489
3rfmCFFAdenosine receptor A2a/0.489
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.488
4iaq2GM5-hydroxytryptamine receptor 1B/0.488
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.487
2hcdBIVVitamin D3 receptor A/0.487
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.487
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.487
4rh10TTSpore photoproduct lyase/0.486
3uzcT4EAdenosine receptor A2a/0.486
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.485
1obnASVIsopenicillin N synthase1.21.3.10.484
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.484
3p9tTCLRepressor/0.484
3vt9YI4Vitamin D3 receptor/0.484
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.484
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.483
2qk8MTXDihydrofolate reductase/0.483
3qlwN22Dihydrofolate reductase1.5.1.30.483
2ydwWSHBromodomain-containing protein 2/0.482
3bfb9ODPheromone-binding protein ASP1/0.482
3pwhZMAAdenosine receptor A2a/0.482
3uzaT4GAdenosine receptor A2a/0.482
1q5dEPBEpothilone C/D epoxidase1.140.481
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.481
2xkc4VQSerine/threonine-protein kinase Nek22.7.11.10.481
3d75NBBPheromone-binding protein ASP1/0.481
3nj0PYVAbscisic acid receptor PYL2/0.481
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.481
4h9753SDihydrofolate reductase1.5.1.30.481
4ia1BIVVitamin D3 receptor A/0.481
3bfa9ODOdorant binding protein ASP1/0.480
4nieNBHNuclear receptor ROR-gamma/0.480
1pkfEPDEpothilone C/D epoxidase1.140.479
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.479
3lu8IQXSerum albumin/0.479
3v94WYQPhosphodiesterase/0.479
4nmbFADBifunctional protein PutA/0.479
3p3zP3ZPutative cytochrome P450/0.478
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.478
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.478
2o4rVD5Vitamin D3 receptor/0.477
2p4iMR9Angiopoietin-1 receptor2.7.10.10.477
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.477
3tubFPUTyrosine-protein kinase SYK2.7.10.20.477
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
1k749CRRetinoic acid receptor RXR-alpha/0.476
1rdtL79Retinoic acid receptor RXR-alpha/0.476
2o7pNAPRiboflavin biosynthesis protein RibD/0.476
3vt8YI3Vitamin D3 receptor/0.476
5ab6CAANonspecific lipid-transfer protein, putative/0.476
2po7CHDFerrochelatase, mitochondrial4.99.1.10.475
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.475
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.475
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.475
3lalKRVGag-Pol polyprotein2.7.7.490.475
3vtbTKAVitamin D3 receptor/0.475
4jx1CAHCamphor 5-monooxygenase1.14.15.10.475
1bk0ACVIsopenicillin N synthase1.21.3.10.474
2qx7NAPEugenol synthase 11.1.1.3180.474
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.474
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.474
4a99MIYTetX family tetracycline inactivation enzyme/0.474
4a9mP9MBromodomain-containing protein 2/0.474
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.474
1diuBDMDihydrofolate reductase1.5.1.30.473
1jipKTN6-deoxyerythronolide B hydroxylase/0.473
2hw2RFPRifampin ADP-ribosyl transferase/0.473
4iarERM5-hydroxytryptamine receptor 1B/0.473
4l9q9TPSerum albumin/0.473
1dajMOTDihydrofolate reductase1.5.1.30.472
2jb4A14Isopenicillin N synthase1.21.3.10.472
3a4pDFQHepatocyte growth factor receptor2.7.10.10.472
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.472
3pqbVGPPutative oxidoreductase/0.472
4bfxZVXPantothenate kinase2.7.1.330.472
4caxMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.472
4eiyZMAAdenosine receptor A2a/0.472
4iui1GQEstrogen receptor/0.472
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.472
4m8e29VRetinoic acid receptor RXR-alpha/0.472
4m8hR4MRetinoic acid receptor RXR-alpha/0.472
1hfqMOTDihydrofolate reductase1.5.1.30.471
1q6s214Tyrosine-protein phosphatase non-receptor type 13.1.3.480.471
2p15EZTEstrogen receptor/0.471
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.471
3p99LNPLanosterol 14-alpha-demethylase/0.471
3vrwYS5Vitamin D3 receptor/0.471
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.471
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
4itfTFYVitamin D3 receptor/0.471
5d1bTSNHistone deacetylase 83.5.1.980.471
1dhiMTXDihydrofolate reductase1.5.1.30.470
1fm99CRRetinoic acid receptor RXR-alpha/0.470
1hb3SCVIsopenicillin N synthase1.21.3.10.470
1rkgVD1Vitamin D3 receptor/0.470
2iviACWIsopenicillin N synthase1.21.3.10.470
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.470
2zbaZBATrichothecene 3-O-acetyltransferase/0.470
3l0lHC3Nuclear receptor ROR-gamma/0.470
3p2oNADBifunctional protein FolD/0.470
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.470
1crbRTLRetinol-binding protein 1/0.469
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
2jn3JN3Fatty acid-binding protein, liver/0.469
3ad9NADSubunit alpha of sarocosine oxidase/0.469
3cbsR12Cellular retinoic acid-binding protein 2/0.469
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.469
3tdaPN0Cytochrome P450 2D6/0.469
3vtdTKDVitamin D3 receptor/0.469
4a83DXCMajor pollen allergen Bet v 1-A/0.469
4iq71G9Mycocyclosin synthase1.14.21.90.469
4nb6444Nuclear receptor ROR-gamma/0.469
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.469
1hb1OCVIsopenicillin N synthase1.21.3.10.468
1n83CLRNuclear receptor ROR-alpha/0.468
2h42VIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.468
2qw8NAPEugenol synthase 11.1.1.3180.468
2vzmNRBCytochrome P450 monooxygenase PikC/0.468
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.468
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.468
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.468
3tk3CPZCytochrome P450 2B41.14.14.10.468
3vt5YI2Vitamin D3 receptor/0.468
3w0iO11Vitamin D3 receptor/0.468
4eh90OQMitogen-activated protein kinase 14/0.468
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
4iw8KN3Estrogen receptor/0.468
4uymVOR14-alpha sterol demethylase Cyp51B/0.468
1jxzBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.467
1m7aMQUDihydrofolate reductase1.5.1.30.467
2vn0TDZCytochrome P450 2C8/0.467
2zlcVDXVitamin D3 receptor/0.467
3koo24DBifunctional epoxide hydrolase 23.3.2.100.467
3njoPYVAbscisic acid receptor PYR1/0.467
3o8hO8HHTH-type transcriptional regulator EthR/0.467
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
4h9506UDihydrofolate reductase1.5.1.30.467
4iteTEYVitamin D3 receptor/0.467
4j6cSTRCytochrome P450 monooxygenase/0.467
4j6dTESCytochrome P450 monooxygenase/0.467
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.467
4o761M3Bromodomain-containing protein 4/0.467
5k2aZMAAdenosine receptor A2a/0.467
1s3yTQTDihydrofolate reductase1.5.1.30.466
2cl5BIECatechol O-methyltransferase2.1.1.60.466
2hasC3OVitamin D3 receptor/0.466
3ctj320Hepatocyte growth factor receptor2.7.10.10.466
4egnTWOCytochrome P450/0.466
4fhf0TTSpore photoproduct lyase/0.466
4fhi0S4Vitamin D3 receptor A/0.466
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.466
4h9614QDihydrofolate reductase1.5.1.30.466
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.466
4klaCHDFerrochelatase, mitochondrial4.99.1.10.466
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.466
1fm69CRRetinoic acid receptor RXR-alpha/0.465
1ie9VDXVitamin D3 receptor/0.465
1l2jETCEstrogen receptor beta/0.465
1oc1ASVIsopenicillin N synthase1.21.3.10.465
1txtCAAHMG-CoA synthase/0.465
1uykPUXHeat shock protein HSP 90-alpha/0.465
1xiuREARetinoic acid receptor RXR/0.465
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.465
2hb7O1CVitamin D3 receptor/0.465
3jwcEKBDihydrofolate reductase/0.465
3tm5SFGUncharacterized protein/0.465
4bftZVTPantothenate kinase2.7.1.330.465
4ruoBIVVitamin D3 receptor A/0.465
4xe606UDihydrofolate reductase1.5.1.30.465
5dt3ATPAurora kinase A2.7.11.10.465
5jtbZMAAdenosine receptor A2a/0.465
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.464
2w0bCMWLanosterol 14-alpha demethylase1.14.13.700.464
2w6oOA3Biotin carboxylase6.3.4.140.464
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
2xk730ESerine/threonine-protein kinase Nek22.7.11.10.464
3d74NBBPheromone-binding protein ASP1/0.464
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.464
3hub469Mitogen-activated protein kinase 14/0.464
3jynNDPQuinone oxidoreductase/0.464
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.464
3r6c17NAnthranilate phosphoribosyltransferase/0.464
3zkyWT4Isopenicillin N synthase1.21.3.10.464
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.464
3zoiM2WIsopenicillin N synthase1.21.3.10.464
4a51DQ8Kinesin-like protein KIF11/0.464
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.464
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.464
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
4pl9ADPEthylene receptor 1/0.464
5k2bZMAAdenosine receptor A2a/0.464
1qiqACCIsopenicillin N synthase1.21.3.10.463
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.463
1xddAAYIntegrin alpha-L/0.463
1ykdCMPAdenylate cyclase/0.463
2p1u4TNRetinoic acid receptor RXR-alpha/0.463
2q66ATPPoly(A) polymerase2.7.7.190.463
2vf0F89Thymidylate synthase/0.463
3adaNADSubunit alpha of sarocosine oxidase/0.463
3fgoCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.463
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
3l6jZ90Alr2278 protein/0.463
3qj5022Alcohol dehydrogenase class-31.1.1.10.463
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.463
4a9hTVPBromodomain-containing protein 2/0.463
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
4g1d0VKVitamin D3 receptor A/0.463
4k4j1O8Retinoic acid receptor RXR-alpha/0.463
1klkPMDDihydrofolate reductase1.5.1.30.462
1nq7ARLNuclear receptor ROR-beta/0.462
1s0xC3SNuclear receptor ROR-alpha/0.462
1s3vTQDDihydrofolate reductase1.5.1.30.462
1zg32HIIsoflavone 4'-O-methyltransferase/0.462
2bu9HFVIsopenicillin N synthase1.21.3.10.462
2fziDH3Dihydrofolate reductase1.5.1.30.462
2pupADPMethylthioribose kinase2.7.1.1000.462
2yee2ECHeat shock protein HSP 90-alpha/0.462
3d78NBBPheromone-binding protein ASP1/0.462
3gcq1BUMitogen-activated protein kinase 14/0.462
3kytHC2Nuclear receptor ROR-gamma/0.462
3stw2TDMethylketone synthase I/0.462
3v9v21LPeroxisome proliferator-activated receptor gamma/0.462
4a9e3PFBromodomain-containing protein 2/0.462
4b1rITCTetracycline repressor protein class D/0.462
4ele31IDihydrofolate reductase/0.462
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.462
4jlk1NODeoxycytidine kinase2.7.1.740.462
4ktf1TMCytochrome P450/0.462
4x5jFOLDihydrofolate reductase1.5.1.30.462
5dr6SKEAurora kinase A2.7.11.10.462
1ol7ADPAurora kinase A2.7.11.10.461
1ppjSMACytochrome b/0.461
1ysx4EBSerum albumin/0.461
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.461
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.461
2qjySMACytochrome b/0.461
2yboSAHMethyltransferase/0.461
2zl9VDAVitamin D3 receptor/0.461
3t2kFADSulfide-quinone reductase/0.461
3vf60H6Glucokinase2.7.1.20.461
3w0aDS5Vitamin D3 receptor/0.461
4bewCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.461
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.461
4fnyI3KALK tyrosine kinase receptor2.7.10.10.461
4g1z0VPVitamin D3 receptor A/0.461
4xivACPChemotaxis protein CheA2.7.13.30.461
1ezfIN0Squalene synthase2.5.1.210.460
1uy8PU5Heat shock protein HSP 90-alpha/0.460
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
1zgaHMKIsoflavone 4'-O-methyltransferase/0.460
2uxpCLMHTH-type transcriptional regulator TtgR/0.460
3bejMUFBile acid receptor/0.460
3cyz9ODPheromone-binding protein ASP1/0.460
3oapREARetinoic acid receptor RXR-alpha/0.460
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.460
3w0jT08Vitamin D3 receptor/0.460
4bfrJ82Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform2.7.1.1530.460
4dm6TTBRetinoic acid receptor beta/0.460
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4iah1DXAlr2278 protein/0.460
4ivy1GTEstrogen receptor/0.460
4jqh1MFAlr2278 protein/0.460
4jvmXDIEstrogen sulfotransferase2.8.2.40.460
4jx1CAMCamphor 5-monooxygenase1.14.15.10.460
5c1mCLRMu-type opioid receptor/0.460
1n4hREANuclear receptor ROR-beta/0.459
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.459
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
2w4qCBWProstaglandin reductase 21.3.1.480.459
3bqdDAYGlucocorticoid receptor/0.459
3cv9VDXVitamin D3 dihydroxylase/0.459
3vt65YIVitamin D3 receptor/0.459
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.459
4at0FADPossible succinate dehydrogenase/0.459
4bfvZVVPantothenate kinase2.7.1.330.459
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.459
5k2cZMAAdenosine receptor A2a/0.459
1blzACVIsopenicillin N synthase1.21.3.10.458
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.458
1hniAAAGag-Pol polyprotein2.7.7.490.458
1vj3TABDihydrofolate reductase1.5.1.30.458
2e9cB75Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.458
2h94FADLysine-specific histone demethylase 1A10.458
3d73NBBPheromone-binding protein ASP1/0.458
3kb0A8SAbscisic acid receptor PYL2/0.458
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
3umvFADDeoxyribodipyrimidine photo-lyase4.1.99.30.458
3zsh469Mitogen-activated protein kinase 14/0.458
4bfsZVSPantothenate kinase2.7.1.330.458
4cukNAID-lactate dehydrogenase/0.458
4eevL1XHepatocyte growth factor receptor2.7.10.10.458
4g1y0VOVitamin D3 receptor A/0.458
4g2h0VQVitamin D3 receptor A/0.458
4ia2BIVVitamin D3 receptor A/0.458
4r20AERCytochrome P450 family 17 polypeptide 2/0.458
1q4xG24Thyroid hormone receptor beta/0.457
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.457
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
3tmz06XCytochrome P450 2B41.14.14.10.457
3u8hBHPPhospholipase A2, membrane associated/0.457
3vrvYSDVitamin D3 receptor/0.457
3vt3VDXVitamin D3 receptor/0.457
3vt45YIVitamin D3 receptor/0.457
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.457
4jlm1NNDeoxycytidine kinase2.7.1.740.457
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.457
5drdATPAurora kinase A2.7.11.10.457
5h8tRTLRetinol-binding protein 1/0.457
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.456
1rd4L08Integrin alpha-L/0.456
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
2hb8MVDVitamin D3 receptor/0.456
2jlbUDMUncharacterized protein/0.456
2yekEAMBromodomain-containing protein 2/0.456
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.456
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.456
3gieACPSensor histidine kinase DesK2.7.13.30.456
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.456
3ns2PYVAbscisic acid receptor PYL2/0.456
3nwlNDPCatalase1.11.1.60.456
3td8D2RDihydrofolate reductase1.5.1.30.456
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.456
4fhh0U3Vitamin D3 receptor A/0.456
4iv21GREstrogen receptor/0.456
5g53NECAdenosine receptor A2a/0.456
1db1VDXVitamin D3 receptor/0.455
1disBDMDihydrofolate reductase1.5.1.30.455
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1s19MC9Vitamin D3 receptor/0.455
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.455
1yinCM3Estrogen receptor/0.455
2x7hPFNProstaglandin reductase 310.455
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.455
3a783EVVitamin D3 receptor/0.455
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
3eigMTXDihydrofolate reductase1.5.1.30.455
3jw5TOPDihydrofolate reductase/0.455
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
3wv9FEGHmd co-occurring protein HcgE/0.455
4g210VPVitamin D3 receptor A/0.455
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.455
4q0a4OAVitamin D3 receptor A/0.455
5bp9SAHPutative methyltransferase protein/0.455
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.455
1eupASD6-deoxyerythronolide B hydroxylase/0.454
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
1m13HYFNuclear receptor subfamily 1 group I member 2/0.454
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2jizADPATP synthase subunit beta, mitochondrial3.6.3.140.454
2ph5NADHomospermidine synthase/0.454
2uxoTACHTH-type transcriptional regulator TtgR/0.454
2yeiXQIHeat shock protein HSP 90-alpha/0.454
3ds6A17Mitogen-activated protein kinase 14/0.454
3e5aVX6Aurora kinase A2.7.11.10.454
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
3njoP2MAbscisic acid receptor PYR1/0.454
4dscA8SAbscisic acid receptor PYL3/0.454
4efuEFUHeat shock protein HSP 90-alpha/0.454
4ejgNCTCytochrome P450 2A131.14.14.10.454
4inb1F6Gag protein/0.454
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
4ubsDIFPentalenic acid synthase1.14.15.110.454
1hpzAAPGag-Pol polyprotein2.7.7.490.453
1lcoPPYCytochrome b2, mitochondrial1.1.2.30.453
1mc5AHEAlcohol dehydrogenase class-31.1.1.10.453
1mznBM6Retinoic acid receptor RXR-alpha/0.453
1ne4RP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.453
1rkhVD2Vitamin D3 receptor/0.453
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.453
2aibERGBeta-elicitin cinnamomin/0.453
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.453
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.453
2ca0PXICytochrome P450 monooxygenase PikC/0.453
2iwuNP5ATP-dependent molecular chaperone HSP82/0.453
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.453
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.453
2ykcYKCHeat shock protein HSP 90-alpha/0.453
2zb8IMNProstaglandin reductase 21.3.1.480.453
3eon341Glutaryl-CoA dehydrogenase/0.453
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3k47D09Dihydrofolate reductase1.5.1.30.453
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
3tguWF3Cytochrome b/0.453
3vtcTK3Vitamin D3 receptor/0.453
3w5tLHPVitamin D3 receptor/0.453
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.453
4alhA9PBromodomain-containing protein 2/0.453
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.453
4iae1DXAlr2278 protein/0.453
4jlj1NMDeoxycytidine kinase2.7.1.740.453
4mv1ADPBiotin carboxylase6.3.4.140.453
4nc3ERM5-hydroxytryptamine receptor 2B/0.453
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.453
5dr9SKEAurora kinase A2.7.11.10.453
5itzLOCTubulin beta-2B chain/0.453
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.452
1dhfFOLDihydrofolate reductase1.5.1.30.452
1ep4S11Gag-Pol polyprotein2.7.7.490.452
1ia2TQ4Dihydrofolate reductase1.5.1.30.452
1juvNDPDihydrofolate reductase1.5.1.30.452
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.452
1sr7MOFProgesterone receptor/0.452
1u54ACPActivated CDC42 kinase 1/0.452
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.452
1xuoLA1Integrin alpha-L/0.452
2ejzSAHDiphthine synthase/0.452
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.452
2uxhQUEHTH-type transcriptional regulator TtgR/0.452
2vbpVB1Isopenicillin N synthase1.21.3.10.452
2vqoTFGHistone deacetylase 43.5.1.980.452
2wleCOAPolysialic acid O-acetyltransferase/0.452
2xvw9NRSerum albumin/0.452
3cseN22Uncharacterized protein/0.452
3hziATPSerine/threonine-protein kinase toxin HipA/0.452
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
3u4uLNHCasein kinase II subunit alpha2.7.11.10.452
3uvvREARetinoic acid receptor RXR-alpha/0.452
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4l8u9AZSerum albumin/0.452
4xbfFADLysine-specific histone demethylase 1A10.452
5stdUNNScytalone dehydratase4.2.1.940.452
1bygSTUTyrosine-protein kinase CSK/0.451
1cbqRE9Cellular retinoic acid-binding protein 2/0.451
1kkq471Peroxisome proliferator-activated receptor alpha/0.451
1l2iETCEstrogen receptor/0.451
1og5SWFCytochrome P450 2C9/0.451
1prcUQ1Reaction center protein L chain/0.451
1rk3VDXVitamin D3 receptor/0.451
1s0zEB1Vitamin D3 receptor/0.451
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.451
1uhlMEIRetinoic acid receptor RXR-beta/0.451
1vruAAPGag-Pol polyprotein2.7.7.490.451
1w06W05Isopenicillin N synthase1.21.3.10.451
2aclREARetinoic acid receptor RXR-alpha/0.451
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.451
2r6jNDPEugenol synthase 11.1.1.3180.451
2vbdV10Isopenicillin N synthase1.21.3.10.451
2xszATPRuvB-like 23.6.4.120.451
2xvdAS6Ephrin type-B receptor 42.7.10.10.451
3abaFLICytochrome P450/0.451
3antS82Bifunctional epoxide hydrolase 23.3.2.100.451
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3lfcZ86Mitogen-activated protein kinase 14/0.451
3opdHIEHeat shock protein 83/0.451
3qlzQLZUncharacterized protein/0.451
3up3XCAaceDAF-12/0.451
3w0yDS4Vitamin D3 receptor/0.451
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.451
4iwc1GVEstrogen receptor/0.451
4ixeIXEDihydrofolate reductase1.5.1.30.451
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.451
4li61XOTankyrase-12.4.2.300.451
4o71CPBBromodomain-containing protein 4/0.451
4p6wMOFGlucocorticoid receptor/0.451
4q73FADBifunctional protein PutA/0.451
1drbMTXDihydrofolate reductase1.5.1.30.450
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.450
1upw444Oxysterols receptor LXR-beta/0.450
1uzwCDHIsopenicillin N synthase1.21.3.10.450
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2c7gFADNADPH-ferredoxin reductase FprA1.18.1.20.450
2fzhDH1Dihydrofolate reductase1.5.1.30.450
2hamC33Vitamin D3 receptor/0.450
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2q7gCCLPyrrolysine--tRNA ligase/0.450
2y30SM8Putative repressor SimReg2/0.450
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.450
3eta351Insulin receptor2.7.10.10.450
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.450
3hng8STVascular endothelial growth factor receptor 12.7.10.10.450
3irxUDRGag-Pol polyprotein2.7.7.490.450
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.450
3kpzZNEVitamin D3 receptor/0.450
3q0uLL3HTH-type transcriptional regulator EthR/0.450
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.450
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.450
3w5rLOAVitamin D3 receptor/0.450
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.450
3wsbRWZFarnesyltransferase, putative/0.450
3zraORBProgesterone receptor/0.450
4a2jAS0Progesterone receptor/0.450
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.450
4at5MUJBDNF/NT-3 growth factors receptor2.7.10.10.450
4g160VMCasein kinase I isoform gamma-32.7.11.10.450
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.450
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.450
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.450
4jdaA9SAbscisic acid receptor PYL3/0.450
4kwi1TJReductase homolog/0.450
4l9kEHFSerum albumin/0.450
4zowCLMMultidrug transporter MdfA/0.450
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.449
1bmfADPATP synthase subunit alpha, mitochondrial/0.449
1bmfADPATP synthase subunit beta, mitochondrial3.6.3.140.449
1cd2FOLDihydrofolate reductase1.5.1.30.449
1hk2T44Serum albumin/0.449
1jlaTNKGag-Pol polyprotein2.7.7.490.449
1kl2FONSerine hydroxymethyltransferase/0.449
1p7tACOMalate synthase G/0.449
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.449
1xl2189Gag-Pol polyprotein3.4.23.160.449
1zhzERGOxysterol-binding protein homolog 4/0.449
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.449
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.449
2giuFBREstrogen receptor beta/0.449
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.449
2xlsFADPutative flavin-containing monooxygenase/0.449
3gc9B45Mitogen-activated protein kinase 112.7.11.240.449
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3l8p0CEAngiopoietin-1 receptor2.7.10.10.449
3l8sBFFMitogen-activated protein kinase 14/0.449
3mdvCL6Cholesterol 24-hydroxylase/0.449
3o8gO8GHTH-type transcriptional regulator EthR/0.449
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.449
3t8xT8XT-cell surface glycoprotein CD1b/0.449
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.449
3wgwT2BProliferating cell nuclear antigen/0.449
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.449
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.449
4c3yANB3-ketosteroid dehydrogenase/0.449
4c9oCAMCytochrome P450/0.449
4h6uACOAlpha-tubulin N-acetyltransferase 1/0.449
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.449
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.449
4pd6URINucleoside permease/0.449
4qa0SHHHistone deacetylase 83.5.1.980.449
4zukNADAlpha-aminoadipic semialdehyde dehydrogenase1.2.1.310.449
3emlZMAAdenosine receptor A2a/0.449
1bzfTMQDihydrofolate reductase1.5.1.30.448
1cbsREACellular retinoic acid-binding protein 2/0.448
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
1iyzNDPProbable quinone oxidoreductase/0.448
1mj3HXCEnoyl-CoA hydratase, mitochondrial4.2.1.170.448
1uy7PU4Heat shock protein HSP 90-alpha/0.448
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.448
2pulACPMethylthioribose kinase2.7.1.1000.448
2uxuNARHTH-type transcriptional regulator TtgR/0.448
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.448
2y60M8FIsopenicillin N synthase1.21.3.10.448
2z4bDC8Estrogen receptor beta/0.448
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.448
3dxjNE6DNA-directed RNA polymerase subunit beta/0.448
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.448
3eel53TUncharacterized protein/0.448
3h4vDVPPteridine reductase 11.5.1.330.448
3jwm5WBDihydrofolate reductase/0.448
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.448
3nr4PYVAbscisic acid receptor PYL2/0.448
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
4bfwZVWPantothenate kinase2.7.1.330.448
4dvq1CACytochrome P450 11B2, mitochondrial1.14.15.40.448
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.448
4g2gTDHMycocyclosin synthase1.14.21.90.448
4hyf1AKTankyrase-22.4.2.300.448
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.448
4ict1EDMycocyclosin synthase1.14.21.90.448
4ixfIXFDihydrofolate reductase1.5.1.30.448
4j6bPLOCytochrome P450 monooxygenase/0.448
1i58ACPChemotaxis protein CheA2.7.13.30.447
1i59ADPChemotaxis protein CheA2.7.13.30.447
1ja1FADNADPH--cytochrome P450 reductase/0.447
1ly4COQDihydrofolate reductase1.5.1.30.447
1pp9SMACytochrome b/0.447
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.447
1qjfACSIsopenicillin N synthase1.21.3.10.447
1re9DSOCamphor 5-monooxygenase1.14.15.10.447
1rfvADPPyridoxal kinase2.7.1.350.447
1rx7FOLDihydrofolate reductase1.5.1.30.447
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.447
1yvj4STTyrosine-protein kinase JAK32.7.10.20.447
1zhwHC2Oxysterol-binding protein homolog 4/0.447
2bxmIMNSerum albumin/0.447
2dv5SAHDiphthine synthase/0.447
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.447
2rabNADGlutathione amide reductase/0.447
2rhrEMOPutative ketoacyl reductase1.3.10.447
3bzuA21Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3deiRXBCaspase-33.4.22.560.447
3is9AC7Gag-Pol polyprotein2.7.7.490.447
3pnfH4BNitric oxide synthase, brain1.14.13.390.447
3r5zF42Uncharacterized protein/0.447
3wd7COAAcridone synthase/0.447
4bb3KKAIsopenicillin N synthase1.21.3.10.447
4cdmFO1Deoxyribodipyrimidine photolyase/0.447
4equG6ISerine/threonine-protein kinase 102.7.11.10.447
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4g95OAGDihydrofolate reductase1.5.1.30.447
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.447
4h9814QUncharacterized protein/0.447
4ips1G4Mycocyclosin synthase1.14.21.90.447
4kfp1R7Nicotinamide phosphoribosyltransferase2.4.2.120.447
4mt92D6Tankyrase-12.4.2.300.447
4zhiADPKinesin-like protein KIF11/0.447
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.446
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.446
1bozPRDDihydrofolate reductase1.5.1.30.446
1fvpFMANon-fluorescent flavoprotein/0.446
1i58ADPChemotaxis protein CheA2.7.13.30.446
1yhoTRRDihydrofolate reductase1.5.1.30.446
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.446
2bxqIMNSerum albumin/0.446
2c7xNRBCytochrome P450 monooxygenase PikC/0.446
2ed3SAHDiphthine synthase/0.446
2gvcFADThiol-specific monooxygenase1.14.130.446
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
2p33J07Mitogen-activated protein kinase 102.7.11.240.446
3c3dFO12-phospho-L-lactate transferase/0.446
3d90NOGProgesterone receptor/0.446
3vruYS3Vitamin D3 receptor/0.446
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.446
4a28ADPKinesin-like protein KIF11/0.446
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.446
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.446
4dsbA8SAbscisic acid receptor PYL3/0.446
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
4lwwLWWNicotinamide phosphoribosyltransferase2.4.2.120.446
4rujVDXVitamin D3 receptor A/0.446
1lhwESMSex hormone-binding globulin/0.445
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2btsU32Cyclin-dependent kinase 22.7.11.220.445
2cd2FOLDihydrofolate reductase1.5.1.30.445
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.445
2ipjFFAAldo-keto reductase family 1 member C2/0.445
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.445
2xk85R1Serine/threonine-protein kinase Nek22.7.11.10.445
2ydoADNAdenosine receptor A2a/0.445
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.445
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.445
3cr7PPSAdenylyl-sulfate kinase2.7.1.250.445
3d2dRENReticuline oxidase1.21.3.30.445
3d76NBBPheromone-binding protein ASP1/0.445
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.445
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.445
3sa27DRDihydrofolate reductase/0.445
3up0D7SaceDAF-12/0.445
3zkpERBErythromycin C-12 hydroxylase1.14.13.1540.445
4jr51LSNicotinamide phosphoribosyltransferase2.4.2.120.445
4oqyNDP(S)-imine reductase/0.445
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.445
4tyj0LIFibroblast growth factor receptor 42.7.10.10.445
4u0k744Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
1fcy564Retinoic acid receptor gamma/0.444
1g63FMNEpidermin decarboxylase4.1.10.444
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.444
1jioDEB6-deoxyerythronolide B hydroxylase/0.444
1kzjCB3Thymidylate synthase/0.444
1lriCLRBeta-elicitin cryptogein/0.444
1n5qTNCActVA 6 protein/0.444
1rgsCMPcAMP-dependent protein kinase type I-alpha regulatory subunit/0.444
1sqbAZOCytochrome b/0.444
1tdrMTXDihydrofolate reductase1.5.1.30.444
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.444
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2bf7HBIPteridine reductase 11.5.1.330.444
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
2i0ePDSProtein kinase C beta type2.7.11.130.444
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.444
2lbaCHOFatty acid binding protein 6/0.444
2nn7M29Carbonic anhydrase 14.2.1.10.444
2oh4GIGVascular endothelial growth factor receptor 22.7.10.10.444
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2piwDHTAndrogen receptor/0.444
2wepADPATP-dependent molecular chaperone HSP82/0.444
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.444
2yac937Serine/threonine-protein kinase PLK12.7.11.210.444
3datMTXDihydrofolate reductase/0.444
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.444
3fyvXCFDihydrofolate reductase1.5.1.30.444
3g5hYTTMycocyclosin synthase1.14.21.90.444
3g70A5TRenin3.4.23.150.444
3gncQQQGlutaryl-CoA dehydrogenase/0.444
3hz142CHeat shock protein HSP 90-alpha/0.444
3n5vH4BNitric oxide synthase, brain1.14.13.390.444
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.444
3q44D50M1 family aminopeptidase3.4.110.444
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4c3rACPAurora kinase A2.7.11.10.444
4cdmFADDeoxyribodipyrimidine photolyase/0.444
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.444
4g47TZFMycocyclosin synthase1.14.21.90.444
4gevCB3Thymidylate synthase/0.444
4jbtASDCytochrome P450 monooxygenase/0.444
4ktl1CQCytochrome P450/0.444
4qjqOTRLactoperoxidase/0.444
4zcaADPKinesin-like protein KIF11/0.444
1ci7CB3Thymidylate synthase2.1.1.450.443
1fbyREARetinoic acid receptor RXR-alpha/0.443
1ia3TQ5Dihydrofolate reductase1.5.1.30.443
1k6vXN2Gag-Pol polyprotein3.4.23.160.443
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.443
1sn0T44Transthyretin/0.443
1txiTX5Vitamin D3 receptor/0.443
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.443
1vzdCB3Thymidylate synthase/0.443
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.443
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.443
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2j0vGDPRac-like GTP-binding protein ARAC7/0.443
2j5sKTAAlr4455 protein/0.443
2p1v5TNRetinoic acid receptor RXR-alpha/0.443
2vd0D27Hematopoietic prostaglandin D synthase/0.443
2xa4AZ5Tyrosine-protein kinase JAK2/0.443
2xf3J01Uncharacterized protein/0.443
2yatEEUEstrogen receptor/0.443
3b9lAZZSerum albumin/0.443
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
3i0rRT3Gag-Pol polyprotein2.7.7.490.443
3icrCOACoenzyme A disulfide reductase/0.443
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3n65XFJNitric oxide synthase, brain1.14.13.390.443
3pg3DG7Mitogen-activated protein kinase 14/0.443
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.443
3vufADPGranule-bound starch synthase 1, chloroplastic/amyloplastic2.4.1.2420.443
4dbw511Aldo-keto reductase family 1 member C3/0.443
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4elb34RDihydrofolate reductase/0.443
4h1j0YHProtein-tyrosine kinase 2-beta2.7.10.20.443
4imuH4BNitric oxide synthase, brain1.14.13.390.443
4j24ESTEstrogen receptor beta/0.443
4o2z046Mitogen-activated protein kinase/0.443
4o4eATPKinase/0.443
4wa9AXITyrosine-protein kinase ABL12.7.10.20.443
1dz6CAMCamphor 5-monooxygenase1.14.15.10.442
1fmlRTLRetinol dehydratase/0.442
1i5aACPChemotaxis protein CheA2.7.13.30.442
1iwjCAMCamphor 5-monooxygenase1.14.15.10.442
1m2zDEXGlucocorticoid receptor/0.442
1m78CLZDihydrofolate reductase1.5.1.30.442
1qxlFR8Adenosine deaminase3.5.4.40.442
1v7aFRCAdenosine deaminase3.5.4.40.442
1w2cANPInositol-trisphosphate 3-kinase A2.7.1.1270.442
1zeoC01Peroxisome proliferator-activated receptor gamma/0.442
2apgFADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.442
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.442
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.442
2g5oDRQEstrogen receptor/0.442
2p2xSAHDiphthine synthase/0.442
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.442
2y3sTIRTamL/0.442
2znnS44Peroxisome proliferator-activated receptor alpha/0.442
3da24MDCarbonic anhydrase 134.2.1.10.442
3gobHXXDdmC/0.442
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3poz03PEpidermal growth factor receptor2.7.10.10.442
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.442
3wixLC3Induced myeloid leukemia cell differentiation protein Mcl-1/0.442
4a81DXCMajor pollen allergen Bet v 1-A/0.442
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.442
4bcmT7ZCyclin-dependent kinase 22.7.11.220.442
4bmpFMNProtein NrdI/0.442
4elb34SDihydrofolate reductase/0.442
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.442
4g3jVNTLanosterol 14-alpha-demethylase/0.442
4hgt15GCasein kinase I isoform delta2.7.11.10.442
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.442
4i7fNVEGag-Pol polyprotein2.7.7.490.442
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.442
4jseH4BNitric oxide synthase, brain1.14.13.390.442
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.442
4zp0DXCMultidrug transporter MdfA/0.442
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.442
1e1lNAPNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.441
1e7aPFLSerum albumin/0.441
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1jpaANPEphrin type-B receptor 22.7.10.10.441
1kijNOVDNA gyrase subunit B/0.441
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
1rf9DBRCamphor 5-monooxygenase1.14.15.10.441
1vrwNAIEnoyl-ACP reductase/0.441
2abi1CAMineralocorticoid receptor/0.441
2bxiAZQSerum albumin/0.441
2dbzNAPGlyoxylate reductase1.1.1.260.441
2iw94SPCyclin-dependent kinase 22.7.11.220.441
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.441
2yiuSMACytochrome b/0.441
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.441
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.441
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.441
3dleGFAGag-Pol polyprotein2.7.7.490.441
3e01PZ2Gag-Pol polyprotein2.7.7.490.441
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.441
3h1jSMACytochrome b/0.441
3h3sH15Collagen type IV alpha-3-binding protein/0.441
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.441
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.441
3negPYVAbscisic acid receptor PYL1/0.441
3oibFDAPutative acyl-CoA dehydrogenase/0.441
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.441
3w0hW12Vitamin D3 receptor/0.441
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.441
4a9iP9IBromodomain-containing protein 2/0.441
4aosNAPSteroid monooxygenase/0.441
4cd2FOLDihydrofolate reductase1.5.1.30.441
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4ez72ANCyclin-dependent kinase 22.7.11.220.441
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4jboWPHAurora kinase A2.7.11.10.441
4m2xTMQDihydrofolate reductase1.5.1.30.441
4uajFADNa(+)-translocating NADH-quinone reductase subunit F/0.441
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.441
4yutFMNFamily 3 adenylate cyclase/0.441
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
7catNDPCatalase1.11.1.60.441
1fm4DXCMajor pollen allergen Bet v 1-L/0.440
1fmjRTLRetinol dehydratase/0.440
1lquNDPNADPH-ferredoxin reductase FprA1.18.1.20.440
1mvcBM6Retinoic acid receptor RXR-alpha/0.440
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.440
1tz8DESTransthyretin/0.440
1uy6PU3Heat shock protein HSP 90-alpha/0.440
1xefATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.440
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.440
2fhjMFNFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.440
2gs9SAHUncharacterized protein/0.440
2hkoFADLysine-specific histone demethylase 1A10.440
2ocfESTEstrogen receptor/0.440
2pchSAHDiphthine synthase/0.440
2wqeADPAurora kinase A2.7.11.10.440
2zjwREFCasein kinase II subunit alpha2.7.11.10.440
3cz09ODPheromone-binding protein ASP1/0.440
3eej53RUncharacterized protein/0.440
3eem53VUncharacterized protein/0.440
3erdDESEstrogen receptor/0.440
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.440
3jziJZLBiotin carboxylase6.3.4.140.440
3lu7IPXSerum albumin/0.440
3mpaSB2Mitogen-activated protein kinase 14/0.440
3nefPYVAbscisic acid receptor PYL1/0.440
3nlz3XDNitric oxide synthase, brain1.14.13.390.440
3t2zFADSulfide-quinone reductase/0.440
4boeCLRJapanin/0.440
4e5yNDPGDP-L-fucose synthase1.1.1.2710.440
4ejh0QACytochrome P450 2A131.14.14.10.440
4fkpLS5Cyclin-dependent kinase 22.7.11.220.440
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.440
4grb0XGCasein kinase II subunit alpha2.7.11.10.440
4ipw1G7Mycocyclosin synthase1.14.21.90.440
4r21STRCytochrome P450 family 17 polypeptide 2/0.440
4v12POGMaoC like domain protein/0.440
4xoqF42Coenzyme F420:L-glutamate ligase/0.440
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.440