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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ehuANP2-hydroxyisocaproyl-CoA dehydratase activator

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4ehuANP2-hydroxyisocaproyl-CoA dehydratase activator/1.000
4ehtADP2-hydroxyisocaproyl-CoA dehydratase activator/0.609
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.461
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.444
3d8vUD1Bifunctional protein GlmU/0.444
3dogNNNCyclin-dependent kinase 22.7.11.220.444
4q72FADBifunctional protein PutA/0.442
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.440
2vtbFADCryptochrome DASH, chloroplastic/mitochondrial/0.440
3wquATPCell division protein FtsA/0.440