sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 1.000 | |
| 3gye | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.661 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.625 | |
| 3c3n | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.616 | |
| 4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.613 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.600 | |
| 4wzh | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.595 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.590 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.565 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.557 | |
| 2bsl | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.553 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.469 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.466 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.461 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.456 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.452 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.449 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.448 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.448 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.447 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.445 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.443 | |
| 1jub | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.442 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.441 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.441 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 3r95 | ACO | MccE protein | / | 0.440 |