Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 1.000 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.564 | |
| 3ce3 | 1FN | Hepatocyte growth factor receptor | 2.7.10.1 | 0.532 | |
| 4eyj | N61 | Mitogen-activated protein kinase 13 | 2.7.11.24 | 0.455 | |
| 4agw | NG7 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.451 | |
| 3eta | 351 | Insulin receptor | 2.7.10.1 | 0.449 | |
| 2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.446 | |
| 4kao | KAO | Focal adhesion kinase 1 | 2.7.10.2 | 0.446 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 |