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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ed4ATP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4ed4ATP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/1.000
2v8pADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.569
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.548
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.503
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.496
1zmdNAIDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.494
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.494
3otwCOAPhosphopantetheine adenylyltransferase/0.493
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.487
4yagNAIC alpha-dehydrogenase/0.486
4yaiNAIC alpha-dehydrogenase/0.486
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.483
4gxs0YSGlutamate receptor 2/0.483
4e2bFMNDehydrogenase/0.482
3q44D50M1 family aminopeptidase3.4.110.479
3atzFMNProstaglandin F2a synthase/0.478
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.478
1cf3FADGlucose oxidase1.1.3.40.477
2rcyNAPPyrroline-5-carboxylate reductase/0.477
4m83ERYOleandomycin glycosyltransferase2.4.10.477
2a7r5GPGMP reductase 2/0.476
2r43G3GGag-Pol polyprotein3.4.23.160.476
2x0iNAIMalate dehydrogenase/0.476
3uylTYDProbable NDP-rhamnosyltransferase/0.476
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.476
3gobHXXDdmC/0.475
4nbwNADShort-chain dehydrogenase/reductase SDR/0.475
4q71FADBifunctional protein PutA/0.475
4q73FADBifunctional protein PutA/0.475
4xiwAZMCarbonic anhydrase, alpha type/0.475
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.474
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.474
1zrzBI1Protein kinase C iota type2.7.11.130.473
3cgeNDPCoenzyme A disulfide reductase/0.473
3hyoADPPyridoxal kinase/0.473
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.472
3kfr3TLGag-Pol polyprotein/0.472
3zhyFM61-deoxy-D-xylulose 5-phosphate reductoisomerase/0.472
3zptM8YGag-Pol polyprotein3.4.23.160.472
1fwkADPHomoserine kinase2.7.1.390.471
3ksdNADGlyceraldehyde-3-phosphate dehydrogenase 1/0.471
3lqfNADGalactitol dehydrogenase/0.471
1b2lNDCAlcohol dehydrogenase1.1.1.10.470
1g1aNADdTDP-glucose 4,6-dehydratase/0.470
2ikuLIYRenin3.4.23.150.470
2uxoTACHTH-type transcriptional regulator TtgR/0.470
2w6zL21Biotin carboxylase6.3.4.140.470
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.470
3q43D66M1 family aminopeptidase3.4.110.470
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.470
1dhjMTXDihydrofolate reductase1.5.1.30.469
1dnpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.469
1e3eNAIAlcohol dehydrogenase 41.1.1.10.469
1txtCAAHMG-CoA synthase/0.469
2qnqQN3Gag-Pol polyprotein3.4.23.160.469
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.469
3u9eCOALmo1369 protein/0.469
4du82P0Mevalonate diphosphate decarboxylase/0.469
1u3dFADCryptochrome-1/0.468
2pwcG3GGag-Pol polyprotein3.4.23.160.468
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.468
4a6bQG8Gag-Pol polyprotein3.4.23.160.468
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.468
4n6hEJ4Delta-type opioid receptor/0.468
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.467
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.467
1lbcCYZGlutamate receptor 2/0.467
1t7j478Gag-Pol polyprotein3.4.23.160.467
1t88CAMCamphor 5-monooxygenase1.14.15.10.467
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.467
2vn0TDZCytochrome P450 2C8/0.467
3b70NAPEnoyl reductase LovC10.467
3cgdNADCoenzyme A disulfide reductase/0.467
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
4cdmFO1Deoxyribodipyrimidine photolyase/0.467
1h73ANPHomoserine kinase2.7.1.390.466
1jioDEB6-deoxyerythronolide B hydroxylase/0.466
1t85CAMCamphor 5-monooxygenase1.14.15.10.466
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.466
2p5uNADUDP-glucose 4-epimerase/0.466
3p67FMNPentaerythritol tetranitrate reductase/0.466
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
1xe55FEPlasmepsin-23.4.23.390.465
2y3rTRKTamL/0.465
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
3dagFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.465
3ru9NADUDP-N-acetylglucosamine 4-epimerase/0.465
4loi1YCStimulator of interferon genes protein/0.465
1u4oNDDL-lactate dehydrogenase1.1.1.270.464
2o4cNADErythronate-4-phosphate dehydrogenase/0.464
2qboCAMCamphor 5-monooxygenase1.14.15.10.464
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.464
2x3nFADProbable FAD-dependent monooxygenase/0.464
3nbvANPKetohexokinase/0.464
3p62FMNPentaerythritol tetranitrate reductase/0.464
4k6fNAPPutative Acetoacetyl-CoA reductase/0.464
2cy0NAPShikimate dehydrogenase (NADP(+))/0.463
3f03FMNPentaerythritol tetranitrate reductase/0.463
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.463
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.463
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
1pjcNADAlanine dehydrogenase/0.462
1vyrFMNPentaerythritol tetranitrate reductase/0.462
2ejvNADL-threonine 3-dehydrogenase/0.462
3c1y2BADNA integrity scanning protein DisA/0.462
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.462
1c6zROCProtease/0.461
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1vzdCB3Thymidylate synthase/0.461
3copADPGlycogen synthase2.4.1.210.461
3gpcCOAAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.461
4a8v2ANMajor pollen allergen Bet v 1-J/0.461
4b99R4LMitogen-activated protein kinase 72.7.11.240.461
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1dhiMTXDihydrofolate reductase1.5.1.30.460
1fy7COAHistone acetyltransferase ESA1/0.460
1u4dDBQActivated CDC42 kinase 1/0.460
1vi2NADQuinate/shikimate dehydrogenase/0.460
2g8yNADHydroxycarboxylate dehydrogenase B/0.460
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.460
3b9oFMNAlkane monoxygenase/0.460
3oxv478Gag-Pol polyprotein3.4.23.160.460
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.460
4h6rFDAProline dehydrogenase/0.460
4yaoFMNNADPH--cytochrome P450 reductase/0.460
1u0hFOKAdenylate cyclase type 2/0.459
1u0hFOKAdenylate cyclase type 5/0.459
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.459
2ou2ACOHistone acetyltransferase KAT5/0.459
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.459
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.459
3p82FMNPentaerythritol tetranitrate reductase/0.459
4bb3KKAIsopenicillin N synthase1.21.3.10.459
4djaFAD(6-4) photolyase/0.459
4m4922YL-lactate dehydrogenase A chain1.1.1.270.459
4u03GTPCyclic GMP-AMP synthase/0.459
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1mk1APRMutT/nudix family protein/0.458
1psa0ZLPepsin A3.4.23.10.458
2ft9CHDFatty acid-binding protein 2, liver/0.458
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.458
3frqERYErythromycin resistance repressor protein/0.458
3fwfCAMCamphor 5-monooxygenase1.14.15.10.458
3fwjCAMCamphor 5-monooxygenase1.14.15.10.458
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.458
3kb1ADPIron-sulfur cluster carrier protein/0.458
3mk6ACOPantothenate kinase 32.7.1.330.458
4e2dFMNDehydrogenase/0.458
4jicFMNGTN Reductase/0.458
5a9sNAPPutative dehydrogenase/0.458
1bwb146Gag-Pol polyprotein3.4.23.160.457
1mjbACOHistone acetyltransferase ESA1/0.457
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.457
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.457
2gjlFMNNitronate monooxygenase1.13.12.160.457
2j5xGSPADP-ribosylation factor 6/0.457
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.457
2y4gTIRTamL/0.457
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.457
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.457
1h63FMNPentaerythritol tetranitrate reductase/0.456
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.456
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1kkq471Peroxisome proliferator-activated receptor alpha/0.456
3ibqATPPyridoxal kinase/0.456
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.456
3p84FMNPentaerythritol tetranitrate reductase/0.456
4a862ANMajor pollen allergen Bet v 1-A/0.456
4dbzNDPPutative ketoacyl reductase1.3.10.456
1dirNADDihydropteridine reductase1.5.1.340.455
1mjaCOAHistone acetyltransferase ESA1/0.455
2abbFMNPentaerythritol tetranitrate reductase/0.455
2hldANPATP synthase subunit alpha, mitochondrial/0.455
2hldANPATP synthase subunit beta, mitochondrial3.6.3.140.455
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.455
3qrwNDPPutative ketoacyl reductase1.3.10.455
3rk1ATPN-type ATP pyrophosphatase superfamily/0.455
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.455
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.455
4qgiROCGag-Pol polyprotein3.4.23.160.455
4rnuFMNNADPH dehydrogenase 11.6.99.10.455
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.455
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.455
5cnsCDPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.455
1bwsNDPGDP-L-fucose synthase/0.454
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.454
1fxsNAPGDP-L-fucose synthase/0.454
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
2b36NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2feuCAMCamphor 5-monooxygenase1.14.15.10.454
2i7pACOPantothenate kinase 32.7.1.330.454
2v59LZKBiotin carboxylase6.3.4.140.454
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.454
3h06VBPGlutamate receptor 2/0.454
3i0pNADMalate dehydrogenase, putative/0.454
3ieuGDPGTPase Era/0.454
3imgBZ2Pantothenate synthetase6.3.2.10.454
3lshFADPyranose 2-oxidase/0.454
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.454
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.454
4f9gC2EStimulator of interferon genes protein/0.454
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.454
1h51FMNPentaerythritol tetranitrate reductase/0.453
1jmhUMPThymidylate synthase/0.453
1rfuADPPyridoxal kinase2.7.1.350.453
1rj6AZMCarbonic anhydrase 144.2.1.10.453
1t7i017Gag-Pol polyprotein3.4.23.160.453
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.453
2qbuSAHPrecorrin-2 methyltransferase/0.453
3a1nNADNDP-sugar epimerase/0.453
3jziJZLBiotin carboxylase6.3.4.140.453
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.453
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4i1iNADMalate dehydrogenase/0.453
4k28NADShikimate dehydrogenase family protein/0.453
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.453
1ezvUQ6Cytochrome b/0.452
1g6cTZPThiamine-phosphate synthase/0.452
1gteFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.452
1guyNADMalate dehydrogenase/0.452
1h50FMNPentaerythritol tetranitrate reductase/0.452
1nzdUPGDNA beta-glucosyltransferase/0.452
1rm4NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.452
1w6hTITPlasmepsin-23.4.23.390.452
2iyfERYOleandomycin glycosyltransferase2.4.10.452
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.452
4ambDUDPutative glycosyl transferase/0.452
4hmvWUBPhenazine biosynthesis protein PhzG1.40.452
4ips1G4Mycocyclosin synthase1.14.21.90.452
4ipw1G7Mycocyclosin synthase1.14.21.90.452
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.452
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.452
5dp2NAPCurF/0.452
1bsvNDPGDP-L-fucose synthase/0.451
1ipeNDPTropinone reductase 21.1.1.2360.451
2avvMK1Gag-Pol polyprotein3.4.23.160.451
2b56UTPRNA editing complex protein MP57/0.451
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.451
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.451
2f3kRO1Protease/0.451
3h3t16HCollagen type IV alpha-3-binding protein/0.451
3qwbNDPProbable quinone oxidoreductase1.6.5.50.451
3t2zFADSulfide-quinone reductase/0.451
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.451
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.451
4oqyNDP(S)-imine reductase/0.451
5hg0SAMPantothenate synthetase/0.451
1bwaXV6Gag-Pol polyprotein3.4.23.160.450
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.450
1f8wFADNADH peroxidase1.11.1.10.450
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.450
1k6tXN1Gag-Pol polyprotein3.4.23.160.450
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.450
1xddAAYIntegrin alpha-L/0.450
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.450
3muoZPRProlyl endopeptidase/0.450
4a802ANMajor pollen allergen Bet v 1-A/0.450
4a99FADTetX family tetracycline inactivation enzyme/0.450
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4kwhNAPReductase homolog/0.450
4u2sFDACholesterol oxidase1.1.3.60.450
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.450
1ddrMTXDihydrofolate reductase1.5.1.30.449
1jpaANPEphrin type-B receptor 22.7.10.10.449
1o9bNAIQuinate/shikimate dehydrogenase/0.449
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.449
1yonA2R2-dehydropantoate 2-reductase1.1.1.1690.449
2ahrNAPPyrroline-5-carboxylate reductase/0.449
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.449
2y3sTIRTamL/0.449
3a4vNADNDP-sugar epimerase/0.449
3drcMTXDihydrofolate reductase1.5.1.30.449
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.449
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.449
3t2kFADSulfide-quinone reductase/0.449
3t3c017Gag-Pol polyprotein3.4.23.160.449
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.449
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.449
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.449
4nm9FADBifunctional protein PutA/0.449
5a3bAPRSIR2 family protein/0.449
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.448
1icsFMN12-oxophytodienoate reductase 11.3.1.420.448
1mesDMPGag-Pol polyprotein3.4.23.160.448
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.448
1o76CAMCamphor 5-monooxygenase1.14.15.10.448
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.448
2briANPUridylate kinase2.7.4.220.448
2gstGPSGlutathione S-transferase Mu 12.5.1.180.448
2j4dFADCryptochrome DASH, chloroplastic/mitochondrial/0.448
2ohvNHLGlutamate racemase/0.448
3d4pNADL-lactate dehydrogenase 11.1.1.270.448
3d8vUD1Bifunctional protein GlmU/0.448
3fwgCAMCamphor 5-monooxygenase1.14.15.10.448
3hz5Z64Heat shock protein HSP 90-alpha/0.448
3p8jFMNPentaerythritol tetranitrate reductase/0.448
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.448
4bfxZVXPantothenate kinase2.7.1.330.448
4f9fGDPPutative glycosyltransferase/0.448
4m55NADUDP-glucuronic acid decarboxylase 14.1.1.350.448
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.448
4p63NADProbable deoxyhypusine synthase2.5.1.460.448
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.448
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.448
1k6pXN3Gag-Pol polyprotein3.4.23.160.447
1kh3ANPArgininosuccinate synthase/0.447
1msmJE2Gag-Pol polyprotein3.4.23.160.447
1owpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.447
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.447
2pwrG4GGag-Pol polyprotein3.4.23.160.447
2xhd7T9Glutamate receptor 2/0.447
3a3gDLZLumazine protein/0.447
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.447
3gbuATPUncharacterized sugar kinase PH14592.7.10.447
3kpbSAMUncharacterized protein MJ0100/0.447
3kpkFADSulfide-quinone reductase/0.447
3nr4PYVAbscisic acid receptor PYL2/0.447
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4cd2FOLDihydrofolate reductase1.5.1.30.447
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.447
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.447
4ocvANPAminoglycoside phosphotransferase/0.447
4rlsNAIL-lactate dehydrogenase A chain1.1.1.270.447
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.446
1mg5NAIAlcohol dehydrogenase1.1.1.10.446
1nzfUPGDNA beta-glucosyltransferase/0.446
1sdwIYTPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.446
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.446
2bpw1INGag-Pol polyprotein3.4.23.160.446
2fb2SAMGTP 3',8-cyclase4.1.99.180.446
2givACOHistone acetyltransferase KAT8/0.446
2harOCCVitamin D3 receptor/0.446
2jn3JN3Fatty acid-binding protein, liver/0.446
2znoS44Peroxisome proliferator-activated receptor gamma/0.446
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.446
3f1kNAPUncharacterized oxidoreductase YciK10.446
3il1B5DGlutamate receptor 2/0.446
3sglFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.446
3sm2478Putative gag-pro-pol polyprotein/0.446
3tjzGNPADP-ribosylation factor 1/0.446
3zkyWT4Isopenicillin N synthase1.21.3.10.446
4bfvZVVPantothenate kinase2.7.1.330.446
4h1e10JBeta-secretase 13.4.23.460.446
5a3cNADSIR2 family protein/0.446
5cwa0GAAnthranilate synthase component 14.1.3.270.446
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
1meiXMPInosine-5'-monophosphate dehydrogenase/0.445
1mqeAPRMutT/nudix family protein/0.445
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.445
1sbgIM1Gag-Pol polyprotein/0.445
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
1zmcNADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.445
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.445
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.445
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.445
2wsbNADGalactitol dehydrogenase/0.445
3cgfJNFMitogen-activated protein kinase 102.7.11.240.445
3p74FMNPentaerythritol tetranitrate reductase/0.445
3qpjN4IGag-Pol polyprotein3.4.23.160.445
3tz3B36Acetyl-CoA carboxylase/0.445
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3vglANPGlucokinase/0.445
4a87NARMajor pollen allergen Bet v 1-A/0.445
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.445
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.445
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.445
1bwlFMNNADPH dehydrogenase 11.6.99.10.444
1dz8CAMCamphor 5-monooxygenase1.14.15.10.444
1h74AGSHomoserine kinase2.7.1.390.444
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.444
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.444
1rfvADPPyridoxal kinase2.7.1.350.444
1vbiNADMalate/L-lactate dehydrogenase family protein/0.444
2a87FADThioredoxin reductase1.8.1.90.444
2fxeDR7Gag-Pol polyprotein3.4.23.160.444
2fzwNADAlcohol dehydrogenase class-31.1.1.10.444
2he5NDPAldo-keto reductase family 1 member C211.1.10.444
2hfuMEVMevalonate kinase/0.444
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.444
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.444
3fnlSHALactoperoxidase/0.444
3fr5I4AFatty acid-binding protein, adipocyte/0.444
3nxxNDPDihydrofolate reductase1.5.1.30.444
3oibFDAPutative acyl-CoA dehydrogenase/0.444
3otxAP5Adenosine kinase, putative/0.444
3rpeFADPutative modulator of drug activity/0.444
3slkNDPPolyketide synthase extender module 2/0.444
4b4oNDPEpimerase family protein SDR39U1/0.444
4emtC2EStimulator of interferon genes protein/0.444
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.444
4l4eCAMCamphor 5-monooxygenase1.14.15.10.444
4ryvZEAProtein LlR18A/0.444
4tmcFMNOld yellow enzyme/0.444
4udrFAD5-(hydroxymethyl)furfural oxidase/0.444
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.444
1iqrFADDeoxyribodipyrimidine photo-lyase4.1.99.30.443
1np7FADCryptochrome DASH/0.443
1nvtNAPShikimate dehydrogenase (NADP(+))/0.443
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.443
2c29NAPDihydroflavonol 4-reductase/0.443
2c6dANPAurora kinase A2.7.11.10.443
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.443
2ituITQEpidermal growth factor receptor2.7.10.10.443
2nnkROCProtease/0.443
2ozuACOHistone acetyltransferase KAT6A/0.443
2q59240Peroxisome proliferator-activated receptor gamma/0.443
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.443
2xpuTDCTetracycline repressor protein class D/0.443
3a3bRBFLumazine protein/0.443
3aidARQGag-Pol polyprotein3.4.23.160.443
3mdmFJZCholesterol 24-hydroxylase/0.443
3mvm39PMitogen-activated protein kinase 14/0.443
3oqkS52Renin3.4.23.150.443
3qj5022Alcohol dehydrogenase class-31.1.1.10.443
3t14FADSulfide-quinone reductase/0.443
3vfa031Gag-Pol polyprotein3.4.23.160.443
3wswNADL-lactate dehydrogenase/0.443
4ejvLCLTranscriptional regulator TcaR/0.443
4g95OAGDihydrofolate reductase1.5.1.30.443
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4gk2L66Ephrin type-A receptor 32.7.10.10.443
4l4fCAMCamphor 5-monooxygenase1.14.15.10.443
4nmcFADBifunctional protein PutA/0.443
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.443
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.443
4xguADPPutative pachytene checkpoint protein 2/0.443
5c41ACPRibokinase/0.443
1bdmNAXMalate dehydrogenase/0.442
1culFOKAdenylate cyclase type 2/0.442
1culFOKAdenylate cyclase type 5/0.442
1ddsMTXDihydrofolate reductase1.5.1.30.442
1draMTXDihydrofolate reductase1.5.1.30.442
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.442
1yqdNAPSinapyl alcohol dehydrogenase/0.442
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.442
2rg6287Mitogen-activated protein kinase 14/0.442
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.442
3bv2P38Mitogen-activated protein kinase 14/0.442
3kb6NADD-lactate dehydrogenase/0.442
3pftFMNFlavin reductase/0.442
3qt62P0Mevalonate diphosphate decarboxylase/0.442
3vt7VDXVitamin D3 receptor/0.442
3w0gW07Vitamin D3 receptor/0.442
4e8yIHAD-beta-D-heptose 7-phosphate kinase/0.442
4eu5COASuccinyl-CoA:acetate CoA-transferase/0.442
4g090VDHistidinol dehydrogenase/0.442
4m9aFDAAcyl-CoA dehydrogenase/0.442
4tsrIHSPeriplasmic AppA protein3.1.3.20.442
4uymVOR14-alpha sterol demethylase Cyp51B/0.442
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.441
1c1dNAIPhenylalanine dehydrogenase/0.441
1dhrNADDihydropteridine reductase1.5.1.340.441
1fm4DXCMajor pollen allergen Bet v 1-L/0.441
1g63FMNEpidermin decarboxylase4.1.10.441
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.441
1h74ADPHomoserine kinase2.7.1.390.441
1hzjUD1UDP-glucose 4-epimerase/0.441
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1obbNADAlpha-glucosidase3.2.1.200.441
1vsvNADGlyceraldehyde-3-phosphate dehydrogenase/0.441
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.441
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.441
2nnhREACytochrome P450 2C8/0.441
3a0tADPSensor histidine kinase/0.441
3a9wNADNDP-sugar epimerase/0.441
3atyFMNProstaglandin F2a synthase/0.441
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.441
3gfbNADL-threonine 3-dehydrogenase/0.441
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3k6l2BBPeptide deformylase3.5.1.880.441
3litE15Protease/0.441
3qrmNK7Gag-Pol polyprotein3.4.23.160.441
3s1dZIRCytokinin dehydrogenase 11.5.99.120.441
3sl2ATPSensor histidine kinase WalK/0.441
3zhxFM61-deoxy-D-xylulose 5-phosphate reductoisomerase/0.441
4egbNADdTDP-glucose 4,6-dehydratase/0.441
1adfTADAlcohol dehydrogenase E chain1.1.1.10.440
1eupASD6-deoxyerythronolide B hydroxylase/0.440
1jolFFODihydrofolate reductase1.5.1.30.440
1kfbIGPTryptophan synthase alpha chain/0.440
1mxtFAECholesterol oxidase1.1.3.60.440
1rf7DHFDihydrofolate reductase1.5.1.30.440
1t2cNAIL-lactate dehydrogenase1.1.1.270.440
2bi4NADLactaldehyde reductase1.1.1.770.440
2hqpNDPDihydrofolate reductase1.5.1.30.440
2pauD5M5'-deoxynucleotidase YfbR/0.440
2x7bCOAN-alpha-acetyltransferase2.3.10.440
2x8hFADThioredoxin glutathione reductase/0.440
3bgbLJGGag-Pol polyprotein3.4.23.160.440
3h3qH13Collagen type IV alpha-3-binding protein/0.440
3so9017Pol protein/0.440
3syiFADSulfide-quinone reductase/0.440
3to6LYS_CMCHistone acetyltransferase ESA1/0.440
3vtdTKDVitamin D3 receptor/0.440
4dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.440
4df2FMNNADPH dehydrogenase/0.440
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.440
4f650S9Fibroblast growth factor receptor 1/0.440
4g7gVFVLanosterol 14-alpha-demethylase/0.440
4idgNADPutative UDP-glucose 4-epimerase/0.440
4iteTEYVitamin D3 receptor/0.440
4q72FADBifunctional protein PutA/0.440
5eoxADPType 4 fimbrial biogenesis protein PilM/0.440
5kghACOPredicted acetyltransferase/0.440