sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 1.000 | |
| 4e5p | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.557 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.484 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.482 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.457 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.449 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.447 | |
| 2hay | FMN | Putative NAD(P)H-flavin oxidoreductase | / | 0.445 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.445 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.445 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.443 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.442 |