scPDB - Distribution of Binding site Similarity values of 4e4n entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4e4n	0NL	Tyrosine-protein kinase JAK1

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4e4n	0NL	Tyrosine-protein kinase JAK1	/	1.000
4ivb	1J5	Tyrosine-protein kinase JAK1	/	0.508
4e6d	0NU	Tyrosine-protein kinase JAK2	/	0.489
4i5c	C5I	Tyrosine-protein kinase JAK1	/	0.486
4e6q	0NV	Tyrosine-protein kinase JAK2	/	0.483
4qny	ANP	Mitogen activated protein kinase, putative	/	0.481
4ei4	0Q2	Tyrosine-protein kinase JAK1	/	0.465
4ii5	ADP	Cyclin-dependent kinase 2	2.7.11.22	0.450
3i4b	Z48	Glycogen synthase kinase-3 beta	2.7.11.26	0.440