sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4e03 | ADP | Plasmid partitioning protein ParF |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4e03 | ADP | Plasmid partitioning protein ParF | / | 1.000 | |
| 4dzz | ADP | Plasmid partitioning protein ParF | / | 0.661 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.483 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.477 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.476 | |
| 5k5z | ANP | Uncharacterized protein | / | 0.470 | |
| 5aga | ANP | DNA polymerase theta | / | 0.469 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.465 | |
| 4v02 | ATP | Site-determining protein | / | 0.459 | |
| 4ohx | ADP | Protein clpf-1 | / | 0.458 | |
| 4oi2 | ADP | Protein clpf-1 | / | 0.458 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.456 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.454 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.453 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.453 | |
| 3r4b | 74T | Gag-Pol polyprotein | / | 0.452 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.451 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.450 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.449 | |
| 3eof | FMN | Putative oxidase | / | 0.449 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.448 | |
| 1w5s | ADP | ORC1-type DNA replication protein 2 | / | 0.447 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.446 | |
| 4y8v | ADP | Acyl-CoA synthetase (NDP forming) | / | 0.446 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.444 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.444 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.443 | |
| 3a37 | ADP | ATPase GET3 | / | 0.441 | |
| 3a3g | DLZ | Lumazine protein | / | 0.441 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.441 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.440 | |
| 3pxv | FMN | Nitroreductase | / | 0.440 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.440 |