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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.11.000
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.81.000
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.525
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.525
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.517
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.517
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.515
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.515
4fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.511
4fapARDSerine/threonine-protein kinase mTOR2.7.11.10.511
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.508
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.508
4driRAPSerine/threonine-protein kinase mTOR2.7.11.10.500
4driRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.500
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.475
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.475