Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4dltGNPGTPase HRas

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4dltGNPGTPase HRas/1.000
3lbhGNPGTPase HRas/0.751
3rs4GNPGTPase HRas/0.729
3lbnGNPGTPase HRas/0.722
4dlwGNPGTPase HRas/0.698
3lbiGNPGTPase HRas/0.697
3ddcGNPGTPase HRas/0.648
3i3sGNPGTPase HRas/0.643
3v4fGNPGTPase HRas/0.630
3k8yGNPGTPase HRas/0.627
3oiuGNPGTPase HRas/0.621
4nyiGNPGTPase HRas/0.621
3rslGNPGTPase HRas/0.619
3pitGNPRas-related protein M-Ras/0.612
4lhwGNPRas-related protein Rab-8A/0.611
3oesGNPGTPase RhebL1/0.605
2rgeGNPGTPase HRas/0.598
5dhaGNPGTP-binding nuclear protein Ran/0.594
4qxaGTPRas-related protein Rab-9A/0.593
4l9sGDPGTPase HRas/0.592
3rs7GNPGTPase HRas/0.587
1ibrGNPGTP-binding nuclear protein Ran/0.586
4rkfGNPRas-related protein Rab-3/0.584
3oivGNPGTPase HRas/0.583
3tsoGNPRas-related protein Rab-25/0.581
3e5hGNPRas-related protein Rab-28/0.580
3rabGNPRas-related protein Rab-3A/0.580
5b2zGNPGTPase HRas/0.579
1g17GNPRas-related protein SEC4/0.578
4nyjGNPGTPase HRas/0.578
3l8yGNPGTPase HRas/0.577
2c5lGTPGTPase HRas/0.576
4dsnGCPGTPase KRas/0.575
2rgcGNPGTPase HRas/0.574
2x19GTPGTP-binding nuclear protein GSP1/CNR1/0.572
2zetGTPRas-related protein Rab-27B/0.572
4mitGTPRho-related protein racC/0.572
5jljGNPGTP-binding nuclear protein Ran/0.572
4k81GTPGTPase HRas/0.571
1xtsGTPGTP-binding protein Rheb/0.570
1zbdGTPRas-related protein Rab-3A/0.570
3kucGDPRas-related protein Rap-1A/0.570
4g0nGNPGTPase HRas/0.569
3kkoGNPRas-related protein M-Ras/0.567
3oiwGNPGTPase HRas/0.565
1t91GTPRas-related protein Rab-7a/0.562
3rs0GNPGTPase HRas/0.561
1zc4GNPRas-related protein Ral-A/0.559
1e96GTPRas-related C3 botulinum toxin substrate 1/0.558
1kmqGNPTransforming protein RhoA/0.557
1yzqGNPRas-related protein Rab-6A/0.557
3x1zGNPRas-related protein Rap-1b/0.557
1xtrGNPGTP-binding protein Rheb/0.556
3a58GNPGTP-binding protein RHO1/0.556
3sbdGNPRas-related C3 botulinum toxin substrate 1/0.556
3w3zGTPGTP-binding nuclear protein Ran/0.556
4cymGCPRas-related protein Rab-32/0.556
3nbzGTPGTP-binding nuclear protein Ran/0.555
2fe4GDPRas-related protein Rab-6B/0.553
4l9wGNPGTPase HRas/0.553
1vg8GNPRas-related protein Rab-7a/0.552
1zc3GNPRas-related protein Ral-A/0.546
3kudGDPGTPase HRas/0.543
1mh1GNPRas-related C3 botulinum toxin substrate 1/0.541
3qbtGNPRas-related protein Rab-8A/0.541
3a6pGTPGTP-binding nuclear protein Ran/0.539
2gilGTPRas-related protein Rab-6A/0.538
3ea5GDPGTP-binding nuclear protein Ran/0.538
4uj3GNPRas-related protein Rab-11A/0.536
2rgbGNPGTPase HRas/0.535
3bbpGTPRas-related protein Rab-6A/0.535
4hdoGNPRas-related protein Rap-1b/0.535
3sbeGNPRas-related C3 botulinum toxin substrate 1/0.532
1zd9GDPADP-ribosylation factor-like protein 8A/0.531
4o25GTPGTP-binding protein Rheb/0.531
5difGNPGTP-binding nuclear protein Ran/0.531
3bc1GNPRas-related protein Rab-27A/0.530
3kz1GSPTransforming protein RhoA/0.530
1a2bGSPTransforming protein RhoA/0.528
2clsGTPRho-related GTP-binding protein Rho6/0.522
1yhnGTPRas-related protein Rab-7a/0.521
3lawGNPRas-related protein Rab-7a/0.521
3rs5GNPGTPase HRas/0.521
2qmeGCPRas-related C3 botulinum toxin substrate 3/0.518
5hpyGDPTransforming protein RhoA/0.516
2ov2GCPRas-related C3 botulinum toxin substrate 3/0.515
1oixGDPRas-related protein Rab-11A/0.513
1uadGNPRas-related protein Ral-A/0.513
2bkuGTPGTP-binding nuclear protein Ran/0.513
4hdqGNPRas-related protein Rap-1b/0.513
1cxzGSPTransforming protein RhoA/0.512
2w2xGSPRas-related C3 botulinum toxin substrate 2/0.512
4dsoGSPGTPase KRas/0.511
3tgpGNPGTPase HRas/0.510
4ol0GTPGTP-binding nuclear protein Ran/0.510
4tq9GDPGTPase KRas/0.509
2fjuGSPRas-related C3 botulinum toxin substrate 1/0.508
1m7bGTPRho-related GTP-binding protein RhoE/0.507
3mjhGTPRas-related protein Rab-5A/0.504
4kvgGTPRas-related protein Rap-1A/0.504
3tnfGNPRas-related protein Rab-8A/0.503
2ffqGSPRas-related protein Rab-6B/0.502
3tklGTPRas-related protein Rab-1A/0.501
4dlzGNPGTPase HRas/0.500
1ow3GDPTransforming protein RhoA/0.497
4dlsGNPGTPase HRas/0.497
4o2rGDPGTP-binding protein Rheb/0.497
1k5dGNPGTP-binding nuclear protein Ran/0.495
4lucGDPGTPase KRas/0.494
2cl6CAGGTPase HRas/0.493
3wyfGTPGTP-binding nuclear protein/0.493
4xvrGNPGTPase HRas/0.493
4l8gGDPGTPase KRas/0.491
4lpkGDPGTPase KRas/0.491
1z2aGDPRas-related protein Rab-23/0.488
4xvqGNPGTPase HRas/0.488
1lfdGNPGTPase HRas/0.487
4dlvGNPGTPase HRas/0.487
1s1cGNPTransforming protein RhoA/0.486
4dxaGSPRas-related protein Rap-1b/0.486
1x1rGDPRas-related protein M-Ras/0.485
2gcpGSPRho-related GTP-binding protein RhoC/0.485
3eg5GNPCell division control protein 42 homolog/0.485
4dlxGNPGTPase HRas/0.485
4epxGDPGTPase KRas/0.485
4o2lGTPGTP-binding protein Rheb/0.483
4xoiGTPTransforming protein RhoA/0.483
5c46GSPRas-related protein Rab-11A/0.483
1z0aGDPRas-related protein Rab-2A/0.482
4dsuGDPGTPase KRas/0.481
4q03GDPGTPase KRas/0.481
1yu9GNPRas-related protein Rab-4A/0.480
3th5GNPRas-related C3 botulinum toxin substrate 1/0.479
2rggGNPGTPase HRas/0.477
2gvdGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.476
4uj5GNPRas-related protein Rab-11A/0.476
4js0GNPCell division control protein 42 homolog/0.473
3x1wGDPRas-related protein Rap-1b/0.472
4lv6GDPGTPase KRas/0.472
4ql3GDPGTPase KRas/0.471
2ce2GDPGTPase HRas/0.469
1n6lGTPRas-related protein Rab-5A/0.468
1d5cGDPGTPase (Rab6)/0.465
3kkqGDPRas-related protein M-Ras/0.465
4epwGDPGTPase KRas/0.463
4wa7GDPGTPase KRas/0.463
1gwnGTPRho-related GTP-binding protein RhoE/0.462
3k9lGNPGTPase HRas/0.462
4gzlGNPRas-related C3 botulinum toxin substrate 1/0.461
4obeGDPGTPase KRas/0.460
1z2cGNPRho-related GTP-binding protein RhoC/0.459
3cphGDPRas-related protein SEC4/0.459
4lrwGDPGTPase KRas/0.457
1eioGCHGastrotropin/0.453
4oi2ADPProtein clpf-1/0.453
4ldjGDPGTPase KRas/0.451
4cidANPEH domain-containing protein 2/0.450
2ic5GNPRas-related C3 botulinum toxin substrate 3/0.449
2msdGNPMHC class I alpha chain/0.447
4ohxADPProtein clpf-1/0.447
1g16GDPRas-related protein SEC4/0.445
3c14GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.442
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.441
2q3fGNPRas-related GTP-binding protein D/0.441
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.441
2fg5GNPRas-related protein Rab-31/0.440
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440