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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4dfk0L5DNA polymerase I, thermostable2.7.7.7

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4dfk0L5DNA polymerase I, thermostable2.7.7.71.000
4df80L4DNA polymerase I, thermostable2.7.7.70.615
3t3fN5PDNA polymerase I, thermostable2.7.7.70.590
4df40L3DNA polymerase I, thermostable2.7.7.70.581
1qtmTTPDNA polymerase I, thermostable2.7.7.70.555
1qsyDDSDNA polymerase I, thermostable2.7.7.70.538
1qssDG3DNA polymerase I, thermostable2.7.7.70.506