Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4de50JDPantothenate synthetase6.3.2.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4de50JDPantothenate synthetase6.3.2.11.000
3ivgFG5Pantothenate synthetase6.3.2.10.716
3iodA6DPantothenate synthetase6.3.2.10.658
3imeBZ2Pantothenate synthetase6.3.2.10.653
3iobA4DPantothenate synthetase6.3.2.10.647
3isjA8DPantothenate synthetase6.3.2.10.615
1n2hPAJPantothenate synthetase6.3.2.10.606
5hg0SAMPantothenate synthetase/0.593
3iocA5DPantothenate synthetase6.3.2.10.590
3ioeA7DPantothenate synthetase6.3.2.10.588
3ivcFG4Pantothenate synthetase6.3.2.10.579
3coz54HPantothenate synthetase6.3.2.10.573
3coy53HPantothenate synthetase6.3.2.10.570
1n2iPAJPantothenate synthetase6.3.2.10.562
3ivxFG6Pantothenate synthetase6.3.2.10.562
3imgBZ2Pantothenate synthetase6.3.2.10.561
1n2jPAFPantothenate synthetase6.3.2.10.552
2x3fAPCPantothenate synthetase/0.532
4ddhMS0Pantothenate synthetase6.3.2.10.531
3ag6PAJPantothenate synthetase/0.527
5kwvANPPantothenate synthetase/0.500
3cow52HPantothenate synthetase6.3.2.10.491
1n2bPAFPantothenate synthetase6.3.2.10.489
2p83MR0Beta-secretase 13.4.23.460.478
5f8eSAHPossible transcriptional regulatory protein/0.477
1kp3ATPArgininosuccinate synthase6.3.4.50.473
1n2gAPCPantothenate synthetase6.3.2.10.473
3udn09BBeta-secretase 13.4.23.460.469
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.468
3imgBZ3Pantothenate synthetase6.3.2.10.468
4yqfGDPSeptin-9/0.468
1gegNADDiacetyl reductase [(S)-acetoin forming]1.1.1.3040.465
1vikBAYGag-Pol polyprotein/0.464
2cv2GSUGlutamate--tRNA ligase6.1.1.170.464
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.464
2vceU2FUDP-glycosyltransferase 72B1/0.463
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.463
1kqnNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.462
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.461
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.461
2gv8NDPThiol-specific monooxygenase1.14.130.460
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
3d91REMRenin3.4.23.150.460
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.460
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3ohh3HHBeta-secretase 13.4.23.460.459
4djhJDCKappa-type opioid receptor/0.459
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.457
4dnaFADProbable glutathione reductase/0.457
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.457
3h3qH13Collagen type IV alpha-3-binding protein/0.456
3ieuGDPGTPase Era/0.456
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.456
2a84ATPPantothenate synthetase6.3.2.10.455
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2bf4FMNNADPH--cytochrome P450 reductase/0.454
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2fhnBNIAvidin-related protein 4/5/0.454
3ix8TX3Transcriptional activator protein LasR/0.454
1k22MELProthrombin3.4.21.50.453
1kquBR4Phospholipase A2, membrane associated/0.453
2iqgF2IBeta-secretase 13.4.23.460.453
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.453
3qe2FMNNADPH--cytochrome P450 reductase/0.453
1khrVIRStreptogramin A acetyltransferase2.3.10.452
4yaoFMNNADPH--cytochrome P450 reductase/0.452
2dxiATPGlutamate--tRNA ligase6.1.1.170.451
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.451
3mauEXTPutative sphingosine-1-phosphate lyase/0.451
3pwm017Gag-Pol polyprotein3.4.23.160.451
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.450
3ix3OHNTranscriptional activator protein LasR/0.450
1bim0QBRenin3.4.23.150.449
1e82M90Endothiapepsin3.4.23.220.449
1rj9GCPSignal recognition particle receptor FtsY/0.449
2c12FADNitroalkane oxidase1.7.3.10.449
4opgFDAConserved Archaeal protein/0.449
1gaxVAAValine--tRNA ligase6.1.1.90.448
1k7fIAVTryptophan synthase alpha chain/0.448
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
1h73ANPHomoserine kinase2.7.1.390.447
2a94AP0L-lactate dehydrogenase1.1.1.270.447
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.447
2p3b3TLV-1 PROTEASE protein/0.447
2p3b3TLV-1 protease/0.447
3i5xANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.447
3r7kFDAProbable acyl CoA dehydrogenase/0.447
4exg916Beta-secretase 13.4.23.460.447
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.447
1hbvGANGag-Pol polyprotein/0.446
3lqsPSZD-alanine aminotransferase2.6.1.210.445
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.444
3qfrFMNNADPH--cytochrome P450 reductase/0.444
3h6vNS6Glutamate receptor 2/0.443
3nd6ATPPhosphopantetheine adenylyltransferase/0.443
3tog079Gag-Pol polyprotein2.7.7.490.443
4ambDUDPutative glycosyl transferase/0.443
1bxsNADRetinal dehydrogenase 11.2.1.360.442
1tj2FADBifunctional protein PutA1.5.5.20.442
3lm9ADPPutative fructokinase2.7.1.40.442
3lzs017Gag-Pol polyprotein3.4.23.160.442
3p1799PProthrombin3.4.21.50.442
1ja0FMNNADPH--cytochrome P450 reductase/0.441
2hrbNAPCarbonyl reductase [NADPH] 31.1.1.1840.441
2ojg19AMitogen-activated protein kinase 12.7.11.240.441
3elySAHMethyltransferase/0.441
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.441
4ntdFADThioredoxin reductase/0.441
4qofFMNRibosyldihydronicotinamide dehydrogenase [quinone]/0.441
1djnADPTrimethylamine dehydrogenase1.5.8.20.440
1ja1FMNNADPH--cytochrome P450 reductase/0.440
1kvkATPMevalonate kinase2.7.1.360.440
1nzq162Prothrombin3.4.21.50.440
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.440
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.440
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.440
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3qto10PProthrombin3.4.21.50.440
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.440