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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4cymGCPRas-related protein Rab-32

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4cymGCPRas-related protein Rab-32/1.000
2gilGTPRas-related protein Rab-6A/0.541
3oesGNPGTPase RhebL1/0.516
2ffqGSPRas-related protein Rab-6B/0.509
3e5hGNPRas-related protein Rab-28/0.506
2clsGTPRho-related GTP-binding protein Rho6/0.504
1xtsGTPGTP-binding protein Rheb/0.489
1yzqGNPRas-related protein Rab-6A/0.487
1zc3GNPRas-related protein Ral-A/0.485
1xtrGNPGTP-binding protein Rheb/0.475
1zbdGTPRas-related protein Rab-3A/0.470
3lawGNPRas-related protein Rab-7a/0.462
3lbnGNPGTPase HRas/0.460
3bbpGTPRas-related protein Rab-6A/0.457
1t91GTPRas-related protein Rab-7a/0.454
2fe4GDPRas-related protein Rab-6B/0.454
4lhwGNPRas-related protein Rab-8A/0.452
2x19GTPGTP-binding nuclear protein GSP1/CNR1/0.449
3tnfGNPRas-related protein Rab-8A/0.449
1zc4GNPRas-related protein Ral-A/0.448
3tklGTPRas-related protein Rab-1A/0.448
3nbzGTPGTP-binding nuclear protein Ran/0.447
1m7bGTPRho-related GTP-binding protein RhoE/0.445
2ov2GCPRas-related C3 botulinum toxin substrate 3/0.444
2zetGTPRas-related protein Rab-27B/0.441