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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4cmfPXGUncharacterized protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4cmfPXGUncharacterized protein/1.000
4uugPXGBranched-chain amino acid aminotransferase, putative/0.515
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.462
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.454
2g1r3IGRenin3.4.23.150.450
1rfuADPPyridoxal kinase2.7.1.350.449
3keuATPPyridoxal kinase2.7.1.350.445
1rneC60Renin3.4.23.150.442
1u1gBBBUridine phosphorylase2.4.2.30.442
3fhyATPPyridoxal kinase2.7.1.350.440