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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.11.000
3lfeZ84Mitogen-activated protein kinase 14/0.560
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.557
2ofv242Tyrosine-protein kinase Lck2.7.10.20.548
2pl0STITyrosine-protein kinase Lck2.7.10.20.546
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.544
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.536
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.534
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.527
2oh4GIGVascular endothelial growth factor receptor 22.7.10.10.514
3d7zGK5Mitogen-activated protein kinase 14/0.512
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.510
4twnB96Ephrin type-A receptor 32.7.10.10.508
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.507
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.506
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.506
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.505
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.502
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.501
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.500
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.498
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.498
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.495
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.494
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.494
3up0D7SaceDAF-12/0.494
2bu9HFVIsopenicillin N synthase1.21.3.10.493
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.491
2oscMUHAngiopoietin-1 receptor2.7.10.10.489
1pqc444Oxysterols receptor LXR-beta/0.488
1obnASVIsopenicillin N synthase1.21.3.10.487
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.487
3qakUKAAdenosine receptor A2a/0.487
2po7CHDFerrochelatase, mitochondrial4.99.1.10.485
2qu5276Vascular endothelial growth factor receptor 22.7.10.10.485
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.485
3ac2KSETyrosine-protein kinase Lck2.7.10.20.484
4bb3KKAIsopenicillin N synthase1.21.3.10.484
3emlZMAAdenosine receptor A2a/0.483
1bucFADAcyl-CoA dehydrogenase, short-chain specific1.3.8.10.482
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.482
2i0v6C3Macrophage colony-stimulating factor 1 receptor2.7.10.10.482
2jddACOProbable acetyltransferase/0.482
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.481
2vbdV10Isopenicillin N synthase1.21.3.10.481
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.479
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.479
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.479
5g53NECAdenosine receptor A2a/0.479
5iu86DZAdenosine receptor A2a/0.479
1hb3SCVIsopenicillin N synthase1.21.3.10.478
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.478
2w5bAGSSerine/threonine-protein kinase Nek22.7.11.10.478
4qms1N1Serine/threonine-protein kinase 242.7.11.10.478
1uzwCDHIsopenicillin N synthase1.21.3.10.477
2imkGTXAGAP009194-PA/0.477
2jb4A14Isopenicillin N synthase1.21.3.10.477
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.477
2vbpVB1Isopenicillin N synthase1.21.3.10.477
3gcq1BUMitogen-activated protein kinase 14/0.477
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.477
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.476
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.476
3p6nDSOCamphor 5-monooxygenase1.14.15.10.476
2i5nUQ1Reaction center protein L chain/0.475
4gk2L66Ephrin type-A receptor 32.7.10.10.475
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.474
3l6jZ90Alr2278 protein/0.474
1blzACVIsopenicillin N synthase1.21.3.10.473
1eiiRTLRetinol-binding protein 2/0.473
1p8dCO1Oxysterols receptor LXR-beta/0.473
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
3zkyWT4Isopenicillin N synthase1.21.3.10.473
4l5b1UXDeoxycytidine kinase2.7.1.740.473
1fm4DXCMajor pollen allergen Bet v 1-L/0.472
2iviACWIsopenicillin N synthase1.21.3.10.472
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.472
3uzcT4EAdenosine receptor A2a/0.472
1dgfNDPCatalase1.11.1.60.471
2g78REACellular retinoic acid-binding protein 2/0.471
2rqfJH3Hemolymph juvenile hormone binding protein/0.471
2zevB71Geranylgeranyl pyrophosphate synthase/0.471
4iae1DXAlr2278 protein/0.471
4iah1DXAlr2278 protein/0.471
1upw444Oxysterols receptor LXR-beta/0.470
3itzP66Mitogen-activated protein kinase 14/0.470
4jvlESTEstrogen sulfotransferase2.8.2.40.470
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.469
1w06W05Isopenicillin N synthase1.21.3.10.469
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.469
3cqeP91Wee1-like protein kinase2.7.10.20.469
3hub469Mitogen-activated protein kinase 14/0.469
5k2aZMAAdenosine receptor A2a/0.469
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.468
3ac1KZITyrosine-protein kinase Lck2.7.10.20.468
3qri919Tyrosine-protein kinase ABL12.7.10.20.468
1oc1ASVIsopenicillin N synthase1.21.3.10.467
1qjfACSIsopenicillin N synthase1.21.3.10.467
4a81DXCMajor pollen allergen Bet v 1-A/0.467
1bk0ACVIsopenicillin N synthase1.21.3.10.466
1cqp803Integrin alpha-L/0.466
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.466
2wo7ASVIsopenicillin N synthase1.21.3.10.466
3cth319Hepatocyte growth factor receptor2.7.10.10.466
3gkjHC3Niemann-Pick C1 protein/0.466
3p3zP3ZPutative cytochrome P450/0.466
3qczANPDihydrofolate synthase/folylpolyglutamate synthase/0.466
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.466
2x7hPFNProstaglandin reductase 310.465
3gkiCLRNiemann-Pick C1 protein/0.465
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.465
5bt42LOBromodomain-containing protein 4/0.465
1dajMOTDihydrofolate reductase1.5.1.30.464
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.464
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
3jynNDPQuinone oxidoreductase/0.464
3owuEQUSteroid Delta-isomerase5.3.3.10.464
3tdaPN0Cytochrome P450 2D6/0.464
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.464
1cbqRE9Cellular retinoic acid-binding protein 2/0.463
1qiqACCIsopenicillin N synthase1.21.3.10.463
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.463
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
3a783EVVitamin D3 receptor/0.463
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.463
5cc9DDFDihydrofolate reductase1.5.1.30.463
5k2cZMAAdenosine receptor A2a/0.463
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
2y6fM9FIsopenicillin N synthase1.21.3.10.462
3a1l2CCCytochrome P450/0.462
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.462
3h4vDVPPteridine reductase 11.5.1.330.462
3hv3R49Mitogen-activated protein kinase 14/0.462
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.462
3w0gW07Vitamin D3 receptor/0.462
4a83DXCMajor pollen allergen Bet v 1-A/0.462
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.462
4hvs647Mast/stem cell growth factor receptor Kit2.7.10.10.462
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
2vcmM11Isopenicillin N synthase1.21.3.10.461
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.461
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.461
4jlm1NNDeoxycytidine kinase2.7.1.740.461
4jln18VDeoxycytidine kinase2.7.1.740.461
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.461
4v010LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b/0.461
1dghNDPCatalase1.11.1.60.460
1pkfEPDEpothilone C/D epoxidase1.140.460
1rrmAPRLactaldehyde reductase1.1.1.770.460
2aazCB3Thymidylate synthase2.1.1.450.460
3ol5SAWCamphor 5-monooxygenase1.14.15.10.460
3p2oNADBifunctional protein FolD/0.460
3p6pA6BCamphor 5-monooxygenase1.14.15.10.460
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
4equG6ISerine/threonine-protein kinase 102.7.11.10.460
4jqh1MFAlr2278 protein/0.460
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.460
4y8vADPAcyl-CoA synthetase (NDP forming)/0.460
3uzaT4GAdenosine receptor A2a/0.460
1cbsREACellular retinoic acid-binding protein 2/0.459
1h42FADFerredoxin--NADP reductase1.18.1.20.459
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1osvCHCBile acid receptor/0.459
1xddAAYIntegrin alpha-L/0.459
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
3ghvGHCDihydrofolate reductase1.5.1.30.459
3pyzANPDihydrofolate synthase/folylpolyglutamate synthase/0.459
1mc5AHEAlcohol dehydrogenase class-31.1.1.10.458
1pq944BOxysterols receptor LXR-beta/0.458
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
2r6jNDPEugenol synthase 11.1.1.3180.458
2zb1GK4Mitogen-activated protein kinase 14/0.458
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
3rfmCFFAdenosine receptor A2a/0.458
1hb1OCVIsopenicillin N synthase1.21.3.10.457
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.457
2aibERGBeta-elicitin cinnamomin/0.457
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2gfsPQBMitogen-activated protein kinase 14/0.457
2hveADPNucleoside diphosphate kinase A2.7.4.60.457
3c3xNAPEugenol synthase 11.1.1.3180.457
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.457
3k4nFADPyranose 2-oxidase/0.457
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.457
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.457
3w0hW12Vitamin D3 receptor/0.457
4bj9UHBTankyrase-22.4.2.300.457
4g2fC07Ephrin type-A receptor 32.7.10.10.457
1e7aPFLSerum albumin/0.456
1gqyACPUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.456
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.456
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.456
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
2oz57XYUncharacterized protein/0.456
2r0pK2CPutative FAD-monooxygenase/0.456
2z2w770Wee1-like protein kinase2.7.10.20.456
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.456
3e92G6AMitogen-activated protein kinase 14/0.456
3g7fUQ1Reaction center protein L chain/0.456
3l0lHC3Nuclear receptor ROR-gamma/0.456
4dsbA8SAbscisic acid receptor PYL3/0.456
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.456
4iaq2GM5-hydroxytryptamine receptor 1B/0.456
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.456
4r20AERCytochrome P450 family 17 polypeptide 2/0.456
1cbrREACellular retinoic acid-binding protein 1/0.455
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
2balPQAMitogen-activated protein kinase 14/0.455
2ewaSB2Mitogen-activated protein kinase 14/0.455
2ydoADNAdenosine receptor A2a/0.455
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.455
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
4dscA8SAbscisic acid receptor PYL3/0.455
1d3pBT3Prothrombin3.4.21.50.454
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.454
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.454
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.454
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.454
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.454
4dvi2IWTankyrase-12.4.2.300.454
4pd6URINucleoside permease/0.454
5k2bZMAAdenosine receptor A2a/0.454
5jtbZMAAdenosine receptor A2a/0.454
1mrqSTRAldo-keto reductase family 1 member C1/0.453
1ot7CHCBile acid receptor/0.453
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.453
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.453
2bbqPFGThymidylate synthase/0.453
2jdcCAOProbable acetyltransferase/0.453
2pnuENMAndrogen receptor/0.453
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.453
3eigMTXDihydrofolate reductase1.5.1.30.453
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3thrC2FGlycine N-methyltransferase2.1.1.200.453
3uk6ADPRuvB-like 23.6.4.120.453
3up3XCAaceDAF-12/0.453
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.453
3zoiM2WIsopenicillin N synthase1.21.3.10.453
4a4xJUPSerine/threonine-protein kinase Nek22.7.11.10.453
4fdnFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.453
4iarERM5-hydroxytryptamine receptor 1B/0.453
5ab6CAANonspecific lipid-transfer protein, putative/0.453
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
1tduCB3Thymidylate synthase/0.452
1v7aFRCAdenosine deaminase3.5.4.40.452
2d29FADAcyl-CoA dehydrogenase/0.452
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.452
3biz61EWee1-like protein kinase2.7.10.20.452
3h0bB35Beta-secretase 13.4.23.460.452
3iczPB6Farnesyl pyrophosphate synthase/0.452
3p6mDSOCamphor 5-monooxygenase1.14.15.10.452
4a84DXCMajor pollen allergen Bet v 1-A/0.452
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.452
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.452
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.452
4j6dTESCytochrome P450 monooxygenase/0.452
5dozNDPJamJ/0.452
1jomFFODihydrofolate reductase1.5.1.30.451
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.451
1w29TS06,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
1xuoLA1Integrin alpha-L/0.451
1ygjRMCPyridoxal kinase2.7.1.350.451
1zg32HIIsoflavone 4'-O-methyltransferase/0.451
2bakAQZMitogen-activated protein kinase 14/0.451
2io6330Wee1-like protein kinase2.7.10.20.451
2of4979Tyrosine-protein kinase Lck2.7.10.20.451
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.451
3cho4BGLeukotriene A-4 hydrolase3.3.2.60.451
3ds6A17Mitogen-activated protein kinase 14/0.451
3gtsD3MDdmC/0.451
3mjeNDPAmphB/0.451
3nx4NAPPutative oxidoreductase/0.451
4a9yAQZMitogen-activated protein kinase 14/0.451
4at5MUJBDNF/NT-3 growth factors receptor2.7.10.10.451
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
4uugPXGBranched-chain amino acid aminotransferase, putative/0.451
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
5iubCLRAdenosine receptor A2a/0.451
1d3dBZTProthrombin3.4.21.50.450
1w7kADPDihydrofolate synthase/folylpolyglutamate synthase6.3.2.120.450
2agvTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.450
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.450
2vd0D27Hematopoietic prostaglandin D synthase/0.450
3bx5304Mitogen-activated protein kinase 14/0.450
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
3p9tTCLRepressor/0.450
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.450
3w5rLOAVitamin D3 receptor/0.450
4hcy0YNTransketolase/0.450
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.450
4jlj1NMDeoxycytidine kinase2.7.1.740.450
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.450
7catNDPCatalase1.11.1.60.450
1jutLYDThymidylate synthase/0.449
2ed3SAHDiphthine synthase/0.449
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.449
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.449
3nguADPNucleoside diphosphate kinase/0.449
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.449
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.449
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4j6bPLOCytochrome P450 monooxygenase/0.449
4rh10TTSpore photoproduct lyase/0.449
4x5jFOLDihydrofolate reductase1.5.1.30.449
5dc5B3NHistone deacetylase 83.5.1.980.449
1d6w00RProthrombin3.4.21.50.448
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1n9mBTNStreptavidin/0.448
1uydPU8Heat shock protein HSP 90-alpha/0.448
1x8lOXRRetinol dehydratase/0.448
2vd5BI8Myotonin-protein kinase2.7.11.10.448
2xyuQ9GEphrin type-A receptor 42.7.10.10.448
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.448
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.448
3mvm39PMitogen-activated protein kinase 14/0.448
3nx2FERFerulic acid decarboxylase/0.448
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.448
4c1fX8ZMetallo-beta-lactamase type 2/0.448
4eqcXR1Serine/threonine-protein kinase PAK 12.7.11.10.448
4jtrIZPAldo-keto reductase family 1 member C2/0.448
4oztP1AEcdysone receptor, putative/0.448
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.448
4uhrNGIAdenosine receptor A2a/0.448
1cf3FADGlucose oxidase1.1.3.40.447
1u8fNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.447
1x8b824Wee1-like protein kinase2.7.10.20.447
2j9lATPH(+)/Cl(-) exchange transporter 5/0.447
2jedLG8Protein kinase C theta type2.7.11.130.447
2vcwZZAHematopoietic prostaglandin D synthase/0.447
2xkc4VQSerine/threonine-protein kinase Nek22.7.11.10.447
2xkfBX1Serine/threonine-protein kinase Nek22.7.11.10.447
3ar7TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.447
3cbsR12Cellular retinoic acid-binding protein 2/0.447
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3inxJZCHeat shock protein HSP 90-alpha/0.447
3kxoKXOHematopoietic prostaglandin D synthase/0.447
3p99LNPLanosterol 14-alpha-demethylase/0.447
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.447
3vwdACOAlpha-tubulin N-acetyltransferase 1/0.447
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.447
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.447
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4bfwZVWPantothenate kinase2.7.1.330.447
4dk70KSOxysterols receptor LXR-beta/0.447
4n3l2FNProthrombin3.4.21.50.447
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.447
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.447
5k2dZMAAdenosine receptor A2a/0.447
1dgbNDPCatalase1.11.1.60.446
1rf9DBRCamphor 5-monooxygenase1.14.15.10.446
1txtCAAHMG-CoA synthase/0.446
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.446
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.446
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.446
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.446
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.446
4bfvZVVPantothenate kinase2.7.1.330.446
4eh60ONMitogen-activated protein kinase 14/0.446
4gk4L90Ephrin type-A receptor 32.7.10.10.446
4gueQCTRibosomal protein S6 kinase alpha-32.7.11.10.446
4j6cSTRCytochrome P450 monooxygenase/0.446
4klnAGSTransitional endoplasmic reticulum ATPase3.6.4.60.446
1swdBTNStreptavidin/0.445
1yb5NAPQuinone oxidoreductase1.6.5.50.445
2bnsMSTReaction center protein L chain/0.445
2hpsCTZCa2+-triggered coelenterazine-binding protein 1/0.445
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.445
2nnqT4BFatty acid-binding protein, adipocyte/0.445
2p15EZTEstrogen receptor/0.445
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.445
3nu03TUDihydrofolate reductase1.5.1.30.445
3u8hBHPPhospholipase A2, membrane associated/0.445
3v0o4GWHisto-blood group ABO system transferase/0.445
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.445
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.445
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.445
4ia3BIVVitamin D3 receptor A/0.445
4qij1HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.445
5hbsRTLRetinol-binding protein 1/0.445
1disBDMDihydrofolate reductase1.5.1.30.444
1hvyD16Thymidylate synthase2.1.1.450.444
1nbhSAMGlycine N-methyltransferase2.1.1.200.444
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.444
2dvlFADAcyl-CoA dehydrogenase/0.444
2hk51BMTyrosine-protein kinase HCK2.7.10.20.444
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.444
3deiRXBCaspase-33.4.22.560.444
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3kp4MIITranscriptional regulator TcaR/0.444
3ndvAICBeta-peptidyl aminopeptidase BapA/0.444
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3pqbVGPPutative oxidoreductase/0.444
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.444
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.444
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.444
4fhi0S4Vitamin D3 receptor A/0.444
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
4isk1JYThymidylate synthase/0.444
4ryvZEAProtein LlR18A/0.444
4ttjFMCPurine nucleoside phosphorylase DeoD-type/0.444
1drfFOLDihydrofolate reductase1.5.1.30.443
1re9DSOCamphor 5-monooxygenase1.14.15.10.443
2bjsACVIsopenicillin N synthase1.21.3.10.443
2dhfDZFDihydrofolate reductase1.5.1.30.443
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.443
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.443
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.443
2rg6287Mitogen-activated protein kinase 14/0.443
2xk730ESerine/threonine-protein kinase Nek22.7.11.10.443
2z3uCRRCytochrome P450/0.443
3dfrMTXDihydrofolate reductase1.5.1.30.443
3e7iB2Nitric oxide synthase, inducible1.14.13.390.443
3ielU5PRibonuclease TTHA02523.10.443
3njoPYVAbscisic acid receptor PYR1/0.443
3slkNDPPolyketide synthase extender module 2/0.443
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.443
4ez8DHFThymidylate synthase2.1.1.450.443
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.443
4kwi1TJReductase homolog/0.443
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.443
4r21STRCytochrome P450 family 17 polypeptide 2/0.443
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
1dnaCB3Thymidylate synthase/0.442
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1jjtBDSBeta-lactamase/0.442
1lriCLRBeta-elicitin cryptogein/0.442
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.442
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.442
1s7nCOAAcetyl transferase/0.442
2ejzSAHDiphthine synthase/0.442
2ic5GNPRas-related C3 botulinum toxin substrate 3/0.442
2o7pNAPRiboflavin biosynthesis protein RibD/0.442
2uxoTACHTH-type transcriptional regulator TtgR/0.442
2xf3J01Uncharacterized protein/0.442
2y60M8FIsopenicillin N synthase1.21.3.10.442
3abiNADUncharacterized protein/0.442
3e5aVX6Aurora kinase A2.7.11.10.442
3eta351Insulin receptor2.7.10.10.442
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.442
3vi5M4MHematopoietic prostaglandin D synthase/0.442
3vo30KFVascular endothelial growth factor receptor 22.7.10.10.442
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.442
4ia1BIVVitamin D3 receptor A/0.442
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.442
4k4eK4ETankyrase-12.4.2.300.442
4n1fCZHObelin/0.442
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.442
4rvgTYDD-mycarose 3-C-methyltransferase/0.442
4tyj0LIFibroblast growth factor receptor 42.7.10.10.442
5emhNAPIridoid synthase1.3.1.990.442
1dfoFFOSerine hydroxymethyltransferase2.1.2.10.441
1jujLYAThymidylate synthase2.1.1.450.441
1kzuRG1Light-harvesting protein B-800/850 alpha chain/0.441
1kzuRG1Light-harvesting protein B-800/850 beta chain/0.441
1mvtDTMDihydrofolate reductase1.5.1.30.441
1p3dANPUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.441
1w7h3IPMitogen-activated protein kinase 14/0.441
1z6tADPApoptotic protease-activating factor 1/0.441
2bfmTOPPteridine reductase 11.5.1.330.441
2igxA1TPlasmepsin 2/0.441
3arpDEQChitinase A/0.441
3atzFMNProstaglandin F2a synthase/0.441
3cr0809Wee1-like protein kinase2.7.10.20.441
3da24MDCarbonic anhydrase 134.2.1.10.441
3gwfNAPCyclohexanone monooxygenase/0.441
3h3sH15Collagen type IV alpha-3-binding protein/0.441
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.441
3hz5Z64Heat shock protein HSP 90-alpha/0.441
3ntgD72Prostaglandin G/H synthase 21.14.99.10.441
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.441
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4hx519VCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
4l4xNDPAmphI/0.441
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4mv8ACPBiotin carboxylase6.3.4.140.441
5arkUMPRibonuclease 43.1.270.441
1dliUDXUDP-glucose 6-dehydrogenase/0.440
1kt6RTLRetinol-binding protein 4/0.440
1n83CLRNuclear receptor ROR-alpha/0.440
1xkdNAPIsocitrate dehydrogenase [NADP]/0.440
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2r04W71Genome polyprotein/0.440
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.440
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.440
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.440
3aosJH2Hemolymph juvenile hormone binding protein/0.440
3bbfGDPNucleoside diphosphate kinase B2.7.4.60.440
3bgxMEFThymidylate synthase/0.440
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
3qly55VUncharacterized protein/0.440
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.440
4blcNDPCatalase1.11.1.60.440
4hni16WCasein kinase I isoform epsilon2.7.11.10.440
4imwH4BNitric oxide synthase, brain1.14.13.390.440
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.440
4ol0GTPGTP-binding nuclear protein Ran/0.440
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
5fm7ADPRuvB-like helicase/0.440
5uviZMAAdenosine receptor A2a/0.440
4ug2NGIAdenosine receptor A2a/0.440