sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4cid | ANP | EH domain-containing protein 2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4cid | ANP | EH domain-containing protein 2 | / | 1.000 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.522 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.486 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.486 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.485 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.482 | |
| 4nyi | GNP | GTPase HRas | / | 0.480 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.477 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.477 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.474 | |
| 3v4f | GNP | GTPase HRas | / | 0.471 | |
| 3ddc | GNP | GTPase HRas | / | 0.470 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.468 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.467 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.467 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.467 | |
| 3lbn | GNP | GTPase HRas | / | 0.467 | |
| 1tu3 | GNP | Ras-related protein Rab-5A | / | 0.464 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.463 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.460 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.459 | |
| 3wyf | GTP | GTP-binding nuclear protein | / | 0.459 | |
| 3tgp | GNP | GTPase HRas | / | 0.458 | |
| 4l8g | GDP | GTPase KRas | / | 0.458 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.458 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.457 | |
| 3oiv | GNP | GTPase HRas | / | 0.456 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.453 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.453 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.453 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.452 | |
| 2rgg | GNP | GTPase HRas | / | 0.452 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.451 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.451 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.451 | |
| 2rge | GNP | GTPase HRas | / | 0.450 | |
| 1z2a | GDP | Ras-related protein Rab-23 | / | 0.449 | |
| 2cl6 | CAG | GTPase HRas | / | 0.449 | |
| 3lbh | GNP | GTPase HRas | / | 0.449 | |
| 4nyj | GNP | GTPase HRas | / | 0.449 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.448 | |
| 2rgc | GNP | GTPase HRas | / | 0.448 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.447 | |
| 2c5l | GTP | GTPase HRas | / | 0.447 | |
| 4g0n | GNP | GTPase HRas | / | 0.445 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.445 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.444 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.444 | |
| 1yu9 | GNP | Ras-related protein Rab-4A | / | 0.443 | |
| 4dlt | GNP | GTPase HRas | / | 0.443 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.442 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.442 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.440 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.440 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.440 |